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The map label for this gene is tldD [C]

Identifier: 78779341

GI number: 78779341

Start: 887723

End: 889147

Strand: Direct

Name: tldD [C]

Synonym: PMT9312_0957

Alternate gene names: 78779341

Gene position: 887723-889147 (Clockwise)

Preceding gene: 78779340

Following gene: 78779342

Centisome position: 51.94

GC content: 34.67

Gene sequence:

>1425_bases
ATGCTTTCTTCTCAAATTAAATCAAATGAAATCGAATTTGGTAGTTGCAATAAATATTTATTAGAAGAAATTATTTTCTA
TGGGATGGGACTTGGAGCTGATTTCGTAGAAATATTTATAGAAAATACCGACAACGCAAGTGTACTTGCTGAAGAGGATT
ACATTACAAGTGTAAGTCCATCATTTGGGAGAGGTGCTGGCATTAGAATCTTCAAAGACAAAAGGGACGGATTTGTTAGT
ACTAATGATTTATCTAAACATGGCTTGATGAGATCAGTATCCCAAGCTATTGAGATGTTAGATATAAATGACAAAAACAA
TAAAGAAGTATTTAACGGTCTAAATAAATATAGGGATTATAGTTTATCCAAGAAAACATGGATTGATGAAGTTCCATCAA
TTAATGAAATAAGTGAAAAACTATTATTCAGCACAAAGTTTCTAAAAAAAAATAACAAAATAATAACTAGAAAAGGAAGT
TACTCTAGAAATCTTCAAGAAGTAATAATAGCCTCCAGCGATGGAACCTATGCCTCCGATATTAGGTTGCATCAAACAGT
TGGACTTAACGTAATTGCTAGTGATGCCCAATATAGATCTAATGGAAGTAGAAGATTTGGATCGTCAGGATTGCCAAATG
AATTTAGATTATGGGATCATGAAAAGGCAGCAAATGATGTGTTTGAAAGTTCAATGAACATGTTGTATGCGGATTATGTT
GAGGCTGGACAAATGCCTGTTGTATTAGCTAATAAATTTGGTGGCGTTATATTTCATGAAGCCTGTGGACATTTGCTAGA
GACTACACAAATAGAGAGAGGAACAACACCCTTCGAGAATAAATTGAATGAAAAAATTGCTCATGAATCAGTCACAGCAA
TAGATGAAGGATTATCAGAAGGATCCTTTGGTTCATTATCAGTTGATGATGAAGGTATGGAACCAGAGAAATCAGTCCTT
ATAAAAGATGGTATTTTAAAAAAATTTATATCCGACAGGGCAGGTGAATTACGAACTGGCCATAAAAGAACAGGCAGTGG
AAGAAGGCAAAATTATTCATTTGCAGCAGCTTCAAGAATGAGAAATACTTACATAGCTAAAGGTGAGTACTCCAAAGAAG
ATTTAATAAATAGTATTAGTGATGGTCTTTACTGCAAATCAATGGGTGGAGGCAGTGTAGGTGCTACAGGACAATTTAAT
TTTGCAGTAGAAGAAGGATATTTAATTAAAAATGGAAAATTAACAAACCCTGTAAAGGGAGCAACTTTGATTGGTGAGGC
TAAAGAGGTTATGCCAAAAATATCAATGTGCGGAAATGACCTTGAATTAGCCCCTGGATTCTGTGGATCCATTAGTGGAA
GTGTCAACGTAACTGTTGGCCAACCTCATATTAAGGTTGATTCAATCACTGTTGGTGGAAGATAG

Upstream 100 bases:

>100_bases
TACCAACTATTAAGACTATACTTATTAAAACCTCTAGATAGCAAAGATTTCCAACCTTCGATTAGATAATCTTTTATATA
GAGCAAATTTATAAATTCAT

Downstream 100 bases:

>100_bases
GATATGAATTCAAGAGAACTTACAAATCAAATCTCCAAAGCTGCAGATTTCCTAAATCTTAAAAAATGGGATTATGGTGC
AAGTTTTTCTAATGATTATT

Product: putative modulator of DNA gyrase; TldD

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 474; Mature: 474

Protein sequence:

>474_residues
MLSSQIKSNEIEFGSCNKYLLEEIIFYGMGLGADFVEIFIENTDNASVLAEEDYITSVSPSFGRGAGIRIFKDKRDGFVS
TNDLSKHGLMRSVSQAIEMLDINDKNNKEVFNGLNKYRDYSLSKKTWIDEVPSINEISEKLLFSTKFLKKNNKIITRKGS
YSRNLQEVIIASSDGTYASDIRLHQTVGLNVIASDAQYRSNGSRRFGSSGLPNEFRLWDHEKAANDVFESSMNMLYADYV
EAGQMPVVLANKFGGVIFHEACGHLLETTQIERGTTPFENKLNEKIAHESVTAIDEGLSEGSFGSLSVDDEGMEPEKSVL
IKDGILKKFISDRAGELRTGHKRTGSGRRQNYSFAAASRMRNTYIAKGEYSKEDLINSISDGLYCKSMGGGSVGATGQFN
FAVEEGYLIKNGKLTNPVKGATLIGEAKEVMPKISMCGNDLELAPGFCGSISGSVNVTVGQPHIKVDSITVGGR

Sequences:

>Translated_474_residues
MLSSQIKSNEIEFGSCNKYLLEEIIFYGMGLGADFVEIFIENTDNASVLAEEDYITSVSPSFGRGAGIRIFKDKRDGFVS
TNDLSKHGLMRSVSQAIEMLDINDKNNKEVFNGLNKYRDYSLSKKTWIDEVPSINEISEKLLFSTKFLKKNNKIITRKGS
YSRNLQEVIIASSDGTYASDIRLHQTVGLNVIASDAQYRSNGSRRFGSSGLPNEFRLWDHEKAANDVFESSMNMLYADYV
EAGQMPVVLANKFGGVIFHEACGHLLETTQIERGTTPFENKLNEKIAHESVTAIDEGLSEGSFGSLSVDDEGMEPEKSVL
IKDGILKKFISDRAGELRTGHKRTGSGRRQNYSFAAASRMRNTYIAKGEYSKEDLINSISDGLYCKSMGGGSVGATGQFN
FAVEEGYLIKNGKLTNPVKGATLIGEAKEVMPKISMCGNDLELAPGFCGSISGSVNVTVGQPHIKVDSITVGGR
>Mature_474_residues
MLSSQIKSNEIEFGSCNKYLLEEIIFYGMGLGADFVEIFIENTDNASVLAEEDYITSVSPSFGRGAGIRIFKDKRDGFVS
TNDLSKHGLMRSVSQAIEMLDINDKNNKEVFNGLNKYRDYSLSKKTWIDEVPSINEISEKLLFSTKFLKKNNKIITRKGS
YSRNLQEVIIASSDGTYASDIRLHQTVGLNVIASDAQYRSNGSRRFGSSGLPNEFRLWDHEKAANDVFESSMNMLYADYV
EAGQMPVVLANKFGGVIFHEACGHLLETTQIERGTTPFENKLNEKIAHESVTAIDEGLSEGSFGSLSVDDEGMEPEKSVL
IKDGILKKFISDRAGELRTGHKRTGSGRRQNYSFAAASRMRNTYIAKGEYSKEDLINSISDGLYCKSMGGGSVGATGQFN
FAVEEGYLIKNGKLTNPVKGATLIGEAKEVMPKISMCGNDLELAPGFCGSISGSVNVTVGQPHIKVDSITVGGR

Specific function: Suppresses The Inhibitory Activity Of The Carbon Storage Regulator (Csra). [C]

COG id: COG0312

COG function: function code R; Predicted Zn-dependent proteases and their inactivated homologs

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase U62 family [H]

Homologues:

Organism=Escherichia coli, GI1789640, Length=458, Percent_Identity=31.2227074235808, Blast_Score=221, Evalue=1e-58,
Organism=Escherichia coli, GI1790682, Length=453, Percent_Identity=22.2958057395143, Blast_Score=72, Evalue=6e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002510 [H]

