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The map label for this gene is phrA [H]

Identifier: 78779842

GI number: 78779842

Start: 1368613

End: 1369767

Strand: Reverse

Name: phrA [H]

Synonym: PMT9312_1458

Alternate gene names: 78779842

Gene position: 1369767-1368613 (Counterclockwise)

Preceding gene: 78779844

Following gene: 78779841

Centisome position: 80.14

GC content: 27.36

Gene sequence:

>1155_bases
ATGTCATTTTTATTAGAAGCTCAAAATGTTTGGGACAATTTTGCAAAATACAAAATTAATGATTATTCAAAGTTAAGAAA
TTTCGATTTTGGGCCAAATAATGAAGGTTCAGTTTCAAAATTATCACCTTTCATTACGCATAGAATATTATCGGAATATG
ATCTGATTAATGATATTAAAAGTAAGTACAAAATCAAAAATTCAACTAAATTTGTTGAAGAAATATTTTGGAGAGTTTAC
TGGAAAGGGTGGATGGAAAATAGACCTAAAGTTTGGCAATATTTTACTTTAGAAAAAAATCTTGATTTTGATTATGAGCT
GTATGAAAATGCAATTAGTGGAAATACAGAATTAGATTTTTTTAACTCTTGGGTCCTTGAATTAAAGCAGTATAACTATT
TGCATAATCACACAAGAATGTGGTTTGCGAGTACTTGGATATTTAATTTAGGCCTTCCATGGCAATTAGGAGCAAAGTTT
TTCTTTAAATATCTCTTTGATGGTGATGCTGCATCTAATCTTCTTAGTTGGAGATGGGTCGCAGGATTACAAACTAAAGG
GAAGCGATATCTTTTTTCATCTTCAAACCTCAGAAAATTTTCAAATAATAGATTTAATGTAGAAAAAATAATTAACAAAC
AAATTTCTATTGAGGAATTGGATCAAATTCCATTAGAAGATGAGATTTATAAAAATAATATGGATCCTAAATCAGATAAT
TTGATTTTGTTTGAAAATGATCTGAACGTTGCAACTCTTAAAAATTTACTTCCAAGCTATAAAAAGGTATTCATTATTCT
TCTAAAGAATGAACAAAGACAAATTAAATTGTCTGAATCTGTTTTGAAATTTAAACATGCATTGGTCTCTGAATTTGCAG
AGCAATTTGATAATGTTGAACAGATTGAGCCTAATTCACTAGAACTCACCTTTGAAAATATTAATCAAATAGATATTATT
TATCCTGGGGTGGGAGAAAATTATGACTTTATAATTAAGTTCAAAAATTTACACAATAAGAAGATATTTAATCTCGTCAG
AGATGTAGATTTATTCGCATGGAAATTTGCTAAAAAAGGCTTCTTTAAATTTAAAGAAAACATTCCCGAAATAAATCAAA
GAATATTAGAAAATTATTCAAAAAATGATTTTTAA

Upstream 100 bases:

>100_bases
TACTGTAAATAATTGAATTCAGTATCGTGAGCTAAATTTAACCTCTAATTTTTCAAATTTTTTTCAATAAACAAAAAATA
TTTTTATAGTTATCAAAAAA

Downstream 100 bases:

>100_bases
CTGCAGTAAATTCTTAACTAGAAAAAAGAATTCTTTAGGTAACTAAGTATAAATACTTAATTAGGTATGACTTTTGCTGT
TTAATCCACGATGAAATCTG

Product: deoxyribodipyrimidine photo-lyase family protein

Products: NA

Alternate protein names: DNA photolyase; Photoreactivating enzyme [H]

Number of amino acids: Translated: 384; Mature: 383

Protein sequence:

>384_residues
MSFLLEAQNVWDNFAKYKINDYSKLRNFDFGPNNEGSVSKLSPFITHRILSEYDLINDIKSKYKIKNSTKFVEEIFWRVY
WKGWMENRPKVWQYFTLEKNLDFDYELYENAISGNTELDFFNSWVLELKQYNYLHNHTRMWFASTWIFNLGLPWQLGAKF
FFKYLFDGDAASNLLSWRWVAGLQTKGKRYLFSSSNLRKFSNNRFNVEKIINKQISIEELDQIPLEDEIYKNNMDPKSDN
LILFENDLNVATLKNLLPSYKKVFIILLKNEQRQIKLSESVLKFKHALVSEFAEQFDNVEQIEPNSLELTFENINQIDII
YPGVGENYDFIIKFKNLHNKKIFNLVRDVDLFAWKFAKKGFFKFKENIPEINQRILENYSKNDF

Sequences:

>Translated_384_residues
MSFLLEAQNVWDNFAKYKINDYSKLRNFDFGPNNEGSVSKLSPFITHRILSEYDLINDIKSKYKIKNSTKFVEEIFWRVY
WKGWMENRPKVWQYFTLEKNLDFDYELYENAISGNTELDFFNSWVLELKQYNYLHNHTRMWFASTWIFNLGLPWQLGAKF
FFKYLFDGDAASNLLSWRWVAGLQTKGKRYLFSSSNLRKFSNNRFNVEKIINKQISIEELDQIPLEDEIYKNNMDPKSDN
LILFENDLNVATLKNLLPSYKKVFIILLKNEQRQIKLSESVLKFKHALVSEFAEQFDNVEQIEPNSLELTFENINQIDII
YPGVGENYDFIIKFKNLHNKKIFNLVRDVDLFAWKFAKKGFFKFKENIPEINQRILENYSKNDF
>Mature_383_residues
SFLLEAQNVWDNFAKYKINDYSKLRNFDFGPNNEGSVSKLSPFITHRILSEYDLINDIKSKYKIKNSTKFVEEIFWRVYW
KGWMENRPKVWQYFTLEKNLDFDYELYENAISGNTELDFFNSWVLELKQYNYLHNHTRMWFASTWIFNLGLPWQLGAKFF
FKYLFDGDAASNLLSWRWVAGLQTKGKRYLFSSSNLRKFSNNRFNVEKIINKQISIEELDQIPLEDEIYKNNMDPKSDNL
ILFENDLNVATLKNLLPSYKKVFIILLKNEQRQIKLSESVLKFKHALVSEFAEQFDNVEQIEPNSLELTFENINQIDIIY
PGVGENYDFIIKFKNLHNKKIFNLVRDVDLFAWKFAKKGFFKFKENIPEINQRILENYSKNDF

Specific function: Involved in repair of UV radiation-induced DNA damage. Catalyzes the light-dependent monomerization (300-600 nm) of cyclobutyl pyrimidine dimers (in cis-syn configuration), which are formed between adjacent bases on the same DNA strand upon exposure to ul

COG id: COG0415

COG function: function code L; Deoxyribodipyrimidine photolyase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 DNA photolyase domain [H]

Homologues:

Organism=Saccharomyces cerevisiae, GI6324962, Length=174, Percent_Identity=28.1609195402299, Blast_Score=65, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002081
- InterPro:   IPR018394
- InterPro:   IPR006050
- InterPro:   IPR005101
- InterPro:   IPR014729 [H]

Pfam domain/function: PF00875 DNA_photolyase; PF03441 FAD_binding_7 [H]

EC number: =4.1.99.3 [H]

Molecular weight: Translated: 46054; Mature: 45923

Theoretical pI: Translated: 8.50; Mature: 8.50

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.0 %Met     (Translated Protein)
1.0 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
0.8 %Met     (Mature Protein)
0.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSFLLEAQNVWDNFAKYKINDYSKLRNFDFGPNNEGSVSKLSPFITHRILSEYDLINDIK
CCCEECHHHHHHHHHHCCCCCHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHH
SKYKIKNSTKFVEEIFWRVYWKGWMENRPKVWQYFTLEKNLDFDYELYENAISGNTELDF
HHHCCCCHHHHHHHHHHHHHHHHHHCCCCCEEEEEEEECCCCCCHHHHHHHHCCCCCHHH
FNSWVLELKQYNYLHNHTRMWFASTWIFNLGLPWQLGAKFFFKYLFDGDAASNLLSWRWV
HHHHHHHHHHHHHHHHCCEEEEEEEEEEECCCCHHHHHHHHHHHHHCCCHHHHHHHHHHH
AGLQTKGKRYLFSSSNLRKFSNNRFNVEKIINKQISIEELDQIPLEDEIYKNNMDPKSDN
HCCCCCCCEEEECCCCCHHHCCCCCCHHHHHCCCCCHHHHHCCCCCHHHHHCCCCCCCCC
LILFENDLNVATLKNLLPSYKKVFIILLKNEQRQIKLSESVLKFKHALVSEFAEQFDNVE
EEEEECCCCHHHHHHHCCCHHEEEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHCCHH
QIEPNSLELTFENINQIDIIYPGVGENYDFIIKFKNLHNKKIFNLVRDVDLFAWKFAKKG
HCCCCCEEEEECCCCEEEEEECCCCCCCEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHH
FFKFKENIPEINQRILENYSKNDF
HHHHHHCCHHHHHHHHHHCCCCCC
>Mature Secondary Structure 
SFLLEAQNVWDNFAKYKINDYSKLRNFDFGPNNEGSVSKLSPFITHRILSEYDLINDIK
CCEECHHHHHHHHHHCCCCCHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHH
SKYKIKNSTKFVEEIFWRVYWKGWMENRPKVWQYFTLEKNLDFDYELYENAISGNTELDF
HHHCCCCHHHHHHHHHHHHHHHHHHCCCCCEEEEEEEECCCCCCHHHHHHHHCCCCCHHH
FNSWVLELKQYNYLHNHTRMWFASTWIFNLGLPWQLGAKFFFKYLFDGDAASNLLSWRWV
HHHHHHHHHHHHHHHHCCEEEEEEEEEEECCCCHHHHHHHHHHHHHCCCHHHHHHHHHHH
AGLQTKGKRYLFSSSNLRKFSNNRFNVEKIINKQISIEELDQIPLEDEIYKNNMDPKSDN
HCCCCCCCEEEECCCCCHHHCCCCCCHHHHHCCCCCHHHHHCCCCCHHHHHCCCCCCCCC
LILFENDLNVATLKNLLPSYKKVFIILLKNEQRQIKLSESVLKFKHALVSEFAEQFDNVE
EEEEECCCCHHHHHHHCCCHHEEEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHCCHH
QIEPNSLELTFENINQIDIIYPGVGENYDFIIKFKNLHNKKIFNLVRDVDLFAWKFAKKG
HCCCCCEEEEECCCCEEEEEECCCCCCCEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHH
FFKFKENIPEINQRILENYSKNDF
HHHHHHCCHHHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 10952301 [H]