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The map label for this gene is yycF [H]

Identifier: 78780097

GI number: 78780097

Start: 1600804

End: 1601550

Strand: Reverse

Name: yycF [H]

Synonym: PMT9312_1712

Alternate gene names: 78780097

Gene position: 1601550-1600804 (Counterclockwise)

Preceding gene: 78780098

Following gene: 78780096

Centisome position: 93.7

GC content: 38.69

Gene sequence:

>747_bases
ATGTCAAAAGCAAGAATTTTAGTTGTTGATGATGAACCTGCAGTTTTGAAGGTATTAGTTACAAGGCTTCAACTAGCAGG
ATATCAAGTTTTTTCAGCCACTAACGGCGAAGAAGCTATTGAATCTTTTCACAGGGATTCCCCAGATTTGATAGTTCTTG
ATGTTATGCTTCCAAAAATGGATGGATTCGCAGTTTGCAGAAGAATTAGAGCTGAATCAGTAGTGCCAATAATATTCTTA
ACCGCTCTAGAGGCTATTTCAGAAAGAGTTGCAGGTTTGGACTTAGGTGCTGATGATTACTTATCTAAACCATTTAGCCC
AAAAGAATTAGAGGCTAGGATAGCTACTATTTTGAGAAGAATGGGACCTACTGTATCGGTTGCTGAAACTAAAGAAGTTC
CATCTGGCAAAGGAGTTATGAAATTTGGAAGTTTAGTTGTTGATACTAATCGTCGACAAGTTTCTAGAGCAGGGGAAAGA
ATTAGTCTAACTTATACTGAATTTAGCCTCTTAGAATTATTATTCGACGAGCCTGGTAAAGTTGTTCCTCGAGCAGAAAT
TTTAGAACAGCTATGGGGTTATCCGCCTCGTAGAGCTGCAGATTTAAGAGTTGTAGATGTATATGTCGCAAGACTAAGGG
GTAAATTGGAACCAGATCCAAGAAATCCAGAATTAATATTAACTGTTAGAGGGATCGGTTATGCGTCTCAGAGAGTTGGC
GAAACAGCAACATCTTTGGCAAGTTGA

Upstream 100 bases:

>100_bases
TATCCCTTTGAGGGTTCGTAATGTTATATTTTTAATTGTTAGAATAAATATTCAATGCAATAATTCTTTGCTTTGAAATA
TTGAGAAATTTTTTTGAACT

Downstream 100 bases:

>100_bases
GCCATAGTCTGATAATTTTATTAAATAAAACAAATATATTAAAATAAATTTTGTCTGAAATAAGAGAAGCACGCTTACAA
AAAGCTAATTCACTAGTTAG

Product: two component transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 248; Mature: 247

Protein sequence:

>248_residues
MSKARILVVDDEPAVLKVLVTRLQLAGYQVFSATNGEEAIESFHRDSPDLIVLDVMLPKMDGFAVCRRIRAESVVPIIFL
TALEAISERVAGLDLGADDYLSKPFSPKELEARIATILRRMGPTVSVAETKEVPSGKGVMKFGSLVVDTNRRQVSRAGER
ISLTYTEFSLLELLFDEPGKVVPRAEILEQLWGYPPRRAADLRVVDVYVARLRGKLEPDPRNPELILTVRGIGYASQRVG
ETATSLAS

Sequences:

>Translated_248_residues
MSKARILVVDDEPAVLKVLVTRLQLAGYQVFSATNGEEAIESFHRDSPDLIVLDVMLPKMDGFAVCRRIRAESVVPIIFL
TALEAISERVAGLDLGADDYLSKPFSPKELEARIATILRRMGPTVSVAETKEVPSGKGVMKFGSLVVDTNRRQVSRAGER
ISLTYTEFSLLELLFDEPGKVVPRAEILEQLWGYPPRRAADLRVVDVYVARLRGKLEPDPRNPELILTVRGIGYASQRVG
ETATSLAS
>Mature_247_residues
SKARILVVDDEPAVLKVLVTRLQLAGYQVFSATNGEEAIESFHRDSPDLIVLDVMLPKMDGFAVCRRIRAESVVPIIFLT
ALEAISERVAGLDLGADDYLSKPFSPKELEARIATILRRMGPTVSVAETKEVPSGKGVMKFGSLVVDTNRRQVSRAGERI
SLTYTEFSLLELLFDEPGKVVPRAEILEQLWGYPPRRAADLRVVDVYVARLRGKLEPDPRNPELILTVRGIGYASQRVGE
TATSLAS

Specific function: Member of the two-component regulatory system YycG/YycF involved in the regulation of the ftsAZ operon, the yocH, ykvT, cwlO, lytE, ydjM, yjeA, yoeB genes and the tagAB and tagDEF operons. Probably phosphorylates YycF. Binds to the ftsAZ P1 promoter seque

