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The map label for this gene is fucR [H]

Identifier: 82545103

GI number: 82545103

Start: 2695996

End: 2696727

Strand: Direct

Name: fucR [H]

Synonym: SBO_2688

Alternate gene names: 82545103

Gene position: 2695996-2696727 (Clockwise)

Preceding gene: 82545102

Following gene: 82545108

Centisome position: 59.65

GC content: 48.09

Gene sequence:

>732_bases
ATGAAAGCGGCACGCCAGCAAGCGATAGTCGACCTGCTGCTGAACCATACCAGCCTGACCACGGAAGCTCTCTCTGAACA
GCTAAAGGTCAGTAAAGAAACCATTCGTCGCGATCTCAATGAATTACAGACGCAGGGTAAAATTCTGCGCAATCATGGAC
GCGCTAAATATATCCACCGTCAAAATCAAGACAGTGGCGATCCCTTTCACATCAGGCTGAAAAGCCATTATGCGCATAAA
GCAGATATCGCGCGCGAGGCGCTCGCGTGGATTGAAGAAGGGATGGTGATAGCCTTAGACGCCAGTTCAACTTGCTGGTA
TCTGGCACGCCAGTTGCCTGACATCAACATTCAGGTCTTCACCAATAGCCATCCGATTTGCTATGAACTCGGTAAACGCG
AACGCATTCAACTGATCAGTTCCGGCGGCACACTTGAGCGCAAATATGGCTGTTACGTCAATCCCTCGCTGATTTCCCAA
CTTAAATCGCTGGAAATCGATCTGTTTATTTTTTCTTGTGAAGGGATCGATAGCAGCGGCGCACTGTGGGACTCCAATGC
GATCAACGCTGATTACAAATCGATGCTATTAAAACGTGCCGCGCAATCGTTGTTATTGATTGATAAAAGTAAATTTAATC
GTTCAGGGGAAGCCCGCATCGGGCATCTGGATGAGGTAACGCACATTATTTCTGATGAGCGCCAGGTTGCAACTTCTTTG
GTAACAGCCTGA

Upstream 100 bases:

>100_bases
GAAGTACGGGAATATTCTTTTAAAAAAAGGGGTAACACCGTAATCTCATACCGGTACGCCCGCATGACGCGGGCGGTTAT
CGAATGATGGGGTGAAAAAT

Downstream 100 bases:

>100_bases
CGGAAAGGGTAGCAGGCCGAAGACGACGCCCCGGCCTTGCCTGTTATCGCTCGTCGCGACGACCACCCACCGCAGCCCAG
ATGCGGCGGACGTGCACCGT

Product: DNA-binding transcriptional activator FucR

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 243; Mature: 243

Protein sequence:

>243_residues
MKAARQQAIVDLLLNHTSLTTEALSEQLKVSKETIRRDLNELQTQGKILRNHGRAKYIHRQNQDSGDPFHIRLKSHYAHK
ADIAREALAWIEEGMVIALDASSTCWYLARQLPDINIQVFTNSHPICYELGKRERIQLISSGGTLERKYGCYVNPSLISQ
LKSLEIDLFIFSCEGIDSSGALWDSNAINADYKSMLLKRAAQSLLLIDKSKFNRSGEARIGHLDEVTHIISDERQVATSL
VTA

Sequences:

>Translated_243_residues
MKAARQQAIVDLLLNHTSLTTEALSEQLKVSKETIRRDLNELQTQGKILRNHGRAKYIHRQNQDSGDPFHIRLKSHYAHK
ADIAREALAWIEEGMVIALDASSTCWYLARQLPDINIQVFTNSHPICYELGKRERIQLISSGGTLERKYGCYVNPSLISQ
LKSLEIDLFIFSCEGIDSSGALWDSNAINADYKSMLLKRAAQSLLLIDKSKFNRSGEARIGHLDEVTHIISDERQVATSL
VTA
>Mature_243_residues
MKAARQQAIVDLLLNHTSLTTEALSEQLKVSKETIRRDLNELQTQGKILRNHGRAKYIHRQNQDSGDPFHIRLKSHYAHK
ADIAREALAWIEEGMVIALDASSTCWYLARQLPDINIQVFTNSHPICYELGKRERIQLISSGGTLERKYGCYVNPSLISQ
LKSLEIDLFIFSCEGIDSSGALWDSNAINADYKSMLLKRAAQSLLLIDKSKFNRSGEARIGHLDEVTHIISDERQVATSL
VTA

Specific function: Transcriptional activator of the fuc operon [H]

COG id: COG1349

COG function: function code KG; Transcriptional regulators of sugar metabolism

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH deoR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1789170, Length=243, Percent_Identity=99.5884773662551, Blast_Score=498, Evalue=1e-142,
Organism=Escherichia coli, GI1788069, Length=231, Percent_Identity=32.4675324675325, Blast_Score=111, Evalue=3e-26,
Organism=Escherichia coli, GI1789829, Length=232, Percent_Identity=28.448275862069, Blast_Score=103, Evalue=9e-24,
Organism=Escherichia coli, GI87082344, Length=230, Percent_Identity=28.2608695652174, Blast_Score=95, Evalue=4e-21,
Organism=Escherichia coli, GI1789059, Length=231, Percent_Identity=27.7056277056277, Blast_Score=75, Evalue=6e-15,
Organism=Escherichia coli, GI1787540, Length=240, Percent_Identity=25, Blast_Score=74, Evalue=6e-15,
Organism=Escherichia coli, GI1790753, Length=229, Percent_Identity=23.5807860262009, Blast_Score=73, Evalue=2e-14,
Organism=Escherichia coli, GI1790635, Length=231, Percent_Identity=23.8095238095238, Blast_Score=72, Evalue=2e-14,
Organism=Escherichia coli, GI1789519, Length=239, Percent_Identity=27.6150627615063, Blast_Score=72, Evalue=3e-14,
Organism=Escherichia coli, GI226510968, Length=238, Percent_Identity=26.0504201680672, Blast_Score=65, Evalue=4e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014036
- InterPro:   IPR001034
- InterPro:   IPR018356
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00455 DeoR; PF08220 HTH_DeoR [H]

EC number: NA

Molecular weight: Translated: 27389; Mature: 27389

Theoretical pI: Translated: 8.01; Mature: 8.01

Prosite motif: PS00894 HTH_DEOR_1 ; PS51000 HTH_DEOR_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKAARQQAIVDLLLNHTSLTTEALSEQLKVSKETIRRDLNELQTQGKILRNHGRAKYIHR
CCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEHCC
QNQDSGDPFHIRLKSHYAHKADIAREALAWIEEGMVIALDASSTCWYLARQLPDINIQVF
CCCCCCCCEEEEEECCCCHHHHHHHHHHHHHHCCEEEEEECCCHHHHHHHHCCCCEEEEE
TNSHPICYELGKRERIQLISSGGTLERKYGCYVNPSLISQLKSLEIDLFIFSCEGIDSSG
ECCCCEEECCCCCCEEEEEECCCCEEECCCCEECHHHHHHHHHCEEEEEEEEECCCCCCC
ALWDSNAINADYKSMLLKRAAQSLLLIDKSKFNRSGEARIGHLDEVTHIISDERQVATSL
CEECCCCCCHHHHHHHHHHHHHHHEEEEHHHCCCCCCCCCCHHHHHHHHHCCHHHHHHHH
VTA
HCC
>Mature Secondary Structure
MKAARQQAIVDLLLNHTSLTTEALSEQLKVSKETIRRDLNELQTQGKILRNHGRAKYIHR
CCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEHCC
QNQDSGDPFHIRLKSHYAHKADIAREALAWIEEGMVIALDASSTCWYLARQLPDINIQVF
CCCCCCCCEEEEEECCCCHHHHHHHHHHHHHHCCEEEEEECCCHHHHHHHHCCCCEEEEE
TNSHPICYELGKRERIQLISSGGTLERKYGCYVNPSLISQLKSLEIDLFIFSCEGIDSSG
ECCCCEEECCCCCCEEEEEECCCCEEECCCCEECHHHHHHHHHCEEEEEEEEECCCCCCC
ALWDSNAINADYKSMLLKRAAQSLLLIDKSKFNRSGEARIGHLDEVTHIISDERQVATSL
CEECCCCCCHHHHHHHHHHHHHHHEEEEHHHCCCCCCCCCCHHHHHHHHHCCHHHHHHHH
VTA
HCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 2664711; 9278503 [H]