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The map label for this gene is rseA

Identifier: 82545024

GI number: 82545024

Start: 2605833

End: 2606483

Strand: Reverse

Name: rseA

Synonym: SBO_2600

Alternate gene names: 82545024

Gene position: 2606483-2605833 (Counterclockwise)

Preceding gene: 82545025

Following gene: 82545023

Centisome position: 57.67

GC content: 52.07

Gene sequence:

>651_bases
ATGCAGAAAGAACAACTTTCCGCTTTAATGGATGGCGAAACGCTGGATAGTGAGCTGCTTAACGAACTGGCTCATAACCC
AGAAATGCAGAAAACCTGGGAAAGCTATCACTTAATCCGTGACTCAATGCGGGGTGATACTCCCGAGGTGCTCCATTTCG
ATATCTCTTCACGCGTGATGGCCGCCATTGAAGAAGAGCCAGTACGTCAACCGGCGACATTGATCCCGGAAGCCCAGCCT
GCGCCGCATCAATGGCAGAAAATGCCATTCTGGCAGAAAGTACGTCCGTGGGCGGCACAGCTTACCCAAATGGGCGTAGC
AGCATGCGTATCGCTTGCAGTTATCGTTGGCGTCCAGCACTATAATGGACAATCTGAAACGTCCCAGCAGCCCGAAACGC
CGGTATTTAATACACTGCCGATGATGGGTAAAGCCAGCCCGGTAAGCCTGGGAGTACCTTCTGAAGCGACCGCAAACAAT
GGTCAACAGCAGCAGGTACAGGAGCAGCGTCGTCGCATTAATGCAATGTTGCAGGATTACGAACTGCAACGCCGACTCCA
CTCTGAACAGCTTCAGTTTGAGCAGGCGCAAACCCAGCAAGCCGCTGTACAGGTGCCAGGAATTCAAACTTTAGGAACGC
AATCGCAGTAA

Upstream 100 bases:

>100_bases
TGCGTTCACGTATCTTCCGAGCGAGGGAAGCTATTGATAACAAAGTTCAACCGCTTATCAGGCGTTGACGATAGCGGGAT
ACTGGATAAGGGTATTAGGC

Downstream 100 bases:

>100_bases
TGAAGCAACTTTGGTTTGCCATGTCATTAGTGACAGGTAGCCTGTTATTCTCTGCTAACGCCTCGGCCACTCCCGCGTCC
GGGGCGTTATTACAGCAGAT

Product: anti-RNA polymerase sigma factor SigE

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 216; Mature: 216

Protein sequence:

>216_residues
MQKEQLSALMDGETLDSELLNELAHNPEMQKTWESYHLIRDSMRGDTPEVLHFDISSRVMAAIEEEPVRQPATLIPEAQP
APHQWQKMPFWQKVRPWAAQLTQMGVAACVSLAVIVGVQHYNGQSETSQQPETPVFNTLPMMGKASPVSLGVPSEATANN
GQQQQVQEQRRRINAMLQDYELQRRLHSEQLQFEQAQTQQAAVQVPGIQTLGTQSQ

Sequences:

>Translated_216_residues
MQKEQLSALMDGETLDSELLNELAHNPEMQKTWESYHLIRDSMRGDTPEVLHFDISSRVMAAIEEEPVRQPATLIPEAQP
APHQWQKMPFWQKVRPWAAQLTQMGVAACVSLAVIVGVQHYNGQSETSQQPETPVFNTLPMMGKASPVSLGVPSEATANN
GQQQQVQEQRRRINAMLQDYELQRRLHSEQLQFEQAQTQQAAVQVPGIQTLGTQSQ
>Mature_216_residues
MQKEQLSALMDGETLDSELLNELAHNPEMQKTWESYHLIRDSMRGDTPEVLHFDISSRVMAAIEEEPVRQPATLIPEAQP
APHQWQKMPFWQKVRPWAAQLTQMGVAACVSLAVIVGVQHYNGQSETSQQPETPVFNTLPMMGKASPVSLGVPSEATANN
GQQQQVQEQRRRINAMLQDYELQRRLHSEQLQFEQAQTQQAAVQVPGIQTLGTQSQ

Specific function: Negative regulator of rpoE

COG id: COG3073

COG function: function code T; Negative regulator of sigma E activity

Gene ontology:

Cell location: Cell membrane; Single-pass membrane protein (Potential)

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the rseA family

Homologues:

Organism=Escherichia coli, GI1788925, Length=216, Percent_Identity=100, Blast_Score=441, Evalue=1e-125,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): RSEA_ECOL6 (P0AFX8)

Other databases:

- EMBL:   AE014075
- RefSeq:   NP_754977.1
- PDB:   1YFN
- PDBsum:   1YFN
- ProteinModelPortal:   P0AFX8
- EnsemblBacteria:   EBESCT00000042017
- GeneID:   1038802
- GenomeReviews:   AE014075_GR
- KEGG:   ecc:c3096
- GeneTree:   EBGT00050000010559
- HOGENOM:   HBG391416
- OMA:   QNQSYTN
- ProtClustDB:   PRK10863
- InterPro:   IPR005573
- InterPro:   IPR005572

Pfam domain/function: PF03873 RseA_C; PF03872 RseA_N; SSF89069 Anti-sigma_E_RseA_N

EC number: NA

Molecular weight: Translated: 24322; Mature: 24322

Theoretical pI: Translated: 4.89; Mature: 4.89

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

HASH(0x4068d02c)-;

Cys/Met content:

0.5 %Cys     (Translated Protein)
4.6 %Met     (Translated Protein)
5.1 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
4.6 %Met     (Mature Protein)
5.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQKEQLSALMDGETLDSELLNELAHNPEMQKTWESYHLIRDSMRGDTPEVLHFDISSRVM
CCHHHHHHHHCCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCCCCEEEECHHHHHH
AAIEEEPVRQPATLIPEAQPAPHQWQKMPFWQKVRPWAAQLTQMGVAACVSLAVIVGVQH
HHHHHHHCCCCHHHCCCCCCCCHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
YNGQSETSQQPETPVFNTLPMMGKASPVSLGVPSEATANNGQQQQVQEQRRRINAMLQDY
CCCCCCCCCCCCCCCHHCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHH
ELQRRLHSEQLQFEQAQTQQAAVQVPGIQTLGTQSQ
HHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCH
>Mature Secondary Structure
MQKEQLSALMDGETLDSELLNELAHNPEMQKTWESYHLIRDSMRGDTPEVLHFDISSRVM
CCHHHHHHHHCCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCCCCEEEECHHHHHH
AAIEEEPVRQPATLIPEAQPAPHQWQKMPFWQKVRPWAAQLTQMGVAACVSLAVIVGVQH
HHHHHHHCCCCHHHCCCCCCCCHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
YNGQSETSQQPETPVFNTLPMMGKASPVSLGVPSEATANNGQQQQVQEQRRRINAMLQDY
CCCCCCCCCCCCCCCHHCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHH
ELQRRLHSEQLQFEQAQTQQAAVQVPGIQTLGTQSQ
HHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCH

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 12471157