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The map label for this gene is thrC [H]

Identifier: 78780194

GI number: 78780194

Start: 1707966

End: 1709069

Strand: Direct

Name: thrC [H]

Synonym: PMT9312_1808

Alternate gene names: 78780194

Gene position: 1707966-1709069 (Clockwise)

Preceding gene: 78780193

Following gene: NA

Centisome position: 99.93

GC content: 32.43

Gene sequence:

>1104_bases
ATGGTGTTATTAAATAAAATTAAGAATAAATTACGGATCAATTACAGAAAAAAAAGATGGCCTGGTCTAATTGATGCTTA
TAAACAATATCTTCCAGTTACAAAAAAAACTCCAATTATCTCACTAAACGAAGGAAATACTCCACTAATTTTTAGTGACT
CAATTAGCAAATTGATTGGAAATGGAACTAAGGTTTTTTTAAAATATGATGGTTTAAACCCTACAGGATCTTTTAAAGAT
CGGGGAATGACTATGGCCATTAGCAAAGCAAAAGAAGAAGGGCGTGAAGCTGTAATTTGTGCAAGCACTGGAAACACTTC
TGCTGCTGCTGCTGCATATGCTTCTAGAGGAGGATTAAAACCTTATGTTTTAATCCCAGAAGGATTTGTTGCACAAGGAA
AGCTTGCACAAGCTTTAATGTATGGTGCTGAGATAATATCTATTAATGGGAACTTTGATAAAGCTCTAGAAATTGTAAGA
GATTTATCTGCTGAACATCCAATAGAACTTGTTAATTCTGTTAATCCCTATCGAATACAAGGTCAAAAGACTGCAGCCTT
TGAAATTGTTGATGACTTAGGTATTGCACCTGATTGGCTTTGTATTCCAATGGGTAATGCAGGAAATATAACTGCTTATT
GGATGGGGTTTAAAGAATATTCAAAAATAAAAAGAAATTTAAAATTACCAATTATGATGGGTTTTCAATCCGAAGGCTCT
GCACCACTAGTGCAAAATATAATAATTAAAGAACCCGAGACAATTGCAACAGCAATAAGAATTGGCAATCCTGTTAATAG
AGAAAAAGCAAAAAAAGTAAAAAAAGAAAGTAAAGGAGACTTTCAATCAGTTACGGATGAAGAAATAATCAATGCTTATA
AAATACTTGCTAAAGAGGGAGTGTTTTGTGAACCTGCCAGTGCAGCATCAGTTGCTGGATTAATTAAAAATAAAAATAGA
ATTCAAAAAGAATCAACTATTGTTTGTGTTCTTACTGGAAATGGCTTGAAAGACCCTGATTGCGCTATTAATAACAATGA
TGCTATTTTCAGGAAAAATATTGAACCTTCGTTAAAAAATATAACTAAAATTTTAGGATATTAA

Upstream 100 bases:

>100_bases
CGCTTTAAGCAAAGTTATGAATAAAGTAGAATCAATTTCAGAACTATTAGACTTTTTTACAAACTCTCCTCTAGAAAAAA
TCAAAACAAATTAATGAGCT

Downstream 100 bases:

>100_bases
AAACCAAAAAAATTAGTGTCTGTGGAAATCAATTAAAAACAAAAATCATTTGTTGAAAAATATTTAAAAAGTAATTGAAT
TTGTTGATTATTTTTTTTTA

Product: threonine synthase

Products: NA

Alternate protein names: TS [H]

Number of amino acids: Translated: 367; Mature: 367

Protein sequence:

>367_residues
MVLLNKIKNKLRINYRKKRWPGLIDAYKQYLPVTKKTPIISLNEGNTPLIFSDSISKLIGNGTKVFLKYDGLNPTGSFKD
RGMTMAISKAKEEGREAVICASTGNTSAAAAAYASRGGLKPYVLIPEGFVAQGKLAQALMYGAEIISINGNFDKALEIVR
DLSAEHPIELVNSVNPYRIQGQKTAAFEIVDDLGIAPDWLCIPMGNAGNITAYWMGFKEYSKIKRNLKLPIMMGFQSEGS
APLVQNIIIKEPETIATAIRIGNPVNREKAKKVKKESKGDFQSVTDEEIINAYKILAKEGVFCEPASAASVAGLIKNKNR
IQKESTIVCVLTGNGLKDPDCAINNNDAIFRKNIEPSLKNITKILGY

Sequences:

>Translated_367_residues
MVLLNKIKNKLRINYRKKRWPGLIDAYKQYLPVTKKTPIISLNEGNTPLIFSDSISKLIGNGTKVFLKYDGLNPTGSFKD
RGMTMAISKAKEEGREAVICASTGNTSAAAAAYASRGGLKPYVLIPEGFVAQGKLAQALMYGAEIISINGNFDKALEIVR
DLSAEHPIELVNSVNPYRIQGQKTAAFEIVDDLGIAPDWLCIPMGNAGNITAYWMGFKEYSKIKRNLKLPIMMGFQSEGS
APLVQNIIIKEPETIATAIRIGNPVNREKAKKVKKESKGDFQSVTDEEIINAYKILAKEGVFCEPASAASVAGLIKNKNR
IQKESTIVCVLTGNGLKDPDCAINNNDAIFRKNIEPSLKNITKILGY
>Mature_367_residues
MVLLNKIKNKLRINYRKKRWPGLIDAYKQYLPVTKKTPIISLNEGNTPLIFSDSISKLIGNGTKVFLKYDGLNPTGSFKD
RGMTMAISKAKEEGREAVICASTGNTSAAAAAYASRGGLKPYVLIPEGFVAQGKLAQALMYGAEIISINGNFDKALEIVR
DLSAEHPIELVNSVNPYRIQGQKTAAFEIVDDLGIAPDWLCIPMGNAGNITAYWMGFKEYSKIKRNLKLPIMMGFQSEGS
APLVQNIIIKEPETIATAIRIGNPVNREKAKKVKKESKGDFQSVTDEEIINAYKILAKEGVFCEPASAASVAGLIKNKNR
IQKESTIVCVLTGNGLKDPDCAINNNDAIFRKNIEPSLKNITKILGY

