Click here to switch to the map view.

The map label for this gene is 78779724

Identifier: 78779724

GI number: 78779724

Start: 1255290

End: 1256855

Strand: Direct

Name: 78779724

Synonym: PMT9312_1340

Alternate gene names: NA

Gene position: 1255290-1256855 (Clockwise)

Preceding gene: 78779723

Following gene: 78779725

Centisome position: 73.44

GC content: 29.89

Gene sequence:

>1566_bases
ATGATATCCAAAAGGATAGATTTCAATAATGAAATTAATCATAAAATTAGGATCATATTTGAAATAGCAAATAACCATCA
AGGCAGTGTGGATCACTTTAAAAATATACTTGATGATATATTTTCTGCCAGCAAAACATTTGCCGATAAGTTTGAGTTTT
TAATTAAATTTCAATTTAGAGATTTACCAACTTTTATAGATGAAAGCATAGACCCCTCTCAAAATAAACATATTTCTAGA
TTTAAAGAAACTGCTCTTTTAGATGAACAATGGCTTCAAATTTTAAATATGGTAAGAGATAAAGGTTTTAAAACAATTGT
TACACCATTTGATGAGGCTTCAGTTAATAAAGCTGAAAGATTTGGGATCGAAGAATATAAAATTGCTAGTTGCTCTTGCA
CCGAATGGAGTTTGTTGAGAGAAGTGGCAAACCAGAATAAACCTGTCACAATTTCTACTGGTGGAAGAAATCTAAAAGAA
GTGGATGATATCTATTCATATTTTGCTCATAGAATACCTTATAAATTTACTATTATGCATTGTTGCGGAATCTATCCAGC
ACCAATAAAAGATTTAAACTTAAATACAATTAATATATTTAAGGAAAGATATCCTTTAGCAAAGATTGGATACTCAGGTC
ATGAAGATCCTGATAATCATAGTATTTCCTCCTTGGCAATAGCTCTTGGAGCTGTTTCTATTGAGAGGCATATAGGTAAA
GAAGACACTGAAAAAGATATTAATATTAATACTTACAGTGTTAGCAGCTCTTCTATTTATAAATGGCTAAAAGTACTTGA
TGAAACTTTGACCTCATTAGGCAAAGCTAAGGACTATTCATATAAAAATCAAGTTGAATATAAATCTTTAAAAACTCTCC
AAAGGGGTGTATTTTTGAAAAATGAAGTTAAAATTGGCGATAAGATTAATCTTAGTGATTGTAGTTTTAAATTCCCTATA
CAAGAAAATCAAATTTCAGCTTCTGAGATTGCATCAATTGATAATTGTTTCATAGCTAATCAAAATCTAATATCAGGAGC
AAGACTTACTTATGATAAAACGCAAATTCAAATATCCAAATCAATAAGTCTGAAGGAATATGTTCATAAAATAAGAGGTA
TCATTAATCAATATGGTGAATACGTTCCAGATGATGTTGAGATAGAGGTATCTCATCATTATGGAATTGAAAAATTGAAT
AAATATGGTTGTTGCCTTATAAATATAATTAACCGGAGCTACTGTAAAAAGTTAATTATCATGACTGAAGGTCAAAATCA
TCCAACTCAATTTCATGATGTAAAAGAGGAAACATTTCGAGTCCTGCATGGTGAACTAGAGCTTATTCTTGATGGTCAAA
AGAAAATTATCAAATGTGGAGAAGAAGCTTTAGTAAGATCTGGAGTAAAGCATTCTTTTAGAGCTATTACTGATTGTATT
ATTGAAGAACTCTCTACTACCAGTATTGCGGATGATTCAATTTATGAAGACACTAAAATTAATGATTTGCCAAGAGGTAA
AAGAAAAACTTTAGTTAATCTTCACTTTGATCATTTTGACGAATGA

Upstream 100 bases:

>100_bases
CATATACAAAGAAACGTAACTATTGTTATTTGCACTAAATTACATACTATTAACAAAAATTAGTTTATGTTAGAATATCG
ATATTTGAAAATTAAGGTTA

Downstream 100 bases:

>100_bases
GATGTCAAAAGTTCTCGGATTTATACCCTGCAGATCAGGTTCAAAAAGAATAAAAAATAAAAATCTTCTTACATTTAATT
CGAAGTCTCTCATACAAAAT

Product: N-acetylneuraminate synthase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 521; Mature: 521

Protein sequence:

>521_residues
MISKRIDFNNEINHKIRIIFEIANNHQGSVDHFKNILDDIFSASKTFADKFEFLIKFQFRDLPTFIDESIDPSQNKHISR
FKETALLDEQWLQILNMVRDKGFKTIVTPFDEASVNKAERFGIEEYKIASCSCTEWSLLREVANQNKPVTISTGGRNLKE
VDDIYSYFAHRIPYKFTIMHCCGIYPAPIKDLNLNTINIFKERYPLAKIGYSGHEDPDNHSISSLAIALGAVSIERHIGK
EDTEKDININTYSVSSSSIYKWLKVLDETLTSLGKAKDYSYKNQVEYKSLKTLQRGVFLKNEVKIGDKINLSDCSFKFPI
QENQISASEIASIDNCFIANQNLISGARLTYDKTQIQISKSISLKEYVHKIRGIINQYGEYVPDDVEIEVSHHYGIEKLN
KYGCCLINIINRSYCKKLIIMTEGQNHPTQFHDVKEETFRVLHGELELILDGQKKIIKCGEEALVRSGVKHSFRAITDCI
IEELSTTSIADDSIYEDTKINDLPRGKRKTLVNLHFDHFDE

Sequences:

>Translated_521_residues
MISKRIDFNNEINHKIRIIFEIANNHQGSVDHFKNILDDIFSASKTFADKFEFLIKFQFRDLPTFIDESIDPSQNKHISR
FKETALLDEQWLQILNMVRDKGFKTIVTPFDEASVNKAERFGIEEYKIASCSCTEWSLLREVANQNKPVTISTGGRNLKE
VDDIYSYFAHRIPYKFTIMHCCGIYPAPIKDLNLNTINIFKERYPLAKIGYSGHEDPDNHSISSLAIALGAVSIERHIGK
EDTEKDININTYSVSSSSIYKWLKVLDETLTSLGKAKDYSYKNQVEYKSLKTLQRGVFLKNEVKIGDKINLSDCSFKFPI
QENQISASEIASIDNCFIANQNLISGARLTYDKTQIQISKSISLKEYVHKIRGIINQYGEYVPDDVEIEVSHHYGIEKLN
KYGCCLINIINRSYCKKLIIMTEGQNHPTQFHDVKEETFRVLHGELELILDGQKKIIKCGEEALVRSGVKHSFRAITDCI
IEELSTTSIADDSIYEDTKINDLPRGKRKTLVNLHFDHFDE
>Mature_521_residues
MISKRIDFNNEINHKIRIIFEIANNHQGSVDHFKNILDDIFSASKTFADKFEFLIKFQFRDLPTFIDESIDPSQNKHISR
FKETALLDEQWLQILNMVRDKGFKTIVTPFDEASVNKAERFGIEEYKIASCSCTEWSLLREVANQNKPVTISTGGRNLKE
VDDIYSYFAHRIPYKFTIMHCCGIYPAPIKDLNLNTINIFKERYPLAKIGYSGHEDPDNHSISSLAIALGAVSIERHIGK
EDTEKDININTYSVSSSSIYKWLKVLDETLTSLGKAKDYSYKNQVEYKSLKTLQRGVFLKNEVKIGDKINLSDCSFKFPI
QENQISASEIASIDNCFIANQNLISGARLTYDKTQIQISKSISLKEYVHKIRGIINQYGEYVPDDVEIEVSHHYGIEKLN
KYGCCLINIINRSYCKKLIIMTEGQNHPTQFHDVKEETFRVLHGELELILDGQKKIIKCGEEALVRSGVKHSFRAITDCI
IEELSTTSIADDSIYEDTKINDLPRGKRKTLVNLHFDHFDE

Specific function: Unknown

COG id: COG2089

COG function: function code M; Sialic acid synthase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: To B.subtilis spsE [H]

Homologues:

Organism=Homo sapiens, GI12056473, Length=240, Percent_Identity=27.9166666666667, Blast_Score=84, Evalue=2e-16,
Organism=Drosophila melanogaster, GI21357081, Length=238, Percent_Identity=30.672268907563, Blast_Score=100, Evalue=3e-21,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006190
- InterPro:   IPR013785
- InterPro:   IPR013132
- InterPro:   IPR013974 [H]

Pfam domain/function: PF03102 NeuB; PF08666 SAF [H]

EC number: NA

Molecular weight: Translated: 59827; Mature: 59827

Theoretical pI: Translated: 6.69; Mature: 6.69

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.1 %Cys     (Translated Protein)
0.8 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
2.1 %Cys     (Mature Protein)
0.8 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MISKRIDFNNEINHKIRIIFEIANNHQGSVDHFKNILDDIFSASKTFADKFEFLIKFQFR
CCCCCCCCCCCCCCEEEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHEEHHC
DLPTFIDESIDPSQNKHISRFKETALLDEQWLQILNMVRDKGFKTIVTPFDEASVNKAER
CCCHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEECCCCCCCCCHHHH
FGIEEYKIASCSCTEWSLLREVANQNKPVTISTGGRNLKEVDDIYSYFAHRIPYKFTIMH
CCCCCEEEECCCCHHHHHHHHHHCCCCCEEEECCCCCHHHHHHHHHHHHHHCCCEEEEEH
CCGIYPAPIKDLNLNTINIFKERYPLAKIGYSGHEDPDNHSISSLAIALGAVSIERHIGK
HHCCCCCCCCCCCCCCEEHHHHCCCHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCC
EDTEKDININTYSVSSSSIYKWLKVLDETLTSLGKAKDYSYKNQVEYKSLKTLQRGVFLK
CCCCCCCCEEEEECCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHCCEEE
NEVKIGDKINLSDCSFKFPIQENQISASEIASIDNCFIANQNLISGARLTYDKTQIQISK
CCCCCCCEECCCCCCEECCCCCCCCCHHHHHCCCCEEEECCCCCCCCEEEECHHEEEEEC
SISLKEYVHKIRGIINQYGEYVPDDVEIEVSHHYGIEKLNKYGCCLINIINRSYCKKLII
CCCHHHHHHHHHHHHHHHHCCCCCCEEEEEECCCCHHHHCCCCCHHHHHHHHHHHCEEEE
MTEGQNHPTQFHDVKEETFRVLHGELELILDGQKKIIKCGEEALVRSGVKHSFRAITDCI
EECCCCCCCHHHHHHHHHHHHHHCCEEEEECCCHHHHHCCHHHHHHHHHHHHHHHHHHHH
IEELSTTSIADDSIYEDTKINDLPRGKRKTLVNLHFDHFDE
HHHHHCCCCCCCCCCCCCCCCCCCCCCCCEEEEEECCCCCC
>Mature Secondary Structure
MISKRIDFNNEINHKIRIIFEIANNHQGSVDHFKNILDDIFSASKTFADKFEFLIKFQFR
CCCCCCCCCCCCCCEEEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHEEHHC
DLPTFIDESIDPSQNKHISRFKETALLDEQWLQILNMVRDKGFKTIVTPFDEASVNKAER
CCCHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEECCCCCCCCCHHHH
FGIEEYKIASCSCTEWSLLREVANQNKPVTISTGGRNLKEVDDIYSYFAHRIPYKFTIMH
CCCCCEEEECCCCHHHHHHHHHHCCCCCEEEECCCCCHHHHHHHHHHHHHHCCCEEEEEH
CCGIYPAPIKDLNLNTINIFKERYPLAKIGYSGHEDPDNHSISSLAIALGAVSIERHIGK
HHCCCCCCCCCCCCCCEEHHHHCCCHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCC
EDTEKDININTYSVSSSSIYKWLKVLDETLTSLGKAKDYSYKNQVEYKSLKTLQRGVFLK
CCCCCCCCEEEEECCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHCCEEE
NEVKIGDKINLSDCSFKFPIQENQISASEIASIDNCFIANQNLISGARLTYDKTQIQISK
CCCCCCCEECCCCCCEECCCCCCCCCHHHHHCCCCEEEECCCCCCCCEEEECHHEEEEEC
SISLKEYVHKIRGIINQYGEYVPDDVEIEVSHHYGIEKLNKYGCCLINIINRSYCKKLII
CCCHHHHHHHHHHHHHHHHCCCCCCEEEEEECCCCHHHHCCCCCHHHHHHHHHHHCEEEE
MTEGQNHPTQFHDVKEETFRVLHGELELILDGQKKIIKCGEEALVRSGVKHSFRAITDCI
EECCCCCCCHHHHHHHHHHHHHHCCEEEEECCCHHHHHCCHHHHHHHHHHHHHHHHHHHH
IEELSTTSIADDSIYEDTKINDLPRGKRKTLVNLHFDHFDE
HHHHHCCCCCCCCCCCCCCCCCCCCCCCCEEEEEECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]