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The map label for this gene is anmK

Identifier: 78484696

GI number: 78484696

Start: 399440

End: 400504

Strand: Reverse

Name: anmK

Synonym: Tcr_0351

Alternate gene names: 78484696

Gene position: 400504-399440 (Counterclockwise)

Preceding gene: 78484697

Following gene: 78484685

Centisome position: 16.5

GC content: 46.38

Gene sequence:

>1065_bases
ATGTCCGGCACCAGTTTAGATGGCGTGGATGCGGCCCTAGTCAGCATTCAAAATGGTGAGCTCGAACTAAAAGCATTTCA
AACCTTTCCTTACACAGACAACTTAAAAAAACAGCTTCACCATCTCAACCAGACACCTCATGTTGACTTGAAAGCCCTCT
GCGACATGGAATACCAAGTGGCAAATGCTTTTTCAGAGGCCACACAGCAGCTCTTAGACAACTGTGATCATGTGGCCTCT
GACATCCGTGCGATTGGAAGTCACGGACAAACGATTTTTCATGCACCAGACATTCCAATGAGTTTGCAAATAGGTCATCC
AGCCTTTATCGCTAAAAATACCGGTATTACAACAGTTGCAGACTTCAGAATTGACGACATGGCCAATAACGGTCAAGGCG
CACCATTGGCGCCAGCCTTCCACCAAAAACTGTTTGGCAACACCGTTGGCACGGCCGTGGTGAACATTGGTGGCATCTCC
AACATTACGTTCCTTGACCAGCAAAAAACGCTTGGCTTTGATACCGGACCGGGCAATGGCTTAATGGATGAATACTGTGA
ACAGTTTTTTAACTGCTCGTACGATGCCGATGGAAAAATGGCTCAAACGGGCCAGGTAAACATGGCCTTATTATCCGACT
TAATGCAGGAACCTTATTTCAGGTTACCCGCCCCTAAAACCACCGGCAAAGATCTTTTTAATTCGGATTGGCTCAACCCT
TTTCTGGCAAAGTATTCAAATGTGTCCAAAAAAGACATTCTATCCACACTAAACCAACTGACGGTGGACACGATTATTCA
AGGGCTCAATACCCTTCCATCACAGCCTAAAAGACTGTTGATTTGTGGTGGCGGAGCCGAAAACAAAACATTGATCTCTC
GACTGCAAGCACAATTGAGTTATCCCGTAAAGACCACACAATCTGTTGGTGTCCCGCCTCACGCGATAGAAGCAATGATG
TGTGCTTGGCTGGCTGAACAACGCCTTAATAATACCCCGATTGCCTTACAACACATCACTGGGGCAACAAAAGACTCTGT
TCTAGGCGCCGTCTGGCATCCTTAA

Upstream 100 bases:

>100_bases
TATGCAGAATTGATGTCAGCACAACTGGATCGATTGAATCCACACACACAACTGGTGTCAAACTTTGAGTAACCCGCCAT
CGAAGCTGTACATCGGGCTA

Downstream 100 bases:

>100_bases
TATAGCCCAGGCCTGGGCGTTTTAACTTGACGACCAAATACAAACACAAACGTTAAAACAAAAAAACCGCTATTAAGCGG
TTTTTTTAAAGGTCTTAGCA

Product: anhydro-N-acetylmuramic acid kinase

Products: NA

Alternate protein names: AnhMurNAc kinase

Number of amino acids: Translated: 354; Mature: 353

Protein sequence:

>354_residues
MSGTSLDGVDAALVSIQNGELELKAFQTFPYTDNLKKQLHHLNQTPHVDLKALCDMEYQVANAFSEATQQLLDNCDHVAS
DIRAIGSHGQTIFHAPDIPMSLQIGHPAFIAKNTGITTVADFRIDDMANNGQGAPLAPAFHQKLFGNTVGTAVVNIGGIS
NITFLDQQKTLGFDTGPGNGLMDEYCEQFFNCSYDADGKMAQTGQVNMALLSDLMQEPYFRLPAPKTTGKDLFNSDWLNP
FLAKYSNVSKKDILSTLNQLTVDTIIQGLNTLPSQPKRLLICGGGAENKTLISRLQAQLSYPVKTTQSVGVPPHAIEAMM
CAWLAEQRLNNTPIALQHITGATKDSVLGAVWHP

Sequences:

>Translated_354_residues
MSGTSLDGVDAALVSIQNGELELKAFQTFPYTDNLKKQLHHLNQTPHVDLKALCDMEYQVANAFSEATQQLLDNCDHVAS
DIRAIGSHGQTIFHAPDIPMSLQIGHPAFIAKNTGITTVADFRIDDMANNGQGAPLAPAFHQKLFGNTVGTAVVNIGGIS
NITFLDQQKTLGFDTGPGNGLMDEYCEQFFNCSYDADGKMAQTGQVNMALLSDLMQEPYFRLPAPKTTGKDLFNSDWLNP
FLAKYSNVSKKDILSTLNQLTVDTIIQGLNTLPSQPKRLLICGGGAENKTLISRLQAQLSYPVKTTQSVGVPPHAIEAMM
CAWLAEQRLNNTPIALQHITGATKDSVLGAVWHP
>Mature_353_residues
SGTSLDGVDAALVSIQNGELELKAFQTFPYTDNLKKQLHHLNQTPHVDLKALCDMEYQVANAFSEATQQLLDNCDHVASD
IRAIGSHGQTIFHAPDIPMSLQIGHPAFIAKNTGITTVADFRIDDMANNGQGAPLAPAFHQKLFGNTVGTAVVNIGGISN
ITFLDQQKTLGFDTGPGNGLMDEYCEQFFNCSYDADGKMAQTGQVNMALLSDLMQEPYFRLPAPKTTGKDLFNSDWLNPF
LAKYSNVSKKDILSTLNQLTVDTIIQGLNTLPSQPKRLLICGGGAENKTLISRLQAQLSYPVKTTQSVGVPPHAIEAMMC
AWLAEQRLNNTPIALQHITGATKDSVLGAVWHP

Specific function: Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived

COG id: COG2377

COG function: function code O; Predicted molecular chaperone distantly related to HSP70-fold metalloproteases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the anhydro-N-acetylmuramic acid kinase family

Homologues:

Organism=Escherichia coli, GI1787928, Length=356, Percent_Identity=41.0112359550562, Blast_Score=239, Evalue=2e-64,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): ANMK_THICR (Q31IS6)

Other databases:

- EMBL:   CP000109
- RefSeq:   YP_390621.1
- ProteinModelPortal:   Q31IS6
- SMR:   Q31IS6
- STRING:   Q31IS6
- GeneID:   3762337
- GenomeReviews:   CP000109_GR
- KEGG:   tcx:Tcr_0351
- NMPDR:   fig|317025.3.peg.320
- eggNOG:   COG2377
- HOGENOM:   HBG324434
- PhylomeDB:   Q31IS6
- ProtClustDB:   PRK09585
- BioCyc:   TCRU317025:TCR_0351-MONOMER
- HAMAP:   MF_01270
- InterPro:   IPR005338

Pfam domain/function: PF03702 UPF0075

EC number: NA

Molecular weight: Translated: 38427; Mature: 38296

Theoretical pI: Translated: 5.72; Mature: 5.72

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSGTSLDGVDAALVSIQNGELELKAFQTFPYTDNLKKQLHHLNQTPHVDLKALCDMEYQV
CCCCCCCCCCEEEEEEECCCEEEEEEEECCCCHHHHHHHHHCCCCCCCCHHHHHCCHHHH
ANAFSEATQQLLDNCDHVASDIRAIGSHGQTIFHAPDIPMSLQIGHPAFIAKNTGITTVA
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCCCEEEEECCCEEEECCCCCEEEE
DFRIDDMANNGQGAPLAPAFHQKLFGNTVGTAVVNIGGISNITFLDQQKTLGFDTGPGNG
EEEECCCCCCCCCCCCCHHHHHHHHCCHHHHHHEECCCCCCEEEECCCCCCCCCCCCCCC
LMDEYCEQFFNCSYDADGKMAQTGQVNMALLSDLMQEPYFRLPAPKTTGKDLFNSDWLNP
HHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHCCCEECCCCCCCCCHHHCCCCCCH
FLAKYSNVSKKDILSTLNQLTVDTIIQGLNTLPSQPKRLLICGGGAENKTLISRLQAQLS
HHHHHCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEECCCCCHHHHHHHHHHHHC
YPVKTTQSVGVPPHAIEAMMCAWLAEQRLNNTPIALQHITGATKDSVLGAVWHP
CCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCHHHHCCCCCCC
>Mature Secondary Structure 
SGTSLDGVDAALVSIQNGELELKAFQTFPYTDNLKKQLHHLNQTPHVDLKALCDMEYQV
CCCCCCCCCEEEEEEECCCEEEEEEEECCCCHHHHHHHHHCCCCCCCCHHHHHCCHHHH
ANAFSEATQQLLDNCDHVASDIRAIGSHGQTIFHAPDIPMSLQIGHPAFIAKNTGITTVA
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCCCEEEEECCCEEEECCCCCEEEE
DFRIDDMANNGQGAPLAPAFHQKLFGNTVGTAVVNIGGISNITFLDQQKTLGFDTGPGNG
EEEECCCCCCCCCCCCCHHHHHHHHCCHHHHHHEECCCCCCEEEECCCCCCCCCCCCCCC
LMDEYCEQFFNCSYDADGKMAQTGQVNMALLSDLMQEPYFRLPAPKTTGKDLFNSDWLNP
HHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHCCCEECCCCCCCCCHHHCCCCCCH
FLAKYSNVSKKDILSTLNQLTVDTIIQGLNTLPSQPKRLLICGGGAENKTLISRLQAQLS
HHHHHCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEECCCCCHHHHHHHHHHHHC
YPVKTTQSVGVPPHAIEAMMCAWLAEQRLNNTPIALQHITGATKDSVLGAVWHP
CCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA