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The map label for this gene is nrdR

Identifier: 78778704

GI number: 78778704

Start: 304868

End: 305347

Strand: Reverse

Name: nrdR

Synonym: PMT9312_0319

Alternate gene names: 78778704

Gene position: 305347-304868 (Counterclockwise)

Preceding gene: 78778705

Following gene: 78778703

Centisome position: 17.86

GC content: 30.83

Gene sequence:

>480_bases
ATGCAGTGTCCAACCTGTCAAAATACAGATAGCAGAGTTTTGGAATCAAGATCTGCTGATAGTGGGAAAAGTGTTCGAAG
AAGAAGAGAGTGCCTAAATTGCAGCTTTAGATTTACCACTTATGAAAGAGTTGAAACAATGCCAGTTTCAGTTATTAAAA
AAGATGGGAACAGTGAATTATTTGATAAACAAAAATTATTTACTGGTATATCAAGAGCCTGCGAAAAGACTACCTTCACC
AGTGAAGCAATTATTAATTTTGTAGATGGAATAGAATCACAAATTTTACAAGATTCTAATAAGGATATTAAATCTTCACA
AATTGGAGAATTAATACTTAAAAGTCTTAGGAAAGAAAACGAAGTTGCATATATAAGATATGCTTCAGTTTATAGAAAAT
TCAATGGAGTAAAAGATTTTATCTCTACTCTTGAATCCCTCAAAGGAGCTTCAAAAAATCAATTAGCTTCAATTTTATAA

Upstream 100 bases:

>100_bases
ACTTAGAAAAAAAAACCTCTTTAACAAGAGGTTTTTTTTTACTTTTCATAATTAAGATATTACTCTAATATGAGAATTAA
AGATTACCTTATTTCACTAA

Downstream 100 bases:

>100_bases
AATTTAGCATCTTAAAGTGTAGAATACATAACACAAATATTTTTGCTATTGGTTTGCAGGCTAATAGCACTCCTTTCTAA
CTACCTAAGGTAGTCTGCGA

Product: transcriptional regulator NrdR

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 159; Mature: 159

Protein sequence:

>159_residues
MQCPTCQNTDSRVLESRSADSGKSVRRRRECLNCSFRFTTYERVETMPVSVIKKDGNSELFDKQKLFTGISRACEKTTFT
SEAIINFVDGIESQILQDSNKDIKSSQIGELILKSLRKENEVAYIRYASVYRKFNGVKDFISTLESLKGASKNQLASIL

Sequences:

>Translated_159_residues
MQCPTCQNTDSRVLESRSADSGKSVRRRRECLNCSFRFTTYERVETMPVSVIKKDGNSELFDKQKLFTGISRACEKTTFT
SEAIINFVDGIESQILQDSNKDIKSSQIGELILKSLRKENEVAYIRYASVYRKFNGVKDFISTLESLKGASKNQLASIL
>Mature_159_residues
MQCPTCQNTDSRVLESRSADSGKSVRRRRECLNCSFRFTTYERVETMPVSVIKKDGNSELFDKQKLFTGISRACEKTTFT
SEAIINFVDGIESQILQDSNKDIKSSQIGELILKSLRKENEVAYIRYASVYRKFNGVKDFISTLESLKGASKNQLASIL

Specific function: Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes [H]

COG id: COG1327

COG function: function code K; Predicted transcriptional regulator, consists of a Zn-ribbon and ATP-cone domains

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ATP-cone domain [H]

Homologues:

Organism=Escherichia coli, GI1786615, Length=140, Percent_Identity=41.4285714285714, Blast_Score=120, Evalue=6e-29,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005144
- InterPro:   IPR003796 [H]

Pfam domain/function: PF03477 ATP-cone [H]

EC number: NA

Molecular weight: Translated: 18027; Mature: 18027

Theoretical pI: Translated: 9.26; Mature: 9.26

Prosite motif: PS51161 ATP_CONE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.1 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
3.1 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQCPTCQNTDSRVLESRSADSGKSVRRRRECLNCSFRFTTYERVETMPVSVIKKDGNSEL
CCCCCCCCCHHHHHHHCCCCCCHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHCCCCCHH
FDKQKLFTGISRACEKTTFTSEAIINFVDGIESQILQDSNKDIKSSQIGELILKSLRKEN
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHCCC
EVAYIRYASVYRKFNGVKDFISTLESLKGASKNQLASIL
CCHHHHHHHHHHHHCCHHHHHHHHHHHCCCCHHHHHHCC
>Mature Secondary Structure
MQCPTCQNTDSRVLESRSADSGKSVRRRRECLNCSFRFTTYERVETMPVSVIKKDGNSEL
CCCCCCCCCHHHHHHHCCCCCCHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHCCCCCHH
FDKQKLFTGISRACEKTTFTSEAIINFVDGIESQILQDSNKDIKSSQIGELILKSLRKEN
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHCCC
EVAYIRYASVYRKFNGVKDFISTLESLKGASKNQLASIL
CCHHHHHHHHHHHHCCHHHHHHHHHHHCCCCHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA