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The map label for this gene is moeZ [H]

Identifier: 78780046

GI number: 78780046

Start: 1548452

End: 1549594

Strand: Direct

Name: moeZ [H]

Synonym: PMT9312_1661

Alternate gene names: 78780046

Gene position: 1548452-1549594 (Clockwise)

Preceding gene: 78780044

Following gene: 78780048

Centisome position: 90.59

GC content: 30.45

Gene sequence:

>1143_bases
ATGTCCAAAGATATCAAATTTAATTGCCTAAACTCAGATGAAGAAGAAAGATATCAAAAACATTTAACTCTCAAAGAAAT
AGGTTATGAGGGTCAAATAGATATTAAAAACAGTTCAGTATTATGTATTGGCGCAGGCGGGCTTGGATCTTCTGTTTTAC
TTTACCTGACGGCATCAGGAATTGGAGAAATTGGAATAGTAGATAATGATCACGTTGAGAAGTCTAATCTACAAAGACAG
ATAATCCATGAAACAAATAATATTGGTAATCTTAAAATTGATTCTGCACGGGAAAGAATGAGAAAATTGAATCCTAATTC
TAAATTAATAACTTTTGCTGAAAGAATTAATCCTAAAAATGCCCTAGAAATAATTCGACAATTTGATATTATTTGTGATT
GCTCAGATAACTTTAGCACTAGATATTTGATAAACGATGCGTGTCTGATACTAAAGAAACCTCTAGTCTTTGGCAGTGTA
CAAGGATTTGAAGGGCAAGTAAGTGTTTTTAATTTACACGAAAAGAGTCCTAATTTAAGAGACTTGCTTCCAGAATCACC
CTCAAAAAATAATGTTCCCAGTTGTGCGGAATATGGGGTCGTGGGAGTTTCAACAGGTCTAATAGGCATTCTTCAAGTGA
ATGAGATAATTAAAATCATTTTAAAAAAAGGTGAAATTTTAGATGGGAAAATTTTGATTTTTGATCTCTTGAATATGAAT
ATGAAAAAATTAAATCTAAAAGGTGATCAAATAAATAAGCGAATCAAAAATCTTTCTCAGTTTGTGGACTTTTATTGTGA
AGATGAATGTTCTGATAAAAATAAAATCAACAGAATCAATGCTAATGATTTTAATAGCTTATACAAAGCAAAACCCAACA
AAATTCTTTTAATTGATGTTAGGGAAAATGAAGAATTTTCTAATTCTGCAATAGAGGGTTCTATATCAATTCCCCTAAGT
CATTTGAGCCAAAAGCCTGACTTAGAATTTATTCAAAAAGAAAGTTTAATTAAAGAGGTTTTCACTATATGCAAATCGGG
GAAACGTTCTGAAAAAGCTTCCAAAATCTTGTCTAAATTCAAAATTAAATCGAGATCTATTGAAGGTGGCATTGAAAAGG
TAAAAAAATTATTATGCAATTAA

Upstream 100 bases:

>100_bases
ACATGAAAAAAATTAAGTAATAGGAGATTTTAAAAAGGCTAAAATTTTTATTTTAATTATTATATTTTCATAGTTAATTT
TGCATAATTAAAGAATCGAT

Downstream 100 bases:

>100_bases
TATTTCAAAAATATTTAGTAATCTACCCCTCTTTTTAAATCAACTCCAACATTTGCATAATGCTTATGACAGACCATTTC
AGAGTAAATATCAGCAAGTT

Product: rhodanese-like protein

Products: NA

Alternate protein names: Sulfur carrier protein CysO adenylyltransferase; Sulfur carrier protein CysO sulfurtransferase [H]

Number of amino acids: Translated: 380; Mature: 379

Protein sequence:

>380_residues
MSKDIKFNCLNSDEEERYQKHLTLKEIGYEGQIDIKNSSVLCIGAGGLGSSVLLYLTASGIGEIGIVDNDHVEKSNLQRQ
IIHETNNIGNLKIDSARERMRKLNPNSKLITFAERINPKNALEIIRQFDIICDCSDNFSTRYLINDACLILKKPLVFGSV
QGFEGQVSVFNLHEKSPNLRDLLPESPSKNNVPSCAEYGVVGVSTGLIGILQVNEIIKIILKKGEILDGKILIFDLLNMN
MKKLNLKGDQINKRIKNLSQFVDFYCEDECSDKNKINRINANDFNSLYKAKPNKILLIDVRENEEFSNSAIEGSISIPLS
HLSQKPDLEFIQKESLIKEVFTICKSGKRSEKASKILSKFKIKSRSIEGGIEKVKKLLCN

Sequences:

>Translated_380_residues
MSKDIKFNCLNSDEEERYQKHLTLKEIGYEGQIDIKNSSVLCIGAGGLGSSVLLYLTASGIGEIGIVDNDHVEKSNLQRQ
IIHETNNIGNLKIDSARERMRKLNPNSKLITFAERINPKNALEIIRQFDIICDCSDNFSTRYLINDACLILKKPLVFGSV
QGFEGQVSVFNLHEKSPNLRDLLPESPSKNNVPSCAEYGVVGVSTGLIGILQVNEIIKIILKKGEILDGKILIFDLLNMN
MKKLNLKGDQINKRIKNLSQFVDFYCEDECSDKNKINRINANDFNSLYKAKPNKILLIDVRENEEFSNSAIEGSISIPLS
HLSQKPDLEFIQKESLIKEVFTICKSGKRSEKASKILSKFKIKSRSIEGGIEKVKKLLCN
>Mature_379_residues
SKDIKFNCLNSDEEERYQKHLTLKEIGYEGQIDIKNSSVLCIGAGGLGSSVLLYLTASGIGEIGIVDNDHVEKSNLQRQI
IHETNNIGNLKIDSARERMRKLNPNSKLITFAERINPKNALEIIRQFDIICDCSDNFSTRYLINDACLILKKPLVFGSVQ
GFEGQVSVFNLHEKSPNLRDLLPESPSKNNVPSCAEYGVVGVSTGLIGILQVNEIIKIILKKGEILDGKILIFDLLNMNM
KKLNLKGDQINKRIKNLSQFVDFYCEDECSDKNKINRINANDFNSLYKAKPNKILLIDVRENEEFSNSAIEGSISIPLSH
LSQKPDLEFIQKESLIKEVFTICKSGKRSEKASKILSKFKIKSRSIEGGIEKVKKLLCN

Specific function: Catalyzes the conversion of the sulfur carrier protein CysO to CysO-thiocarboxylate. The reaction is thought to proceed in two steps:first, ATP-dependent activation of CysO as acyl- adenylate (CysO-COOAMP), followed by sulfur transfer to give CysO- thioca

COG id: COG0476

COG function: function code H; Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2

Gene ontology:

Cell location: Membrane; Single-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 rhodanese domain [H]

Homologues:

Organism=Homo sapiens, GI7657339, Length=395, Percent_Identity=33.1645569620253, Blast_Score=211, Evalue=9e-55,
Organism=Homo sapiens, GI4885649, Length=168, Percent_Identity=28.5714285714286, Blast_Score=85, Evalue=1e-16,
Organism=Homo sapiens, GI23510338, Length=208, Percent_Identity=25.4807692307692, Blast_Score=76, Evalue=6e-14,
Organism=Homo sapiens, GI23510340, Length=208, Percent_Identity=25.4807692307692, Blast_Score=76, Evalue=6e-14,
Organism=Homo sapiens, GI38045948, Length=163, Percent_Identity=26.9938650306748, Blast_Score=72, Evalue=7e-13,
Organism=Homo sapiens, GI38045942, Length=177, Percent_Identity=30.5084745762712, Blast_Score=67, Evalue=2e-11,
Organism=Homo sapiens, GI38045944, Length=177, Percent_Identity=30.5084745762712, Blast_Score=67, Evalue=2e-11,
Organism=Escherichia coli, GI1787048, Length=237, Percent_Identity=32.9113924050633, Blast_Score=152, Evalue=3e-38,
Organism=Escherichia coli, GI87082356, Length=240, Percent_Identity=35, Blast_Score=132, Evalue=3e-32,
Organism=Caenorhabditis elegans, GI17540406, Length=395, Percent_Identity=31.8987341772152, Blast_Score=200, Evalue=9e-52,
Organism=Caenorhabditis elegans, GI193203301, Length=136, Percent_Identity=30.1470588235294, Blast_Score=72, Evalue=4e-13,
Organism=Saccharomyces cerevisiae, GI6321903, Length=392, Percent_Identity=33.1632653061224, Blast_Score=197, Evalue=3e-51,
Organism=Saccharomyces cerevisiae, GI6320598, Length=141, Percent_Identity=33.3333333333333, Blast_Score=74, Evalue=4e-14,
Organism=Saccharomyces cerevisiae, GI6322639, Length=194, Percent_Identity=28.3505154639175, Blast_Score=73, Evalue=9e-14,
Organism=Saccharomyces cerevisiae, GI6325438, Length=166, Percent_Identity=27.710843373494, Blast_Score=69, Evalue=1e-12,
Organism=Drosophila melanogaster, GI24582879, Length=389, Percent_Identity=34.1902313624679, Blast_Score=234, Evalue=6e-62,
Organism=Drosophila melanogaster, GI24660640, Length=136, Percent_Identity=33.0882352941176, Blast_Score=86, Evalue=3e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR007901
- InterPro:   IPR009036
- InterPro:   IPR016040
- InterPro:   IPR001763
- InterPro:   IPR000594 [H]

