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The map label for this gene is adrB [H]

Identifier: 82543736

GI number: 82543736

Start: 1222114

End: 1222950

Strand: Direct

Name: adrB [H]

Synonym: SBO_1226

Alternate gene names: 82543736

Gene position: 1222114-1222950 (Clockwise)

Preceding gene: 82543735

Following gene: 82543739

Centisome position: 27.04

GC content: 51.25

Gene sequence:

>837_bases
GTGGGCTACATCGCCTGGCTGGCGACCGCTTACCGGATGAGCTTTTCCCGCGAAATCAATCTGGGCCTGGCGCAACATGA
GTTCGAATTGTTCTGTCAGCCTTTGCTTAATGCGCGCAGCCAGCAATGTATTGGTGTAGAGATTTTGCTGCGCTGGAACA
ATCCGCGTCAGGGCCGGATTTCACCGGATGTGTTTATTCCTATCGCGGAAGAACATCATTTAATTGTGCCACTGACCCGC
TATGTGATGGCAGAAACCATTCGTCAGCGCCATGTTTTCCCGATGAGTAGTCAGTTTCATGTTGGCATTAACGTCGCACC
CAGCCATTTTCGCCGTGGTGTGCTGATAAAAGATCTCAATCAGTACTGGTTTAGCGCTCACCCGATTCAGCAACTGATCC
TCGAAATCACCGAACGCGATGCCTTACTGGATGTTGATTATCGGATTGCCCGCGAGCTACATCGTAAAAACGTCAAACTG
GCGATTGATGACTTCGGCACCGGCAACAGTTCATTTTCCTGGCTTGAAACATTACGTCCTGACGTGCTGAAAATTGATAA
GTCATTTACCGCAGCTATAGGTTCTGACGCGGTTAACTCGACGGTGACCGATATCATCATCGCGCTGGGGCAAAGACTGA
ATATTGAACTGGTGGCGGAGGGCGTGGAAACGCAAGAACAGGCGAAGTATTTGCGCCGTCATGGCGTGCATATTTTGCAA
GGGTATTTGTACGCACAGCCGATGCCGCTACGCGATTTTCCCAAATGGCTGGCGGGCAGCCAACCGCCGCCCGCCCGGCA
TAATGGACATATCACGCCCATTATGCCGTTACGTTAA

Upstream 100 bases:

>100_bases
TATCTCCCCGGCAGCCTTCAGGGAAAAATATCATCAGATGGCTGCTTAAAAAAAGAACAAATGGTAGTGTCCGCTATTGC
CAGTACACCTCAGTTTACTG

Downstream 100 bases:

>100_bases
CGCTGATATGACTTTCCGTGTCAAACCGGAATCTCTAATTTTGACGATTTTCTTTTTAGGTTTAATTCCCTGAGGGCGAC
GTAGCAGTAAATCCGACGGT

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 278; Mature: 277

Protein sequence:

>278_residues
MGYIAWLATAYRMSFSREINLGLAQHEFELFCQPLLNARSQQCIGVEILLRWNNPRQGRISPDVFIPIAEEHHLIVPLTR
YVMAETIRQRHVFPMSSQFHVGINVAPSHFRRGVLIKDLNQYWFSAHPIQQLILEITERDALLDVDYRIARELHRKNVKL
AIDDFGTGNSSFSWLETLRPDVLKIDKSFTAAIGSDAVNSTVTDIIIALGQRLNIELVAEGVETQEQAKYLRRHGVHILQ
GYLYAQPMPLRDFPKWLAGSQPPPARHNGHITPIMPLR

Sequences:

>Translated_278_residues
MGYIAWLATAYRMSFSREINLGLAQHEFELFCQPLLNARSQQCIGVEILLRWNNPRQGRISPDVFIPIAEEHHLIVPLTR
YVMAETIRQRHVFPMSSQFHVGINVAPSHFRRGVLIKDLNQYWFSAHPIQQLILEITERDALLDVDYRIARELHRKNVKL
AIDDFGTGNSSFSWLETLRPDVLKIDKSFTAAIGSDAVNSTVTDIIIALGQRLNIELVAEGVETQEQAKYLRRHGVHILQ
GYLYAQPMPLRDFPKWLAGSQPPPARHNGHITPIMPLR
>Mature_277_residues
GYIAWLATAYRMSFSREINLGLAQHEFELFCQPLLNARSQQCIGVEILLRWNNPRQGRISPDVFIPIAEEHHLIVPLTRY
VMAETIRQRHVFPMSSQFHVGINVAPSHFRRGVLIKDLNQYWFSAHPIQQLILEITERDALLDVDYRIARELHRKNVKLA
IDDFGTGNSSFSWLETLRPDVLKIDKSFTAAIGSDAVNSTVTDIIIALGQRLNIELVAEGVETQEQAKYLRRHGVHILQG
YLYAQPMPLRDFPKWLAGSQPPPARHNGHITPIMPLR

Specific function: May serve as a negative regulator of cellulose synthesis (as has been suggested for S.typhimurium); over-expression inhibits cell aggregation in strains able to produce adhesive curli fimbriae. Cyclic-di-GMP is a second messenger which controls cell surfa

COG id: COG2200

COG function: function code T; FOG: EAL domain

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 EAL domain [H]

Homologues:

Organism=Escherichia coli, GI87081980, Length=278, Percent_Identity=99.2805755395683, Blast_Score=575, Evalue=1e-165,
Organism=Escherichia coli, GI1788502, Length=270, Percent_Identity=39.2592592592593, Blast_Score=190, Evalue=8e-50,
Organism=Escherichia coli, GI1786507, Length=247, Percent_Identity=39.2712550607287, Blast_Score=168, Evalue=4e-43,
Organism=Escherichia coli, GI87081845, Length=256, Percent_Identity=37.890625, Blast_Score=158, Evalue=3e-40,
Organism=Escherichia coli, GI1790496, Length=259, Percent_Identity=35.1351351351351, Blast_Score=153, Evalue=1e-38,
Organism=Escherichia coli, GI87081921, Length=261, Percent_Identity=33.3333333333333, Blast_Score=138, Evalue=5e-34,
Organism=Escherichia coli, GI87081743, Length=235, Percent_Identity=35.3191489361702, Blast_Score=126, Evalue=2e-30,
Organism=Escherichia coli, GI1787541, Length=259, Percent_Identity=30.5019305019305, Blast_Score=117, Evalue=6e-28,
Organism=Escherichia coli, GI226510982, Length=260, Percent_Identity=31.5384615384615, Blast_Score=111, Evalue=5e-26,
Organism=Escherichia coli, GI1788849, Length=249, Percent_Identity=30.1204819277108, Blast_Score=102, Evalue=3e-23,
Organism=Escherichia coli, GI87082096, Length=242, Percent_Identity=29.7520661157025, Blast_Score=102, Evalue=3e-23,
Organism=Escherichia coli, GI1787055, Length=254, Percent_Identity=30.3149606299213, Blast_Score=101, Evalue=5e-23,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001633 [H]

Pfam domain/function: PF00563 EAL [H]

EC number: =3.1.4.52 [H]

Molecular weight: Translated: 31844; Mature: 31713

Theoretical pI: Translated: 8.67; Mature: 8.67

Prosite motif: PS50883 EAL

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGYIAWLATAYRMSFSREINLGLAQHEFELFCQPLLNARSQQCIGVEILLRWNNPRQGRI
CCHHHHHHHHHHHHHCCEECCCHHHHHHHHHHHHHHCCCCCCCEEEEEEEEECCCCCCCC
SPDVFIPIAEEHHLIVPLTRYVMAETIRQRHVFPMSSQFHVGINVAPSHFRRGVLIKDLN
CCCEEEEECCCCEEEHHHHHHHHHHHHHHHCCCCCCCCEEEEEEECHHHHHCCHHHHHHH
QYWFSAHPIQQLILEITERDALLDVDYRIARELHRKNVKLAIDDFGTGNSSFSWLETLRP
HHHCCCCHHHHHHHHHHHCCCEECHHHHHHHHHHHCCCEEEEECCCCCCCCHHHHHHCCC
DVLKIDKSFTAAIGSDAVNSTVTDIIIALGQRLNIELVAEGVETQEQAKYLRRHGVHILQ
HHEECCCHHHHHHCCHHHHHHHHHHHHHHCCCCCEEEEECCCCHHHHHHHHHHCCHHHHH
GYLYAQPMPLRDFPKWLAGSQPPPARHNGHITPIMPLR
HHHHCCCCCHHHHHHHHCCCCCCCCCCCCCCCEECCCC
>Mature Secondary Structure 
GYIAWLATAYRMSFSREINLGLAQHEFELFCQPLLNARSQQCIGVEILLRWNNPRQGRI
CHHHHHHHHHHHHHCCEECCCHHHHHHHHHHHHHHCCCCCCCEEEEEEEEECCCCCCCC
SPDVFIPIAEEHHLIVPLTRYVMAETIRQRHVFPMSSQFHVGINVAPSHFRRGVLIKDLN
CCCEEEEECCCCEEEHHHHHHHHHHHHHHHCCCCCCCCEEEEEEECHHHHHCCHHHHHHH
QYWFSAHPIQQLILEITERDALLDVDYRIARELHRKNVKLAIDDFGTGNSSFSWLETLRP
HHHCCCCHHHHHHHHHHHCCCEECHHHHHHHHHHHCCCEEEEECCCCCCCCHHHHHHCCC
DVLKIDKSFTAAIGSDAVNSTVTDIIIALGQRLNIELVAEGVETQEQAKYLRRHGVHILQ
HHEECCCHHHHHHCCHHHHHHHHHHHHHHCCCCCEEEEECCCCHHHHHHHHHHCCHHHHH
GYLYAQPMPLRDFPKWLAGSQPPPARHNGHITPIMPLR
HHHHCCCCCHHHHHHHHCCCCCCCCCCCCCCCEECCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9097040; 9278503 [H]