Click here to switch to the map view.

The map label for this gene is mraY

Identifier: 78780187

GI number: 78780187

Start: 1697942

End: 1699018

Strand: Direct

Name: mraY

Synonym: PMT9312_1802

Alternate gene names: 78780187

Gene position: 1697942-1699018 (Clockwise)

Preceding gene: 78780186

Following gene: 78780188

Centisome position: 99.34

GC content: 25.81

Gene sequence:

>1077_bases
ATGATTGGGAAGATTAAAAAGTTTAACTTTAAATCATTATTAATATTAAATACTTTTGCTTTAATAGCTACTTCCTATTT
GTTTAATAATTTTATTTTTATAGGAGTTTACACATTATTTTTTTTTATTTCTTTATTCACAACAAAGAATGGTATAAAAA
TAATCAAAAAATTAAATTTACTTCAAAATATTAGAACTGAAGGTCCTGCTAATCACTTGAAGAAAAGTGATACACCAACA
ATGGGTGGGGTTTTTATGGTAATACCTTTTTTAATTTTTCTTTTGATAATAAATATAAATTTAGGTTCTCTAAAATTATT
CCTTTTATTACTTACTATTTTTGGTTTCTTTATTACAGGTTTTGTAGATGATTTTTTAAGCATTAAAAAAGAGCAGAATA
CAGGATTAAAAACAAAAGAAAAATTTTTCTTACAAAGTATCATTGCAATAATTTTTATATTTTTAGCCTATGAAAAAGAT
TTAATAAATCCATTAATTACAGTATCTGACTCCTGGCAAATAAATATGAACATTTTCACATTGCCAATTTCTTTTTTAGT
ATTAGTTGGCATAAGTAATTCAGTAAATTTGACTGATGGACTAGATGGATTAGCCGCTGGATGTAGTGGGATTGTCTTTT
ATGGCTTGGGAACAGAAATATTAATGAAAGAACAGCAAGAGCTAATTATTTTTAGTATTTTATGTTATTCAATGTCTGGG
ATATGTTTAGGATTTCTAAAATACAATAGTTATCCTGCAAAAATATTTATGGGTGATACAGGTTCTTTAAGTATTGGTGC
AATTCTCGGTTCTATAGCGTTATTAACCAATAGTGTTTTTACCTTATCTATTTTCTCAGGAATCTTCATTATTGAATCTT
TATCAGTAATGATTCAAGTAGGGGTTTTTAAAATTACAAAAAAATTATTTCACAATGGGAAACGCATATTTTTAATGGCA
CCACTGCACCACCATTTTGAACTTAAAGGAGTTAAGGAACAAAAAATAGTGGAAAATTTTTGGAAAATCAACATTTTGCT
TGTGATTTTAGGTATAGTTTTAAAAATCAATCTTTAA

Upstream 100 bases:

>100_bases
GAGGGAGATTCACAAGAGATTAGTACAATAGAAGAAGAAGAGCTATCAGCACTTATGGGAGAAAAAGAAGATTATAAAAC
TGAAGAAGACTCTTCAGAAG

Downstream 100 bases:

>100_bases
AAAATTTGTTATGAGTTTTTTTACATGGAAAGATAATGGATTAACGAGTGACTGCTCGAGTCTTGATGCAATGGCATCAA
GATTTGAAGAAACTGCTAAC

Product: phospho-N-acetylmuramoyl-pentapeptide- transferase

Products: NA

Alternate protein names: UDP-MurNAc-pentapeptide phosphotransferase

Number of amino acids: Translated: 358; Mature: 358

Protein sequence:

>358_residues
MIGKIKKFNFKSLLILNTFALIATSYLFNNFIFIGVYTLFFFISLFTTKNGIKIIKKLNLLQNIRTEGPANHLKKSDTPT
MGGVFMVIPFLIFLLIININLGSLKLFLLLLTIFGFFITGFVDDFLSIKKEQNTGLKTKEKFFLQSIIAIIFIFLAYEKD
LINPLITVSDSWQINMNIFTLPISFLVLVGISNSVNLTDGLDGLAAGCSGIVFYGLGTEILMKEQQELIIFSILCYSMSG
ICLGFLKYNSYPAKIFMGDTGSLSIGAILGSIALLTNSVFTLSIFSGIFIIESLSVMIQVGVFKITKKLFHNGKRIFLMA
PLHHHFELKGVKEQKIVENFWKINILLVILGIVLKINL

Sequences:

>Translated_358_residues
MIGKIKKFNFKSLLILNTFALIATSYLFNNFIFIGVYTLFFFISLFTTKNGIKIIKKLNLLQNIRTEGPANHLKKSDTPT
MGGVFMVIPFLIFLLIININLGSLKLFLLLLTIFGFFITGFVDDFLSIKKEQNTGLKTKEKFFLQSIIAIIFIFLAYEKD
LINPLITVSDSWQINMNIFTLPISFLVLVGISNSVNLTDGLDGLAAGCSGIVFYGLGTEILMKEQQELIIFSILCYSMSG
ICLGFLKYNSYPAKIFMGDTGSLSIGAILGSIALLTNSVFTLSIFSGIFIIESLSVMIQVGVFKITKKLFHNGKRIFLMA
PLHHHFELKGVKEQKIVENFWKINILLVILGIVLKINL
>Mature_358_residues
MIGKIKKFNFKSLLILNTFALIATSYLFNNFIFIGVYTLFFFISLFTTKNGIKIIKKLNLLQNIRTEGPANHLKKSDTPT
MGGVFMVIPFLIFLLIININLGSLKLFLLLLTIFGFFITGFVDDFLSIKKEQNTGLKTKEKFFLQSIIAIIFIFLAYEKD
LINPLITVSDSWQINMNIFTLPISFLVLVGISNSVNLTDGLDGLAAGCSGIVFYGLGTEILMKEQQELIIFSILCYSMSG
ICLGFLKYNSYPAKIFMGDTGSLSIGAILGSIALLTNSVFTLSIFSGIFIIESLSVMIQVGVFKITKKLFHNGKRIFLMA
PLHHHFELKGVKEQKIVENFWKINILLVILGIVLKINL

Specific function: First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan

COG id: COG0472

COG function: function code M; UDP-N-acetylmuramyl pentapeptide phosphotransferase/UDP-N-acetylglucosamine-1-phosphate transferase

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glycosyltransferase 4 family. MraY subfamily

Homologues:

Organism=Escherichia coli, GI1786275, Length=336, Percent_Identity=35.7142857142857, Blast_Score=202, Evalue=2e-53,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): MRAY_PROM9 (Q317T2)

Other databases:

- EMBL:   CP000111
- RefSeq:   YP_398299.1
- STRING:   Q317T2
- GeneID:   3766629
- GenomeReviews:   CP000111_GR
- KEGG:   pmi:PMT9312_1802
- eggNOG:   COG0472
- HOGENOM:   HBG708263
- OMA:   LRQGKGQ
- ProtClustDB:   PRK00108
- BioCyc:   PMAR74546:PMT9312_1802-MONOMER
- HAMAP:   MF_00038
- InterPro:   IPR000715
- InterPro:   IPR003524
- InterPro:   IPR018480
- PANTHER:   PTHR22926
- PANTHER:   PTHR22926:SF3
- TIGRFAMs:   TIGR00445

Pfam domain/function: PF00953 Glycos_transf_4

EC number: =2.7.8.13

Molecular weight: Translated: 40112; Mature: 40112

Theoretical pI: Translated: 10.08; Mature: 10.08

Prosite motif: PS01347 MRAY_1; PS01348 MRAY_2

Important sites: NA

Signals:

None

Transmembrane regions:

HASH(0x403fe1d4)-; HASH(0x13717430)-; HASH(0xffc8620)-; HASH(0x13311914)-; HASH(0x139201c8)-; HASH(0x1384787c)-; HASH(0x139414a4)-; HASH(0x137f84d4)-; HASH(0x139621fc)-;

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIGKIKKFNFKSLLILNTFALIATSYLFNNFIFIGVYTLFFFISLFTTKNGIKIIKKLNL
CCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHH
LQNIRTEGPANHLKKSDTPTMGGVFMVIPFLIFLLIININLGSLKLFLLLLTIFGFFITG
HHHHCCCCCHHHCCCCCCCCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHH
FVDDFLSIKKEQNTGLKTKEKFFLQSIIAIIFIFLAYEKDLINPLITVSDSWQINMNIFT
HHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEECCCEEEEEEEEE
LPISFLVLVGISNSVNLTDGLDGLAAGCSGIVFYGLGTEILMKEQQELIIFSILCYSMSG
HHHHHHHHHHCCCCCCCCCCCHHHHHCCCCEEEECCCHHHHHHHHHHHHHHHHHHHHHHH
ICLGFLKYNSYPAKIFMGDTGSLSIGAILGSIALLTNSVFTLSIFSGIFIIESLSVMIQV
HHHHHHHCCCCCCEEEECCCCCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHH
GVFKITKKLFHNGKRIFLMAPLHHHFELKGVKEQKIVENFWKINILLVILGIVLKINL
HHHHHHHHHHHCCCEEEEECCCCCCEEECCCCHHHHHHHHHHHHHHHHHHHHHHEECH
>Mature Secondary Structure
MIGKIKKFNFKSLLILNTFALIATSYLFNNFIFIGVYTLFFFISLFTTKNGIKIIKKLNL
CCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHH
LQNIRTEGPANHLKKSDTPTMGGVFMVIPFLIFLLIININLGSLKLFLLLLTIFGFFITG
HHHHCCCCCHHHCCCCCCCCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHH
FVDDFLSIKKEQNTGLKTKEKFFLQSIIAIIFIFLAYEKDLINPLITVSDSWQINMNIFT
HHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEECCCEEEEEEEEE
LPISFLVLVGISNSVNLTDGLDGLAAGCSGIVFYGLGTEILMKEQQELIIFSILCYSMSG
HHHHHHHHHHCCCCCCCCCCCHHHHHCCCCEEEECCCHHHHHHHHHHHHHHHHHHHHHHH
ICLGFLKYNSYPAKIFMGDTGSLSIGAILGSIALLTNSVFTLSIFSGIFIIESLSVMIQV
HHHHHHHCCCCCCEEEECCCCCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHH
GVFKITKKLFHNGKRIFLMAPLHHHFELKGVKEQKIVENFWKINILLVILGIVLKINL
HHHHHHHHHHHCCCEEEEECCCCCCEEECCCCHHHHHHHHHHHHHHHHHHHHHHEECH

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA