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The map label for this gene is wzb [C]

Identifier: 78780068

GI number: 78780068

Start: 1572658

End: 1573131

Strand: Reverse

Name: wzb [C]

Synonym: PMT9312_1683

Alternate gene names: 78780068

Gene position: 1573131-1572658 (Counterclockwise)

Preceding gene: 78780069

Following gene: 78780066

Centisome position: 92.04

GC content: 33.97

Gene sequence:

>474_bases
ATGAAAAAAATTTCTGTTCTTTTTGTATGTTTGGGAAATATTTGTAGGTCTCCTGCAGCAGAAGCTATTTTTATAAGTCT
ACTTGAAAGGAAAGGATTAACCGATGGCTTTATTGTAGATTCTGCTGGAACTGGGAGTTGGCATATTGGGAAAAAAGCTG
ACTCTAGGATGAGAATTGCTGCAGAAAGAAGAGACATAAATATCTTAAGTAGGGCTCGTCAAATTACTAGCAAAGATTTT
GAGGAATTTAACTATATTCTTGCGATGGACGACTCAAATTTTCGAAATATTCAAGATCTTAAAAAGAGAACATCTTCAAC
TGATTTTGCATCAATTAAAAAAATTCAAGATTTTAGATCAGTTTTTAATGAGCAAGAAGTTCCTGACCCCTATTTTGGAG
GTGATGACGGCTTTGATTATGTTCTTGATATATTAGAAGATTCTGTGAGCGGCTTTTTGGAAAGTATGTCTTGA

Upstream 100 bases:

>100_bases
TGTTATCCAGTTTGTTTGGTAAGGAATTTACTGAATCTTTAATTAAAGAAGTTTTATTTACTACTTAAACATCTTATAAT
TTTATAAAAGGTGAGATGAT

Downstream 100 bases:

>100_bases
ATTTATCGGATCTGAGTCTCTTTAGGGATCTTGTCATTATAAAGATCAATAATTTTATCTACTACCTCATTAATTGAACA
TCCATCCGTAATAATTTCTA

Product: protein tyrosine phosphatase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 157; Mature: 157

Protein sequence:

>157_residues
MKKISVLFVCLGNICRSPAAEAIFISLLERKGLTDGFIVDSAGTGSWHIGKKADSRMRIAAERRDINILSRARQITSKDF
EEFNYILAMDDSNFRNIQDLKKRTSSTDFASIKKIQDFRSVFNEQEVPDPYFGGDDGFDYVLDILEDSVSGFLESMS

Sequences:

>Translated_157_residues
MKKISVLFVCLGNICRSPAAEAIFISLLERKGLTDGFIVDSAGTGSWHIGKKADSRMRIAAERRDINILSRARQITSKDF
EEFNYILAMDDSNFRNIQDLKKRTSSTDFASIKKIQDFRSVFNEQEVPDPYFGGDDGFDYVLDILEDSVSGFLESMS
>Mature_157_residues
MKKISVLFVCLGNICRSPAAEAIFISLLERKGLTDGFIVDSAGTGSWHIGKKADSRMRIAAERRDINILSRARQITSKDF
EEFNYILAMDDSNFRNIQDLKKRTSSTDFASIKKIQDFRSVFNEQEVPDPYFGGDDGFDYVLDILEDSVSGFLESMS

Specific function: Dephosphorylates Wzc. Required For The Extracellular Polysaccharide Colanic Acid Synthesis. Probably Involved In The Export Of Colanic Acid From The Cell To Medium. [C]

COG id: COG0394

COG function: function code T; Protein-tyrosine-phosphatase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the low molecular weight phosphotyrosine protein phosphatase family [H]

Homologues:

Organism=Homo sapiens, GI6005988, Length=153, Percent_Identity=37.2549019607843, Blast_Score=111, Evalue=3e-25,
Organism=Homo sapiens, GI4757714, Length=153, Percent_Identity=39.8692810457516, Blast_Score=109, Evalue=1e-24,
Organism=Homo sapiens, GI96304457, Length=77, Percent_Identity=45.4545454545455, Blast_Score=71, Evalue=5e-13,
Organism=Saccharomyces cerevisiae, GI6325330, Length=141, Percent_Identity=35.4609929078014, Blast_Score=96, Evalue=2e-21,
Organism=Drosophila melanogaster, GI78706766, Length=150, Percent_Identity=34, Blast_Score=96, Evalue=1e-20,
Organism=Drosophila melanogaster, GI78706768, Length=150, Percent_Identity=34, Blast_Score=96, Evalue=1e-20,
Organism=Drosophila melanogaster, GI78711846, Length=153, Percent_Identity=35.2941176470588, Blast_Score=94, Evalue=3e-20,
Organism=Drosophila melanogaster, GI78706770, Length=155, Percent_Identity=34.1935483870968, Blast_Score=94, Evalue=4e-20,
Organism=Drosophila melanogaster, GI78706772, Length=155, Percent_Identity=34.1935483870968, Blast_Score=94, Evalue=4e-20,
Organism=Drosophila melanogaster, GI78706764, Length=127, Percent_Identity=37.007874015748, Blast_Score=93, Evalue=7e-20,
Organism=Drosophila melanogaster, GI24648069, Length=92, Percent_Identity=35.8695652173913, Blast_Score=66, Evalue=8e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000106
- InterPro:   IPR017867 [H]

Pfam domain/function: PF01451 LMWPc [H]

EC number: =3.1.3.48 [H]

Molecular weight: Translated: 17723; Mature: 17723

Theoretical pI: Translated: 4.85; Mature: 4.85

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKKISVLFVCLGNICRSPAAEAIFISLLERKGLTDGFIVDSAGTGSWHIGKKADSRMRIA
CCHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCCEEEECCCCCCEECCCCCCCHHHHH
AERRDINILSRARQITSKDFEEFNYILAMDDSNFRNIQDLKKRTSSTDFASIKKIQDFRS
HHHHHHHHHHHHHHHHHHHHHHCCEEEEECCCCCCHHHHHHHHCCCCHHHHHHHHHHHHH
VFNEQEVPDPYFGGDDGFDYVLDILEDSVSGFLESMS
HHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MKKISVLFVCLGNICRSPAAEAIFISLLERKGLTDGFIVDSAGTGSWHIGKKADSRMRIA
CCHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCCEEEECCCCCCEECCCCCCCHHHHH
AERRDINILSRARQITSKDFEEFNYILAMDDSNFRNIQDLKKRTSSTDFASIKKIQDFRS
HHHHHHHHHHHHHHHHHHHHHHCCEEEEECCCCCCHHHHHHHHCCCCHHHHHHHHHHHHH
VFNEQEVPDPYFGGDDGFDYVLDILEDSVSGFLESMS
HHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8590279; 8905231 [H]