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The map label for this gene is ntrY [H]

Identifier: 78484534

GI number: 78484534

Start: 222204

End: 224381

Strand: Reverse

Name: ntrY [H]

Synonym: Tcr_0189

Alternate gene names: 78484534

Gene position: 224381-222204 (Counterclockwise)

Preceding gene: 78484535

Following gene: 78484533

Centisome position: 9.24

GC content: 42.84

Gene sequence:

>2178_bases
ATGCCCTCAAGTCAACAATCACGCTTCCTCAAACAATATGGCTGGCTCATCGCGATTTCCAGTATCTTGTTGATCTCCCT
GATTGTTATGAGTCAAATTCTGCAAAACGCTTCGCAGTTTGCACAAACCTACTCCACCTTATTGTTCATTTCACTTGGCG
GCATGATTGTATTGATCGTAATGCTTGTACGCACCCTCCTCAAACTTCGAAAACAATACAAAGCCAATATTCCGGGCCTC
AAACTCACCGTTCGATTAACCACCATTATCGGCTTTATGTTGGGGGTCCCGCTCGCGATTATTTTTTATTTTTCAATGAG
TTTTGTTCATCAGGGAATCAACCAATGGTTTGATGTTAAAACGGAAGAAGCACTGGAAAATGCGGTCAAGCTCGTTCAAA
TCACATTAGACGATCAAACTCGGCGCAATCTCAACAACACCCAACAAGCTCTCAAGCTTTATCGGGACGAACTCTTTATC
ACCCCGGTGTTAACGCTGAATAAATTAGGGGAGCAACTGAATACGCGAGAAATCGCACTCTACAAAAGCGACGGTCAACT
CATTGCTTACAGCAGTCAGGACAATGTCAACATTTTGCCGAAATCACCGGCTCCAAGACTGTTTCAACAAATCCGTAAAA
AATTAACCTACGCCGCCATCGAAACACAGTCTGGGTTAAACACGTCTTACCAAATCATTCGGATCATGTTGCCGATTACG
GATATACACAACAATAAGCACTATGCCTTGCAAGCCGTTTTTTCGATTCCTGAACAATTAAGCCACTTAGCCGATACGGT
TCGAATTTCGGCCAGCCAATATCAAGAATTGTCTTATCTGAAAGGCCCGCTTAAAACCAGCTTTACCGTGATTTTAAGCA
TGGTGCTCTTATTAACCATGATCAGCGCCCTATTGTTTACCATCAAAACCATTCAAAACATTACCCGGCCCATTCGAACA
TTAGCGCGCGGGACAGAAGCGGTTGCAAAAGGAGATTACGCCATCTCCATGCCCGTCGTTCAAGAGGACGAAATGGGACA
ACTCATTCACTCTTTTAACGACATGATTCAGCAGATAGCCAAAGCACGAAATGACATCAAATTTGGGCACCAACAAACTG
AAATGCAGAAACTTTATCTGCAGGCGATTATTAAAAACCTAAACAGCGGTGTCTTAACGTTAGACATGAACTTACGCTTA
AAAACCATTAATGATGCCACCAATTCCATCCTCAACACCAACCTGTTTAAACAGCTTGGGAAACCACTCAATGAAATTCT
AAAACAACCTGAAAGTCATCATTTAAAACAGTTCTTTGACACCATTTTTCCTTTATTTCGAAATGATGCTAAGCCCTGGA
GTGAACAACTTACCTTTGACTGTAAAGAAGGCCAAAAAATTCTACTTGTCCATGGATCAACACTCCCCAGCCTTGACCAA
AAAGTAGGTGGGTTTGTTATTGTTATTGAAGACATCACCCAACTGGTACAAGCACAGTTGCACGCCGCTTGGAGCGACGT
CGCCCAACGCTTGGCCCATGAAATTAAAAATCCGTTAACCCCCATCCAGCTTTCCGCTGAACGGCTTAATTATAAATTAG
CCGACAAATTAATCTCATCCGACCGACGTCTACTCAATAGAATGACGGAGACCATCATTGAACAAGTTGCGGCCATGCAA
AACTTGGTTCAAGCGTTCACCGAATATGCCGACACACCAGAGATTGAGCTCAGTCAACTCAACTTGAACTCTCTCATCAA
AGATGTTGTAAGCATGTATAAAGACCCAAATGCAAACTGGAAAGTTTCTTACAAGACAGATCCACAGTGCCCTAAAATCA
CGGCGGATGCTTCAAAACTAAGGCAACTGCTACACAACCTCATTAAGAATGCCATTGAAGCCTGTGGAGAACGACCAGAA
ACACACATTGATGTCCGAACCGATTGTTCGCAAGATGCGATTAATTTTTCTATTTGTGATAATGGCCCGGGTATTCCCGA
AAAAGCCAGAAACTGGATATTTGAACCTTACTCAACCGACAAACCCAAAGGAACGGGGTTGGGGCTGGCGATAGTGAAAA
AAATTGTCGACGAACATCAAGGACAAATTCATGTAGAATCGGAACCCGAGCAAGGAACCTGTTTTATAATAAACTTACCA
CAACACACTAAAGTATAG

Upstream 100 bases:

>100_bases
CAGCGATTGGAGTAACATCCAAATTCAGTCGCCAAAAAGTTGGTTATAAACTCAATACCATGAATTATTTAATTATTTCA
ATCTTTTAAAGCAGAATTTT

Downstream 100 bases:

>100_bases
CTGTCTAATAAAATGATCCCACTATGAAACCAGGCAAATTACTGATCGTTGATGATGAAAAAGACATTCGTAGCCTCATG
CAAGAAATTTTTTCTGAAGA

Product: periplasmic sensor signal transduction histidine kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 725; Mature: 724

Protein sequence:

>725_residues
MPSSQQSRFLKQYGWLIAISSILLISLIVMSQILQNASQFAQTYSTLLFISLGGMIVLIVMLVRTLLKLRKQYKANIPGL
KLTVRLTTIIGFMLGVPLAIIFYFSMSFVHQGINQWFDVKTEEALENAVKLVQITLDDQTRRNLNNTQQALKLYRDELFI
TPVLTLNKLGEQLNTREIALYKSDGQLIAYSSQDNVNILPKSPAPRLFQQIRKKLTYAAIETQSGLNTSYQIIRIMLPIT
DIHNNKHYALQAVFSIPEQLSHLADTVRISASQYQELSYLKGPLKTSFTVILSMVLLLTMISALLFTIKTIQNITRPIRT
LARGTEAVAKGDYAISMPVVQEDEMGQLIHSFNDMIQQIAKARNDIKFGHQQTEMQKLYLQAIIKNLNSGVLTLDMNLRL
KTINDATNSILNTNLFKQLGKPLNEILKQPESHHLKQFFDTIFPLFRNDAKPWSEQLTFDCKEGQKILLVHGSTLPSLDQ
KVGGFVIVIEDITQLVQAQLHAAWSDVAQRLAHEIKNPLTPIQLSAERLNYKLADKLISSDRRLLNRMTETIIEQVAAMQ
NLVQAFTEYADTPEIELSQLNLNSLIKDVVSMYKDPNANWKVSYKTDPQCPKITADASKLRQLLHNLIKNAIEACGERPE
THIDVRTDCSQDAINFSICDNGPGIPEKARNWIFEPYSTDKPKGTGLGLAIVKKIVDEHQGQIHVESEPEQGTCFIINLP
QHTKV

Sequences:

>Translated_725_residues
MPSSQQSRFLKQYGWLIAISSILLISLIVMSQILQNASQFAQTYSTLLFISLGGMIVLIVMLVRTLLKLRKQYKANIPGL
KLTVRLTTIIGFMLGVPLAIIFYFSMSFVHQGINQWFDVKTEEALENAVKLVQITLDDQTRRNLNNTQQALKLYRDELFI
TPVLTLNKLGEQLNTREIALYKSDGQLIAYSSQDNVNILPKSPAPRLFQQIRKKLTYAAIETQSGLNTSYQIIRIMLPIT
DIHNNKHYALQAVFSIPEQLSHLADTVRISASQYQELSYLKGPLKTSFTVILSMVLLLTMISALLFTIKTIQNITRPIRT
LARGTEAVAKGDYAISMPVVQEDEMGQLIHSFNDMIQQIAKARNDIKFGHQQTEMQKLYLQAIIKNLNSGVLTLDMNLRL
KTINDATNSILNTNLFKQLGKPLNEILKQPESHHLKQFFDTIFPLFRNDAKPWSEQLTFDCKEGQKILLVHGSTLPSLDQ
KVGGFVIVIEDITQLVQAQLHAAWSDVAQRLAHEIKNPLTPIQLSAERLNYKLADKLISSDRRLLNRMTETIIEQVAAMQ
NLVQAFTEYADTPEIELSQLNLNSLIKDVVSMYKDPNANWKVSYKTDPQCPKITADASKLRQLLHNLIKNAIEACGERPE
THIDVRTDCSQDAINFSICDNGPGIPEKARNWIFEPYSTDKPKGTGLGLAIVKKIVDEHQGQIHVESEPEQGTCFIINLP
QHTKV
>Mature_724_residues
PSSQQSRFLKQYGWLIAISSILLISLIVMSQILQNASQFAQTYSTLLFISLGGMIVLIVMLVRTLLKLRKQYKANIPGLK
LTVRLTTIIGFMLGVPLAIIFYFSMSFVHQGINQWFDVKTEEALENAVKLVQITLDDQTRRNLNNTQQALKLYRDELFIT
PVLTLNKLGEQLNTREIALYKSDGQLIAYSSQDNVNILPKSPAPRLFQQIRKKLTYAAIETQSGLNTSYQIIRIMLPITD
IHNNKHYALQAVFSIPEQLSHLADTVRISASQYQELSYLKGPLKTSFTVILSMVLLLTMISALLFTIKTIQNITRPIRTL
ARGTEAVAKGDYAISMPVVQEDEMGQLIHSFNDMIQQIAKARNDIKFGHQQTEMQKLYLQAIIKNLNSGVLTLDMNLRLK
TINDATNSILNTNLFKQLGKPLNEILKQPESHHLKQFFDTIFPLFRNDAKPWSEQLTFDCKEGQKILLVHGSTLPSLDQK
VGGFVIVIEDITQLVQAQLHAAWSDVAQRLAHEIKNPLTPIQLSAERLNYKLADKLISSDRRLLNRMTETIIEQVAAMQN
LVQAFTEYADTPEIELSQLNLNSLIKDVVSMYKDPNANWKVSYKTDPQCPKITADASKLRQLLHNLIKNAIEACGERPET
HIDVRTDCSQDAINFSICDNGPGIPEKARNWIFEPYSTDKPKGTGLGLAIVKKIVDEHQGQIHVESEPEQGTCFIINLPQ
HTKV

Specific function: Member of the two-component regulatory system ntrY/ntrX involved in nitrogen level control. Probably activates ntrX by phosphorylation [H]

COG id: COG5000

COG function: function code T; Signal transduction histidine kinase involved in nitrogen fixation and metabolism regulation

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PAS (PER-ARNT-SIM) domain [H]

Homologues:

Organism=Escherichia coli, GI1788549, Length=389, Percent_Identity=25.4498714652956, Blast_Score=131, Evalue=2e-31,
Organism=Escherichia coli, GI1790300, Length=362, Percent_Identity=27.3480662983425, Blast_Score=105, Evalue=1e-23,
Organism=Escherichia coli, GI1790436, Length=220, Percent_Identity=30.9090909090909, Blast_Score=103, Evalue=6e-23,
Organism=Escherichia coli, GI1786912, Length=217, Percent_Identity=27.1889400921659, Blast_Score=85, Evalue=2e-17,
Organism=Escherichia coli, GI1786600, Length=252, Percent_Identity=28.1746031746032, Blast_Score=84, Evalue=2e-17,
Organism=Escherichia coli, GI1790861, Length=220, Percent_Identity=28.6363636363636, Blast_Score=80, Evalue=6e-16,
Organism=Escherichia coli, GI87082128, Length=256, Percent_Identity=25, Blast_Score=78, Evalue=2e-15,
Organism=Escherichia coli, GI1790346, Length=222, Percent_Identity=25.6756756756757, Blast_Score=76, Evalue=7e-15,
Organism=Escherichia coli, GI1787894, Length=226, Percent_Identity=28.3185840707965, Blast_Score=70, Evalue=4e-13,
Organism=Escherichia coli, GI1789808, Length=215, Percent_Identity=23.2558139534884, Blast_Score=69, Evalue=1e-12,
Organism=Escherichia coli, GI1786783, Length=266, Percent_Identity=28.9473684210526, Blast_Score=66, Evalue=8e-12,
Organism=Escherichia coli, GI48994928, Length=226, Percent_Identity=26.5486725663717, Blast_Score=65, Evalue=1e-11,
Organism=Escherichia coli, GI145693157, Length=125, Percent_Identity=32.8, Blast_Score=63, Evalue=5e-11,
Organism=Escherichia coli, GI1789149, Length=234, Percent_Identity=26.9230769230769, Blast_Score=63, Evalue=7e-11,
Organism=Escherichia coli, GI1788713, Length=229, Percent_Identity=24.8908296943231, Blast_Score=62, Evalue=9e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR003660
- InterPro:   IPR000014
- InterPro:   IPR013767
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082
- InterPro:   IPR017232 [H]

Pfam domain/function: PF00672 HAMP; PF02518 HATPase_c; PF00512 HisKA; PF00989 PAS [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 81959; Mature: 81828

