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The map label for this gene is ubiE [H]

Identifier: 78779263

GI number: 78779263

Start: 810557

End: 811612

Strand: Reverse

Name: ubiE [H]

Synonym: PMT9312_0879

Alternate gene names: 78779263

Gene position: 811612-810557 (Counterclockwise)

Preceding gene: 78779264

Following gene: 78779262

Centisome position: 47.48

GC content: 29.73

Gene sequence:

>1056_bases
ATGGCTAGGGAATCTATCTCAAAAATTGCATATAAAACGCTCCAACAGAGTAAAAGTATAGCTGGATTTGCCCATAAGCA
AATCAGTTCAAGGTTAATGAATTTTATTCTTCCCGATTCAAAGCTTGATAATTTTGATATAGATAAGGATCTTCTATTAC
AAATCCAAAAATCAATGGATAGCTTAAGAGAGGAAGATTGGAATGACGCTGAAAATAATATTTATCCAAAAAAATTATTG
TTTGATGAACCATGGTTAAGATATTTAACTCAATATCCTAAAATTTGGCTAGATATGCCTAATACATGGGATAGACGCAG
AAAACAAAATTTTGATGATCTTCCTAAATCTGTTGAAAAAGATAATTATCCACAGTATTACTTGAGGAATTTTCATCATC
AAACAGATGGTTATTTATCTGATTTTTCAGCTAGTATTTACGACTTACAAGTAGAGATACTTTTTAATGGAAGTGCTGAC
TCAATGAGGAGGAGAATAATTAAACCAATAAAAGAAGGTCTTGTAAATTTTAGTAATAGAAAGAAAAGTTCTATAAAAAT
ACTTGATGTGGCTACAGGTTCTGGAAGGACATTAAAACAATTAAGGGTAGCATTCCCTAAAGAAAAAATTACAGGAATAG
ATCTATCTGATTCATACCTAAAAGAGGCAAGCAGATATATTTCAGATTTAGATGGGGATTTAATTGAATTAATAAAAGGT
AATGCTGAAGAATTACCATTTGAAAATAATAGTTTTCAATGCATTTCCTGTGTTTATTTATTTCATGAATTACCAAGAGC
AATTAGAGCTAAAGTATTAAATGAATTTTTCAGAGTTCTTGAACCTGGAGGAACATTAGTATTAGCTGATTCGATTCAAA
TAAGCGATTCTCCTGACTTTACATCCATAATGGAAAACTTTTATAAATCTTTTCATGAGCCTTTTTATTGTGATTACATA
AAAGAGGATATAAATTCTAAAATTGAAGAAGTAGGGTTTAAAAATGTGAATTCAAATTCCTTTTTCATGACTAAGGTATG
GTCTGCTGTAAAGTAA

Upstream 100 bases:

>100_bases
TAAAAAATCTTTTCTATAAAATAAGTCAATTTGAGAAATATCACAAAATATTCTCAAATTGATTTTTTTTTTGTTGGAAT
ATATATATATATATTTAAAA

Downstream 100 bases:

>100_bases
ATTAAAACTTTTATGACATATTGGGACAAAGATACTATTAAGCTTGTACAAAGTCTTAATTGTAAGTTAAAAATTGATCA
TTCAAAATGGCATAAAGATA

Product: SAM (and some other nucleotide) binding motif:Generic methyl-transferase

Products: S-Adenosyl-L-Homocysteine; @OCTA02.txt*2- Polyprenyl-3-Methyl-6-Methoxy-1,4-Benzoquinol!; Menaquinol. [C]

Alternate protein names: NA

Number of amino acids: Translated: 351; Mature: 350

Protein sequence:

>351_residues
MARESISKIAYKTLQQSKSIAGFAHKQISSRLMNFILPDSKLDNFDIDKDLLLQIQKSMDSLREEDWNDAENNIYPKKLL
FDEPWLRYLTQYPKIWLDMPNTWDRRRKQNFDDLPKSVEKDNYPQYYLRNFHHQTDGYLSDFSASIYDLQVEILFNGSAD
SMRRRIIKPIKEGLVNFSNRKKSSIKILDVATGSGRTLKQLRVAFPKEKITGIDLSDSYLKEASRYISDLDGDLIELIKG
NAEELPFENNSFQCISCVYLFHELPRAIRAKVLNEFFRVLEPGGTLVLADSIQISDSPDFTSIMENFYKSFHEPFYCDYI
KEDINSKIEEVGFKNVNSNSFFMTKVWSAVK

Sequences:

>Translated_351_residues
MARESISKIAYKTLQQSKSIAGFAHKQISSRLMNFILPDSKLDNFDIDKDLLLQIQKSMDSLREEDWNDAENNIYPKKLL
FDEPWLRYLTQYPKIWLDMPNTWDRRRKQNFDDLPKSVEKDNYPQYYLRNFHHQTDGYLSDFSASIYDLQVEILFNGSAD
SMRRRIIKPIKEGLVNFSNRKKSSIKILDVATGSGRTLKQLRVAFPKEKITGIDLSDSYLKEASRYISDLDGDLIELIKG
NAEELPFENNSFQCISCVYLFHELPRAIRAKVLNEFFRVLEPGGTLVLADSIQISDSPDFTSIMENFYKSFHEPFYCDYI
KEDINSKIEEVGFKNVNSNSFFMTKVWSAVK
>Mature_350_residues
ARESISKIAYKTLQQSKSIAGFAHKQISSRLMNFILPDSKLDNFDIDKDLLLQIQKSMDSLREEDWNDAENNIYPKKLLF
DEPWLRYLTQYPKIWLDMPNTWDRRRKQNFDDLPKSVEKDNYPQYYLRNFHHQTDGYLSDFSASIYDLQVEILFNGSADS
MRRRIIKPIKEGLVNFSNRKKSSIKILDVATGSGRTLKQLRVAFPKEKITGIDLSDSYLKEASRYISDLDGDLIELIKGN
AEELPFENNSFQCISCVYLFHELPRAIRAKVLNEFFRVLEPGGTLVLADSIQISDSPDFTSIMENFYKSFHEPFYCDYIK
EDINSKIEEVGFKNVNSNSFFMTKVWSAVK

Specific function: Methyltransferase required for the conversion of dimethylmenaquinone (DMKH2) to menaquinone (MKH2) [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the methyltransferase superfamily. UbiE family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014122
- InterPro:   IPR004033 [H]

Pfam domain/function: PF01209 Ubie_methyltran [H]

EC number: 2.1.1.- [C]

Molecular weight: Translated: 40945; Mature: 40814

Theoretical pI: Translated: 6.39; Mature: 6.39

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MARESISKIAYKTLQQSKSIAGFAHKQISSRLMNFILPDSKLDNFDIDKDLLLQIQKSMD
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHH
SLREEDWNDAENNIYPKKLLFDEPWLRYLTQYPKIWLDMPNTWDRRRKQNFDDLPKSVEK
HHHHCCCCCCCCCCCCHHHHCCCHHHHHHHHCCEEEEECCCHHHHHHHCCHHHHHHHHCC
DNYPQYYLRNFHHQTDGYLSDFSASIYDLQVEILFNGSADSMRRRIIKPIKEGLVNFSNR
CCCHHHHHHHHCCCCCCHHHHHCCCEEEEEEEEEECCCHHHHHHHHHHHHHHHHHCCCCC
KKSSIKILDVATGSGRTLKQLRVAFPKEKITGIDLSDSYLKEASRYISDLDGDLIELIKG
CCCCEEEEEECCCCCHHHHHHHHHCCHHHCCCCCCCHHHHHHHHHHHHHCCHHHHHHHCC
NAEELPFENNSFQCISCVYLFHELPRAIRAKVLNEFFRVLEPGGTLVLADSIQISDSPDF
CHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEECCEEECCCCCH
TSIMENFYKSFHEPFYCDYIKEDINSKIEEVGFKNVNSNSFFMTKVWSAVK
HHHHHHHHHHHCCCEEHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHCC
>Mature Secondary Structure 
ARESISKIAYKTLQQSKSIAGFAHKQISSRLMNFILPDSKLDNFDIDKDLLLQIQKSMD
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHH
SLREEDWNDAENNIYPKKLLFDEPWLRYLTQYPKIWLDMPNTWDRRRKQNFDDLPKSVEK
HHHHCCCCCCCCCCCCHHHHCCCHHHHHHHHCCEEEEECCCHHHHHHHCCHHHHHHHHCC
DNYPQYYLRNFHHQTDGYLSDFSASIYDLQVEILFNGSADSMRRRIIKPIKEGLVNFSNR
CCCHHHHHHHHCCCCCCHHHHHCCCEEEEEEEEEECCCHHHHHHHHHHHHHHHHHCCCCC
KKSSIKILDVATGSGRTLKQLRVAFPKEKITGIDLSDSYLKEASRYISDLDGDLIELIKG
CCCCEEEEEECCCCCHHHHHHHHHCCHHHCCCCCCCHHHHHHHHHHHHHCCHHHHHHHCC
NAEELPFENNSFQCISCVYLFHELPRAIRAKVLNEFFRVLEPGGTLVLADSIQISDSPDF
CHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEECCEEECCCCCH
TSIMENFYKSFHEPFYCDYIKEDINSKIEEVGFKNVNSNSFFMTKVWSAVK
HHHHHHHHHHHCCCEEHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: S-Adenosyl-L-Methionine; 2-Polyprenyl-6- Methoxy-1,4-Benzoquinol; Demethylmenaquinol [C]

Specific reaction: S-Adenosyl-L-Methionine + @OCTA02.txt*2-Polyprenyl-6- Methoxy-1,4-Benzoquinol! = S-Adenosyl-L-Homocysteine + 2- Polyprenyl-3-Methyl-6-Methoxy -1,4-Benzoquinol S-Adenosyl-L-Methionine + Demethylmenaquinol = S-Adenosyl-L-Homocysteine + Menaquinol. [C]

General reaction: Transferring one-carbon groups; Methyltransferases [C]

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11679669 [H]