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The map label for this gene is nadA [H]

Identifier: 82543170

GI number: 82543170

Start: 625737

End: 626780

Strand: Direct

Name: nadA [H]

Synonym: SBO_0605

Alternate gene names: 82543170

Gene position: 625737-626780 (Clockwise)

Preceding gene: 82543169

Following gene: 82543171

Centisome position: 13.84

GC content: 50.19

Gene sequence:

>1044_bases
ATGAGCGTAATGTTTGATCCAGACACGGCGATTTATCCTTTCCCCCCGAAGCCGACGCCGTTAAGCATTGATGAAAAAGC
GTATTACCGCGAGAAGATAAAACGTCTGCTAAAAGAACGTAATGCGGTGATGGTTGCCCACTACTATACCGATCCCGAAA
TTCAACAACTGGCAGAAGAAACCGGTGGCTGTATTTCTGATTCTCTGGAAATGGCGCGCTTCGGTGCAAAGCATCCCGCT
TCTACTTTGTTAGTCGCTGGGGTGAGATTTATGGGAGAAACCGCCAAAATTCTCAGTCCGGAAAAAACAATTCTGATGCC
GACACTTCAGGCTGAATGTTCACTGGATCTCGGCTGCCCTGTTGAAGAATTTAACGCATTTTGCGATGCCCATCCCGATC
GTACTGTCGTCGTCTACGCCAACACTTCTGCTGCGGTAAAAGCGCGCGCAGATTGGGTGGTAACTTCAAGCATTGCCGTC
GAACTTATTGATCATCTTGATAGTTTGGGTGAAAAAATCATCTGGGCACCCGACAAACATCTGGGGCGTTACGTGCAAAA
ACAGACGGGTGGAGACATTCTATGCTGGCAGGGTGCCTGTATTGTGCATGATGAATTTAAGACTCAGGCGTTAACCCGCT
TGCAAGAAGAATACCCGGATGCTGCCATACTGGTGCATCCAGAATCACCACAAGCTATTGTCGATATGGCGGATGCGGTC
GGTTCCACCAGTCAACTGATCGCTGCTGCGAAAACATTGCCACATCAGAGGCTTATTGTGGCAACCGATCGGGGTATTTT
CTACAAAATGCAGCAGGCGGTGCCAGATAAAGAGTTACTGGAAGCACCAACCGCAGGTGAGGGCGCAACCTGCCGCAGCT
GCGCGCATTGTCCGTGGATGGCCATGAATGACCTTCAGGCTATCGCAGAGGCATTAGAACAGGAAGGAAGTAATCACGAG
GTTCATGTCGATGAGAGGCTGCGAGAGAGGGCGCTGGTGCCGCTCAATCGTATGCTGGATTTTGCGGCTACACTACGTGG
ATAA

Upstream 100 bases:

>100_bases
TCGACTATCTTGTTTAGCATATAAAACAAATTACACCGATAACAGCGAATGTTACGCTAATGTCGGTTTTAACGTTAAGC
CTGTAAAACGAGATGGTAAG

Downstream 100 bases:

>100_bases
CGAATAATAAGGCGTAACGTTACGCTTTGGGGGAAAGATGGATTTTTTTAGTGTGCAGAATATCCTGGTACATATACCAA
TAGGGGCGGGCGGTTATGAT

Product: quinolinate synthetase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 347; Mature: 346

Protein sequence:

>347_residues
MSVMFDPDTAIYPFPPKPTPLSIDEKAYYREKIKRLLKERNAVMVAHYYTDPEIQQLAEETGGCISDSLEMARFGAKHPA
STLLVAGVRFMGETAKILSPEKTILMPTLQAECSLDLGCPVEEFNAFCDAHPDRTVVVYANTSAAVKARADWVVTSSIAV
ELIDHLDSLGEKIIWAPDKHLGRYVQKQTGGDILCWQGACIVHDEFKTQALTRLQEEYPDAAILVHPESPQAIVDMADAV
GSTSQLIAAAKTLPHQRLIVATDRGIFYKMQQAVPDKELLEAPTAGEGATCRSCAHCPWMAMNDLQAIAEALEQEGSNHE
VHVDERLRERALVPLNRMLDFAATLRG

Sequences:

>Translated_347_residues
MSVMFDPDTAIYPFPPKPTPLSIDEKAYYREKIKRLLKERNAVMVAHYYTDPEIQQLAEETGGCISDSLEMARFGAKHPA
STLLVAGVRFMGETAKILSPEKTILMPTLQAECSLDLGCPVEEFNAFCDAHPDRTVVVYANTSAAVKARADWVVTSSIAV
ELIDHLDSLGEKIIWAPDKHLGRYVQKQTGGDILCWQGACIVHDEFKTQALTRLQEEYPDAAILVHPESPQAIVDMADAV
GSTSQLIAAAKTLPHQRLIVATDRGIFYKMQQAVPDKELLEAPTAGEGATCRSCAHCPWMAMNDLQAIAEALEQEGSNHE
VHVDERLRERALVPLNRMLDFAATLRG
>Mature_346_residues
SVMFDPDTAIYPFPPKPTPLSIDEKAYYREKIKRLLKERNAVMVAHYYTDPEIQQLAEETGGCISDSLEMARFGAKHPAS
TLLVAGVRFMGETAKILSPEKTILMPTLQAECSLDLGCPVEEFNAFCDAHPDRTVVVYANTSAAVKARADWVVTSSIAVE
LIDHLDSLGEKIIWAPDKHLGRYVQKQTGGDILCWQGACIVHDEFKTQALTRLQEEYPDAAILVHPESPQAIVDMADAVG
STSQLIAAAKTLPHQRLIVATDRGIFYKMQQAVPDKELLEAPTAGEGATCRSCAHCPWMAMNDLQAIAEALEQEGSNHEV
HVDERLRERALVPLNRMLDFAATLRG

Specific function: Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate [H]

COG id: COG0379

COG function: function code H; Quinolinate synthase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the quinolinate synthase A family. Type 1 subfamily [H]

Homologues:

Organism=Escherichia coli, GI1786964, Length=347, Percent_Identity=99.7118155619597, Blast_Score=718, Evalue=0.0,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003473 [H]

Pfam domain/function: PF02445 NadA [H]

EC number: =2.5.1.72 [H]

Molecular weight: Translated: 38299; Mature: 38168

Theoretical pI: Translated: 4.94; Mature: 4.94

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.6 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
5.8 %Cys+Met (Translated Protein)
2.6 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
5.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSVMFDPDTAIYPFPPKPTPLSIDEKAYYREKIKRLLKERNAVMVAHYYTDPEIQQLAEE
CCEEECCCCEEECCCCCCCCCCCCHHHHHHHHHHHHHHHCCEEEEEEECCCHHHHHHHHH
TGGCISDSLEMARFGAKHPASTLLVAGVRFMGETAKILSPEKTILMPTLQAECSLDLGCP
HCCHHHHHHHHHHCCCCCCHHHHHHHHHHHHCCHHHHCCCCCEEEEEECCCCCCCCCCCC
VEEFNAFCDAHPDRTVVVYANTSAAVKARADWVVTSSIAVELIDHLDSLGEKIIWAPDKH
HHHHHHHHCCCCCCEEEEEECCCCEEEECCCEEEHHHHHHHHHHHHHHHCCCEEECCCHH
LGRYVQKQTGGDILCWQGACIVHDEFKTQALTRLQEEYPDAAILVHPESPQAIVDMADAV
HHHHHHHHCCCCEEEECCEEEEEHHHHHHHHHHHHHHCCCCEEEEECCCCHHHHHHHHHH
GSTSQLIAAAKTLPHQRLIVATDRGIFYKMQQAVPDKELLEAPTAGEGATCRSCAHCPWM
CCHHHHHHHHHHCCCCEEEEEECCCHHHHHHHHCCCHHHHCCCCCCCCCCCHHHCCCCCH
AMNDLQAIAEALEQEGSNHEVHVDERLRERALVPLNRMLDFAATLRG
HHHHHHHHHHHHHHCCCCCEEEHHHHHHHHHCCCHHHHHHHHHHHCC
>Mature Secondary Structure 
SVMFDPDTAIYPFPPKPTPLSIDEKAYYREKIKRLLKERNAVMVAHYYTDPEIQQLAEE
CEEECCCCEEECCCCCCCCCCCCHHHHHHHHHHHHHHHCCEEEEEEECCCHHHHHHHHH
TGGCISDSLEMARFGAKHPASTLLVAGVRFMGETAKILSPEKTILMPTLQAECSLDLGCP
HCCHHHHHHHHHHCCCCCCHHHHHHHHHHHHCCHHHHCCCCCEEEEEECCCCCCCCCCCC
VEEFNAFCDAHPDRTVVVYANTSAAVKARADWVVTSSIAVELIDHLDSLGEKIIWAPDKH
HHHHHHHHCCCCCCEEEEEECCCCEEEECCCEEEHHHHHHHHHHHHHHHCCCEEECCCHH
LGRYVQKQTGGDILCWQGACIVHDEFKTQALTRLQEEYPDAAILVHPESPQAIVDMADAV
HHHHHHHHCCCCEEEECCEEEEEHHHHHHHHHHHHHHCCCCEEEEECCCCHHHHHHHHHH
GSTSQLIAAAKTLPHQRLIVATDRGIFYKMQQAVPDKELLEAPTAGEGATCRSCAHCPWM
CCHHHHHHHHHHCCCCEEEEEECCCHHHHHHHHCCCHHHHCCCCCCCCCCCHHHCCCCCH
AMNDLQAIAEALEQEGSNHEVHVDERLRERALVPLNRMLDFAATLRG
HHHHHHHHHHHHHHCCCCCEEEHHHHHHHHHCCCHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA