Click here to switch to the map view.

The map label for this gene is dnaK [H]

Identifier: 78779909

GI number: 78779909

Start: 1421597

End: 1423165

Strand: Direct

Name: dnaK [H]

Synonym: PMT9312_1525

Alternate gene names: 78779909

Gene position: 1421597-1423165 (Clockwise)

Preceding gene: 78779905

Following gene: 78779911

Centisome position: 83.17

GC content: 29.38

Gene sequence:

>1569_bases
ATGGAAGAAAATTTATCTGGAACTCTTGCTATTGATCTAGGAAATACTAATACCGTAGTCGCTTTTCAAGATGAAAAAGA
TATAAACACTATATTAGTTGAAATCCCGAATATTACATCATCTCCTGGAGTTATCCCTACAGCAGTTTGGTTCGAGAAAC
CTTCAGAAATTTTGAAAATTGGTGACAGTGCTTTAAAGATGATAAATAGCTCTAATTCAGAATTATTTTTTCATTCGAAT
TTTAAAAGATTAATTGGAAATCCTGTTGAAAAAATTAATCAGAAAAATATTTTAAGCCCTACTGAATGTGGCGAAAAATT
TTTTAAATTTTTGTGGGCAAACATTCCTCAAAAATATAAAATTAAGAGACTTGTTTTAACTGCTCCTATTGACACATACA
AGGGTTACAGAGAATGGTTAGTTAACCTTTGTGAGGAAATATCTGTAGATGAAATAGCGCTAGTTGATGAACCTACTGCC
GCAAGTTTAGGGATAAATGTACCATTTGGCTCGAAAATTATGACACTAGATATTGGAGGAAGCACAATAGATATGAATAT
AGTCAAAATAGAAGGGGGAGAAGGTAAATCTGATCCTATAGCTGAATTATTAAAATTTAAAGGAAATAATGTAAGTTCAA
TTTCAAAACAAAAAGTAAGATGTGCTGAAATCATTAGTAAAAGTGGCTCGAAAATTGGTGGTAAAGATATTGATCAATGG
ATTGTTGATTTTTTTATACCTGATAATAAATATCCAATTAATCTTTTAAAGGCAGAAGTAATTAAATGTAAACTAAGTTC
ATCTGCAATTAAAGATGACAATAAATATCCAACAAAACTTTTAACTGAAGGACATCAAGAAAAAGAATTTTTCCTAAGTA
GAGAAACCTTTGAGAAAATTATTATTGAGAATAATCTTCTTAATCACCTTAACTCCTTACTTAAAGATTTATTAAATGAA
GCAAGAGGCAAATATTGCACAGTAGATGATTTAAGTGCAATCATTTTGGTTGGAGGGGGTACTCAAATACCATTAATTAA
AGAATGGATAGCAAAAAAGATTCCAAAAATTCATATAAAGTCGCCACCTCCAATTGAATCAATAGCATTAGGAGCTTTAG
CAATGACTCCAGGAGTAAAAATTAAAGATATCTTAAACAAAGGATTATCAATAAGGTTATTAAATAAAAGAGAACAAACA
CACTTCTGGCATCCAATTTTTTGCAAAGGCCAAACATGGCCTACTGAAAACCCATTTAAATTAATTCTTCAAGCCAGTAA
AATTAATCAGAAAATATTTGAAATAATTATTGGAGAAACAAAAAAAGACAGGGAGTATGATGTGATTTTTGAAAATGGAT
TACCAAAATTATCCGAGATTCAAAGTGAAGAAGAAATTATTAGATGGGACAAAAAACCACTCAAAATCTTACTAAAAAAT
AGTTCTAATATTGGAGAAGATAACTTAATACTTTTCTTCAAAATCAACAAAAAAGCTGATTTGCTAGTTAAGTGTTTTGA
TATTCAAGATGAATTTTTAGGGGAATATAATTTAGGAAATATCTACTAA

Upstream 100 bases:

>100_bases
TCATTAAAAATTTTTTTTAATATATTATGTATCTTACAGTTTATTGGAACGATTCAAAATATAAATTACAAAAAGAACTT
AATTGATTCAAAAAATTCAT

Downstream 100 bases:

>100_bases
CTTATAGCTATTCAAGAAAAACTCCTTCTTCATTATCAACATTATTAAGACGTAAACTAATACTTTCATTTTTACTAGTT
GGAACTCTTTTACCGCAAAA

Product: HSP70 family molecular chaperone

Products: NA

Alternate protein names: HSP70; Heat shock 70 kDa protein; Heat shock protein 70 [H]

Number of amino acids: Translated: 522; Mature: 522

Protein sequence:

>522_residues
MEENLSGTLAIDLGNTNTVVAFQDEKDINTILVEIPNITSSPGVIPTAVWFEKPSEILKIGDSALKMINSSNSELFFHSN
FKRLIGNPVEKINQKNILSPTECGEKFFKFLWANIPQKYKIKRLVLTAPIDTYKGYREWLVNLCEEISVDEIALVDEPTA
ASLGINVPFGSKIMTLDIGGSTIDMNIVKIEGGEGKSDPIAELLKFKGNNVSSISKQKVRCAEIISKSGSKIGGKDIDQW
IVDFFIPDNKYPINLLKAEVIKCKLSSSAIKDDNKYPTKLLTEGHQEKEFFLSRETFEKIIIENNLLNHLNSLLKDLLNE
ARGKYCTVDDLSAIILVGGGTQIPLIKEWIAKKIPKIHIKSPPPIESIALGALAMTPGVKIKDILNKGLSIRLLNKREQT
HFWHPIFCKGQTWPTENPFKLILQASKINQKIFEIIIGETKKDREYDVIFENGLPKLSEIQSEEEIIRWDKKPLKILLKN
SSNIGEDNLILFFKINKKADLLVKCFDIQDEFLGEYNLGNIY

Sequences:

>Translated_522_residues
MEENLSGTLAIDLGNTNTVVAFQDEKDINTILVEIPNITSSPGVIPTAVWFEKPSEILKIGDSALKMINSSNSELFFHSN
FKRLIGNPVEKINQKNILSPTECGEKFFKFLWANIPQKYKIKRLVLTAPIDTYKGYREWLVNLCEEISVDEIALVDEPTA
ASLGINVPFGSKIMTLDIGGSTIDMNIVKIEGGEGKSDPIAELLKFKGNNVSSISKQKVRCAEIISKSGSKIGGKDIDQW
IVDFFIPDNKYPINLLKAEVIKCKLSSSAIKDDNKYPTKLLTEGHQEKEFFLSRETFEKIIIENNLLNHLNSLLKDLLNE
ARGKYCTVDDLSAIILVGGGTQIPLIKEWIAKKIPKIHIKSPPPIESIALGALAMTPGVKIKDILNKGLSIRLLNKREQT
HFWHPIFCKGQTWPTENPFKLILQASKINQKIFEIIIGETKKDREYDVIFENGLPKLSEIQSEEEIIRWDKKPLKILLKN
SSNIGEDNLILFFKINKKADLLVKCFDIQDEFLGEYNLGNIY
>Mature_522_residues
MEENLSGTLAIDLGNTNTVVAFQDEKDINTILVEIPNITSSPGVIPTAVWFEKPSEILKIGDSALKMINSSNSELFFHSN
FKRLIGNPVEKINQKNILSPTECGEKFFKFLWANIPQKYKIKRLVLTAPIDTYKGYREWLVNLCEEISVDEIALVDEPTA
ASLGINVPFGSKIMTLDIGGSTIDMNIVKIEGGEGKSDPIAELLKFKGNNVSSISKQKVRCAEIISKSGSKIGGKDIDQW
IVDFFIPDNKYPINLLKAEVIKCKLSSSAIKDDNKYPTKLLTEGHQEKEFFLSRETFEKIIIENNLLNHLNSLLKDLLNE
ARGKYCTVDDLSAIILVGGGTQIPLIKEWIAKKIPKIHIKSPPPIESIALGALAMTPGVKIKDILNKGLSIRLLNKREQT
HFWHPIFCKGQTWPTENPFKLILQASKINQKIFEIIIGETKKDREYDVIFENGLPKLSEIQSEEEIIRWDKKPLKILLKN
SSNIGEDNLILFFKINKKADLLVKCFDIQDEFLGEYNLGNIY

Specific function: Acts as a chaperone [H]

COG id: COG0443

COG function: function code O; Molecular chaperone

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the heat shock protein 70 family [H]

Homologues:

Organism=Escherichia coli, GI1786196, Length=486, Percent_Identity=22.4279835390947, Blast_Score=69, Evalue=6e-13,
Organism=Caenorhabditis elegans, GI17534771, Length=440, Percent_Identity=25, Blast_Score=71, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI17568549, Length=421, Percent_Identity=24.2280285035629, Blast_Score=67, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012725
- InterPro:   IPR018181
- InterPro:   IPR001023
- InterPro:   IPR013126 [H]

Pfam domain/function: PF00012 HSP70 [H]

