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The map label for this gene is sppA [C]

Identifier: 78779664

GI number: 78779664

Start: 1189798

End: 1190607

Strand: Direct

Name: sppA [C]

Synonym: PMT9312_1281

Alternate gene names: 78779664

Gene position: 1189798-1190607 (Clockwise)

Preceding gene: 78779660

Following gene: 78779665

Centisome position: 69.61

GC content: 33.46

Gene sequence:

>810_bases
ATGATTTGGCCTTTTAGACGAAAGTCAAAAAAAAGAATGGCTCGTATTTTAATTGATGAGCCTATTACAAGTTCAACAAG
AGTTTCTGTTCTTAAAGCTCTTAAACAAATTGAGGATAGAGAATTTCCTGCTTTAATCGTGAGAATTGATTCGCCAGGGG
GTACTGTAGGAGATAGCCAAGAAATATACTCTGCTATTAAAAGACTAAAAGATAAAGGTTGTAAAGTCATAGCTAGTTTT
GGGAATATATCTGCATCTGGAGGAGTTTACATTGGTGTTGCATCTGACAAAATAGTTGCAAATCCAGGCACGATTACAGG
ATCTATTGGAGTGATTATAAGGGGAAATAATTTATCTGAATTGTTAGATAAAGTTGGCATAAAATTTGAGACTGTTAAAA
GCGGCGTATTTAAAGATATACTTTCTCCAGATAAACCTTTAAGTGAGGAAGGTAGAAGACTGCTTCAAGGTCTAATAGAT
GAAAGCTACAAACAATTTACTGAAGCTGTTGCTGAAGGAAGAAATTTACCCGTTGAAGAAGTAAGAAAATTTTCCGATGG
AAGAATTTTTACTGGAACCCAAGCAAAAGAATTAGGACTTGTTGATGAAATTGGAGATGAATTTGTTGCCAGGGAAGTTG
CCGCAAAAATGGTCAATATTGATCCTAAATTGCAGCCTTTAACATTTGGGAAGAAAAAAAAGAAAATACTTGGATTAATT
CCTGGAAGTAAAGTTATTGAAAGAGTTATCAATTATATTTTCTTTGAGATTGATTCATCTAATAAAATACTTTGGTTATA
CAAGCCTTAA

Upstream 100 bases:

>100_bases
AAGTGCAAAAGGGAGTAACATTAAAAACCAATTTAGGATTGAATTCATTAAGTCTGCTGATAATCTTTTTAAAGTAGTTT
TATGTATTTACCTTAAAAGA

Downstream 100 bases:

>100_bases
ATTAATAGTTATAAAAAAATGAAAGATGATTATAAAATTACATTTATTCGAGGAGCTACAACAGCATCTGGTAATTCTAT
TGAAGAAATTGAAGATGCAG

Product: signal peptide peptidase A

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 269; Mature: 269

Protein sequence:

>269_residues
MIWPFRRKSKKRMARILIDEPITSSTRVSVLKALKQIEDREFPALIVRIDSPGGTVGDSQEIYSAIKRLKDKGCKVIASF
GNISASGGVYIGVASDKIVANPGTITGSIGVIIRGNNLSELLDKVGIKFETVKSGVFKDILSPDKPLSEEGRRLLQGLID
ESYKQFTEAVAEGRNLPVEEVRKFSDGRIFTGTQAKELGLVDEIGDEFVAREVAAKMVNIDPKLQPLTFGKKKKKILGLI
PGSKVIERVINYIFFEIDSSNKILWLYKP

Sequences:

>Translated_269_residues
MIWPFRRKSKKRMARILIDEPITSSTRVSVLKALKQIEDREFPALIVRIDSPGGTVGDSQEIYSAIKRLKDKGCKVIASF
GNISASGGVYIGVASDKIVANPGTITGSIGVIIRGNNLSELLDKVGIKFETVKSGVFKDILSPDKPLSEEGRRLLQGLID
ESYKQFTEAVAEGRNLPVEEVRKFSDGRIFTGTQAKELGLVDEIGDEFVAREVAAKMVNIDPKLQPLTFGKKKKKILGLI
PGSKVIERVINYIFFEIDSSNKILWLYKP
>Mature_269_residues
MIWPFRRKSKKRMARILIDEPITSSTRVSVLKALKQIEDREFPALIVRIDSPGGTVGDSQEIYSAIKRLKDKGCKVIASF
GNISASGGVYIGVASDKIVANPGTITGSIGVIIRGNNLSELLDKVGIKFETVKSGVFKDILSPDKPLSEEGRRLLQGLID
ESYKQFTEAVAEGRNLPVEEVRKFSDGRIFTGTQAKELGLVDEIGDEFVAREVAAKMVNIDPKLQPLTFGKKKKKILGLI
PGSKVIERVINYIFFEIDSSNKILWLYKP

Specific function: Digestion Of The Cleaved Signal Peptides. This Activity Is Necessary To Maintain Proper Secretion Of Mature Proteins Across The Membrane. [C]

COG id: COG0616

COG function: function code OU; Periplasmic serine proteases (ClpP class)

Gene ontology:

Cell location: Integral Membrane Protein. Inner Membrane [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase S49 family [H]

Homologues:

Organism=Escherichia coli, GI1788064, Length=182, Percent_Identity=34.0659340659341, Blast_Score=108, Evalue=5e-25,
Organism=Escherichia coli, GI1787527, Length=161, Percent_Identity=32.9192546583851, Blast_Score=90, Evalue=2e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004635
- InterPro:   IPR002142 [H]

Pfam domain/function: PF01343 Peptidase_S49 [H]

EC number: 3.4.21.-

Molecular weight: Translated: 29754; Mature: 29754

Theoretical pI: Translated: 10.17; Mature: 10.17

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
1.5 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
1.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIWPFRRKSKKRMARILIDEPITSSTRVSVLKALKQIEDREFPALIVRIDSPGGTVGDSQ
CCCCCHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHCCCCCCEEEEEECCCCCCCCCHH
EIYSAIKRLKDKGCKVIASFGNISASGGVYIGVASDKIVANPGTITGSIGVIIRGNNLSE
HHHHHHHHHHHCCCEEEEECCCCCCCCCEEEEEECCEEEECCCEEEECEEEEEECCCHHH
LLDKVGIKFETVKSGVFKDILSPDKPLSEEGRRLLQGLIDESYKQFTEAVAEGRNLPVEE
HHHHHCCCHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHH
VRKFSDGRIFTGTQAKELGLVDEIGDEFVAREVAAKMVNIDPKLQPLTFGKKKKKILGLI
HHHCCCCCEEECCCHHHCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHEEEEC
PGSKVIERVINYIFFEIDSSNKILWLYKP
CCHHHHHHHHHHEEEEECCCCCEEEEECC
>Mature Secondary Structure
MIWPFRRKSKKRMARILIDEPITSSTRVSVLKALKQIEDREFPALIVRIDSPGGTVGDSQ
CCCCCHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHCCCCCCEEEEEECCCCCCCCCHH
EIYSAIKRLKDKGCKVIASFGNISASGGVYIGVASDKIVANPGTITGSIGVIIRGNNLSE
HHHHHHHHHHHCCCEEEEECCCCCCCCCEEEEEECCEEEECCCEEEECEEEEEECCCHHH
LLDKVGIKFETVKSGVFKDILSPDKPLSEEGRRLLQGLIDESYKQFTEAVAEGRNLPVEE
HHHHHCCCHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHH
VRKFSDGRIFTGTQAKELGLVDEIGDEFVAREVAAKMVNIDPKLQPLTFGKKKKKILGLI
HHHCCCCCEEECCCHHHCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHEEEEC
PGSKVIERVINYIFFEIDSSNKILWLYKP
CCHHHHHHHHHHEEEEECCCCCEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Hydrolase; Acting on peptide bonds (Peptidases) [C]

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 8590279; 8905231 [H]