Pfam domain/function: PF01523 PmbA_TldD [H]

EC number: NA

Molecular weight: Translated: 51990; Mature: 51990

Theoretical pI: Translated: 5.94; Mature: 5.94

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLSSQIKSNEIEFGSCNKYLLEEIIFYGMGLGADFVEIFIENTDNASVLAEEDYITSVSP
CCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCCCEEEEEEECCCCCEEEECCCCEECCCC
SFGRGAGIRIFKDKRDGFVSTNDLSKHGLMRSVSQAIEMLDINDKNNKEVFNGLNKYRDY
CCCCCCCEEEEECCCCCCEECCCCHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHCC
SLSKKTWIDEVPSINEISEKLLFSTKFLKKNNKIITRKGSYSRNLQEVIIASSDGTYASD
CCCHHHHHHCCCCHHHHHHHHHHHHHHHHCCCEEEEECCCCCCCCEEEEEECCCCCCHHC
IRLHQTVGLNVIASDAQYRSNGSRRFGSSGLPNEFRLWDHEKAANDVFESSMNMLYADYV
EEEEEEECCEEEECCCHHHCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHH
EAGQMPVVLANKFGGVIFHEACGHLLETTQIERGTTPFENKLNEKIAHESVTAIDEGLSE
HCCCCCEEEECCCCCCHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHCCCC
GSFGSLSVDDEGMEPEKSVLIKDGILKKFISDRAGELRTGHKRTGSGRRQNYSFAAASRM
CCCCCEECCCCCCCHHHHEEHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCHHHHHHHH
RNTYIAKGEYSKEDLINSISDGLYCKSMGGGSVGATGQFNFAVEEGYLIKNGKLTNPVKG
HHHEEECCCCCHHHHHHHHHCCEEEECCCCCCCCCCCEEEEEEECCEEEECCCCCCCCCC
ATLIGEAKEVMPKISMCGNDLELAPGFCGSISGSVNVTVGQPHIKVDSITVGGR
CEECCCHHHHHHHHHHCCCCCCCCCCCCCCCCCCEEEEECCCEEEEEEEEECCC
>Mature Secondary Structure
MLSSQIKSNEIEFGSCNKYLLEEIIFYGMGLGADFVEIFIENTDNASVLAEEDYITSVSP
CCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCCCEEEEEEECCCCCEEEECCCCEECCCC
SFGRGAGIRIFKDKRDGFVSTNDLSKHGLMRSVSQAIEMLDINDKNNKEVFNGLNKYRDY
CCCCCCCEEEEECCCCCCEECCCCHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHCC
SLSKKTWIDEVPSINEISEKLLFSTKFLKKNNKIITRKGSYSRNLQEVIIASSDGTYASD
CCCHHHHHHCCCCHHHHHHHHHHHHHHHHCCCEEEEECCCCCCCCEEEEEECCCCCCHHC
IRLHQTVGLNVIASDAQYRSNGSRRFGSSGLPNEFRLWDHEKAANDVFESSMNMLYADYV
EEEEEEECCEEEECCCHHHCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHH
EAGQMPVVLANKFGGVIFHEACGHLLETTQIERGTTPFENKLNEKIAHESVTAIDEGLSE
HCCCCCEEEECCCCCCHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHCCCC
GSFGSLSVDDEGMEPEKSVLIKDGILKKFISDRAGELRTGHKRTGSGRRQNYSFAAASRM
CCCCCEECCCCCCCHHHHEEHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCHHHHHHHH
RNTYIAKGEYSKEDLINSISDGLYCKSMGGGSVGATGQFNFAVEEGYLIKNGKLTNPVKG
HHHEEECCCCCHHHHHHHHHCCEEEECCCCCCCCCCCEEEEEEECCEEEECCCCCCCCCC
ATLIGEAKEVMPKISMCGNDLELAPGFCGSISGSVNVTVGQPHIKVDSITVGGR
CEECCCHHHHHHHHHHCCCCCCCCCCCCCCCCCCEEEEECCCEEEEEEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8905231 [H]