Pfam domain/function: PF05237 MoeZ_MoeB; PF00581 Rhodanese; PF00899 ThiF [H]

EC number: NA

Molecular weight: Translated: 42696; Mature: 42565

Theoretical pI: Translated: 8.53; Mature: 8.53

Prosite motif: PS50206 RHODANESE_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.6 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
2.6 %Cys     (Mature Protein)
0.8 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSKDIKFNCLNSDEEERYQKHLTLKEIGYEGQIDIKNSSVLCIGAGGLGSSVLLYLTASG
CCCCCEEEECCCCHHHHHHHHCHHHHCCCCCEEEECCCCEEEEECCCCCCCEEEEEEECC
IGEIGIVDNDHVEKSNLQRQIIHETNNIGNLKIDSARERMRKLNPNSKLITFAERINPKN
CCEEECCCCCCCCHHHHHHHHHHHCCCCCCEEEHHHHHHHHHCCCCCCEEEHHHHCCHHH
ALEIIRQFDIICDCSDNFSTRYLINDACLILKKPLVFGSVQGFEGQVSVFNLHEKSPNLR
HHHHHHHHCEEEECCCCCCEEEEECCCEEEHCCCHHEECCCCCCCCEEEEEECCCCCCHH
DLLPESPSKNNVPSCAEYGVVGVSTGLIGILQVNEIIKIILKKGEILDGKILIFDLLNMN
HHCCCCCCCCCCCCHHHCCEEEECCCHHHHHHHHHHHHHHHHCCCCCCCCEEEEEHHCCC
MKKLNLKGDQINKRIKNLSQFVDFYCEDECSDKNKINRINANDFNSLYKAKPNKILLIDV
CEEECCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHHCCCCEEEEEEE
RENEEFSNSAIEGSISIPLSHLSQKPDLEFIQKESLIKEVFTICKSGKRSEKASKILSKF
CCCCCCCCCCCCCEEECCHHHCCCCCCHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHH
KIKSRSIEGGIEKVKKLLCN
HHHHCCHHHHHHHHHHHHCC
>Mature Secondary Structure 
SKDIKFNCLNSDEEERYQKHLTLKEIGYEGQIDIKNSSVLCIGAGGLGSSVLLYLTASG
CCCCEEEECCCCHHHHHHHHCHHHHCCCCCEEEECCCCEEEEECCCCCCCEEEEEEECC
IGEIGIVDNDHVEKSNLQRQIIHETNNIGNLKIDSARERMRKLNPNSKLITFAERINPKN
CCEEECCCCCCCCHHHHHHHHHHHCCCCCCEEEHHHHHHHHHCCCCCCEEEHHHHCCHHH
ALEIIRQFDIICDCSDNFSTRYLINDACLILKKPLVFGSVQGFEGQVSVFNLHEKSPNLR
HHHHHHHHCEEEECCCCCCEEEEECCCEEEHCCCHHEECCCCCCCCEEEEEECCCCCCHH
DLLPESPSKNNVPSCAEYGVVGVSTGLIGILQVNEIIKIILKKGEILDGKILIFDLLNMN
HHCCCCCCCCCCCCHHHCCEEEECCCHHHHHHHHHHHHHHHHCCCCCCCCEEEEEHHCCC
MKKLNLKGDQINKRIKNLSQFVDFYCEDECSDKNKINRINANDFNSLYKAKPNKILLIDV
CEEECCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHHCCCCEEEEEEE
RENEEFSNSAIEGSISIPLSHLSQKPDLEFIQKESLIKEVFTICKSGKRSEKASKILSKF
CCCCCCCCCCCCCEEECCHHHCCCCCCHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHH
KIKSRSIEGGIEKVKKLLCN
HHHHCCHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9634230; 12218036 [H]