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The map label for this gene is trxB [H]

Identifier: 78779630

GI number: 78779630

Start: 1161740

End: 1163116

Strand: Direct

Name: trxB [H]

Synonym: PMT9312_1247

Alternate gene names: 78779630

Gene position: 1161740-1163116 (Clockwise)

Preceding gene: 78779629

Following gene: 78779635

Centisome position: 67.97

GC content: 36.24

Gene sequence:

>1377_bases
ATGGAAAATAAAGAGAAAAATTCAAACTTAGAAAATGTTGTAATTATAGGCTCAGGACCTGCAGGTTATACAGCTGCGAT
ATATGCAGCAAGAGCAAATCTTCAACCTTTGCTTGTAACAGGATTTAATTCCGGTGGAATTCCTGGAGGTCAATTAATGA
CTACAACATTTGTTGAAAATTATCCAGGTTTCCCGGATGGAGTACTAGGTCCTGAACTGATGGACCTAATGAAGGCTCAA
GCTGAAAGATGGGGTACAAATTTATACGAAAGTGATGTCGTTTCGATTAATACTGATTTGCATCCCTTTGAATTAAAAAC
TTTAGATGGAACTATAAAAGCGAATTCAATTATTATTGCAACTGGGGCAAGTGCAAATAGATTGGGAGTCATAAATGAAG
ATAAATTCTGGAGTAAAGGAATAAGTGCTTGTGCAATTTGTGATGGAGCAACCCCACAATTTAGGGATGAAGAATTAGCT
GTCATAGGAGGCGGAGACTCTGCATGCGAAGAAGCAGCATACCTTACAAAATACGGTAGCAAGGTTCATTTGATTGTTAG
ATCAGAGAAATTAAGAGCTAGTGCAGCAATGGTTGACAGAGTAAAAGCTAATCCAAAAATACATATCCACTGGGAAACAA
AAGTAGAGAAAGCTAATGGTTCTGAATGGCTTGAGAAAATAGAAACTATCCATTCTCAAGAAGGTAAAGGGGAAATCAAT
ATTAAAGGTCTTTTTTACGCAATAGGACATACGCCTAATACAAAGTTCTTAGACAAAAAAATTGATTTAGATAATAAAGG
ATATATTGCTTGCAAACCAGGACGGCCAGAGACATCAGTCGAAGGCATTTTCGCAGCAGGTGATGTTGTTGATTCAGAAT
GGAGACAAGGAGTTACTGCTGCAGGAACAGGATGCATGGCTGCATTAGCGACTGAAAGGTGGCTAGCCGAGAAAAACTTA
GCAAAAACAATAATTAGAGAAACACCCGAACCAGATAAGAAACTTAATTCATCAGATTTTAATGAAGACGAAGTTAATGA
AGATACCTTCGATTCAAATTCTGAATGGCAAAAAGGGAGTTATGCATTGAGGAAACTTTATCACGAGAGTAAAAAACCTC
TCTTAGTGATTTTTAGTTCCCCAAGCTGCGGCCCATGTCATGTCTTAAAACCTCAATTAAAAAGGATAATTAAAGAATTA
AATGGTGCAGTGCTCGGCGTTGAAATAGATATTGATAAAGATCAAGATATTGCAAAACAAGCAGGCATTAACGGTACACC
AACAGTTCAACTTTTTAAAGACAAATTATTAAAAAAACAATGGCAAGGTGTTAAACAAAGAAGTGAATTTAAAGAAGCTA
TAAAAAATATTATATAA

Upstream 100 bases:

>100_bases
ACCAACAATTCAACGATTAAATAATTAATCGATCTTGTGAAGGCCGACCTTCATTATTTGGGATTATTTATTATTATTAG
AATTGAAATTAGCAAATAAT

Downstream 100 bases:

>100_bases
AGTAGATGTTTACTTATTATTCCTCTTAGGATTATTTTTATTAGTCATAGGTCTGGCACCCCCTGCATTCCTCTCTCTAT
AAGTTATCCTCCCTCTAGAA

Product: thioredoxin reductase

Products: NA

Alternate protein names: TRXR [H]

Number of amino acids: Translated: 458; Mature: 458

Protein sequence:

>458_residues
MENKEKNSNLENVVIIGSGPAGYTAAIYAARANLQPLLVTGFNSGGIPGGQLMTTTFVENYPGFPDGVLGPELMDLMKAQ
AERWGTNLYESDVVSINTDLHPFELKTLDGTIKANSIIIATGASANRLGVINEDKFWSKGISACAICDGATPQFRDEELA
VIGGGDSACEEAAYLTKYGSKVHLIVRSEKLRASAAMVDRVKANPKIHIHWETKVEKANGSEWLEKIETIHSQEGKGEIN
IKGLFYAIGHTPNTKFLDKKIDLDNKGYIACKPGRPETSVEGIFAAGDVVDSEWRQGVTAAGTGCMAALATERWLAEKNL
AKTIIRETPEPDKKLNSSDFNEDEVNEDTFDSNSEWQKGSYALRKLYHESKKPLLVIFSSPSCGPCHVLKPQLKRIIKEL
NGAVLGVEIDIDKDQDIAKQAGINGTPTVQLFKDKLLKKQWQGVKQRSEFKEAIKNII

Sequences:

>Translated_458_residues
MENKEKNSNLENVVIIGSGPAGYTAAIYAARANLQPLLVTGFNSGGIPGGQLMTTTFVENYPGFPDGVLGPELMDLMKAQ
AERWGTNLYESDVVSINTDLHPFELKTLDGTIKANSIIIATGASANRLGVINEDKFWSKGISACAICDGATPQFRDEELA
VIGGGDSACEEAAYLTKYGSKVHLIVRSEKLRASAAMVDRVKANPKIHIHWETKVEKANGSEWLEKIETIHSQEGKGEIN
IKGLFYAIGHTPNTKFLDKKIDLDNKGYIACKPGRPETSVEGIFAAGDVVDSEWRQGVTAAGTGCMAALATERWLAEKNL
AKTIIRETPEPDKKLNSSDFNEDEVNEDTFDSNSEWQKGSYALRKLYHESKKPLLVIFSSPSCGPCHVLKPQLKRIIKEL
NGAVLGVEIDIDKDQDIAKQAGINGTPTVQLFKDKLLKKQWQGVKQRSEFKEAIKNII
>Mature_458_residues
MENKEKNSNLENVVIIGSGPAGYTAAIYAARANLQPLLVTGFNSGGIPGGQLMTTTFVENYPGFPDGVLGPELMDLMKAQ
AERWGTNLYESDVVSINTDLHPFELKTLDGTIKANSIIIATGASANRLGVINEDKFWSKGISACAICDGATPQFRDEELA
VIGGGDSACEEAAYLTKYGSKVHLIVRSEKLRASAAMVDRVKANPKIHIHWETKVEKANGSEWLEKIETIHSQEGKGEIN
IKGLFYAIGHTPNTKFLDKKIDLDNKGYIACKPGRPETSVEGIFAAGDVVDSEWRQGVTAAGTGCMAALATERWLAEKNL
AKTIIRETPEPDKKLNSSDFNEDEVNEDTFDSNSEWQKGSYALRKLYHESKKPLLVIFSSPSCGPCHVLKPQLKRIIKEL
NGAVLGVEIDIDKDQDIAKQAGINGTPTVQLFKDKLLKKQWQGVKQRSEFKEAIKNII

Specific function: Unknown

COG id: COG0492

COG function: function code O; Thioredoxin reductase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family [H]

Homologues:

Organism=Escherichia coli, GI1787114, Length=313, Percent_Identity=43.1309904153355, Blast_Score=251, Evalue=5e-68,
Organism=Escherichia coli, GI87081763, Length=318, Percent_Identity=32.0754716981132, Blast_Score=124, Evalue=2e-29,
Organism=Saccharomyces cerevisiae, GI6320560, Length=310, Percent_Identity=51.2903225806452, Blast_Score=306, Evalue=3e-84,
Organism=Saccharomyces cerevisiae, GI6321898, Length=313, Percent_Identity=48.2428115015974, Blast_Score=295, Evalue=9e-81,

Paralogues:

None

Copy number: 808 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 2,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013027
- InterPro:   IPR008255
- InterPro:   IPR001327
- InterPro:   IPR000103
- InterPro:   IPR005982 [H]

Pfam domain/function: PF00070 Pyr_redox; PF07992 Pyr_redox_2 [H]

EC number: =1.8.1.9 [H]

Molecular weight: Translated: 50152; Mature: 50152

Theoretical pI: Translated: 6.14; Mature: 6.14

Prosite motif: PS00573 PYRIDINE_REDOX_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MENKEKNSNLENVVIIGSGPAGYTAAIYAARANLQPLLVTGFNSGGIPGGQLMTTTFVEN
CCCCCCCCCCCEEEEEECCCCCCEEEEEEECCCCCEEEEEECCCCCCCCCCEEEEEHHHC
YPGFPDGVLGPELMDLMKAQAERWGTNLYESDVVSINTDLHPFELKTLDGTIKANSIIIA
CCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCEEEEECCCCCEEEEECCCEEEECEEEEE
TGASANRLGVINEDKFWSKGISACAICDGATPQFRDEELAVIGGGDSACEEAAYLTKYGS
ECCCCCEEEECCCCHHHHHCCCEEEEECCCCCCCCCCCEEEEECCCHHHHHHHHHHHCCC
KVHLIVRSEKLRASAAMVDRVKANPKIHIHWETKVEKANGSEWLEKIETIHSQEGKGEIN
EEEEEEECCHHHHHHHHHHHHCCCCEEEEEEEEEEECCCCHHHHHHHHHHHCCCCCCEEE
IKGLFYAIGHTPNTKFLDKKIDLDNKGYIACKPGRPETSVEGIFAAGDVVDSEWRQGVTA
EEEEEEEECCCCCCCHHHCEECCCCCCEEEECCCCCCCCCCEEEEECCCCHHHHHCCCCC
AGTGCMAALATERWLAEKNLAKTIIRETPEPDKKLNSSDFNEDEVNEDTFDSNSEWQKGS
CCCHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHCCCCCCCCCCCCCCCCCCCCCCCCHHH
YALRKLYHESKKPLLVIFSSPSCGPCHVLKPQLKRIIKELNGAVLGVEIDIDKDQDIAKQ
HHHHHHHHHCCCCEEEEECCCCCCCCCCCCHHHHHHHHHHCCEEEEEEEECCCCHHHHHH
AGINGTPTVQLFKDKLLKKQWQGVKQRSEFKEAIKNII
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MENKEKNSNLENVVIIGSGPAGYTAAIYAARANLQPLLVTGFNSGGIPGGQLMTTTFVEN
CCCCCCCCCCCEEEEEECCCCCCEEEEEEECCCCCEEEEEECCCCCCCCCCEEEEEHHHC
YPGFPDGVLGPELMDLMKAQAERWGTNLYESDVVSINTDLHPFELKTLDGTIKANSIIIA
CCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCEEEEECCCCCEEEEECCCEEEECEEEEE
TGASANRLGVINEDKFWSKGISACAICDGATPQFRDEELAVIGGGDSACEEAAYLTKYGS
ECCCCCEEEECCCCHHHHHCCCEEEEECCCCCCCCCCCEEEEECCCHHHHHHHHHHHCCC
KVHLIVRSEKLRASAAMVDRVKANPKIHIHWETKVEKANGSEWLEKIETIHSQEGKGEIN
EEEEEEECCHHHHHHHHHHHHCCCCEEEEEEEEEEECCCCHHHHHHHHHHHCCCCCCEEE
IKGLFYAIGHTPNTKFLDKKIDLDNKGYIACKPGRPETSVEGIFAAGDVVDSEWRQGVTA
EEEEEEEECCCCCCCHHHCEECCCCCCEEEECCCCCCCCCCEEEEECCCCHHHHHCCCCC
AGTGCMAALATERWLAEKNLAKTIIRETPEPDKKLNSSDFNEDEVNEDTFDSNSEWQKGS
CCCHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHCCCCCCCCCCCCCCCCCCCCCCCCHHH
YALRKLYHESKKPLLVIFSSPSCGPCHVLKPQLKRIIKELNGAVLGVEIDIDKDQDIAKQ
HHHHHHHHHCCCCEEEEECCCCCCCCCCCCHHHHHHHHHHCCEEEEEEEECCCCHHHHHH
AGINGTPTVQLFKDKLLKKQWQGVKQRSEFKEAIKNII
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 10684935 [H]