EC number: NA

Molecular weight: Translated: 58802; Mature: 58802

Theoretical pI: Translated: 7.08; Mature: 7.08

Prosite motif: PS01036 HSP70_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
1.0 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEENLSGTLAIDLGNTNTVVAFQDEKDINTILVEIPNITSSPGVIPTAVWFEKPSEILKI
CCCCCCEEEEEEECCCEEEEEEECCCCCEEEEEEECCCCCCCCCCEEEHHHCCCHHHHHH
GDSALKMINSSNSELFFHSNFKRLIGNPVEKINQKNILSPTECGEKFFKFLWANIPQKYK
CHHHHHHHCCCCCEEEEECCHHHHHCCHHHHHCCCCCCCHHHHHHHHHHHHHHCCCCCEE
IKRLVLTAPIDTYKGYREWLVNLCEEISVDEIALVDEPTAASLGINVPFGSKIMTLDIGG
EEEEEEECCCHHHHHHHHHHHHHHHHCCCCCEEEECCCCCCEEEEECCCCCEEEEEEECC
STIDMNIVKIEGGEGKSDPIAELLKFKGNNVSSISKQKVRCAEIISKSGSKIGGKDIDQW
CEEEEEEEEEECCCCCCCHHHHHHHHCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCHHHH
IVDFFIPDNKYPINLLKAEVIKCKLSSSAIKDDNKYPTKLLTEGHQEKEFFLSRETFEKI
HHHEEECCCCCCHHHHHHHHHEEECCCCCCCCCCCCCHHHHHCCCCHHHHHHHHHHHHHH
IIENNLLNHLNSLLKDLLNEARGKYCTVDDLSAIILVGGGTQIPLIKEWIAKKIPKIHIK
HHHHHHHHHHHHHHHHHHHHHCCCEEEECCCCEEEEECCCCCCHHHHHHHHHCCCEEEEC
SPPPIESIALGALAMTPGVKIKDILNKGLSIRLLNKREQTHFWHPIFCKGQTWPTENPFK
CCCCHHHHHHHHHHCCCCCCHHHHHCCCCEEEEECCCCCCCCCCCEEECCCCCCCCCHHH
LILQASKINQKIFEIIIGETKKDREYDVIFENGLPKLSEIQSEEEIIRWDKKPLKILLKN
EEEEHHHHHHHHHHHHHCCCCCCCCEEEEEECCCCHHHHHCCHHHHHHCCCCCEEEEEEC
SSNIGEDNLILFFKINKKADLLVKCFDIQDEFLGEYNLGNIY
CCCCCCCCEEEEEEECCCCCEEEEEECCCHHHCCCCCCCCCC
>Mature Secondary Structure
MEENLSGTLAIDLGNTNTVVAFQDEKDINTILVEIPNITSSPGVIPTAVWFEKPSEILKI
CCCCCCEEEEEEECCCEEEEEEECCCCCEEEEEEECCCCCCCCCCEEEHHHCCCHHHHHH
GDSALKMINSSNSELFFHSNFKRLIGNPVEKINQKNILSPTECGEKFFKFLWANIPQKYK
CHHHHHHHCCCCCEEEEECCHHHHHCCHHHHHCCCCCCCHHHHHHHHHHHHHHCCCCCEE
IKRLVLTAPIDTYKGYREWLVNLCEEISVDEIALVDEPTAASLGINVPFGSKIMTLDIGG
EEEEEEECCCHHHHHHHHHHHHHHHHCCCCCEEEECCCCCCEEEEECCCCCEEEEEEECC
STIDMNIVKIEGGEGKSDPIAELLKFKGNNVSSISKQKVRCAEIISKSGSKIGGKDIDQW
CEEEEEEEEEECCCCCCCHHHHHHHHCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCHHHH
IVDFFIPDNKYPINLLKAEVIKCKLSSSAIKDDNKYPTKLLTEGHQEKEFFLSRETFEKI
HHHEEECCCCCCHHHHHHHHHEEECCCCCCCCCCCCCHHHHHCCCCHHHHHHHHHHHHHH
IIENNLLNHLNSLLKDLLNEARGKYCTVDDLSAIILVGGGTQIPLIKEWIAKKIPKIHIK
HHHHHHHHHHHHHHHHHHHHHCCCEEEECCCCEEEEECCCCCCHHHHHHHHHCCCEEEEC
SPPPIESIALGALAMTPGVKIKDILNKGLSIRLLNKREQTHFWHPIFCKGQTWPTENPFK
CCCCHHHHHHHHHHCCCCCCHHHHHCCCCEEEEECCCCCCCCCCCEEECCCCCCCCCHHH
LILQASKINQKIFEIIIGETKKDREYDVIFENGLPKLSEIQSEEEIIRWDKKPLKILLKN
EEEEHHHHHHHHHHHHHCCCCCCCCEEEEEECCCCHHHHHCCHHHHHHCCCCCEEEEEEC
SSNIGEDNLILFFKINKKADLLVKCFDIQDEFLGEYNLGNIY
CCCCCCCCEEEEEEECCCCCEEEEEECCCHHHCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA