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The map label for this gene is yeaE [H]

Identifier: 82543820

GI number: 82543820

Start: 1297647

End: 1298501

Strand: Direct

Name: yeaE [H]

Synonym: SBO_1312

Alternate gene names: 82543820

Gene position: 1297647-1298501 (Clockwise)

Preceding gene: 82543819

Following gene: 82543822

Centisome position: 28.71

GC content: 50.29

Gene sequence:

>855_bases
ATGCAACAAAAAATGATTCAATTTAGTGGCGATGTCTCACTGCCAGCCATAGGGCAGGGAACATGGTATATGGGCGAAGA
TGCCAGTCAGCGCAAAACAGAAGTTGCTGCACTACGCGCGGGCATTGAGCTCGGTTTAACCCTCATTGATACCGCCGAAA
TGTATGCCGATGGCGGTGCCGAAAAGGTGGTTGGGGAAGCATTAACCGGTCTGCGTGATAACGTCTTTCTCGTCTCTAAA
GTCTATCCGTGGAATGCTGGCAGGCAAAAAGCGATAAATGCATGCGAAGCCAGTTTACGCCGTCTCAATACTGATTATCT
CGATCTCTACTTATTACACTGGTCTGGCAGTTTCGCTTTTGAAGAGACTGTTGCAGCGATGGAAAAATTGATCGCCCAGG
GAAAAATCCGCCGCTGGGGCGTTTCTAACCTTGATTATGCTGATATGCAGGAACTCTGGCAGCTGCCGGGGGGAAATCAG
TGTGCCACTAATCAGGTGCTTTACCATCTCGGTTCACGAGGGATTGAGTACGATCTACTCCCCTGGTGCCAGCAACAGCA
GATGCCGGTGATGGCTTACAGTCCATTAGCCCAGGCCGGGCGGTTGCGCAATGGACTGTTAAAAAACGCGGTAGTCAACG
AAATTGCACATGCTCACAATATCAGCTCGGCACAAGTATTGTTGGCGAGGGTAATCAGCCATCAGGGTGTGATGGCGATT
CCAAAAGCGGCCACGATTGCCCATGTTCAACAGAATGCGGCTGTGCTTGAGGTCGAACTTTCGTCAGCGGAATTAACCAT
GCTGGATAAAGCGTATCCGGCACCAAAAGGAAAAACTGCGCTGGATATGGTGTGA

Upstream 100 bases:

>100_bases
ACAAATTCTGATAATGCATCTTTCCAGGGCATTTTGTGCATAAAAACAGGGCGTCACGCCCTGTTTTGCATTACGGTGGT
GCAATACCTGGGAGGAAACA

Downstream 100 bases:

>100_bases
TGTTGATACGTGCCGGATGCATCGCACCCGGCACACAACATTAACGCAAATTAACGTTTCGCAACGCGAATGGATTGCGC
CAGATGTGCAGGTTTCTCTT

Product: aldehyde reductase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 284; Mature: 284

Protein sequence:

>284_residues
MQQKMIQFSGDVSLPAIGQGTWYMGEDASQRKTEVAALRAGIELGLTLIDTAEMYADGGAEKVVGEALTGLRDNVFLVSK
VYPWNAGRQKAINACEASLRRLNTDYLDLYLLHWSGSFAFEETVAAMEKLIAQGKIRRWGVSNLDYADMQELWQLPGGNQ
CATNQVLYHLGSRGIEYDLLPWCQQQQMPVMAYSPLAQAGRLRNGLLKNAVVNEIAHAHNISSAQVLLARVISHQGVMAI
PKAATIAHVQQNAAVLEVELSSAELTMLDKAYPAPKGKTALDMV

Sequences:

>Translated_284_residues
MQQKMIQFSGDVSLPAIGQGTWYMGEDASQRKTEVAALRAGIELGLTLIDTAEMYADGGAEKVVGEALTGLRDNVFLVSK
VYPWNAGRQKAINACEASLRRLNTDYLDLYLLHWSGSFAFEETVAAMEKLIAQGKIRRWGVSNLDYADMQELWQLPGGNQ
CATNQVLYHLGSRGIEYDLLPWCQQQQMPVMAYSPLAQAGRLRNGLLKNAVVNEIAHAHNISSAQVLLARVISHQGVMAI
PKAATIAHVQQNAAVLEVELSSAELTMLDKAYPAPKGKTALDMV
>Mature_284_residues
MQQKMIQFSGDVSLPAIGQGTWYMGEDASQRKTEVAALRAGIELGLTLIDTAEMYADGGAEKVVGEALTGLRDNVFLVSK
VYPWNAGRQKAINACEASLRRLNTDYLDLYLLHWSGSFAFEETVAAMEKLIAQGKIRRWGVSNLDYADMQELWQLPGGNQ
CATNQVLYHLGSRGIEYDLLPWCQQQQMPVMAYSPLAQAGRLRNGLLKNAVVNEIAHAHNISSAQVLLARVISHQGVMAI
PKAATIAHVQQNAAVLEVELSSAELTMLDKAYPAPKGKTALDMV