Theoretical pI: Translated: 8.95; Mature: 8.95

Prosite motif: PS50885 HAMP ; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPSSQQSRFLKQYGWLIAISSILLISLIVMSQILQNASQFAQTYSTLLFISLGGMIVLIV
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
MLVRTLLKLRKQYKANIPGLKLTVRLTTIIGFMLGVPLAIIFYFSMSFVHQGINQWFDVK
HHHHHHHHHHHHHHCCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
TEEALENAVKLVQITLDDQTRRNLNNTQQALKLYRDELFITPVLTLNKLGEQLNTREIAL
HHHHHHHHHHEEEEEECCHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEE
YKSDGQLIAYSSQDNVNILPKSPAPRLFQQIRKKLTYAAIETQSGLNTSYQIIRIMLPIT
EECCCCEEEECCCCCCEECCCCCCHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHH
DIHNNKHYALQAVFSIPEQLSHLADTVRISASQYQELSYLKGPLKTSFTVILSMVLLLTM
HCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHH
ISALLFTIKTIQNITRPIRTLARGTEAVAKGDYAISMPVVQEDEMGQLIHSFNDMIQQIA
HHHHHHHHHHHHHHHHHHHHHHHCHHHHHCCCCEEECCCCCCHHHHHHHHHHHHHHHHHH
KARNDIKFGHQQTEMQKLYLQAIIKNLNSGVLTLDMNLRLKTINDATNSILNTNLFKQLG
HHHHHHHCCCHHHHHHHHHHHHHHHHCCCCEEEEEECEEEEECCHHHHHHHHHHHHHHHH
KPLNEILKQPESHHLKQFFDTIFPLFRNDAKPWSEQLTFDCKEGQKILLVHGSTLPSLDQ
HHHHHHHHCCHHHHHHHHHHHHHHHHCCCCCCCHHHCEEECCCCCEEEEEECCCCCCHHH
KVGGFVIVIEDITQLVQAQLHAAWSDVAQRLAHEIKNPLTPIQLSAERLNYKLADKLISS
HHCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEECHHHHHHHHHHHHHHH
DRRLLNRMTETIIEQVAAMQNLVQAFTEYADTPEIELSQLNLNSLIKDVVSMYKDPNANW
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHCCHHHHHHHHHHHHCCCCCCE
KVSYKTDPQCPKITADASKLRQLLHNLIKNAIEACGERPETHIDVRTDCSQDAINFSICD
EEEECCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCEEEEECCCCCCCCEEEEEC
NGPGIPEKARNWIFEPYSTDKPKGTGLGLAIVKKIVDEHQGQIHVESEPEQGTCFIINLP
CCCCCCHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCEEEECCCCCCCEEEEEECC
QHTKV
CCCCC
>Mature Secondary Structure 
PSSQQSRFLKQYGWLIAISSILLISLIVMSQILQNASQFAQTYSTLLFISLGGMIVLIV
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
MLVRTLLKLRKQYKANIPGLKLTVRLTTIIGFMLGVPLAIIFYFSMSFVHQGINQWFDVK
HHHHHHHHHHHHHHCCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
TEEALENAVKLVQITLDDQTRRNLNNTQQALKLYRDELFITPVLTLNKLGEQLNTREIAL
HHHHHHHHHHEEEEEECCHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEE
YKSDGQLIAYSSQDNVNILPKSPAPRLFQQIRKKLTYAAIETQSGLNTSYQIIRIMLPIT
EECCCCEEEECCCCCCEECCCCCCHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHH
DIHNNKHYALQAVFSIPEQLSHLADTVRISASQYQELSYLKGPLKTSFTVILSMVLLLTM
HCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHH
ISALLFTIKTIQNITRPIRTLARGTEAVAKGDYAISMPVVQEDEMGQLIHSFNDMIQQIA
HHHHHHHHHHHHHHHHHHHHHHHCHHHHHCCCCEEECCCCCCHHHHHHHHHHHHHHHHHH
KARNDIKFGHQQTEMQKLYLQAIIKNLNSGVLTLDMNLRLKTINDATNSILNTNLFKQLG
HHHHHHHCCCHHHHHHHHHHHHHHHHCCCCEEEEEECEEEEECCHHHHHHHHHHHHHHHH
KPLNEILKQPESHHLKQFFDTIFPLFRNDAKPWSEQLTFDCKEGQKILLVHGSTLPSLDQ
HHHHHHHHCCHHHHHHHHHHHHHHHHCCCCCCCHHHCEEECCCCCEEEEEECCCCCCHHH
KVGGFVIVIEDITQLVQAQLHAAWSDVAQRLAHEIKNPLTPIQLSAERLNYKLADKLISS
HHCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEECHHHHHHHHHHHHHHH
DRRLLNRMTETIIEQVAAMQNLVQAFTEYADTPEIELSQLNLNSLIKDVVSMYKDPNANW
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHCCHHHHHHHHHHHHCCCCCCE
KVSYKTDPQCPKITADASKLRQLLHNLIKNAIEACGERPETHIDVRTDCSQDAINFSICD
EEEECCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCEEEEECCCCCCCCEEEEEC
NGPGIPEKARNWIFEPYSTDKPKGTGLGLAIVKKIVDEHQGQIHVESEPEQGTCFIINLP
CCCCCCHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCEEEECCCCCCCEEEEEECC
QHTKV
CCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 1661370 [H]