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The map label for this gene is minD [H]

Identifier: 78778712

GI number: 78778712

Start: 310075

End: 310890

Strand: Reverse

Name: minD [H]

Synonym: PMT9312_0327

Alternate gene names: 78778712

Gene position: 310890-310075 (Counterclockwise)

Preceding gene: 78778713

Following gene: 78778711

Centisome position: 18.19

GC content: 36.76

Gene sequence:

>816_bases
GTGGCGGAAAATACTCGCACAATATTAATTTGTTCAGGGAAAGGTGGAGTTGGTAAAACCACTTTAACTGCAAACCTTGG
CATAGCACTTGCCAACAGTGGAGCAACTACTGCTGTATTAGATGCTGATTTTGGCTTAAGAAATTTAGATCTTCTTCTAG
GATTGGAAAATCGCATTATATATACAGCACAAGATGTTTTAGATAAAAATTGTCGTCTTGACCAAGCATTAGTCAGACAT
AAAAAAGAACCTAATCTGGCTCTTTTACCTGCAGGAGATCCTAGGATGTTGGATTGGATGAAGCCCGACGATATGAAAAA
AATTAGCGAGCTGCTTAGTGAAAAGTTTGATTTTGTTTTAGTAGATTGTCCTGCTGGAGTAGAAGATGGTTTTAAAAATG
CCCTTGCAGCTTGTAAAGAGGCTATTGTTGTTACCAACCCGGAATTATCTGCAGTACGTGATGCCGATAGAGTAATAGGT
ATTCTTAATACTTCTGATATTAAGCCTATCCAGCTTGTAATCAATAGAGTTCGCCCTAACATGATGGCAAGTCAAGAAAT
GCTATCCATAGAAGATGTTCAAGGGATCCTTTCACTACCTTTATTAGGTATTGTTTTAGAGGATGAGCAAGTAATAATTA
GTACAAATAGAGGAGAGCCACTAACACTTACAGATAGTAAATCCCCTGCAAAAAAATGTTATTTGAATGTTTCTCAAAGA
CTTACAGGAAAGGATGTCCCAATTATTGACCCCAAAAATGAAGGGAAAAGCCTCAAAGATAAATTCATGAGATTAATGCA
AACAAAGGTTTTTTAA

Upstream 100 bases:

>100_bases
AAATAAATTAATTCAAACTTGATAAATTTAAGAATTACTTAATCTTTATAATATTCAACTTTCTGAAAGTAGACTTATCA
TTTGTAAAATAATAAAATTC

Downstream 100 bases:

>100_bases
AAATGATGACTCTCAGAGATCTTATAAATAAGTTACTAGGTAGAGAAACTGCCAGTGCAAATACAGCTAGAGAAAGATTA
CAACTTGTACTAGCTCATGA

Product: putative septum site-determining protein MinD

Products: NA

Alternate protein names: Cell division inhibitor minD [H]

Number of amino acids: Translated: 271; Mature: 270

Protein sequence:

>271_residues
MAENTRTILICSGKGGVGKTTLTANLGIALANSGATTAVLDADFGLRNLDLLLGLENRIIYTAQDVLDKNCRLDQALVRH
KKEPNLALLPAGDPRMLDWMKPDDMKKISELLSEKFDFVLVDCPAGVEDGFKNALAACKEAIVVTNPELSAVRDADRVIG
ILNTSDIKPIQLVINRVRPNMMASQEMLSIEDVQGILSLPLLGIVLEDEQVIISTNRGEPLTLTDSKSPAKKCYLNVSQR
LTGKDVPIIDPKNEGKSLKDKFMRLMQTKVF

Sequences:

>Translated_271_residues
MAENTRTILICSGKGGVGKTTLTANLGIALANSGATTAVLDADFGLRNLDLLLGLENRIIYTAQDVLDKNCRLDQALVRH
KKEPNLALLPAGDPRMLDWMKPDDMKKISELLSEKFDFVLVDCPAGVEDGFKNALAACKEAIVVTNPELSAVRDADRVIG
ILNTSDIKPIQLVINRVRPNMMASQEMLSIEDVQGILSLPLLGIVLEDEQVIISTNRGEPLTLTDSKSPAKKCYLNVSQR
LTGKDVPIIDPKNEGKSLKDKFMRLMQTKVF
>Mature_270_residues
AENTRTILICSGKGGVGKTTLTANLGIALANSGATTAVLDADFGLRNLDLLLGLENRIIYTAQDVLDKNCRLDQALVRHK
KEPNLALLPAGDPRMLDWMKPDDMKKISELLSEKFDFVLVDCPAGVEDGFKNALAACKEAIVVTNPELSAVRDADRVIGI
LNTSDIKPIQLVINRVRPNMMASQEMLSIEDVQGILSLPLLGIVLEDEQVIISTNRGEPLTLTDSKSPAKKCYLNVSQRL
TGKDVPIIDPKNEGKSLKDKFMRLMQTKVF