Specific function: Unknown

COG id: COG0656

COG function: function code R; Aldo/keto reductases, related to diketogulonate reductase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Homo sapiens, GI223468663, Length=297, Percent_Identity=29.2929292929293, Blast_Score=116, Evalue=2e-26,
Organism=Homo sapiens, GI291291012, Length=265, Percent_Identity=30.5660377358491, Blast_Score=111, Evalue=6e-25,
Organism=Homo sapiens, GI93277124, Length=305, Percent_Identity=27.2131147540984, Blast_Score=100, Evalue=1e-21,
Organism=Homo sapiens, GI24497577, Length=289, Percent_Identity=28.3737024221453, Blast_Score=93, Evalue=2e-19,
Organism=Homo sapiens, GI5174391, Length=289, Percent_Identity=28.3737024221453, Blast_Score=93, Evalue=2e-19,
Organism=Homo sapiens, GI5174695, Length=302, Percent_Identity=27.1523178807947, Blast_Score=93, Evalue=3e-19,
Organism=Homo sapiens, GI4502049, Length=290, Percent_Identity=30.3448275862069, Blast_Score=91, Evalue=9e-19,
Organism=Homo sapiens, GI310109922, Length=276, Percent_Identity=29.7101449275362, Blast_Score=89, Evalue=3e-18,
Organism=Homo sapiens, GI300116273, Length=288, Percent_Identity=28.125, Blast_Score=89, Evalue=6e-18,
Organism=Homo sapiens, GI300116271, Length=276, Percent_Identity=26.8115942028986, Blast_Score=86, Evalue=5e-17,
Organism=Homo sapiens, GI24497585, Length=290, Percent_Identity=27.9310344827586, Blast_Score=83, Evalue=4e-16,
Organism=Homo sapiens, GI45446745, Length=296, Percent_Identity=28.0405405405405, Blast_Score=82, Evalue=5e-16,
Organism=Homo sapiens, GI4503285, Length=296, Percent_Identity=28.0405405405405, Blast_Score=82, Evalue=5e-16,
Organism=Homo sapiens, GI310109920, Length=296, Percent_Identity=28.0405405405405, Blast_Score=82, Evalue=5e-16,
Organism=Homo sapiens, GI5453543, Length=296, Percent_Identity=27.7027027027027, Blast_Score=80, Evalue=1e-15,
Organism=Homo sapiens, GI24497583, Length=291, Percent_Identity=27.1477663230241, Blast_Score=77, Evalue=2e-14,
Organism=Homo sapiens, GI223718702, Length=182, Percent_Identity=32.4175824175824, Blast_Score=71, Evalue=9e-13,
Organism=Escherichia coli, GI1788081, Length=284, Percent_Identity=97.5352112676056, Blast_Score=569, Evalue=1e-164,
Organism=Escherichia coli, GI1786400, Length=261, Percent_Identity=28.3524904214559, Blast_Score=99, Evalue=2e-22,
Organism=Escherichia coli, GI87081735, Length=200, Percent_Identity=32.5, Blast_Score=99, Evalue=4e-22,
Organism=Escherichia coli, GI1788070, Length=315, Percent_Identity=26.984126984127, Blast_Score=94, Evalue=1e-20,
Organism=Escherichia coli, GI87082198, Length=257, Percent_Identity=28.7937743190661, Blast_Score=92, Evalue=3e-20,
Organism=Escherichia coli, GI1789199, Length=351, Percent_Identity=27.9202279202279, Blast_Score=74, Evalue=1e-14,
Organism=Escherichia coli, GI1789375, Length=323, Percent_Identity=23.8390092879257, Blast_Score=66, Evalue=3e-12,
Organism=Caenorhabditis elegans, GI17552492, Length=273, Percent_Identity=30.03663003663, Blast_Score=113, Evalue=1e-25,
Organism=Caenorhabditis elegans, GI17561298, Length=285, Percent_Identity=31.5789473684211, Blast_Score=108, Evalue=4e-24,
Organism=Caenorhabditis elegans, GI17564128, Length=307, Percent_Identity=27.0358306188925, Blast_Score=102, Evalue=2e-22,
Organism=Caenorhabditis elegans, GI71998625, Length=277, Percent_Identity=29.9638989169675, Blast_Score=101, Evalue=5e-22,
Organism=Caenorhabditis elegans, GI17537077, Length=297, Percent_Identity=29.2929292929293, Blast_Score=98, Evalue=5e-21,
Organism=Caenorhabditis elegans, GI17537075, Length=297, Percent_Identity=29.2929292929293, Blast_Score=96, Evalue=2e-20,
Organism=Caenorhabditis elegans, GI17538386, Length=290, Percent_Identity=28.9655172413793, Blast_Score=89, Evalue=2e-18,
Organism=Caenorhabditis elegans, GI17561300, Length=288, Percent_Identity=28.4722222222222, Blast_Score=89, Evalue=3e-18,
Organism=Caenorhabditis elegans, GI17566692, Length=299, Percent_Identity=25.4180602006689, Blast_Score=86, Evalue=2e-17,
Organism=Caenorhabditis elegans, GI17550248, Length=297, Percent_Identity=24.2424242424242, Blast_Score=78, Evalue=5e-15,
Organism=Saccharomyces cerevisiae, GI6324694, Length=293, Percent_Identity=27.3037542662116, Blast_Score=89, Evalue=5e-19,
Organism=Saccharomyces cerevisiae, GI6320079, Length=287, Percent_Identity=26.1324041811847, Blast_Score=83, Evalue=5e-17,
Organism=Saccharomyces cerevisiae, GI6322556, Length=283, Percent_Identity=26.1484098939929, Blast_Score=79, Evalue=6e-16,
Organism=Drosophila melanogaster, GI24644950, Length=312, Percent_Identity=31.7307692307692, Blast_Score=114, Evalue=6e-26,
Organism=Drosophila melanogaster, GI221378297, Length=332, Percent_Identity=30.421686746988, Blast_Score=105, Evalue=3e-23,
Organism=Drosophila melanogaster, GI45553081, Length=290, Percent_Identity=24.4827586206897, Blast_Score=89, Evalue=2e-18,
Organism=Drosophila melanogaster, GI24657054, Length=291, Percent_Identity=26.4604810996564, Blast_Score=88, Evalue=6e-18,
Organism=Drosophila melanogaster, GI24663317, Length=299, Percent_Identity=23.0769230769231, Blast_Score=87, Evalue=2e-17,
Organism=Drosophila melanogaster, GI24662789, Length=309, Percent_Identity=26.2135922330097, Blast_Score=82, Evalue=6e-16,
Organism=Drosophila melanogaster, GI281366140, Length=252, Percent_Identity=25.3968253968254, Blast_Score=79, Evalue=4e-15,
Organism=Drosophila melanogaster, GI20129731, Length=297, Percent_Identity=25.2525252525253, Blast_Score=79, Evalue=4e-15,
Organism=Drosophila melanogaster, GI21356425, Length=298, Percent_Identity=23.1543624161074, Blast_Score=77, Evalue=1e-14,
Organism=Drosophila melanogaster, GI24662781, Length=288, Percent_Identity=26.3888888888889, Blast_Score=68, Evalue=6e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001395
- InterPro:   IPR020471
- InterPro:   IPR023210 [H]

Pfam domain/function: PF00248 Aldo_ket_red [H]

EC number: NA

Molecular weight: Translated: 31088; Mature: 31088

Theoretical pI: Translated: 6.25; Mature: 6.25

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
3.9 %Met     (Translated Protein)
4.9 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
3.9 %Met     (Mature Protein)
4.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQQKMIQFSGDVSLPAIGQGTWYMGEDASQRKTEVAALRAGIELGLTLIDTAEMYADGGA
CCCCEEEECCCCCCCCCCCCCEECCCCCHHHHHHHHHHHHHHHHCEEEEEHHHHHHCCCH
EKVVGEALTGLRDNVFLVSKVYPWNAGRQKAINACEASLRRLNTDYLDLYLLHWSGSFAF
HHHHHHHHHCCCCCEEEEEEECCCCCCHHHHHHHHHHHHHHCCCCCEEEEEEEECCCCHH
EETVAAMEKLIAQGKIRRWGVSNLDYADMQELWQLPGGNQCATNQVLYHLGSRGIEYDLL
HHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHCCCCCCCHHHHHHHHHHCCCCCCCCCC
PWCQQQQMPVMAYSPLAQAGRLRNGLLKNAVVNEIAHAHNISSAQVLLARVISHQGVMAI
CCCCCCCCCEEEECCHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCEEC
PKAATIAHVQQNAAVLEVELSSAELTMLDKAYPAPKGKTALDMV
CCHHHHHHHHCCCEEEEEEECCCCEEEHHHCCCCCCCCCCCCCC
>Mature Secondary Structure
MQQKMIQFSGDVSLPAIGQGTWYMGEDASQRKTEVAALRAGIELGLTLIDTAEMYADGGA
CCCCEEEECCCCCCCCCCCCCEECCCCCHHHHHHHHHHHHHHHHCEEEEEHHHHHHCCCH
EKVVGEALTGLRDNVFLVSKVYPWNAGRQKAINACEASLRRLNTDYLDLYLLHWSGSFAF
HHHHHHHHHCCCCCEEEEEEECCCCCCHHHHHHHHHHHHHHCCCCCEEEEEEEECCCCHH
EETVAAMEKLIAQGKIRRWGVSNLDYADMQELWQLPGGNQCATNQVLYHLGSRGIEYDLL
HHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHCCCCCCCHHHHHHHHHHCCCCCCCCCC
PWCQQQQMPVMAYSPLAQAGRLRNGLLKNAVVNEIAHAHNISSAQVLLARVISHQGVMAI
CCCCCCCCCEEEECCHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCEEC
PKAATIAHVQQNAAVLEVELSSAELTMLDKAYPAPKGKTALDMV
CCHHHHHHHHCCCEEEEEEECCCCEEEHHHCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9097040; 9278503 [H]