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The map label for this gene is ugd [H]

Identifier: 82543408

GI number: 82543408

Start: 870640

End: 871806

Strand: Reverse

Name: ugd [H]

Synonym: SBO_0857

Alternate gene names: 82543408

Gene position: 871806-870640 (Counterclockwise)

Preceding gene: 82543409

Following gene: 82543406

Centisome position: 19.29

GC content: 42.5

Gene sequence:

>1167_bases
ATGAAAATAACAATTTCAGGAACAGGTTATGTTGGTCTTTCAAATGGTATTCTGATTGCGCAAAACCACGAAGTGGTTGC
ACTGGATATCGTTCAGGCCAAAGTGGACATGCTTAACAAGAGGCAGTCACCGCTTGTTGATAAGGAGATTGAAGAGTATC
TGGCGACTAAAGATCTCAATTTCCGCGCTACGACAGATAAGTATGACGCGTATAAAAATGCCGATTACGTTATTATTGCC
ACACCTACCGATTATGATCCGAAAACAAATTATTTTAATACCTCAAGCGTGGAAGCGGTCATTCGTGATGTGACAGAAAT
TAATCCCAACGCGGTAATGATTATAAAATCAACTATCCCTGTTGGTTTTACAGAGTCCATTAAAGAACGTTTTGGTATTG
AAAATGTGATCTTTTCGCCTGAGTTTTTGCGTGAAGGTAAAGCACTTTATGATAACTTACACCCATCACGCATTGTGATT
GGCGAGCAGTCTGAACGCGCTAAACGTTTTGCTGCGTTATTACAGGAAGGCGCCATTAAGCAAGACATACCAACATTGTT
TACTGACTCAACCGAGGCTGAGGCGATTAAACTTTTTGCGAACACTTATCTGGCGATGCGTGTAGCGTATTTCAATGAAC
TTGATAGTTATGCTGAAAGCCTGGGACTTAATTCACGCCAGATTATTGAGGGCGTATGCCTTGACCCGCGTATCGGTAAT
CACTACAACAACCCGTCATTCGGTTATGGTGGTTATTGTCTGCCGAAAGATACTAAGCAGTTACTGGCAAATTACCAGTC
TGTGCCGAATAACCTGATCTCGGCAATTGTTGACGCCAACCGCACGCGCAAAGATTTTATTGCCGATTCTATCCTTGCAC
GTAAACCGAAAGTTGTTGGCGTCTATCGTTTGATTATGAAGAATGGTTCAGACAATTTTCGTGCTTCCTCGATTCAGGGT
ATTATGAAGCGAATCAAGGCGAAAGGTGTGCCTGTAATCGTTTATGAGCCAGCTATGAAAGAGGACGATTTTTTCCGGTC
GCGCGTGGTACGTGATCTGGATGCGTTCAAACAAGAAGCTGATGTTATTATTTCTAACCGTATGTCTGCCGATCTGGCTG
ATGTAGCAGATAAAGTTTATACGCGCGACTTGTTTGGCAATGATTAA

Upstream 100 bases:

>100_bases
ACAGTTCATCTACATCAGCGTTAAAAATCCCGCAGTAGATGAAGCTGTGGTGGTGGATTAATGACCACTCTAAATGTTTA
ACCGGAAGAAGTCAGAGCTA

Downstream 100 bases:

>100_bases
TTATTTTGTTTCATTCTAAGAAAAGGCCCTAATAAATTAGGGCCTTTTCTTATGGTTTTGTAAAATCAAACTTTATAGAA
GTTACGATACCATTCTACAA

Product: UDP-glucose 6-dehydrogenase

Products: NA

Alternate protein names: UDP-Glc dehydrogenase; UDP-GlcDH; UDPGDH [H]

Number of amino acids: Translated: 388; Mature: 388

Protein sequence:

>388_residues
MKITISGTGYVGLSNGILIAQNHEVVALDIVQAKVDMLNKRQSPLVDKEIEEYLATKDLNFRATTDKYDAYKNADYVIIA
TPTDYDPKTNYFNTSSVEAVIRDVTEINPNAVMIIKSTIPVGFTESIKERFGIENVIFSPEFLREGKALYDNLHPSRIVI
GEQSERAKRFAALLQEGAIKQDIPTLFTDSTEAEAIKLFANTYLAMRVAYFNELDSYAESLGLNSRQIIEGVCLDPRIGN
HYNNPSFGYGGYCLPKDTKQLLANYQSVPNNLISAIVDANRTRKDFIADSILARKPKVVGVYRLIMKNGSDNFRASSIQG
IMKRIKAKGVPVIVYEPAMKEDDFFRSRVVRDLDAFKQEADVIISNRMSADLADVADKVYTRDLFGND

Sequences:

>Translated_388_residues
MKITISGTGYVGLSNGILIAQNHEVVALDIVQAKVDMLNKRQSPLVDKEIEEYLATKDLNFRATTDKYDAYKNADYVIIA
TPTDYDPKTNYFNTSSVEAVIRDVTEINPNAVMIIKSTIPVGFTESIKERFGIENVIFSPEFLREGKALYDNLHPSRIVI
GEQSERAKRFAALLQEGAIKQDIPTLFTDSTEAEAIKLFANTYLAMRVAYFNELDSYAESLGLNSRQIIEGVCLDPRIGN
HYNNPSFGYGGYCLPKDTKQLLANYQSVPNNLISAIVDANRTRKDFIADSILARKPKVVGVYRLIMKNGSDNFRASSIQG
IMKRIKAKGVPVIVYEPAMKEDDFFRSRVVRDLDAFKQEADVIISNRMSADLADVADKVYTRDLFGND
>Mature_388_residues
MKITISGTGYVGLSNGILIAQNHEVVALDIVQAKVDMLNKRQSPLVDKEIEEYLATKDLNFRATTDKYDAYKNADYVIIA
TPTDYDPKTNYFNTSSVEAVIRDVTEINPNAVMIIKSTIPVGFTESIKERFGIENVIFSPEFLREGKALYDNLHPSRIVI
GEQSERAKRFAALLQEGAIKQDIPTLFTDSTEAEAIKLFANTYLAMRVAYFNELDSYAESLGLNSRQIIEGVCLDPRIGN
HYNNPSFGYGGYCLPKDTKQLLANYQSVPNNLISAIVDANRTRKDFIADSILARKPKVVGVYRLIMKNGSDNFRASSIQG
IMKRIKAKGVPVIVYEPAMKEDDFFRSRVVRDLDAFKQEADVIISNRMSADLADVADKVYTRDLFGND

Specific function: Unknown

COG id: COG1004

COG function: function code M; Predicted UDP-glucose 6-dehydrogenase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the UDP-glucose/GDP-mannose dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI4507813, Length=385, Percent_Identity=29.0909090909091, Blast_Score=115, Evalue=7e-26,
Organism=Homo sapiens, GI296040438, Length=280, Percent_Identity=28.9285714285714, Blast_Score=93, Evalue=4e-19,
Organism=Homo sapiens, GI296040443, Length=233, Percent_Identity=28.3261802575107, Blast_Score=83, Evalue=5e-16,
Organism=Escherichia coli, GI1788340, Length=388, Percent_Identity=83.5051546391753, Blast_Score=680, Evalue=0.0,
Organism=Escherichia coli, GI48994968, Length=289, Percent_Identity=26.2975778546713, Blast_Score=85, Evalue=8e-18,
Organism=Caenorhabditis elegans, GI17560350, Length=397, Percent_Identity=26.448362720403, Blast_Score=112, Evalue=4e-25,
Organism=Drosophila melanogaster, GI17136908, Length=372, Percent_Identity=25.5376344086022, Blast_Score=115, Evalue=6e-26,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008927
- InterPro:   IPR013328
- InterPro:   IPR016040
- InterPro:   IPR017476
- InterPro:   IPR014027
- InterPro:   IPR014026
- InterPro:   IPR014028
- InterPro:   IPR001732 [H]

Pfam domain/function: PF00984 UDPG_MGDP_dh; PF03720 UDPG_MGDP_dh_C; PF03721 UDPG_MGDP_dh_N [H]

EC number: =1.1.1.22 [H]

Molecular weight: Translated: 43478; Mature: 43478

Theoretical pI: Translated: 5.58; Mature: 5.58

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKITISGTGYVGLSNGILIAQNHEVVALDIVQAKVDMLNKRQSPLVDKEIEEYLATKDLN
CEEEEECCCEEEECCCEEEECCCCEEEEHHHHHHHHHHHCCCCCCHHHHHHHHHHHCCCC
FRATTDKYDAYKNADYVIIATPTDYDPKTNYFNTSSVEAVIRDVTEINPNAVMIIKSTIP
EEECCCHHHHHCCCCEEEEECCCCCCCCCCCCCCHHHHHHHHHHHHCCCCEEEEEEECCC
VGFTESIKERFGIENVIFSPEFLREGKALYDNLHPSRIVIGEQSERAKRFAALLQEGAIK
CCHHHHHHHHCCCCCEEECHHHHHCCHHHHHCCCCCEEEECCCHHHHHHHHHHHHHCCHH
QDIPTLFTDSTEAEAIKLFANTYLAMRVAYFNELDSYAESLGLNSRQIIEGVCLDPRIGN
HCCCHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHCEECCCCCCC
HYNNPSFGYGGYCLPKDTKQLLANYQSVPNNLISAIVDANRTRKDFIADSILARKPKVVG
CCCCCCCCCCCEECCHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCHHH
VYRLIMKNGSDNFRASSIQGIMKRIKAKGVPVIVYEPAMKEDDFFRSRVVRDLDAFKQEA
HHHHHHHCCCCCCHHHHHHHHHHHHHHCCCCEEEECCCCCCHHHHHHHHHHHHHHHHHHH
DVIISNRMSADLADVADKVYTRDLFGND
HHHHHCCCCCHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MKITISGTGYVGLSNGILIAQNHEVVALDIVQAKVDMLNKRQSPLVDKEIEEYLATKDLN
CEEEEECCCEEEECCCEEEECCCCEEEEHHHHHHHHHHHCCCCCCHHHHHHHHHHHCCCC
FRATTDKYDAYKNADYVIIATPTDYDPKTNYFNTSSVEAVIRDVTEINPNAVMIIKSTIP
EEECCCHHHHHCCCCEEEEECCCCCCCCCCCCCCHHHHHHHHHHHHCCCCEEEEEEECCC
VGFTESIKERFGIENVIFSPEFLREGKALYDNLHPSRIVIGEQSERAKRFAALLQEGAIK
CCHHHHHHHHCCCCCEEECHHHHHCCHHHHHCCCCCEEEECCCHHHHHHHHHHHHHCCHH
QDIPTLFTDSTEAEAIKLFANTYLAMRVAYFNELDSYAESLGLNSRQIIEGVCLDPRIGN
HCCCHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHCEECCCCCCC
HYNNPSFGYGGYCLPKDTKQLLANYQSVPNNLISAIVDANRTRKDFIADSILARKPKVVG
CCCCCCCCCCCEECCHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCHHH
VYRLIMKNGSDNFRASSIQGIMKRIKAKGVPVIVYEPAMKEDDFFRSRVVRDLDAFKQEA
HHHHHHHCCCCCCHHHHHHHHHHHHHHCCCCEEEECCCCCCHHHHHHHHHHHHHHHHHHH
DVIISNRMSADLADVADKVYTRDLFGND
HHHHHCCCCCHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9383197 [H]