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The map label for this gene is sapD [H]

Identifier: 82544252

GI number: 82544252

Start: 1748695

End: 1749687

Strand: Direct

Name: sapD [H]

Synonym: SBO_1771

Alternate gene names: 82544252

Gene position: 1748695-1749687 (Clockwise)

Preceding gene: 82544251

Following gene: 82544253

Centisome position: 38.69

GC content: 51.16

Gene sequence:

>993_bases
ATGCCATTACTCGATATTCGTAACCTGACCATTGAATTTAAAACCGGTGATGAGTGGGTTAAAGCCGTCGACCGGGTAAG
TATGACCTTAACCGAAGGTGAAATCCGCGGTCTTGTTGGTGAATCCGGTTCCGGCAAGAGTTTGATTGCGAAAGCGATTT
GTGGGGTGAATAAAGATAACTGGCGTGTTATTGCTGACCGTATGCGTTTTGATGATATCGATTTGCTGCGTCTCTCCGCA
CGCGAACGGCGCAAACTGGTTGGCCATAACGTGTCGATGATTTTCCAGGAACCGCAGTCGTGTCTTGACCCTTCAGAACG
TGTGGGTCGCCAGTTGATGCAAAACATCCCAGCCTGGACCTATAAAGGCCGTTGGTGGCAGCGTTTTGGCTGGCGCAAAC
GCCGTGCCATTGAACTGCTGCACCGCGTGGGGATTAAAGATCACAAAGATGCGATGCGCAGTTTTCCCTATGAGTTGACC
GAAGGTGAATGTCAGAAAGTGATGATAGCCATTGCACTGGCGAATCAACCGCGTCTGCTGATTGCTGACGAACCGACCAA
CTCAATGGAGCCAACAACCCAGGCGCAAATCTTTCGCCTGCTGACGCGTCTCAACCAAAACAGCAATACCACTATTTTGC
TTATCAGCCATGACTTACAAATGCTTAGCCAATGGGCGGATAAAATTAACGTGCTTTACTGCGGTCAAACAGTGGAAACC
GCGCCGAGTAAGGAGTTGGTGACGATGCCACATCATCCTTATACCCAGGCGCTGATCCGCGCGATACCAGACTTCGGCAG
CGCGATGCCGCATAAAAGTCGCCTCAATACGCTGCCCGGCGCTATCCCACTGCTGGAACAGTTACCGATTGGTTGTCGTC
TGGGGCCACGTTGCCCGTATGCACAACGAGAATGCATTGTGACGCCACGTTTGACGGGGGCGAAAAATCATCTCTATGCC
TGTCATTTCCCGCTGAACATGGAGAAAGAGTGA

Upstream 100 bases:

>100_bases
GGACTGTCATGCTGCCAGGTGCGGCAATTATGATTAGCGTGTTGTTGGTTAACCTCCTTGGCGATGGCGTTCGTCGTGCG
ATTATTGCGGGGGTGGAATA

Downstream 100 bases:

>100_bases
GATGATCGAAACGCTGCTTGAAGTGCGTAATTTAAGTAAAACGTTCCGCTACCGGACCGGCTGGTTTCGCCGTCAGACCG
TAGAAGCGGTAAAACCCTTG

Product: ATP-binding protein of peptide transport system

Products: ADP; phosphate; peptides [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 330; Mature: 329

Protein sequence:

>330_residues
MPLLDIRNLTIEFKTGDEWVKAVDRVSMTLTEGEIRGLVGESGSGKSLIAKAICGVNKDNWRVIADRMRFDDIDLLRLSA
RERRKLVGHNVSMIFQEPQSCLDPSERVGRQLMQNIPAWTYKGRWWQRFGWRKRRAIELLHRVGIKDHKDAMRSFPYELT
EGECQKVMIAIALANQPRLLIADEPTNSMEPTTQAQIFRLLTRLNQNSNTTILLISHDLQMLSQWADKINVLYCGQTVET
APSKELVTMPHHPYTQALIRAIPDFGSAMPHKSRLNTLPGAIPLLEQLPIGCRLGPRCPYAQRECIVTPRLTGAKNHLYA
CHFPLNMEKE

Sequences:

>Translated_330_residues
MPLLDIRNLTIEFKTGDEWVKAVDRVSMTLTEGEIRGLVGESGSGKSLIAKAICGVNKDNWRVIADRMRFDDIDLLRLSA
RERRKLVGHNVSMIFQEPQSCLDPSERVGRQLMQNIPAWTYKGRWWQRFGWRKRRAIELLHRVGIKDHKDAMRSFPYELT
EGECQKVMIAIALANQPRLLIADEPTNSMEPTTQAQIFRLLTRLNQNSNTTILLISHDLQMLSQWADKINVLYCGQTVET
APSKELVTMPHHPYTQALIRAIPDFGSAMPHKSRLNTLPGAIPLLEQLPIGCRLGPRCPYAQRECIVTPRLTGAKNHLYA
CHFPLNMEKE
>Mature_329_residues
PLLDIRNLTIEFKTGDEWVKAVDRVSMTLTEGEIRGLVGESGSGKSLIAKAICGVNKDNWRVIADRMRFDDIDLLRLSAR
ERRKLVGHNVSMIFQEPQSCLDPSERVGRQLMQNIPAWTYKGRWWQRFGWRKRRAIELLHRVGIKDHKDAMRSFPYELTE
GECQKVMIAIALANQPRLLIADEPTNSMEPTTQAQIFRLLTRLNQNSNTTILLISHDLQMLSQWADKINVLYCGQTVETA
PSKELVTMPHHPYTQALIRAIPDFGSAMPHKSRLNTLPGAIPLLEQLPIGCRLGPRCPYAQRECIVTPRLTGAKNHLYAC
HFPLNMEKE

Specific function: Involved in a peptide intake transport system that plays a role in the resistance to antimicrobial peptides [H]

COG id: COG4170

COG function: function code V; ABC-type antimicrobial peptide transport system, ATPase component

Gene ontology:

Cell location: Cell inner membrane; Peripheral membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transporter domain [H]

Homologues:

Organism=Escherichia coli, GI1787548, Length=330, Percent_Identity=99.6969696969697, Blast_Score=686, Evalue=0.0,
Organism=Escherichia coli, GI1789963, Length=328, Percent_Identity=43.9024390243902, Blast_Score=271, Evalue=5e-74,
Organism=Escherichia coli, GI1787759, Length=328, Percent_Identity=37.5, Blast_Score=210, Evalue=1e-55,
Organism=Escherichia coli, GI48994883, Length=324, Percent_Identity=37.3456790123457, Blast_Score=207, Evalue=5e-55,
Organism=Escherichia coli, GI1787500, Length=329, Percent_Identity=33.7386018237082, Blast_Score=171, Evalue=9e-44,
Organism=Escherichia coli, GI145693107, Length=271, Percent_Identity=33.9483394833948, Blast_Score=164, Evalue=9e-42,
Organism=Escherichia coli, GI1788506, Length=269, Percent_Identity=35.6877323420074, Blast_Score=154, Evalue=9e-39,
Organism=Escherichia coli, GI1787758, Length=316, Percent_Identity=31.0126582278481, Blast_Score=147, Evalue=1e-36,
Organism=Escherichia coli, GI1789962, Length=307, Percent_Identity=29.6416938110749, Blast_Score=138, Evalue=4e-34,
Organism=Escherichia coli, GI1787547, Length=275, Percent_Identity=28, Blast_Score=111, Evalue=7e-26,
Organism=Escherichia coli, GI1786398, Length=290, Percent_Identity=28.9655172413793, Blast_Score=109, Evalue=2e-25,
Organism=Escherichia coli, GI48994997, Length=263, Percent_Identity=28.8973384030418, Blast_Score=108, Evalue=4e-25,
Organism=Escherichia coli, GI1789890, Length=241, Percent_Identity=28.6307053941909, Blast_Score=104, Evalue=7e-24,
Organism=Escherichia coli, GI1789891, Length=254, Percent_Identity=30.3149606299213, Blast_Score=102, Evalue=2e-23,
Organism=Escherichia coli, GI87081834, Length=230, Percent_Identity=30.8695652173913, Blast_Score=99, Evalue=4e-22,
Organism=Escherichia coli, GI1787105, Length=253, Percent_Identity=29.6442687747036, Blast_Score=92, Evalue=3e-20,
Organism=Escherichia coli, GI1789873, Length=221, Percent_Identity=30.316742081448, Blast_Score=92, Evalue=6e-20,
Organism=Escherichia coli, GI1789032, Length=248, Percent_Identity=26.6129032258064, Blast_Score=91, Evalue=1e-19,
Organism=Escherichia coli, GI87081791, Length=270, Percent_Identity=26.2962962962963, Blast_Score=85, Evalue=7e-18,
Organism=Escherichia coli, GI1788225, Length=262, Percent_Identity=25.9541984732824, Blast_Score=80, Evalue=2e-16,
Organism=Escherichia coli, GI1788450, Length=239, Percent_Identity=25.5230125523013, Blast_Score=79, Evalue=3e-16,
Organism=Escherichia coli, GI1786703, Length=241, Percent_Identity=27.8008298755187, Blast_Score=79, Evalue=3e-16,
Organism=Escherichia coli, GI1790544, Length=240, Percent_Identity=28.3333333333333, Blast_Score=79, Evalue=5e-16,
Organism=Escherichia coli, GI1787712, Length=263, Percent_Identity=25.0950570342205, Blast_Score=79, Evalue=5e-16,
Organism=Escherichia coli, GI1789672, Length=266, Percent_Identity=26.3157894736842, Blast_Score=76, Evalue=3e-15,
Organism=Escherichia coli, GI1787029, Length=244, Percent_Identity=23.7704918032787, Blast_Score=75, Evalue=5e-15,
Organism=Escherichia coli, GI1787792, Length=245, Percent_Identity=30.2040816326531, Blast_Score=75, Evalue=8e-15,
Organism=Escherichia coli, GI1790162, Length=260, Percent_Identity=22.6923076923077, Blast_Score=73, Evalue=3e-14,
Organism=Escherichia coli, GI1786872, Length=214, Percent_Identity=26.6355140186916, Blast_Score=72, Evalue=5e-14,
Organism=Escherichia coli, GI48995001, Length=241, Percent_Identity=29.4605809128631, Blast_Score=72, Evalue=6e-14,
Organism=Escherichia coli, GI1787370, Length=255, Percent_Identity=24.3137254901961, Blast_Score=70, Evalue=2e-13,
Organism=Escherichia coli, GI1789864, Length=251, Percent_Identity=25.0996015936255, Blast_Score=69, Evalue=6e-13,
Organism=Escherichia coli, GI1788644, Length=129, Percent_Identity=27.1317829457364, Blast_Score=68, Evalue=7e-13,
Organism=Escherichia coli, GI1787089, Length=219, Percent_Identity=26.027397260274, Blast_Score=68, Evalue=1e-12,
Organism=Escherichia coli, GI1788472, Length=229, Percent_Identity=28.82096069869, Blast_Score=66, Evalue=4e-12,
Organism=Escherichia coli, GI1788210, Length=266, Percent_Identity=26.3157894736842, Blast_Score=64, Evalue=1e-11,
Organism=Escherichia coli, GI87082267, Length=248, Percent_Identity=22.5806451612903, Blast_Score=62, Evalue=6e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003439
- InterPro:   IPR003593
- InterPro:   IPR010066
- InterPro:   IPR013563 [H]

Pfam domain/function: PF00005 ABC_tran; PF08352 oligo_HPY [H]

EC number: NA

Molecular weight: Translated: 37673; Mature: 37542

Theoretical pI: Translated: 9.29; Mature: 9.29

Prosite motif: PS50893 ABC_TRANSPORTER_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.4 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
6.1 %Cys+Met (Translated Protein)
2.4 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
5.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPLLDIRNLTIEFKTGDEWVKAVDRVSMTLTEGEIRGLVGESGSGKSLIAKAICGVNKDN
CCCEEEECEEEEEECCHHHHHHHHHHHEEEECCHHHHCCCCCCCCHHHHHHHHHCCCCCC
WRVIADRMRFDDIDLLRLSARERRKLVGHNVSMIFQEPQSCLDPSERVGRQLMQNIPAWT
CEEEEEHHCCCCHHHHHHHHHHHHHHHCCCHHHEEECCHHHCCHHHHHHHHHHHHCCCCE
YKGRWWQRFGWRKRRAIELLHRVGIKDHKDAMRSFPYELTEGECQKVMIAIALANQPRLL
ECCCHHHHHCHHHHHHHHHHHHCCCCCHHHHHHHCCCCCCCCHHHEEEEEEEECCCCEEE
IADEPTNSMEPTTQAQIFRLLTRLNQNSNTTILLISHDLQMLSQWADKINVLYCGQTVET
EEECCCCCCCCHHHHHHHHHHHHHCCCCCCEEEEEECCHHHHHHHHHHCEEEEECCCCCC
APSKELVTMPHHPYTQALIRAIPDFGSAMPHKSRLNTLPGAIPLLEQLPIGCRLGPRCPY
CCCCCEEECCCCHHHHHHHHHCCHHCCCCCCHHHHHCCCCCHHHHHHCCCCCCCCCCCCC
AQRECIVTPRLTGAKNHLYACHFPLNMEKE
CCCCEEECCCCCCCCCCEEEEECCCCCCCC
>Mature Secondary Structure 
PLLDIRNLTIEFKTGDEWVKAVDRVSMTLTEGEIRGLVGESGSGKSLIAKAICGVNKDN
CCEEEECEEEEEECCHHHHHHHHHHHEEEECCHHHHCCCCCCCCHHHHHHHHHCCCCCC
WRVIADRMRFDDIDLLRLSARERRKLVGHNVSMIFQEPQSCLDPSERVGRQLMQNIPAWT
CEEEEEHHCCCCHHHHHHHHHHHHHHHCCCHHHEEECCHHHCCHHHHHHHHHHHHCCCCE
YKGRWWQRFGWRKRRAIELLHRVGIKDHKDAMRSFPYELTEGECQKVMIAIALANQPRLL
ECCCHHHHHCHHHHHHHHHHHHCCCCCHHHHHHHCCCCCCCCHHHEEEEEEEECCCCEEE
IADEPTNSMEPTTQAQIFRLLTRLNQNSNTTILLISHDLQMLSQWADKINVLYCGQTVET
EEECCCCCCCCHHHHHHHHHHHHHCCCCCCEEEEEECCHHHHHHHHHHCEEEEECCCCCC
APSKELVTMPHHPYTQALIRAIPDFGSAMPHKSRLNTLPGAIPLLEQLPIGCRLGPRCPY
CCCCCEEECCCCHHHHHHHHHCCHHCCCCCCHHHHHCCCCCHHHHHHCCCCCCCCCCCCC
AQRECIVTPRLTGAKNHLYACHFPLNMEKE
CCCCEEECCCCCCCCCCEEEEECCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; peptides [Periplasm]; H2O [C]

Specific reaction: ATP + peptides [Periplasm] + H2O = ADP + phosphate + peptides [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]