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The map label for this gene is ctaB [H]

Identifier: 78778832

GI number: 78778832

Start: 422992

End: 423993

Strand: Direct

Name: ctaB [H]

Synonym: PMT9312_0447

Alternate gene names: 78778832

Gene position: 422992-423993 (Clockwise)

Preceding gene: 78778831

Following gene: 78778833

Centisome position: 24.75

GC content: 37.23

Gene sequence:

>1002_bases
ATGAATAGTAGTAACTTGGAAAACTTTAACTATAAATCTTCAATTAGGGATGAAGTTGTTCCTTCAAGAAAAAGATTAAC
TTTGCCACCTTGGCTTGAAGTAGCAAAACCAAGATTGATTCCACTTTTACTTGCAACAACTTTGGGCGGAATGGCTTTAA
CAGAGGAATGGCCTTTGTCATCACCAAAACTTATCTGTACTTTAGGTGGAGGAGCTTTGGCAGCAGCGGCAGCAGGAGCA
CTTAATTGCTTGTGGGAAATGGAATTAGACAAAAGGATGATAAGAACTAGCAAAAGAGCTTTGCCATCAGGTAAGTTATC
ATCTGAGACTGTATTTTTAGCTGCAGTATCATGTACTTTGGCAGCTTCGATGCTTTTAATAAGTGGTGTAAATTATTTAG
CTGCGGGACTTACACTTCTTGGTTTATGTAGCTACGTAATTTTATATACCGTGATTTTGAAGCCACGTACAACTAAAAAT
ATTGTTTTTGGAGGAGTGGCTGGTGCGATACCCCCTTTGGTCGGAGCATCTGCTGCTACAGGACATGTAGGACTTAGTGG
TTGGTGGTTGTTTGGTTTAGTAATGTTGTGGACTCCAGCTCATTTTTGGGCACTTGCAATTTTGTTAAAGGATGATTATG
CATCTGTTGGTATTCCTATGCTCCCTTCTGTTAAAGGATCTCTTTTTACTGCTAAAGCGATTTCTCGTTATGGATTGGCA
ACTGTTCTAATGAGTATTATGGGAGTTTTTGCTTTGCCTGAAGGCGGTCTTCTATACGGAATTATGTTATTGCCATTTAA
TGGAAGACTTTTGCAATTAATAAATAAATTAAAGAAATCACCTGATGATCTTTTAAGAGCAAAGTCCCTTTTTAGGTGGT
CAATTCTATATATGTTTGGTATTTGTCTCTTATTATTAATTTCTAGAACCCAACTATCAGTGGAATTTGAGCAGCAATCT
ATGCAAATATTTTTCTCTATAGGATCTCTCCTTAGTAATTAA

Upstream 100 bases:

>100_bases
CTTTATTTATTGCGATATTAACAACATTAATTTTTAGAAATCCTTTTGCCAAAAAAAACCTAAACCACTCACTAAATTCT
CAAATGGTTGGTATTAATTC

Downstream 100 bases:

>100_bases
ATTAGATGTAAAATGTTTTTAGAAAATAGTATGTTTGATGAATTATATAAAAGTTAAAGAGCTCTCAAAATCATATTCAG
ATATTGAGGCATTAAAAAAT

Product: protoheme IX farnesyltransferase

Products: NA

Alternate protein names: Heme B farnesyltransferase; Heme O synthase [H]

Number of amino acids: Translated: 333; Mature: 333

Protein sequence:

>333_residues
MNSSNLENFNYKSSIRDEVVPSRKRLTLPPWLEVAKPRLIPLLLATTLGGMALTEEWPLSSPKLICTLGGGALAAAAAGA
LNCLWEMELDKRMIRTSKRALPSGKLSSETVFLAAVSCTLAASMLLISGVNYLAAGLTLLGLCSYVILYTVILKPRTTKN
IVFGGVAGAIPPLVGASAATGHVGLSGWWLFGLVMLWTPAHFWALAILLKDDYASVGIPMLPSVKGSLFTAKAISRYGLA
TVLMSIMGVFALPEGGLLYGIMLLPFNGRLLQLINKLKKSPDDLLRAKSLFRWSILYMFGICLLLLISRTQLSVEFEQQS
MQIFFSIGSLLSN

Sequences:

>Translated_333_residues
MNSSNLENFNYKSSIRDEVVPSRKRLTLPPWLEVAKPRLIPLLLATTLGGMALTEEWPLSSPKLICTLGGGALAAAAAGA
LNCLWEMELDKRMIRTSKRALPSGKLSSETVFLAAVSCTLAASMLLISGVNYLAAGLTLLGLCSYVILYTVILKPRTTKN
IVFGGVAGAIPPLVGASAATGHVGLSGWWLFGLVMLWTPAHFWALAILLKDDYASVGIPMLPSVKGSLFTAKAISRYGLA
TVLMSIMGVFALPEGGLLYGIMLLPFNGRLLQLINKLKKSPDDLLRAKSLFRWSILYMFGICLLLLISRTQLSVEFEQQS
MQIFFSIGSLLSN
>Mature_333_residues
MNSSNLENFNYKSSIRDEVVPSRKRLTLPPWLEVAKPRLIPLLLATTLGGMALTEEWPLSSPKLICTLGGGALAAAAAGA
LNCLWEMELDKRMIRTSKRALPSGKLSSETVFLAAVSCTLAASMLLISGVNYLAAGLTLLGLCSYVILYTVILKPRTTKN
IVFGGVAGAIPPLVGASAATGHVGLSGWWLFGLVMLWTPAHFWALAILLKDDYASVGIPMLPSVKGSLFTAKAISRYGLA
TVLMSIMGVFALPEGGLLYGIMLLPFNGRLLQLINKLKKSPDDLLRAKSLFRWSILYMFGICLLLLISRTQLSVEFEQQS
MQIFFSIGSLLSN

Specific function: Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group [H]

COG id: COG0109

COG function: function code O; Polyprenyltransferase (cytochrome oxidase assembly factor)

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ubiA prenyltransferase family. Protoheme IX farnesyltransferase subfamily [H]

Homologues:

Organism=Homo sapiens, GI17921982, Length=189, Percent_Identity=34.3915343915344, Blast_Score=92, Evalue=5e-19,
Organism=Escherichia coli, GI1786631, Length=275, Percent_Identity=29.8181818181818, Blast_Score=110, Evalue=1e-25,
Organism=Caenorhabditis elegans, GI71998235, Length=264, Percent_Identity=29.9242424242424, Blast_Score=80, Evalue=1e-15,
Organism=Saccharomyces cerevisiae, GI6325085, Length=306, Percent_Identity=27.4509803921569, Blast_Score=90, Evalue=5e-19,
Organism=Drosophila melanogaster, GI19921064, Length=286, Percent_Identity=32.5174825174825, Blast_Score=110, Evalue=2e-24,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006369
- InterPro:   IPR000537 [H]

Pfam domain/function: PF01040 UbiA [H]

EC number: 2.5.1.-

Molecular weight: Translated: 35998; Mature: 35998

Theoretical pI: Translated: 10.04; Mature: 10.04

Prosite motif: PS00943 UBIA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
5.1 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
3.6 %Met     (Mature Protein)
5.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNSSNLENFNYKSSIRDEVVPSRKRLTLPPWLEVAKPRLIPLLLATTLGGMALTEEWPLS
CCCCCCCCCCCHHHHHHHHCCCCCCCCCCCHHHHCCCHHHHHHHHHHHCCCEECCCCCCC
SPKLICTLGGGALAAAAAGALNCLWEMELDKRMIRTSKRALPSGKLSSETVFLAAVSCTL
CCCEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHH
AASMLLISGVNYLAAGLTLLGLCSYVILYTVILKPRTTKNIVFGGVAGAIPPLVGASAAT
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEECCHHHHHCHHHCCCCCC
GHVGLSGWWLFGLVMLWTPAHFWALAILLKDDYASVGIPMLPSVKGSLFTAKAISRYGLA
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHCCCCCCCCCCCCHHHHHHHHHHHHH
TVLMSIMGVFALPEGGLLYGIMLLPFNGRLLQLINKLKKSPDDLLRAKSLFRWSILYMFG
HHHHHHHHHHCCCCCCCEEEEEEECCCCHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHH
ICLLLLISRTQLSVEFEQQSMQIFFSIGSLLSN
HHHHHHHHHHHHEEEEHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MNSSNLENFNYKSSIRDEVVPSRKRLTLPPWLEVAKPRLIPLLLATTLGGMALTEEWPLS
CCCCCCCCCCCHHHHHHHHCCCCCCCCCCCHHHHCCCHHHHHHHHHHHCCCEECCCCCCC
SPKLICTLGGGALAAAAAGALNCLWEMELDKRMIRTSKRALPSGKLSSETVFLAAVSCTL
CCCEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHH
AASMLLISGVNYLAAGLTLLGLCSYVILYTVILKPRTTKNIVFGGVAGAIPPLVGASAAT
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEECCHHHHHCHHHCCCCCC
GHVGLSGWWLFGLVMLWTPAHFWALAILLKDDYASVGIPMLPSVKGSLFTAKAISRYGLA
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHCCCCCCCCCCCCHHHHHHHHHHHHH
TVLMSIMGVFALPEGGLLYGIMLLPFNGRLLQLINKLKKSPDDLLRAKSLFRWSILYMFG
HHHHHHHHHHCCCCCCCEEEEEEECCCCHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHH
ICLLLLISRTQLSVEFEQQSMQIFFSIGSLLSN
HHHHHHHHHHHHEEEEHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA