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The map label for this gene is lspA [H]

Identifier: 78779269

GI number: 78779269

Start: 818086

End: 818544

Strand: Reverse

Name: lspA [H]

Synonym: PMT9312_0885

Alternate gene names: 78779269

Gene position: 818544-818086 (Counterclockwise)

Preceding gene: 78779270

Following gene: 78779268

Centisome position: 47.89

GC content: 17.86

Gene sequence:

>459_bases
ATGATTTATAAAATACAACCAAAATTATATTTTTTATCTTTAAGTATTTTTATTATTCTACTAGATCAATATACGAAATA
TTTAATATTTTACAATTATAAAATATTGATAAATAAAGATTTTATTTTATTTAGATTAGACTTTGTAAAAAATTACGGAG
CAGCTTTTAATATATTTAGTGGCAGTAGAATATTTTTATCTTTCATAAGCATTATTTTTTCAATATTACTTATTTATTTA
ATATTAAGGAAAAATAATTTAAACTCATTTGATCTTTATTCTTATAGCTTTATTCTAGGTGGGACTTTTGGTAATGGAAT
GGATAGAATATTAAAAGGTTTTGTAATTGATTTTATAGATTTAAATTTTATAAATTTCCCGTTATTTAATATTGCTGATA
TATCTATTAATATAGGTTTTATTTTCTTAATTTATAGCATTTTTAAAAACAAAGGATAA

Upstream 100 bases:

>100_bases
TAGGGAAATACTCTGTAGGTAAAATTGGATTTCATTTTTTAATGCTTTTCCCACTATTATTACTTATTGAACCTATAAAA
TGGTTAAAACATAGCAAATA

Downstream 100 bases:

>100_bases
TATGAATTACTTTAAATTAAAGTACATAAAATATTTTATCTTTATATTATTTCTATATATTTTATTTTCGATATTAACAA
GAATAGTAAATATTTATACG

Product: lipoprotein signal peptidase

Products: NA

Alternate protein names: Prolipoprotein signal peptidase; Signal peptidase II; SPase II [H]

Number of amino acids: Translated: 152; Mature: 152

Protein sequence:

>152_residues
MIYKIQPKLYFLSLSIFIILLDQYTKYLIFYNYKILINKDFILFRLDFVKNYGAAFNIFSGSRIFLSFISIIFSILLIYL
ILRKNNLNSFDLYSYSFILGGTFGNGMDRILKGFVIDFIDLNFINFPLFNIADISINIGFIFLIYSIFKNKG

Sequences:

>Translated_152_residues
MIYKIQPKLYFLSLSIFIILLDQYTKYLIFYNYKILINKDFILFRLDFVKNYGAAFNIFSGSRIFLSFISIIFSILLIYL
ILRKNNLNSFDLYSYSFILGGTFGNGMDRILKGFVIDFIDLNFINFPLFNIADISINIGFIFLIYSIFKNKG
>Mature_152_residues
MIYKIQPKLYFLSLSIFIILLDQYTKYLIFYNYKILINKDFILFRLDFVKNYGAAFNIFSGSRIFLSFISIIFSILLIYL
ILRKNNLNSFDLYSYSFILGGTFGNGMDRILKGFVIDFIDLNFINFPLFNIADISINIGFIFLIYSIFKNKG

Specific function: This protein specifically catalyzes the removal of signal peptides from prolipoproteins [H]

COG id: COG0597

COG function: function code MU; Lipoprotein signal peptidase

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase A8 family [H]

Homologues:

Organism=Escherichia coli, GI1786210, Length=147, Percent_Identity=31.9727891156463, Blast_Score=74, Evalue=5e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001872 [H]

Pfam domain/function: PF01252 Peptidase_A8 [H]

EC number: =3.4.23.36 [H]

Molecular weight: Translated: 17905; Mature: 17905

Theoretical pI: Translated: 9.86; Mature: 9.86

Prosite motif: PS00989 CLAT_ADAPTOR_S

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
1.3 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
1.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIYKIQPKLYFLSLSIFIILLDQYTKYLIFYNYKILINKDFILFRLDFVKNYGAAFNIFS
CEEEECCHHHHHHHHHHHHHHHHHHEEEEEEEEEEEEECCEEEEEEEHHHCCCCEEEECC
GSRIFLSFISIIFSILLIYLILRKNNLNSFDLYSYSFILGGTFGNGMDRILKGFVIDFID
CCHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEEEEEECCCCCCHHHHHHHHHHHHHC
LNFINFPLFNIADISINIGFIFLIYSIFKNKG
CCEECCCCEEEEEEEEHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MIYKIQPKLYFLSLSIFIILLDQYTKYLIFYNYKILINKDFILFRLDFVKNYGAAFNIFS
CEEEECCHHHHHHHHHHHHHHHHHHEEEEEEEEEEEEECCEEEEEEEHHHCCCCEEEECC
GSRIFLSFISIIFSILLIYLILRKNNLNSFDLYSYSFILGGTFGNGMDRILKGFVIDFID
CCHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEEEEEECCCCCCHHHHHHHHHHHHHC
LNFINFPLFNIADISINIGFIFLIYSIFKNKG
CCEECCCCEEEEEEEEHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 12240834 [H]