COG id: COG0745

COG function: function code TK; Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1786784, Length=231, Percent_Identity=42.4242424242424, Blast_Score=158, Evalue=3e-40,
Organism=Escherichia coli, GI1788394, Length=231, Percent_Identity=38.961038961039, Blast_Score=151, Evalue=3e-38,
Organism=Escherichia coli, GI1786911, Length=229, Percent_Identity=39.3013100436681, Blast_Score=149, Evalue=2e-37,
Organism=Escherichia coli, GI1789809, Length=231, Percent_Identity=38.5281385281385, Blast_Score=147, Evalue=7e-37,
Organism=Escherichia coli, GI1786599, Length=233, Percent_Identity=36.480686695279, Blast_Score=140, Evalue=1e-34,
Organism=Escherichia coli, GI87082012, Length=231, Percent_Identity=36.3636363636364, Blast_Score=138, Evalue=3e-34,
Organism=Escherichia coli, GI1790863, Length=235, Percent_Identity=32.7659574468085, Blast_Score=134, Evalue=4e-33,
Organism=Escherichia coli, GI1790860, Length=240, Percent_Identity=34.5833333333333, Blast_Score=132, Evalue=2e-32,
Organism=Escherichia coli, GI1787375, Length=232, Percent_Identity=35.7758620689655, Blast_Score=126, Evalue=2e-30,
Organism=Escherichia coli, GI1789402, Length=231, Percent_Identity=35.4978354978355, Blast_Score=125, Evalue=3e-30,
Organism=Escherichia coli, GI1790552, Length=231, Percent_Identity=33.7662337662338, Blast_Score=122, Evalue=3e-29,
Organism=Escherichia coli, GI2367329, Length=231, Percent_Identity=37.6623376623377, Blast_Score=121, Evalue=5e-29,
Organism=Escherichia coli, GI1787229, Length=232, Percent_Identity=33.1896551724138, Blast_Score=119, Evalue=2e-28,
Organism=Escherichia coli, GI145693140, Length=232, Percent_Identity=34.9137931034483, Blast_Score=110, Evalue=1e-25,
Organism=Escherichia coli, GI1788550, Length=107, Percent_Identity=38.3177570093458, Blast_Score=82, Evalue=3e-17,
Organism=Escherichia coli, GI1790437, Length=134, Percent_Identity=34.3283582089552, Blast_Score=70, Evalue=1e-13,
Organism=Escherichia coli, GI1790299, Length=110, Percent_Identity=33.6363636363636, Blast_Score=70, Evalue=1e-13,
Organism=Escherichia coli, GI145693157, Length=102, Percent_Identity=36.2745098039216, Blast_Score=68, Evalue=7e-13,
Organism=Escherichia coli, GI1788713, Length=116, Percent_Identity=36.2068965517241, Blast_Score=65, Evalue=3e-12,
Organism=Escherichia coli, GI1789149, Length=202, Percent_Identity=27.7227722772277, Blast_Score=64, Evalue=7e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR001867
- InterPro:   IPR001789
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00072 Response_reg; PF00486 Trans_reg_C [H]

EC number: NA

Molecular weight: Translated: 27364; Mature: 27233

Theoretical pI: Translated: 6.09; Mature: 6.09

Prosite motif: PS50110 RESPONSE_REGULATORY

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSKARILVVDDEPAVLKVLVTRLQLAGYQVFSATNGEEAIESFHRDSPDLIVLDVMLPKM
CCCCEEEEECCCCHHHHHHHHHHHHHCEEEEECCCHHHHHHHHHCCCCCEEEEEEECCCC
DGFAVCRRIRAESVVPIIFLTALEAISERVAGLDLGADDYLSKPFSPKELEARIATILRR
CHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCCCCHHHHCCCCCHHHHHHHHHHHHHH
MGPTVSVAETKEVPSGKGVMKFGSLVVDTNRRQVSRAGERISLTYTEFSLLELLFDEPGK
HCCCEEEHHCCCCCCCCCHHHHCCEEEECCHHHHHHCCCEEEEEEHHHHHHHHHHCCCCC
VVPRAEILEQLWGYPPRRAADLRVVDVYVARLRGKLEPDPRNPELILTVRGIGYASQRVG
CCCHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHCCCCCCCCCCEEEEEEECCCHHHHHHH
ETATSLAS
HHHHHHCC
>Mature Secondary Structure 
SKARILVVDDEPAVLKVLVTRLQLAGYQVFSATNGEEAIESFHRDSPDLIVLDVMLPKM
CCCEEEEECCCCHHHHHHHHHHHHHCEEEEECCCHHHHHHHHHCCCCCEEEEEEECCCC
DGFAVCRRIRAESVVPIIFLTALEAISERVAGLDLGADDYLSKPFSPKELEARIATILRR
CHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCCCCHHHHCCCCCHHHHHHHHHHHHHH
MGPTVSVAETKEVPSGKGVMKFGSLVVDTNRRQVSRAGERISLTYTEFSLLELLFDEPGK
HCCCEEEHHCCCCCCCCCHHHHCCEEEECCHHHHHHCCCEEEEEEHHHHHHHHHHCCCCC
VVPRAEILEQLWGYPPRRAADLRVVDVYVARLRGKLEPDPRNPELILTVRGIGYASQRVG
CCCHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHCCCCCCCCCCEEEEEEECCCHHHHHHH
ETATSLAS
HHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7584024; 9384377; 9829949; 10878122 [H]