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The map label for this gene is putA [H]

Identifier: 82544506

GI number: 82544506

Start: 2011959

End: 2015921

Strand: Direct

Name: putA [H]

Synonym: SBO_2043

Alternate gene names: 82544506

Gene position: 2011959-2015921 (Clockwise)

Preceding gene: 82544496

Following gene: 82544508

Centisome position: 44.51

GC content: 56.45

Gene sequence:

>3963_bases
ATGGGAACCACCACCATGGGGGTTAAGCTGGACGACGCGACGCGTGAGCGTATTAAGTCTGCCGCGACACGTATCGATCG
CACGCCACACTGGTTAATTAAGCAGGCGATTTTTTCTTATCTCGAACAACTGGAAAACAGCGATACTCTGCCAGAGCTAC
CTGCGCTGCTTTCTGGTGCTGCCAATGAGAGCGATGAAGCACCGACTCCGGCAGAGGAACCACACCAGCCATTCCTCGAC
TTTGCCGAGCAAATTTTGCCCCAGTCGGTTTCCCGCGCCGCGATCACCGCGGCCTATCGTCGCCCGGAAACCGAAGCGGT
TTCTATGCTGCTGGAACAAGCCCGCCTGCCGCAGCCAGTTGCTGAACAGGCGCATAAACTGGCATATCAACTGGCCGATA
AACTGCGTAATCAAAAAAATGCCAGTGGTCGCGCAGGTATGGTCCAAGGGTTATTGCAGGAGTTTTCGCTGTCATCGCAG
GAAGGCGTGGCGCTGATGTGTCTGGCGGAAGCGTTGTTGCGTATTCCCGACAAAGCCACCCGCGACGCGTTAATTCGCGA
CAAAATCAGCAACTGTAACTGGCAGTCACACATTGGTCGTAGCCCGTCACTGTTTGTTAATGCCGCTACCTGGGGGCTGT
TGTTTACTGGCAAACTGGTTTCCACCCATAACGAAGCCAGCCTCTCCCGCTCGCTGAACCGCATTATCGGTAAAAGCGGT
GAACCGCTGATCCGCAAAGGTGTGGATATGGCGATGCGCCTGATGGGCGAGCAGTTCGTCACGGGTGAAACCATCGCGGA
AGCGTTAGCCAATGCCCGCAAGCTGGAAGAGAAAGGTTTCCGTTACTCTTACGATATGCTGGGCGAAGCTGCACTGACTG
CCGCAGACGCACAGGCGTATATGGTTTCCTATCAGCAGGCGATTCACGCCATTGGTAAAGCGTCTAACGGTCGTGGCATC
TATGAAGGTCCGGGCATTTCAATCAAGCTGTCGGCGCTGCATCCGCGCTACAGCCGCGCCCAGTATGACCGGGTAATGGA
AGAGCTTTACCCGCGTCTGAAATCACTCACCCTGCTGGCGCGTCAGTATGATATTGGTATTAACATCGATGCCGAAGAGG
CCGATCGTCTGGAGATCTCCCTCGATCTGCTGGAAAATCTCTGTTTCGAGCCGGAACTGGCAGGCTGGAACGGCATCGGT
TTTGTTATTCAGGCTTATCAAAAACGCTGCCCGTTGGTGATCGATTACCTGGTTGATCTCGCCACCCGCAGCCGTCGCCG
TCTGATGATTCGCCTGGTGAAAGGCGCGTACTGGGATAGTGAAATCAAGCGTGCGCAGATGGACGGCCTTGAAGGCTATC
CGGTTTATACCCGCAAGGTGTATACCGACGTTTCTTATCTCGCCTGTGCGAAAAAGCTGCTGGCGGTGCCGAATCTAATC
TACCCGCAGTTCGCGACGCACAACGCCCATACGCTGGCAGCGATTTATCAACTGGCAGGTCAGAACTACTATCCGGGTCA
GTACGAGTTCCAGTGCCTGCATGGTATGGGCGAGCCACTGTACGAGCAGGTCACAGGGAAAGTTGCCGACGGTAAACTTA
ACCGACCGTGTCGTATTTATGCCCCGGTTGGCACATATGAAACGCTGCTGGCGTATCTGGTGCGTCGCCTGCTGGAAAAC
GGTGCTAACACCTCGTTTGTTAACCGTATTGCCGACACCTCTTTGCCACTGGATGAACTGGTCGCCGATCCGGTCACTGC
TGTAGAAAAACTGGCGCAACAGGAAGGGCAAACTGGATTACCGCATCCGAAAATTCCCCTGCCGCGCGATCTTTACGGTC
ACGGGCGCGACAACTCGGCAGGGCTGGATCTCGCTAACGAACACCGTCTGGCCTCGCTCTCCTCTGCCCTGCTCAATAGT
GCACTGCAAAAATGGCAGGCCTTGCCAATGCTGGAACAACCGGTAGCGGCAGGTGAGATGTCGCCCGTTATTAACCCTGC
GGAACCGAAAGATATTGTGGGCTTTGTGCGTGAAGCCACGCCGCGTGAAGTAGAACAGGCGCTGGAAAGTGCGGTTAATA
ACGCGCCAATCTGGTTTGCCACGCCTCCGGCTGAACGCGCGGCGATTTTGCATCGCGCTGCCGTGCTAATGGAAAGCCAG
ATGCAGCAACTGATTGGTATTCTGGTGCGTGAAGCCGGAAAAACCTTCAGTAACGCTATTGCCGAAGTGCGCGAAGCGGT
CGATTTTCTCCACTACTACGCCGGACAGGTGCGGGATGATTTCGCTAACGAAACCCACCGTCCATTAGGGCCTGTGGTGT
GTATCAGTCCGTGGAACTTCCCGCTGGCTATTTTCACCGGGCAGATCGCTGCCGCACTGGCGGCAGGTAACAGCGTGCTG
GCAAAACCGGCAGAACAAACGCCGCTGATTGCCGCGCAAGGGATCGCCATTTTGCTGGAAGCGGGTGTACCCCCTGGCGT
GGTGCAATTGCTGCCAGGTCAGGGGGAAACCGTGGGCGCGCAACTGACGGGTGATGATCGCGTGCGCGGGGTGATGTTTA
CCGGTTCAACCGAAGTCGCTACGTTACTGCAGTGCAATATCGCCAGCCGCCTGGACGCTCAGGGTCGCCCTATTCCGCTC
ATCGCTGAAACCGGCGGCATGAACGCGATGATTGTCGATTCTTCAGCACTGACCGAACAAGTCGTCGTGGATGTGCTGGC
CTCGGCGTTCGACAGTGCGGGTCAGCGTTGTTCGGCACTGCGCGTGCTGTGCCTGCAAGATGAGATTGCCGACCACACGT
TGAAAATGCTGCGCGGTGCAATGGCCGAATGCCGGATGGGTAATCCGGGTCGCCTGACCACCGATATCGGTCCGGTGATT
GATAGCGAAGCGAAAGCCAATATTGAGCGCCATATTCAGACCATGCGTAGCAAAGGCCGTCCGGTGTTCCAGGCGGTGCG
GGAAAACAGCGAAGATGCCCGTGAATGGCAAAGCGGCACCTTTGTCGCCCCGACGCTGATCGAACTGGATGACTTTGCCG
AATTGCACAAAGAGGTCTTTGGTCCGGTGCTGCATGTGGTGCGTTACAACCGTAACCAGCTACCAGAGCTGATCGAGCAG
ATTAACGCTTCCGGCTATGGTCTGACGCTTGGTGTCCATACGCGTATTGATGAAACCATCGCCCAGGTCACTGGCTCGGC
CCATGTTGGTAACCTGTATGTTAACCGTAATATGGTGGGCGCAGTGGTTGGTGTGCAGCCGTTCGGCGGCGAAGGGTTGT
CCGGTACCGGGCCGAAAGCAGGCGGTCCGCTCTATCTCTACCGTCTGCTGGCGAATCGCCCGGAAAGTGCGCTGGCAGTG
ACGCTCGCGCGTCAGGATGCAGAGTATCCGGTCGATGCACAGTTGAAAGCCGCATTGACTCAGCCGCTAAATGCACTGCG
GGAATGGGCAGCAAATCGTCCAGAATTGCAGGCGTTATGTACGCAATATGGCGAGCTGGCGCAGGCAGGAATACAACGAT
TGCTGCCGGGGCCGACGGGTGAACGCAACACCTGGACGCTGCTGCCGCGTGAGCGCGTGTTGTGTATTGCCGATGATGAG
CAGGATGCGCTGACTCAGCTCGCCGCCGTGCTGGCGGTGGGCAGCCAGGTACTGTGGCCGGATGACGCGCTGCATCGTCA
GCTAGTAAAGGCATTGCCATCGGCAGTCAGCGAACGTATTCAACTGGCGAAAGCGGAAAATATAACCGCTCAACCCTTTG
ATGCGGTGATCTTCCACGGTGATTCGGATCAGCTTCGCGCATTGTGTGAAGCCGTTGCTGCGCGGGATGGAGCAATTGTT
TCGGTGCAGGGTTTTGCCCGTGGCGAAAGCAATATCCTTCTGGAACGGCTGTATATCGAACGTTCGCTGAGTGTGAATAC
CGCTGCCGCTGGCGGTAACGCCAGTTTAATGACGATCGGTTAA

Upstream 100 bases:

>100_bases
CTACGCAGGTCACATTTAACATGGTTGCACAAAGTTGCAACATCATGGATATTTCACGATAACGTTAAGTTGCACCTTTC
AGAACAACAGGAGTAATGGC

Downstream 100 bases:

>100_bases
ACAGGTAGCCGGAGGATGTTACACCCTCCTCCGGCATCTTTAACGTGGTCGAATCCCCTCAATAATAATCCGCTGCACGT
TTTCAACCGTTTGATTGAAA

Product: trifunctional transcriptional regulator/proline dehydrogenase/pyrroline-5-carboxylate dehydrogenase

Products: NA

Alternate protein names: Proline dehydrogenase; Proline oxidase; Delta-1-pyrroline-5-carboxylate dehydrogenase; P5C dehydrogenase [H]

Number of amino acids: Translated: 1320; Mature: 1319

Protein sequence:

>1320_residues
MGTTTMGVKLDDATRERIKSAATRIDRTPHWLIKQAIFSYLEQLENSDTLPELPALLSGAANESDEAPTPAEEPHQPFLD
FAEQILPQSVSRAAITAAYRRPETEAVSMLLEQARLPQPVAEQAHKLAYQLADKLRNQKNASGRAGMVQGLLQEFSLSSQ
EGVALMCLAEALLRIPDKATRDALIRDKISNCNWQSHIGRSPSLFVNAATWGLLFTGKLVSTHNEASLSRSLNRIIGKSG
EPLIRKGVDMAMRLMGEQFVTGETIAEALANARKLEEKGFRYSYDMLGEAALTAADAQAYMVSYQQAIHAIGKASNGRGI
YEGPGISIKLSALHPRYSRAQYDRVMEELYPRLKSLTLLARQYDIGINIDAEEADRLEISLDLLENLCFEPELAGWNGIG
FVIQAYQKRCPLVIDYLVDLATRSRRRLMIRLVKGAYWDSEIKRAQMDGLEGYPVYTRKVYTDVSYLACAKKLLAVPNLI
YPQFATHNAHTLAAIYQLAGQNYYPGQYEFQCLHGMGEPLYEQVTGKVADGKLNRPCRIYAPVGTYETLLAYLVRRLLEN
GANTSFVNRIADTSLPLDELVADPVTAVEKLAQQEGQTGLPHPKIPLPRDLYGHGRDNSAGLDLANEHRLASLSSALLNS
ALQKWQALPMLEQPVAAGEMSPVINPAEPKDIVGFVREATPREVEQALESAVNNAPIWFATPPAERAAILHRAAVLMESQ
MQQLIGILVREAGKTFSNAIAEVREAVDFLHYYAGQVRDDFANETHRPLGPVVCISPWNFPLAIFTGQIAAALAAGNSVL
AKPAEQTPLIAAQGIAILLEAGVPPGVVQLLPGQGETVGAQLTGDDRVRGVMFTGSTEVATLLQCNIASRLDAQGRPIPL
IAETGGMNAMIVDSSALTEQVVVDVLASAFDSAGQRCSALRVLCLQDEIADHTLKMLRGAMAECRMGNPGRLTTDIGPVI
DSEAKANIERHIQTMRSKGRPVFQAVRENSEDAREWQSGTFVAPTLIELDDFAELHKEVFGPVLHVVRYNRNQLPELIEQ
INASGYGLTLGVHTRIDETIAQVTGSAHVGNLYVNRNMVGAVVGVQPFGGEGLSGTGPKAGGPLYLYRLLANRPESALAV
TLARQDAEYPVDAQLKAALTQPLNALREWAANRPELQALCTQYGELAQAGIQRLLPGPTGERNTWTLLPRERVLCIADDE
QDALTQLAAVLAVGSQVLWPDDALHRQLVKALPSAVSERIQLAKAENITAQPFDAVIFHGDSDQLRALCEAVAARDGAIV
SVQGFARGESNILLERLYIERSLSVNTAAAGGNASLMTIG

Sequences:

>Translated_1320_residues
MGTTTMGVKLDDATRERIKSAATRIDRTPHWLIKQAIFSYLEQLENSDTLPELPALLSGAANESDEAPTPAEEPHQPFLD
FAEQILPQSVSRAAITAAYRRPETEAVSMLLEQARLPQPVAEQAHKLAYQLADKLRNQKNASGRAGMVQGLLQEFSLSSQ
EGVALMCLAEALLRIPDKATRDALIRDKISNCNWQSHIGRSPSLFVNAATWGLLFTGKLVSTHNEASLSRSLNRIIGKSG
EPLIRKGVDMAMRLMGEQFVTGETIAEALANARKLEEKGFRYSYDMLGEAALTAADAQAYMVSYQQAIHAIGKASNGRGI
YEGPGISIKLSALHPRYSRAQYDRVMEELYPRLKSLTLLARQYDIGINIDAEEADRLEISLDLLENLCFEPELAGWNGIG
FVIQAYQKRCPLVIDYLVDLATRSRRRLMIRLVKGAYWDSEIKRAQMDGLEGYPVYTRKVYTDVSYLACAKKLLAVPNLI
YPQFATHNAHTLAAIYQLAGQNYYPGQYEFQCLHGMGEPLYEQVTGKVADGKLNRPCRIYAPVGTYETLLAYLVRRLLEN
GANTSFVNRIADTSLPLDELVADPVTAVEKLAQQEGQTGLPHPKIPLPRDLYGHGRDNSAGLDLANEHRLASLSSALLNS
ALQKWQALPMLEQPVAAGEMSPVINPAEPKDIVGFVREATPREVEQALESAVNNAPIWFATPPAERAAILHRAAVLMESQ
MQQLIGILVREAGKTFSNAIAEVREAVDFLHYYAGQVRDDFANETHRPLGPVVCISPWNFPLAIFTGQIAAALAAGNSVL
AKPAEQTPLIAAQGIAILLEAGVPPGVVQLLPGQGETVGAQLTGDDRVRGVMFTGSTEVATLLQCNIASRLDAQGRPIPL
IAETGGMNAMIVDSSALTEQVVVDVLASAFDSAGQRCSALRVLCLQDEIADHTLKMLRGAMAECRMGNPGRLTTDIGPVI
DSEAKANIERHIQTMRSKGRPVFQAVRENSEDAREWQSGTFVAPTLIELDDFAELHKEVFGPVLHVVRYNRNQLPELIEQ
INASGYGLTLGVHTRIDETIAQVTGSAHVGNLYVNRNMVGAVVGVQPFGGEGLSGTGPKAGGPLYLYRLLANRPESALAV
TLARQDAEYPVDAQLKAALTQPLNALREWAANRPELQALCTQYGELAQAGIQRLLPGPTGERNTWTLLPRERVLCIADDE
QDALTQLAAVLAVGSQVLWPDDALHRQLVKALPSAVSERIQLAKAENITAQPFDAVIFHGDSDQLRALCEAVAARDGAIV
SVQGFARGESNILLERLYIERSLSVNTAAAGGNASLMTIG
>Mature_1319_residues
GTTTMGVKLDDATRERIKSAATRIDRTPHWLIKQAIFSYLEQLENSDTLPELPALLSGAANESDEAPTPAEEPHQPFLDF
AEQILPQSVSRAAITAAYRRPETEAVSMLLEQARLPQPVAEQAHKLAYQLADKLRNQKNASGRAGMVQGLLQEFSLSSQE
GVALMCLAEALLRIPDKATRDALIRDKISNCNWQSHIGRSPSLFVNAATWGLLFTGKLVSTHNEASLSRSLNRIIGKSGE
PLIRKGVDMAMRLMGEQFVTGETIAEALANARKLEEKGFRYSYDMLGEAALTAADAQAYMVSYQQAIHAIGKASNGRGIY
EGPGISIKLSALHPRYSRAQYDRVMEELYPRLKSLTLLARQYDIGINIDAEEADRLEISLDLLENLCFEPELAGWNGIGF
VIQAYQKRCPLVIDYLVDLATRSRRRLMIRLVKGAYWDSEIKRAQMDGLEGYPVYTRKVYTDVSYLACAKKLLAVPNLIY
PQFATHNAHTLAAIYQLAGQNYYPGQYEFQCLHGMGEPLYEQVTGKVADGKLNRPCRIYAPVGTYETLLAYLVRRLLENG
ANTSFVNRIADTSLPLDELVADPVTAVEKLAQQEGQTGLPHPKIPLPRDLYGHGRDNSAGLDLANEHRLASLSSALLNSA
LQKWQALPMLEQPVAAGEMSPVINPAEPKDIVGFVREATPREVEQALESAVNNAPIWFATPPAERAAILHRAAVLMESQM
QQLIGILVREAGKTFSNAIAEVREAVDFLHYYAGQVRDDFANETHRPLGPVVCISPWNFPLAIFTGQIAAALAAGNSVLA
KPAEQTPLIAAQGIAILLEAGVPPGVVQLLPGQGETVGAQLTGDDRVRGVMFTGSTEVATLLQCNIASRLDAQGRPIPLI
AETGGMNAMIVDSSALTEQVVVDVLASAFDSAGQRCSALRVLCLQDEIADHTLKMLRGAMAECRMGNPGRLTTDIGPVID
SEAKANIERHIQTMRSKGRPVFQAVRENSEDAREWQSGTFVAPTLIELDDFAELHKEVFGPVLHVVRYNRNQLPELIEQI
NASGYGLTLGVHTRIDETIAQVTGSAHVGNLYVNRNMVGAVVGVQPFGGEGLSGTGPKAGGPLYLYRLLANRPESALAVT
LARQDAEYPVDAQLKAALTQPLNALREWAANRPELQALCTQYGELAQAGIQRLLPGPTGERNTWTLLPRERVLCIADDEQ
DALTQLAAVLAVGSQVLWPDDALHRQLVKALPSAVSERIQLAKAENITAQPFDAVIFHGDSDQLRALCEAVAARDGAIVS
VQGFARGESNILLERLYIERSLSVNTAAAGGNASLMTIG

Specific function: Oxidizes proline to glutamate for use as a carbon and nitrogen source and also function as a transcriptional repressor of the put operon [H]

COG id: COG4230

COG function: function code C; Delta 1-pyrroline-5-carboxylate dehydrogenase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: In the C-terminal section; belongs to the aldehyde dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI25777724, Length=468, Percent_Identity=30.1282051282051, Blast_Score=180, Evalue=8e-45,
Organism=Homo sapiens, GI21361176, Length=466, Percent_Identity=30.9012875536481, Blast_Score=179, Evalue=1e-44,
Organism=Homo sapiens, GI25777736, Length=522, Percent_Identity=29.8850574712644, Blast_Score=177, Evalue=5e-44,
Organism=Homo sapiens, GI25777734, Length=522, Percent_Identity=29.8850574712644, Blast_Score=177, Evalue=5e-44,
Organism=Homo sapiens, GI25777730, Length=489, Percent_Identity=30.0613496932515, Blast_Score=176, Evalue=9e-44,
Organism=Homo sapiens, GI153266822, Length=463, Percent_Identity=29.5896328293737, Blast_Score=176, Evalue=2e-43,
Organism=Homo sapiens, GI238859541, Length=446, Percent_Identity=31.390134529148, Blast_Score=173, Evalue=1e-42,
Organism=Homo sapiens, GI25777728, Length=414, Percent_Identity=30.9178743961353, Blast_Score=166, Evalue=1e-40,
Organism=Homo sapiens, GI25777732, Length=458, Percent_Identity=29.0393013100437, Blast_Score=162, Evalue=2e-39,
Organism=Homo sapiens, GI21614513, Length=425, Percent_Identity=29.1764705882353, Blast_Score=157, Evalue=4e-38,
Organism=Homo sapiens, GI12007648, Length=432, Percent_Identity=29.3981481481481, Blast_Score=153, Evalue=1e-36,
Organism=Homo sapiens, GI4507229, Length=488, Percent_Identity=29.7131147540984, Blast_Score=151, Evalue=4e-36,
Organism=Homo sapiens, GI238814322, Length=427, Percent_Identity=27.1662763466042, Blast_Score=150, Evalue=1e-35,
Organism=Homo sapiens, GI188035924, Length=523, Percent_Identity=27.7246653919694, Blast_Score=146, Evalue=2e-34,
Organism=Homo sapiens, GI310128103, Length=542, Percent_Identity=27.3062730627306, Blast_Score=146, Evalue=2e-34,
Organism=Homo sapiens, GI310128093, Length=542, Percent_Identity=26.9372693726937, Blast_Score=145, Evalue=2e-34,
Organism=Homo sapiens, GI25777721, Length=501, Percent_Identity=29.5409181636727, Blast_Score=145, Evalue=2e-34,
Organism=Homo sapiens, GI115387104, Length=463, Percent_Identity=26.5658747300216, Blast_Score=140, Evalue=1e-32,
Organism=Homo sapiens, GI310128091, Length=390, Percent_Identity=29.2307692307692, Blast_Score=127, Evalue=7e-29,
Organism=Homo sapiens, GI25777726, Length=468, Percent_Identity=26.0683760683761, Blast_Score=125, Evalue=2e-28,
Organism=Homo sapiens, GI11095441, Length=425, Percent_Identity=26.3529411764706, Blast_Score=123, Evalue=1e-27,
Organism=Homo sapiens, GI25952152, Length=241, Percent_Identity=32.3651452282158, Blast_Score=103, Evalue=1e-21,
Organism=Homo sapiens, GI310128087, Length=362, Percent_Identity=28.4530386740331, Blast_Score=103, Evalue=2e-21,
Organism=Homo sapiens, GI310128089, Length=329, Percent_Identity=27.355623100304, Blast_Score=96, Evalue=2e-19,
Organism=Homo sapiens, GI206597441, Length=413, Percent_Identity=25.6658595641646, Blast_Score=96, Evalue=3e-19,
Organism=Homo sapiens, GI206597439, Length=413, Percent_Identity=25.6658595641646, Blast_Score=96, Evalue=3e-19,
Organism=Homo sapiens, GI22907049, Length=413, Percent_Identity=25.6658595641646, Blast_Score=96, Evalue=3e-19,
Organism=Homo sapiens, GI71773324, Length=397, Percent_Identity=26.9521410579345, Blast_Score=94, Evalue=1e-18,
Organism=Homo sapiens, GI4502043, Length=341, Percent_Identity=27.2727272727273, Blast_Score=93, Evalue=1e-18,
Organism=Homo sapiens, GI238814371, Length=341, Percent_Identity=27.2727272727273, Blast_Score=93, Evalue=1e-18,
Organism=Homo sapiens, GI310128095, Length=316, Percent_Identity=28.1645569620253, Blast_Score=90, Evalue=1e-17,
Organism=Homo sapiens, GI310128097, Length=261, Percent_Identity=28.735632183908, Blast_Score=84, Evalue=9e-16,
Organism=Homo sapiens, GI310128101, Length=309, Percent_Identity=26.8608414239482, Blast_Score=83, Evalue=1e-15,
Organism=Homo sapiens, GI310128099, Length=308, Percent_Identity=26.9480519480519, Blast_Score=82, Evalue=2e-15,
Organism=Homo sapiens, GI73695881, Length=343, Percent_Identity=25.9475218658892, Blast_Score=82, Evalue=3e-15,
Organism=Homo sapiens, GI73695879, Length=343, Percent_Identity=25.9475218658892, Blast_Score=82, Evalue=3e-15,
Organism=Homo sapiens, GI73466520, Length=383, Percent_Identity=25.8485639686684, Blast_Score=75, Evalue=4e-13,
Organism=Homo sapiens, GI4557303, Length=383, Percent_Identity=25.8485639686684, Blast_Score=75, Evalue=5e-13,
Organism=Homo sapiens, GI301500698, Length=284, Percent_Identity=25.3521126760563, Blast_Score=70, Evalue=2e-11,
Organism=Escherichia coli, GI1787250, Length=1320, Percent_Identity=99.0909090909091, Blast_Score=2674, Evalue=0.0,
Organism=Escherichia coli, GI1789015, Length=466, Percent_Identity=30.68669527897, Blast_Score=177, Evalue=5e-45,
Organism=Escherichia coli, GI1787715, Length=455, Percent_Identity=31.6483516483516, Blast_Score=167, Evalue=5e-42,
Organism=Escherichia coli, GI1788042, Length=439, Percent_Identity=32.3462414578588, Blast_Score=165, Evalue=2e-41,
Organism=Escherichia coli, GI1787684, Length=461, Percent_Identity=29.0672451193059, Blast_Score=158, Evalue=2e-39,
Organism=Escherichia coli, GI1787558, Length=490, Percent_Identity=28.3673469387755, Blast_Score=154, Evalue=4e-38,
Organism=Escherichia coli, GI1786504, Length=460, Percent_Identity=28.695652173913, Blast_Score=153, Evalue=8e-38,
Organism=Escherichia coli, GI87081896, Length=468, Percent_Identity=28.8461538461538, Blast_Score=141, Evalue=3e-34,
Organism=Escherichia coli, GI87082295, Length=443, Percent_Identity=28.4424379232506, Blast_Score=140, Evalue=4e-34,
Organism=Escherichia coli, GI87081926, Length=448, Percent_Identity=26.5625, Blast_Score=106, Evalue=1e-23,
Organism=Escherichia coli, GI1787653, Length=404, Percent_Identity=22.2772277227723, Blast_Score=69, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI25144435, Length=465, Percent_Identity=30.1075268817204, Blast_Score=172, Evalue=2e-42,
Organism=Caenorhabditis elegans, GI17534447, Length=489, Percent_Identity=28.8343558282209, Blast_Score=167, Evalue=3e-41,
Organism=Caenorhabditis elegans, GI115534176, Length=480, Percent_Identity=29.7916666666667, Blast_Score=164, Evalue=3e-40,
Organism=Caenorhabditis elegans, GI133930964, Length=471, Percent_Identity=28.8747346072187, Blast_Score=164, Evalue=4e-40,
Organism=Caenorhabditis elegans, GI17562198, Length=462, Percent_Identity=29.4372294372294, Blast_Score=160, Evalue=3e-39,
Organism=Caenorhabditis elegans, GI32564736, Length=412, Percent_Identity=30.3398058252427, Blast_Score=159, Evalue=9e-39,
Organism=Caenorhabditis elegans, GI115532534, Length=366, Percent_Identity=31.4207650273224, Blast_Score=154, Evalue=3e-37,
Organism=Caenorhabditis elegans, GI71986308, Length=427, Percent_Identity=28.3372365339578, Blast_Score=142, Evalue=2e-33,
Organism=Caenorhabditis elegans, GI25143874, Length=461, Percent_Identity=28.1995661605206, Blast_Score=141, Evalue=3e-33,
Organism=Caenorhabditis elegans, GI25143876, Length=461, Percent_Identity=27.9826464208243, Blast_Score=140, Evalue=5e-33,
Organism=Caenorhabditis elegans, GI17534119, Length=463, Percent_Identity=27.645788336933, Blast_Score=139, Evalue=8e-33,
Organism=Caenorhabditis elegans, GI17551164, Length=451, Percent_Identity=26.1640798226164, Blast_Score=132, Evalue=1e-30,
Organism=Caenorhabditis elegans, GI32564151, Length=415, Percent_Identity=26.9879518072289, Blast_Score=122, Evalue=1e-27,
Organism=Caenorhabditis elegans, GI71995606, Length=460, Percent_Identity=25.6521739130435, Blast_Score=119, Evalue=1e-26,
Organism=Caenorhabditis elegans, GI71995613, Length=417, Percent_Identity=25.4196642685851, Blast_Score=116, Evalue=8e-26,
Organism=Caenorhabditis elegans, GI17564084, Length=340, Percent_Identity=26.1764705882353, Blast_Score=92, Evalue=1e-18,
Organism=Caenorhabditis elegans, GI71990744, Length=302, Percent_Identity=27.1523178807947, Blast_Score=90, Evalue=7e-18,
Organism=Caenorhabditis elegans, GI25146391, Length=390, Percent_Identity=23.5897435897436, Blast_Score=87, Evalue=5e-17,
Organism=Caenorhabditis elegans, GI25146394, Length=390, Percent_Identity=23.5897435897436, Blast_Score=87, Evalue=7e-17,
Organism=Caenorhabditis elegans, GI32566756, Length=390, Percent_Identity=23.5897435897436, Blast_Score=87, Evalue=8e-17,
Organism=Saccharomyces cerevisiae, GI6321826, Length=541, Percent_Identity=29.7597042513863, Blast_Score=181, Evalue=6e-46,
Organism=Saccharomyces cerevisiae, GI6325196, Length=465, Percent_Identity=30.752688172043, Blast_Score=175, Evalue=5e-44,
Organism=Saccharomyces cerevisiae, GI6324950, Length=461, Percent_Identity=27.765726681128, Blast_Score=167, Evalue=2e-41,
Organism=Saccharomyces cerevisiae, GI6320917, Length=464, Percent_Identity=29.5258620689655, Blast_Score=166, Evalue=3e-41,
Organism=Saccharomyces cerevisiae, GI6323821, Length=476, Percent_Identity=29.4117647058824, Blast_Score=159, Evalue=4e-39,
Organism=Saccharomyces cerevisiae, GI6323822, Length=475, Percent_Identity=28, Blast_Score=154, Evalue=1e-37,
Organism=Saccharomyces cerevisiae, GI6319478, Length=466, Percent_Identity=30.2575107296137, Blast_Score=142, Evalue=4e-34,
Organism=Saccharomyces cerevisiae, GI6321828, Length=375, Percent_Identity=26.6666666666667, Blast_Score=94, Evalue=2e-19,
Organism=Drosophila melanogaster, GI20129399, Length=462, Percent_Identity=30.5194805194805, Blast_Score=173, Evalue=8e-43,
Organism=Drosophila melanogaster, GI24668425, Length=476, Percent_Identity=28.5714285714286, Blast_Score=168, Evalue=2e-41,
Organism=Drosophila melanogaster, GI24668417, Length=476, Percent_Identity=28.5714285714286, Blast_Score=168, Evalue=2e-41,
Organism=Drosophila melanogaster, GI24668413, Length=476, Percent_Identity=28.5714285714286, Blast_Score=168, Evalue=2e-41,
Organism=Drosophila melanogaster, GI24650465, Length=462, Percent_Identity=28.1385281385281, Blast_Score=166, Evalue=8e-41,
Organism=Drosophila melanogaster, GI281362580, Length=452, Percent_Identity=27.6548672566372, Blast_Score=162, Evalue=2e-39,
Organism=Drosophila melanogaster, GI62472918, Length=452, Percent_Identity=27.6548672566372, Blast_Score=162, Evalue=2e-39,
Organism=Drosophila melanogaster, GI62472926, Length=452, Percent_Identity=27.6548672566372, Blast_Score=162, Evalue=2e-39,
Organism=Drosophila melanogaster, GI62472936, Length=452, Percent_Identity=27.6548672566372, Blast_Score=162, Evalue=2e-39,
Organism=Drosophila melanogaster, GI21356737, Length=452, Percent_Identity=27.6548672566372, Blast_Score=162, Evalue=2e-39,
Organism=Drosophila melanogaster, GI24585660, Length=462, Percent_Identity=25.974025974026, Blast_Score=150, Evalue=5e-36,
Organism=Drosophila melanogaster, GI24666674, Length=451, Percent_Identity=29.490022172949, Blast_Score=147, Evalue=5e-35,
Organism=Drosophila melanogaster, GI28571798, Length=451, Percent_Identity=28.6031042128603, Blast_Score=142, Evalue=2e-33,
Organism=Drosophila melanogaster, GI28571796, Length=451, Percent_Identity=28.6031042128603, Blast_Score=142, Evalue=2e-33,
Organism=Drosophila melanogaster, GI28571794, Length=451, Percent_Identity=28.6031042128603, Blast_Score=142, Evalue=2e-33,
Organism=Drosophila melanogaster, GI28571802, Length=451, Percent_Identity=28.6031042128603, Blast_Score=142, Evalue=2e-33,
Organism=Drosophila melanogaster, GI28571800, Length=451, Percent_Identity=28.6031042128603, Blast_Score=142, Evalue=2e-33,
Organism=Drosophila melanogaster, GI28571806, Length=451, Percent_Identity=28.6031042128603, Blast_Score=142, Evalue=2e-33,
Organism=Drosophila melanogaster, GI28574525, Length=498, Percent_Identity=25.9036144578313, Blast_Score=133, Evalue=1e-30,
Organism=Drosophila melanogaster, GI24638876, Length=401, Percent_Identity=27.1820448877805, Blast_Score=103, Evalue=1e-21,
Organism=Drosophila melanogaster, GI24638878, Length=401, Percent_Identity=27.1820448877805, Blast_Score=102, Evalue=2e-21,
Organism=Drosophila melanogaster, GI281360299, Length=341, Percent_Identity=29.3255131964809, Blast_Score=96, Evalue=2e-19,
Organism=Drosophila melanogaster, GI281360297, Length=341, Percent_Identity=29.3255131964809, Blast_Score=96, Evalue=2e-19,
Organism=Drosophila melanogaster, GI281360295, Length=341, Percent_Identity=29.3255131964809, Blast_Score=96, Evalue=2e-19,
Organism=Drosophila melanogaster, GI24586250, Length=341, Percent_Identity=29.3255131964809, Blast_Score=96, Evalue=2e-19,
Organism=Drosophila melanogaster, GI281360301, Length=341, Percent_Identity=29.3255131964809, Blast_Score=95, Evalue=3e-19,
Organism=Drosophila melanogaster, GI45552499, Length=341, Percent_Identity=28.4457478005865, Blast_Score=94, Evalue=5e-19,
Organism=Drosophila melanogaster, GI281360303, Length=341, Percent_Identity=28.4457478005865, Blast_Score=94, Evalue=9e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016161
- InterPro:   IPR016163
- InterPro:   IPR016160
- InterPro:   IPR016162
- InterPro:   IPR015590
- InterPro:   IPR005933
- InterPro:   IPR002872 [H]

Pfam domain/function: PF00171 Aldedh; PF01619 Pro_dh [H]

EC number: =1.5.99.8; =1.5.1.12 [H]

Molecular weight: Translated: 143740; Mature: 143609

Theoretical pI: Translated: 5.48; Mature: 5.48

Prosite motif: PS00687 ALDEHYDE_DEHYDR_GLU ; PS00070 ALDEHYDE_DEHYDR_CYS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGTTTMGVKLDDATRERIKSAATRIDRTPHWLIKQAIFSYLEQLENSDTLPELPALLSGA
CCCCEEEEEECHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCCCCHHHHHHHCCC
ANESDEAPTPAEEPHQPFLDFAEQILPQSVSRAAITAAYRRPETEAVSMLLEQARLPQPV
CCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCHH
AEQAHKLAYQLADKLRNQKNASGRAGMVQGLLQEFSLSSQEGVALMCLAEALLRIPDKAT
HHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHCCCHHH
RDALIRDKISNCNWQSHIGRSPSLFVNAATWGLLFTGKLVSTHNEASLSRSLNRIIGKSG
HHHHHHHHHHCCCCHHHCCCCCCEEEEHHHHHHHEECHHHHCCCHHHHHHHHHHHHCCCC
EPLIRKGVDMAMRLMGEQFVTGETIAEALANARKLEEKGFRYSYDMLGEAALTAADAQAY
CHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCCEEEHHHHHHHHHHHHHHHHH
MVSYQQAIHAIGKASNGRGIYEGPGISIKLSALHPRYSRAQYDRVMEELYPRLKSLTLLA
HHHHHHHHHHHHCCCCCCCCEECCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHH
RQYDIGINIDAEEADRLEISLDLLENLCFEPELAGWNGIGFVIQAYQKRCPLVIDYLVDL
HHHCCCCCCCCCCCCHHEEEHHHHHHCCCCCCCCCCCCHHHHHHHHHHCCCHHHHHHHHH
ATRSRRRLMIRLVKGAYWDSEIKRAQMDGLEGYPVYTRKVYTDVSYLACAKKLLAVPNLI
HHHHHHHHHHHHHHCCCCHHHHHHHHHCCCCCCCEEHHHHHHHHHHHHHHHHHHHCCCHH
YPQFATHNAHTLAAIYQLAGQNYYPGQYEFQCLHGMGEPLYEQVTGKVADGKLNRPCRIY
CCCCCCCCHHHHHHHHHHHCCCCCCCCCHHHHHHCCCCHHHHHHCCCCCCCCCCCCEEEE
APVGTYETLLAYLVRRLLENGANTSFVNRIADTSLPLDELVADPVTAVEKLAQQEGQTGL
ECCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCCHHHHHCCHHHHHHHHHHHCCCCCC
PHPKIPLPRDLYGHGRDNSAGLDLANEHRLASLSSALLNSALQKWQALPMLEQPVAAGEM
CCCCCCCCHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCHHCCCCCCCC
SPVINPAEPKDIVGFVREATPREVEQALESAVNNAPIWFATPPAERAAILHRAAVLMESQ
CCCCCCCCHHHHHHHHHHCCHHHHHHHHHHHHCCCCEEEECCCHHHHHHHHHHHHHHHHH
MQQLIGILVREAGKTFSNAIAEVREAVDFLHYYAGQVRDDFANETHRPLGPVVCISPWNF
HHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEECCCCC
PLAIFTGQIAAALAAGNSVLAKPAEQTPLIAAQGIAILLEAGVPPGVVQLLPGQGETVGA
CHHHHHHHHHHHHHCCCCCCCCCCCCCCCCHHCCCEEEEECCCCCCCEEECCCCCCEEEE
QLTGDDRVRGVMFTGSTEVATLLQCNIASRLDAQGRPIPLIAETGGMNAMIVDSSALTEQ
EECCCCCEEEEEEECCHHHHHHHHHHHHHHCCCCCCCEEEEECCCCCEEEEECCHHHHHH
VVVDVLASAFDSAGQRCSALRVLCLQDEIADHTLKMLRGAMAECRMGNPGRLTTDIGPVI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEECCCCCCC
DSEAKANIERHIQTMRSKGRPVFQAVRENSEDAREWQSGTFVAPTLIELDDFAELHKEVF
CCHHHHHHHHHHHHHHHCCCHHHHHHHCCCHHHHHHCCCCEECCHHHHHHHHHHHHHHHH
GPVLHVVRYNRNQLPELIEQINASGYGLTLGVHTRIDETIAQVTGSAHVGNLYVNRNMVG
HHHHHHHHCCHHHHHHHHHHHCCCCCEEEEEEHHHHHHHHHHHCCCCEECEEEECCCCEE
AVVGVQPFGGEGLSGTGPKAGGPLYLYRLLANRPESALAVTLARQDAEYPVDAQLKAALT
EEEECCCCCCCCCCCCCCCCCCHHHHHHHHHCCCCHHEEEEEECCCCCCCCCHHHHHHHH
QPLNALREWAANRPELQALCTQYGELAQAGIQRLLPGPTGERNTWTLLPRERVLCIADDE
HHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEECCCCCEEEEECCC
QDALTQLAAVLAVGSQVLWPDDALHRQLVKALPSAVSERIQLAKAENITAQPFDAVIFHG
HHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEEC
DSDQLRALCEAVAARDGAIVSVQGFARGESNILLERLYIERSLSVNTAAAGGNASLMTIG
CHHHHHHHHHHHHHCCCCEEEEECCCCCCHHHHHHHHHHHHCCCCEEECCCCCCEEEEEC
>Mature Secondary Structure 
GTTTMGVKLDDATRERIKSAATRIDRTPHWLIKQAIFSYLEQLENSDTLPELPALLSGA
CCCEEEEEECHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCCCCHHHHHHHCCC
ANESDEAPTPAEEPHQPFLDFAEQILPQSVSRAAITAAYRRPETEAVSMLLEQARLPQPV
CCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCHH
AEQAHKLAYQLADKLRNQKNASGRAGMVQGLLQEFSLSSQEGVALMCLAEALLRIPDKAT
HHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHCCCHHH
RDALIRDKISNCNWQSHIGRSPSLFVNAATWGLLFTGKLVSTHNEASLSRSLNRIIGKSG
HHHHHHHHHHCCCCHHHCCCCCCEEEEHHHHHHHEECHHHHCCCHHHHHHHHHHHHCCCC
EPLIRKGVDMAMRLMGEQFVTGETIAEALANARKLEEKGFRYSYDMLGEAALTAADAQAY
CHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCCEEEHHHHHHHHHHHHHHHHH
MVSYQQAIHAIGKASNGRGIYEGPGISIKLSALHPRYSRAQYDRVMEELYPRLKSLTLLA
HHHHHHHHHHHHCCCCCCCCEECCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHH
RQYDIGINIDAEEADRLEISLDLLENLCFEPELAGWNGIGFVIQAYQKRCPLVIDYLVDL
HHHCCCCCCCCCCCCHHEEEHHHHHHCCCCCCCCCCCCHHHHHHHHHHCCCHHHHHHHHH
ATRSRRRLMIRLVKGAYWDSEIKRAQMDGLEGYPVYTRKVYTDVSYLACAKKLLAVPNLI
HHHHHHHHHHHHHHCCCCHHHHHHHHHCCCCCCCEEHHHHHHHHHHHHHHHHHHHCCCHH
YPQFATHNAHTLAAIYQLAGQNYYPGQYEFQCLHGMGEPLYEQVTGKVADGKLNRPCRIY
CCCCCCCCHHHHHHHHHHHCCCCCCCCCHHHHHHCCCCHHHHHHCCCCCCCCCCCCEEEE
APVGTYETLLAYLVRRLLENGANTSFVNRIADTSLPLDELVADPVTAVEKLAQQEGQTGL
ECCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCCHHHHHCCHHHHHHHHHHHCCCCCC
PHPKIPLPRDLYGHGRDNSAGLDLANEHRLASLSSALLNSALQKWQALPMLEQPVAAGEM
CCCCCCCCHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCHHCCCCCCCC
SPVINPAEPKDIVGFVREATPREVEQALESAVNNAPIWFATPPAERAAILHRAAVLMESQ
CCCCCCCCHHHHHHHHHHCCHHHHHHHHHHHHCCCCEEEECCCHHHHHHHHHHHHHHHHH
MQQLIGILVREAGKTFSNAIAEVREAVDFLHYYAGQVRDDFANETHRPLGPVVCISPWNF
HHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEECCCCC
PLAIFTGQIAAALAAGNSVLAKPAEQTPLIAAQGIAILLEAGVPPGVVQLLPGQGETVGA
CHHHHHHHHHHHHHCCCCCCCCCCCCCCCCHHCCCEEEEECCCCCCCEEECCCCCCEEEE
QLTGDDRVRGVMFTGSTEVATLLQCNIASRLDAQGRPIPLIAETGGMNAMIVDSSALTEQ
EECCCCCEEEEEEECCHHHHHHHHHHHHHHCCCCCCCEEEEECCCCCEEEEECCHHHHHH
VVVDVLASAFDSAGQRCSALRVLCLQDEIADHTLKMLRGAMAECRMGNPGRLTTDIGPVI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEECCCCCCC
DSEAKANIERHIQTMRSKGRPVFQAVRENSEDAREWQSGTFVAPTLIELDDFAELHKEVF
CCHHHHHHHHHHHHHHHCCCHHHHHHHCCCHHHHHHCCCCEECCHHHHHHHHHHHHHHHH
GPVLHVVRYNRNQLPELIEQINASGYGLTLGVHTRIDETIAQVTGSAHVGNLYVNRNMVG
HHHHHHHHCCHHHHHHHHHHHCCCCCEEEEEEHHHHHHHHHHHCCCCEECEEEECCCCEE
AVVGVQPFGGEGLSGTGPKAGGPLYLYRLLANRPESALAVTLARQDAEYPVDAQLKAALT
EEEECCCCCCCCCCCCCCCCCCHHHHHHHHHCCCCHHEEEEEECCCCCCCCCHHHHHHHH
QPLNALREWAANRPELQALCTQYGELAQAGIQRLLPGPTGERNTWTLLPRERVLCIADDE
HHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEECCCCCEEEEECCC
QDALTQLAAVLAVGSQVLWPDDALHRQLVKALPSAVSERIQLAKAENITAQPFDAVIFHG
HHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEEC
DSDQLRALCEAVAARDGAIVSVQGFARGESNILLERLYIERSLSVNTAAAGGNASLMTIG
CHHHHHHHHHHHHHCCCCEEEEECCCCCCHHHHHHHHHHHHCCCCEEECCCCCCEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7966312; 8905232; 9278503; 3325781; 12514740 [H]