Specific function: ATPase required for the correct placement of the division site. Cell division inhibitors minC and minD act in concert to form an inhibitor capable of blocking formation of the polar Z ring septums. Rapidly oscillates between the poles of the cell to desta

COG id: COG2894

COG function: function code D; Septum formation inhibitor-activating ATPase

Gene ontology:

Cell location: Cell membrane; Peripheral membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the parA family. MinD subfamily [H]

Homologues:

Organism=Homo sapiens, GI6912540, Length=261, Percent_Identity=23.7547892720307, Blast_Score=73, Evalue=3e-13,
Organism=Escherichia coli, GI1787423, Length=262, Percent_Identity=40.0763358778626, Blast_Score=189, Evalue=2e-49,
Organism=Saccharomyces cerevisiae, GI6322188, Length=179, Percent_Identity=27.9329608938547, Blast_Score=64, Evalue=2e-11,
Organism=Drosophila melanogaster, GI24667611, Length=201, Percent_Identity=27.363184079602, Blast_Score=68, Evalue=7e-12,

Paralogues:

None

Copy number: 300 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002586
- InterPro:   IPR010223 [H]

Pfam domain/function: PF01656 CbiA [H]

EC number: NA

Molecular weight: Translated: 29656; Mature: 29525

Theoretical pI: Translated: 5.50; Mature: 5.50

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
5.2 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
4.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAENTRTILICSGKGGVGKTTLTANLGIALANSGATTAVLDADFGLRNLDLLLGLENRII
CCCCCCEEEEECCCCCCCCEEEEEECCEEEECCCCEEEEEECCCCCCCEEEEEECCCCEE
YTAQDVLDKNCRLDQALVRHKKEPNLALLPAGDPRMLDWMKPDDMKKISELLSEKFDFVL
EEEHHHHCCCCCHHHHHHHCCCCCCEEEEECCCCCEECCCCCHHHHHHHHHHHCCCCEEE
VDCPAGVEDGFKNALAACKEAIVVTNPELSAVRDADRVIGILNTSDIKPIQLVINRVRPN
EECCCCHHHHHHHHHHHHHCEEEEECCCHHHHHCCCCEEEEECCCCCCHHHHHHHHHCCC
MMASQEMLSIEDVQGILSLPLLGIVLEDEQVIISTNRGEPLTLTDSKSPAKKCYLNVSQR
HHHHHHHHHHHHHHHHHHCCEEEEEECCCEEEEECCCCCEEEEECCCCCHHHHHHHHHHH
LTGKDVPIIDPKNEGKSLKDKFMRLMQTKVF
CCCCCCCEECCCCCCCHHHHHHHHHHHHHCC
>Mature Secondary Structure 
AENTRTILICSGKGGVGKTTLTANLGIALANSGATTAVLDADFGLRNLDLLLGLENRII
CCCCCEEEEECCCCCCCCEEEEEECCEEEECCCCEEEEEECCCCCCCEEEEEECCCCEE
YTAQDVLDKNCRLDQALVRHKKEPNLALLPAGDPRMLDWMKPDDMKKISELLSEKFDFVL
EEEHHHHCCCCCHHHHHHHCCCCCCEEEEECCCCCEECCCCCHHHHHHHHHHHCCCCEEE
VDCPAGVEDGFKNALAACKEAIVVTNPELSAVRDADRVIGILNTSDIKPIQLVINRVRPN
EECCCCHHHHHHHHHHHHHCEEEEECCCHHHHHCCCCEEEEECCCCCCHHHHHHHHHCCC
MMASQEMLSIEDVQGILSLPLLGIVLEDEQVIISTNRGEPLTLTDSKSPAKKCYLNVSQR
HHHHHHHHHHHHHHHHHHCCEEEEEECCCEEEEECCCCCEEEEECCCCCHHHHHHHHHHH
LTGKDVPIIDPKNEGKSLKDKFMRLMQTKVF
CCCCCCCEECCCCCCCHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 8590279; 8905231 [H]