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The map label for this gene is ilvH

Identifier: 78779636

GI number: 78779636

Start: 1165912

End: 1166436

Strand: Direct

Name: ilvH

Synonym: PMT9312_1253

Alternate gene names: 78779636

Gene position: 1165912-1166436 (Clockwise)

Preceding gene: 78779635

Following gene: 78779639

Centisome position: 68.21

GC content: 36.0

Gene sequence:

>525_bases
ATGAAACATACATTATCAGTTCTTGTTGAAGACGAATCTGGAGCTTTGAGTAGAATCTCAGGTCTCTTTGCTAGAAGGGG
ATTCAACATAGATAGCCTTGCAGTAGGTCCCGCAGAATCCAAAGGAATTTCAAGGTTAACAATGGTTGTAGAAGGTGACG
ATGCAACTCTTCAACAAATGACTAAGCAACTTAATAAGTTATTTAATGTTCTGGGAGTTGTAGATTTTACTAATCTCGCA
GCTGTTGAGAGGGAATTGATGTTACTCAAAGTTTCATCTAAAGAAGATACCAGAAGTAATATCTTAGATATAGTTCAAAT
ATTCCGTGCAAAAGTTGTTGACGTTTCAGATATAGCCTTAACACTCGAAGTGGTTGGAGATCCTGGGAAGTTAGTTGCTT
TAGAGAAATTACTCGAACCTTACGGTATACTTGAAATCGCAAGAACTGGCAAGGTAGCTCTTAAACGATCTTCAGGAGTT
AATACAGAAATGTTGAAAATAAACAAATATTCTTTAGAAATTTAA

Upstream 100 bases:

>100_bases
AAATAGTATCCAATTCAGGGCATTGCATACATGATGAAGATCCTTCATTATTCAATAGAATCTCTTATGAATGGATTAGA
GAATTAAAACATTTTAAAAT

Downstream 100 bases:

>100_bases
TTAGATATCCGGACTTCCTTTATATAGTCATTTAACTTGATTTCTTTAAGTACATCTAATCCTTTAATAATCCTTCCAAA
AATTGAATATCTACCATCTA

Product: acetolactate synthase 3 regulatory subunit

Products: NA

Alternate protein names: Acetohydroxy-acid synthase small subunit; AHAS; ALS [H]

Number of amino acids: Translated: 174; Mature: 174

Protein sequence:

>174_residues
MKHTLSVLVEDESGALSRISGLFARRGFNIDSLAVGPAESKGISRLTMVVEGDDATLQQMTKQLNKLFNVLGVVDFTNLA
AVERELMLLKVSSKEDTRSNILDIVQIFRAKVVDVSDIALTLEVVGDPGKLVALEKLLEPYGILEIARTGKVALKRSSGV
NTEMLKINKYSLEI

Sequences:

>Translated_174_residues
MKHTLSVLVEDESGALSRISGLFARRGFNIDSLAVGPAESKGISRLTMVVEGDDATLQQMTKQLNKLFNVLGVVDFTNLA
AVERELMLLKVSSKEDTRSNILDIVQIFRAKVVDVSDIALTLEVVGDPGKLVALEKLLEPYGILEIARTGKVALKRSSGV
NTEMLKINKYSLEI
>Mature_174_residues
MKHTLSVLVEDESGALSRISGLFARRGFNIDSLAVGPAESKGISRLTMVVEGDDATLQQMTKQLNKLFNVLGVVDFTNLA
AVERELMLLKVSSKEDTRSNILDIVQIFRAKVVDVSDIALTLEVVGDPGKLVALEKLLEPYGILEIARTGKVALKRSSGV
NTEMLKINKYSLEI

Specific function: Valine and isoleucine biosynthesis; first step. [C]

COG id: COG0440

COG function: function code E; Acetolactate synthase, small (regulatory) subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ACT domain [H]

Homologues:

Organism=Escherichia coli, GI1786266, Length=157, Percent_Identity=43.312101910828, Blast_Score=125, Evalue=2e-30,
Organism=Saccharomyces cerevisiae, GI6319837, Length=205, Percent_Identity=31.219512195122, Blast_Score=114, Evalue=8e-27,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004789
- InterPro:   IPR019455
- InterPro:   IPR002912 [H]

Pfam domain/function: PF01842 ACT; PF10369 ALS_ss_C [H]

EC number: =2.2.1.6 [H]

Molecular weight: Translated: 19001; Mature: 19001

Theoretical pI: Translated: 6.00; Mature: 6.00

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKHTLSVLVEDESGALSRISGLFARRGFNIDSLAVGPAESKGISRLTMVVEGDDATLQQM
CCCEEEEEEECCCCHHHHHHHHHHHCCCCCCCEEECCCCCCCCEEEEEEEECCCHHHHHH
TKQLNKLFNVLGVVDFTNLAAVERELMLLKVSSKEDTRSNILDIVQIFRAKVVDVSDIAL
HHHHHHHHHHHHHHHHHHHHHHHHHEEEEEECCCCCHHHHHHHHHHHHHHHCCCHHHEEE
TLEVVGDPGKLVALEKLLEPYGILEIARTGKVALKRSSGVNTEMLKINKYSLEI
EEEEECCCCHHHHHHHHHCCCCCEEECCCCCEEEEECCCCCEEEEEEEEEEECC
>Mature Secondary Structure
MKHTLSVLVEDESGALSRISGLFARRGFNIDSLAVGPAESKGISRLTMVVEGDDATLQQM
CCCEEEEEEECCCCHHHHHHHHHHHCCCCCCCEEECCCCCCCCEEEEEEEECCCHHHHHH
TKQLNKLFNVLGVVDFTNLAAVERELMLLKVSSKEDTRSNILDIVQIFRAKVVDVSDIAL
HHHHHHHHHHHHHHHHHHHHHHHHHEEEEEECCCCCHHHHHHHHHHHHHHHCCCHHHEEE
TLEVVGDPGKLVALEKLLEPYGILEIARTGKVALKRSSGVNTEMLKINKYSLEI
EEEEECCCCHHHHHHHHHCCCCCEEECCCCCEEEEECCCCCEEEEEEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8590279; 8905231 [H]