Specific function: Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine [H]

COG id: COG0498

COG function: function code E; Threonine synthase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the threonine synthase family [H]

Homologues:

Organism=Escherichia coli, GI2367138, Length=283, Percent_Identity=27.9151943462898, Blast_Score=70, Evalue=3e-13,
Organism=Caenorhabditis elegans, GI17508781, Length=313, Percent_Identity=25.8785942492013, Blast_Score=74, Evalue=1e-13,
Organism=Saccharomyces cerevisiae, GI6322631, Length=313, Percent_Identity=26.517571884984, Blast_Score=73, Evalue=9e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001926
- InterPro:   IPR000634
- InterPro:   IPR004450 [H]

Pfam domain/function: PF00291 PALP [H]

EC number: =4.2.3.1 [H]

Molecular weight: Translated: 40188; Mature: 40188

Theoretical pI: Translated: 9.92; Mature: 9.92

Prosite motif: PS00165 DEHYDRATASE_SER_THR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVLLNKIKNKLRINYRKKRWPGLIDAYKQYLPVTKKTPIISLNEGNTPLIFSDSISKLIG
CEEHHHHHHHHEECCHHHCCCCHHHHHHHHCCCCCCCCEEEECCCCCCEEECCCHHHHHC
NGTKVFLKYDGLNPTGSFKDRGMTMAISKAKEEGREAVICASTGNTSAAAAAYASRGGLK
CCEEEEEEECCCCCCCCCCCCCEEEEEHHHHHCCCEEEEEEECCCCCHHHHHHHHCCCCC
PYVLIPEGFVAQGKLAQALMYGAEIISINGNFDKALEIVRDLSAEHPIELVNSVNPYRIQ
EEEECCCCCCCCHHHHHHHHHCCEEEEECCCHHHHHHHHHHCCCCCCHHHHHCCCCEEEC
GQKTAAFEIVDDLGIAPDWLCIPMGNAGNITAYWMGFKEYSKIKRNLKLPIMMGFQSEGS
CCCCHHHHHHHHCCCCCCEEEEECCCCCCEEEEEECHHHHHHHHHCCCCEEEEECCCCCC
APLVQNIIIKEPETIATAIRIGNPVNREKAKKVKKESKGDFQSVTDEEIINAYKILAKEG
CHHHHHHHHCCCHHHHHHHHCCCCCCHHHHHHHHHHCCCCHHHCCHHHHHHHHHHHHHCC
VFCEPASAASVAGLIKNKNRIQKESTIVCVLTGNGLKDPDCAINNNDAIFRKNIEPSLKN
CCCCCCCHHHHHHHHHCCHHCCCCCEEEEEEECCCCCCCCCEECCCCEEEECCCCHHHHH
ITKILGY
HHHHHCC
>Mature Secondary Structure
MVLLNKIKNKLRINYRKKRWPGLIDAYKQYLPVTKKTPIISLNEGNTPLIFSDSISKLIG
CEEHHHHHHHHEECCHHHCCCCHHHHHHHHCCCCCCCCEEEECCCCCCEEECCCHHHHHC
NGTKVFLKYDGLNPTGSFKDRGMTMAISKAKEEGREAVICASTGNTSAAAAAYASRGGLK
CCEEEEEEECCCCCCCCCCCCCEEEEEHHHHHCCCEEEEEEECCCCCHHHHHHHHCCCCC
PYVLIPEGFVAQGKLAQALMYGAEIISINGNFDKALEIVRDLSAEHPIELVNSVNPYRIQ
EEEECCCCCCCCHHHHHHHHHCCEEEEECCCHHHHHHHHHHCCCCCCHHHHHCCCCEEEC
GQKTAAFEIVDDLGIAPDWLCIPMGNAGNITAYWMGFKEYSKIKRNLKLPIMMGFQSEGS
CCCCHHHHHHHHCCCCCCEEEEECCCCCCEEEEEECHHHHHHHHHCCCCEEEEECCCCCC
APLVQNIIIKEPETIATAIRIGNPVNREKAKKVKKESKGDFQSVTDEEIINAYKILAKEG
CHHHHHHHHCCCHHHHHHHHCCCCCCHHHHHHHHHHCCCCHHHCCHHHHHHHHHHHHHCC
VFCEPASAASVAGLIKNKNRIQKESTIVCVLTGNGLKDPDCAINNNDAIFRKNIEPSLKN
CCCCCCCHHHHHHHHHCCHHCCCCCEEEEEEECCCCCCCCCEECCCCEEEECCCCHHHHH
ITKILGY
HHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8905231 [H]