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The map label for this gene is cobT [H]

Identifier: 82543727

GI number: 82543727

Start: 1210343

End: 1211368

Strand: Direct

Name: cobT [H]

Synonym: SBO_1212

Alternate gene names: 82543727

Gene position: 1210343-1211368 (Clockwise)

Preceding gene: 82543726

Following gene: 82543728

Centisome position: 26.78

GC content: 52.63

Gene sequence:

>1026_bases
ATGTCGCGTGCACAACGGCATATCGACGGGTTACTCAAACCTGTTGGTAGCCTGGGAAGGCTGGAGGCGCTTGCCATACA
ACTGGCAGGAATGCCGGGGTTGAATGGCGTTCCGCATGTGGGCAAAAAAGCGGTACTGGTCATGTGTGCCGATCACGGCG
TCTGGGAGGAAGGGGGCGCTATTTCCCCAAAAGAAGTGACAGCCATTCAGGCTGAAAATATGACCCGCGGAACAACCGGC
GTGTGTGTGCTGGCAGCACAAGCGGGCGCTAACGTCTACGTAATTGATGTTGGTATTGATACTGCTGAGCCTATCCCCGG
GCTTATCAACATGCGTGTTGCTCGAGGTAGTGGCAATATTGCTTCAGCTCCGGCAATGAGTCGCCATCAGGCAGAAAAGT
TGCTTTTGGACGTCATATGTTATACGCGGGAGCTGGCAAAAAACGGTGTTACGCTGTTTGGTGTAGGTGAACTGGGGATG
GCAAACACGACACCGGCAGCGGCAATAGTCAGCACAATCACTGGCCGGGCTCCTGAAGAAGTGGTTGGGATTGGCGCAAA
CCTGCCGACAGATAAACTGGCTAATAAAATTGATGTTGTGCGCCGGGCGATTACGTTGAATCAACCAAATCCGCAGGATG
GCGTTGATGTCCTGGCAAAAGTGGGTGGATTTGATTTGGTCGGAATGGCTGGCGTGATGTTAGGCGCTGCGTCCTGCGGT
TTACCCGTGTTGCTGGATGGATTTCTTTCTTATGCTGCTGCGCTCGCAGCCTGTCAGATGTCTCCTGCAATCAAACCGTA
TCTCATTCCTTCTCACCTGTCGGCAGAAAAAGGAGCGCGTATAGCGCTGTCGCATTTGGGGCTGGAGCCTTATCTCAATA
TGGAGATGCGTTTAGGTGAGGGGAGTGGCGCAGCTCTGGCGATGCCCATCATCGAAGCTGCCTGTGCGATATATAACAAC
ATGGGCGAACTTGCTGCCAGTAATATTGTTCTACCGGGGAATACGACTTCTGATTTGAACAGTTAA

Upstream 100 bases:

>100_bases
TTGGTGAACTGGTCTTCCTGCTGGCACTGCTATAAAGAGACGTGACATTCAAACACTTGCCGATTTACTGAATACGATCC
CTGCTATCGATCCTGCCGCT

Downstream 100 bases:

>100_bases
AAACGAAAAGTCTGATAAAAGCTATACTTAACGGATAGCTTTCGCGACTTAGGAAAGGGACATGATGCGTCGTGTAAATA
TTTTTTGCTCATTTGCTCTG

Product: nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase

Products: NA

Alternate protein names: NN:DBI PRT; N(1)-alpha-phosphoribosyltransferase [H]

Number of amino acids: Translated: 341; Mature: 340

Protein sequence:

>341_residues
MSRAQRHIDGLLKPVGSLGRLEALAIQLAGMPGLNGVPHVGKKAVLVMCADHGVWEEGGAISPKEVTAIQAENMTRGTTG
VCVLAAQAGANVYVIDVGIDTAEPIPGLINMRVARGSGNIASAPAMSRHQAEKLLLDVICYTRELAKNGVTLFGVGELGM
ANTTPAAAIVSTITGRAPEEVVGIGANLPTDKLANKIDVVRRAITLNQPNPQDGVDVLAKVGGFDLVGMAGVMLGAASCG
LPVLLDGFLSYAAALAACQMSPAIKPYLIPSHLSAEKGARIALSHLGLEPYLNMEMRLGEGSGAALAMPIIEAACAIYNN
MGELAASNIVLPGNTTSDLNS

Sequences:

>Translated_341_residues
MSRAQRHIDGLLKPVGSLGRLEALAIQLAGMPGLNGVPHVGKKAVLVMCADHGVWEEGGAISPKEVTAIQAENMTRGTTG
VCVLAAQAGANVYVIDVGIDTAEPIPGLINMRVARGSGNIASAPAMSRHQAEKLLLDVICYTRELAKNGVTLFGVGELGM
ANTTPAAAIVSTITGRAPEEVVGIGANLPTDKLANKIDVVRRAITLNQPNPQDGVDVLAKVGGFDLVGMAGVMLGAASCG
LPVLLDGFLSYAAALAACQMSPAIKPYLIPSHLSAEKGARIALSHLGLEPYLNMEMRLGEGSGAALAMPIIEAACAIYNN
MGELAASNIVLPGNTTSDLNS
>Mature_340_residues
SRAQRHIDGLLKPVGSLGRLEALAIQLAGMPGLNGVPHVGKKAVLVMCADHGVWEEGGAISPKEVTAIQAENMTRGTTGV
CVLAAQAGANVYVIDVGIDTAEPIPGLINMRVARGSGNIASAPAMSRHQAEKLLLDVICYTRELAKNGVTLFGVGELGMA
NTTPAAAIVSTITGRAPEEVVGIGANLPTDKLANKIDVVRRAITLNQPNPQDGVDVLAKVGGFDLVGMAGVMLGAASCGL
PVLLDGFLSYAAALAACQMSPAIKPYLIPSHLSAEKGARIALSHLGLEPYLNMEMRLGEGSGAALAMPIIEAACAIYNNM
GELAASNIVLPGNTTSDLNS

Specific function: Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6- dimethylbenzimidazole (DMB) [H]

COG id: COG2038

COG function: function code H; NaMN:DMB phosphoribosyltransferase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the CobT family [H]

Homologues:

Organism=Escherichia coli, GI1788300, Length=341, Percent_Identity=97.0674486803519, Blast_Score=664, Evalue=0.0,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003200
- InterPro:   IPR023195
- InterPro:   IPR017846 [H]

Pfam domain/function: PF02277 DBI_PRT [H]

EC number: =2.4.2.21 [H]

Molecular weight: Translated: 35000; Mature: 34869

Theoretical pI: Translated: 5.95; Mature: 5.95

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
4.1 %Met     (Translated Protein)
5.9 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
3.8 %Met     (Mature Protein)
5.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSRAQRHIDGLLKPVGSLGRLEALAIQLAGMPGLNGVPHVGKKAVLVMCADHGVWEEGGA
CCHHHHHHHHHHHHHCCHHHHHHHHHEECCCCCCCCCCCCCCCEEEEEEECCCCCCCCCC
ISPKEVTAIQAENMTRGTTGVCVLAAQAGANVYVIDVGIDTAEPIPGLINMRVARGSGNI
CCCHHEEEEECCCCCCCCCCEEEEEEECCCEEEEEEECCCCCCCCCCCEEEEEECCCCCC
ASAPAMSRHQAEKLLLDVICYTRELAKNGVTLFGVGELGMANTTPAAAIVSTITGRAPEE
CCCCCHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCCCCCCHHHHHHHHHCCCCCHH
VVGIGANLPTDKLANKIDVVRRAITLNQPNPQDGVDVLAKVGGFDLVGMAGVMLGAASCG
HEECCCCCCHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHCCCHHHHHHHHHHHHHHCC
LPVLLDGFLSYAAALAACQMSPAIKPYLIPSHLSAEKGARIALSHLGLEPYLNMEMRLGE
HHHHHHHHHHHHHHHHHHHCCCCCCCEECCCCCCCCCCCEEEHHHCCCCCCCCEEEEECC
GSGAALAMPIIEAACAIYNNMGELAASNIVLPGNTTSDLNS
CCCCEEHHHHHHHHHHHHHHHHHHHHCCEEECCCCCCCCCC
>Mature Secondary Structure 
SRAQRHIDGLLKPVGSLGRLEALAIQLAGMPGLNGVPHVGKKAVLVMCADHGVWEEGGA
CHHHHHHHHHHHHHCCHHHHHHHHHEECCCCCCCCCCCCCCCEEEEEEECCCCCCCCCC
ISPKEVTAIQAENMTRGTTGVCVLAAQAGANVYVIDVGIDTAEPIPGLINMRVARGSGNI
CCCHHEEEEECCCCCCCCCCEEEEEEECCCEEEEEEECCCCCCCCCCCEEEEEECCCCCC
ASAPAMSRHQAEKLLLDVICYTRELAKNGVTLFGVGELGMANTTPAAAIVSTITGRAPEE
CCCCCHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCCCCCCHHHHHHHHHCCCCCHH
VVGIGANLPTDKLANKIDVVRRAITLNQPNPQDGVDVLAKVGGFDLVGMAGVMLGAASCG
HEECCCCCCHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHCCCHHHHHHHHHHHHHHCC
LPVLLDGFLSYAAALAACQMSPAIKPYLIPSHLSAEKGARIALSHLGLEPYLNMEMRLGE
HHHHHHHHHHHHHHHHHHHCCCCCCCEECCCCCCCCCCCEEEHHHCCCCCCCCEEEEECC
GSGAALAMPIIEAACAIYNNMGELAASNIVLPGNTTSDLNS
CCCCEEHHHHHHHHHHHHHHHHHHHHCCEEECCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA