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The map label for this gene is 78779730

Identifier: 78779730

GI number: 78779730

Start: 1262379

End: 1263248

Strand: Direct

Name: 78779730

Synonym: PMT9312_1346

Alternate gene names: NA

Gene position: 1262379-1263248 (Clockwise)

Preceding gene: 78779729

Following gene: 78779731

Centisome position: 73.86

GC content: 31.95

Gene sequence:

>870_bases
ATGAATATTGTTAATTTCAATCAACTTGGTTTTGATAAATATATTTACTTGATAGCTGAAATAGGAATTAACCATAATGG
TTCAATTGATTTAGCTAAAAAGTTGATAGATCAAGCTGTAGATTGTGGATGTGATGCAGTAAAGTTCCAAAAGAGAGATA
TTAACACAGTTTATTCGAAAGAGATTTTAGATCAAGCCAGAGAAAGCCCATGGGGAAATACTCAAAGAGAACAAAAAGAG
GGTCTTGAATTTTCTTTAACACAATATGAAGAGCTAGATAAATATTGCAAAGGGAAGAATATTGATTGGTTTGCCTCTTC
TTGGGACAAAAAAAGTCAATTAGAAATGAGAAGGTTTAAATTTAAATTCAATAAAATAGCCTCTGCTATGGCTACAAACT
TAGATTTTGTTGAATTTGTAGCATCTGAAGGTACTCCTACTTTTGCATCAACTGGGATGACAGAAATTGAAGATATTGAA
AAAATAGTGGAAATTTTTAAGAGGCATTCATGTGAATTGATGCTTATGCATACTGTAAGCACATACCCCTCCTTAGAATC
TGATTTAAATTTAAAATGTATCAACATGCTTAAGAATAAATTTAAGCTCCCTGTTGGATATAGTGGTCACGAAGTTTCAG
TTTCTCCATCTGTAATAGCAGCAACATTAGGAGCATGCGCTATAGAGAGACACATAACACTAGATAGGTCAATGTATGGT
AGTGATCAATCAGCATCATTACAAGAAGAAGGCTTTAGACAATTAGTCTCTATTTGTAGAAAAATACCTATTCTTCTTGG
AGACGGAGAAAAGAAGATAATAGAAGCAGAAAAAACAATTGCCAATAAATTAAGATATTGGAAAAAATAA

Upstream 100 bases:

>100_bases
ATTAATGATTTGTTTTTACATTATTAAAACTATTTAGAAGATTTACTTTGATAAGTGGGAGATTAAAGTTAAAATACATT
ATCGTTAAATAATAATTTCG

Downstream 100 bases:

>100_bases
TGAAAACTTACGTTTTTGATATTGATGGAACTATTTGTACAAATACATATGGTGAATATAAAAAAGCTGAACCTTTTTTG
GAAAATATTTTAAAAGTAAA

Product: N-acetylneuraminate synthase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 289; Mature: 289

Protein sequence:

>289_residues
MNIVNFNQLGFDKYIYLIAEIGINHNGSIDLAKKLIDQAVDCGCDAVKFQKRDINTVYSKEILDQARESPWGNTQREQKE
GLEFSLTQYEELDKYCKGKNIDWFASSWDKKSQLEMRRFKFKFNKIASAMATNLDFVEFVASEGTPTFASTGMTEIEDIE
KIVEIFKRHSCELMLMHTVSTYPSLESDLNLKCINMLKNKFKLPVGYSGHEVSVSPSVIAATLGACAIERHITLDRSMYG
SDQSASLQEEGFRQLVSICRKIPILLGDGEKKIIEAEKTIANKLRYWKK

Sequences:

>Translated_289_residues
MNIVNFNQLGFDKYIYLIAEIGINHNGSIDLAKKLIDQAVDCGCDAVKFQKRDINTVYSKEILDQARESPWGNTQREQKE
GLEFSLTQYEELDKYCKGKNIDWFASSWDKKSQLEMRRFKFKFNKIASAMATNLDFVEFVASEGTPTFASTGMTEIEDIE
KIVEIFKRHSCELMLMHTVSTYPSLESDLNLKCINMLKNKFKLPVGYSGHEVSVSPSVIAATLGACAIERHITLDRSMYG
SDQSASLQEEGFRQLVSICRKIPILLGDGEKKIIEAEKTIANKLRYWKK
>Mature_289_residues
MNIVNFNQLGFDKYIYLIAEIGINHNGSIDLAKKLIDQAVDCGCDAVKFQKRDINTVYSKEILDQARESPWGNTQREQKE
GLEFSLTQYEELDKYCKGKNIDWFASSWDKKSQLEMRRFKFKFNKIASAMATNLDFVEFVASEGTPTFASTGMTEIEDIE
KIVEIFKRHSCELMLMHTVSTYPSLESDLNLKCINMLKNKFKLPVGYSGHEVSVSPSVIAATLGACAIERHITLDRSMYG
SDQSASLQEEGFRQLVSICRKIPILLGDGEKKIIEAEKTIANKLRYWKK

Specific function: Unknown

COG id: COG2089

COG function: function code M; Sialic acid synthase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: To B.subtilis spsE [H]

Homologues:

Organism=Homo sapiens, GI12056473, Length=279, Percent_Identity=35.1254480286738, Blast_Score=176, Evalue=2e-44,
Organism=Drosophila melanogaster, GI21357081, Length=247, Percent_Identity=39.6761133603239, Blast_Score=177, Evalue=6e-45,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006190
- InterPro:   IPR013785
- InterPro:   IPR013132
- InterPro:   IPR013974 [H]

Pfam domain/function: PF03102 NeuB; PF08666 SAF [H]

EC number: NA

Molecular weight: Translated: 32929; Mature: 32929

Theoretical pI: Translated: 7.00; Mature: 7.00

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.4 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
5.2 %Cys+Met (Translated Protein)
2.4 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
5.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNIVNFNQLGFDKYIYLIAEIGINHNGSIDLAKKLIDQAVDCGCDAVKFQKRDINTVYSK
CCCCCCCHHCHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHH
EILDQARESPWGNTQREQKEGLEFSLTQYEELDKYCKGKNIDWFASSWDKKSQLEMRRFK
HHHHHHHCCCCCCCHHHHHCCCCEEHHHHHHHHHHHCCCCCCHHHCCCCCHHHHHHHHHH
FKFNKIASAMATNLDFVEFVASEGTPTFASTGMTEIEDIEKIVEIFKRHSCELMLMHTVS
HHHHHHHHHHHCCCHHHHHHHCCCCCCHHHCCCHHHHHHHHHHHHHHHCCCCEEEEEHHH
TYPSLESDLNLKCINMLKNKFKLPVGYSGHEVSVSPSVIAATLGACAIERHITLDRSMYG
CCCCCCCCCCHHHHHHHHHHHCCCCCCCCCEEECCHHHHHHHHHHHHHHHHHHHHHHHCC
SDQSASLQEEGFRQLVSICRKIPILLGDGEKKIIEAEKTIANKLRYWKK
CCCCCCHHHHHHHHHHHHHHHCCEEECCCCHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MNIVNFNQLGFDKYIYLIAEIGINHNGSIDLAKKLIDQAVDCGCDAVKFQKRDINTVYSK
CCCCCCCHHCHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHH
EILDQARESPWGNTQREQKEGLEFSLTQYEELDKYCKGKNIDWFASSWDKKSQLEMRRFK
HHHHHHHCCCCCCCHHHHHCCCCEEHHHHHHHHHHHCCCCCCHHHCCCCCHHHHHHHHHH
FKFNKIASAMATNLDFVEFVASEGTPTFASTGMTEIEDIEKIVEIFKRHSCELMLMHTVS
HHHHHHHHHHHCCCHHHHHHHCCCCCCHHHCCCHHHHHHHHHHHHHHHCCCCEEEEEHHH
TYPSLESDLNLKCINMLKNKFKLPVGYSGHEVSVSPSVIAATLGACAIERHITLDRSMYG
CCCCCCCCCCHHHHHHHHHHHCCCCCCCCCEEECCHHHHHHHHHHHHHHHHHHHHHHHCC
SDQSASLQEEGFRQLVSICRKIPILLGDGEKKIIEAEKTIANKLRYWKK
CCCCCCHHHHHHHHHHHHHHHCCEEECCCCHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]