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The map label for this gene is pip [H]

Identifier: 78484513

GI number: 78484513

Start: 198520

End: 199491

Strand: Reverse

Name: pip [H]

Synonym: Tcr_0168

Alternate gene names: 78484513

Gene position: 199491-198520 (Counterclockwise)

Preceding gene: 78484514

Following gene: 78484512

Centisome position: 8.22

GC content: 46.19

Gene sequence:

>972_bases
ATGATGACTTTAGACCAGATCTTATACCCACCGATCAAACCGTATAGCGAACATAGCTTACAGGTTGATAATACCCATTC
GCTTTACATTGAAGAAAGCGGCAATCCGTTAGGGCTTCCCGTCTTGTTTATCCATGGCGGCCCGGGGGGCGGCACCACTC
CAATGCAACGTTGTTTTTTCAATCCAGACGAATACCGTATCATCTTATTTGATCAGCGCGGGTGTGGGAAATCACGCCCT
CATGCGTGTTTAACCAATAACACCACAGCTCATTTAATTGAAGACATCGAAAAAATTCGACGTCATTTAGACATTGATCG
TTGGGTATTGTTTGGTGGTTCCTGGGGCTCAACACTGAGTTTACTCTATGCTGAAGCTTATCCAGAGCGCGTCATCTCTA
TGGTGTTACGCGGTATTTTCTTATGCCGCGAGGAAGATACCCGCTGGTTTTATCAAGAAGGTGCCAACCGATTTTACCCG
AATTACTGGCAAGATTTCATCGCCCCGGTTCCCGAAGAAAAGCGAGACGATATGATCGGCGCTTATTACGAACTCTTAAC
CAGTGAGAATGAAATTGCCCGAATGAGTGCGGCAGAAGCTTGGTCTGTTTGGGAAGGAAGAACCTCGACTCTCAAGGCCG
ATAAAGATTTGGTGAATCATTTTGGCGACCCATACCACGCACTGGCCATGGCGCGCATCGAATGTCATTATTTTAAATAC
AAAGCCTTTATCGAACCGAATCAAATTTTAGACAACATTGGCTACATTCAAAAAATTCCAACCCAAATCATTCAAGGCCG
TTACGACATGGTTTGCCCAGTAAATCAGGCCTATGCGTTATCACAGGCCATGCCGAACGCTCAACTGATTATATGCGACC
ATGCCGGCCATTCTGCTCTTGAACTGGAGATCGCTCAAGCATTGGTGGGCGCGACCGATCAAATCTATCTTGATGCGGAC
ATCTCACCTTAA

Upstream 100 bases:

>100_bases
AAAGTAGCCAGGCCTGGTCATTTTTAGGGGCTTTTTTCGTTTATAGCCTGGGGAAAAGATTCTTTTTGGTCTTCCGTACG
GTTTAGGCTAAAATTGTATT

Downstream 100 bases:

>100_bases
TATGATTTGTTTACTGCAAAGAGTGACTCACGGAAGCGTGTCGGTTTCCAATGAAACCATCGGACAGATTTCATCTGGCT
TGGTGGTGTTATGCGGATTC

Product: proline iminopeptidase

Products: NA

Alternate protein names: PIP; Prolyl aminopeptidase; PAP [H]

Number of amino acids: Translated: 323; Mature: 323

Protein sequence:

>323_residues
MMTLDQILYPPIKPYSEHSLQVDNTHSLYIEESGNPLGLPVLFIHGGPGGGTTPMQRCFFNPDEYRIILFDQRGCGKSRP
HACLTNNTTAHLIEDIEKIRRHLDIDRWVLFGGSWGSTLSLLYAEAYPERVISMVLRGIFLCREEDTRWFYQEGANRFYP
NYWQDFIAPVPEEKRDDMIGAYYELLTSENEIARMSAAEAWSVWEGRTSTLKADKDLVNHFGDPYHALAMARIECHYFKY
KAFIEPNQILDNIGYIQKIPTQIIQGRYDMVCPVNQAYALSQAMPNAQLIICDHAGHSALELEIAQALVGATDQIYLDAD
ISP

Sequences:

>Translated_323_residues
MMTLDQILYPPIKPYSEHSLQVDNTHSLYIEESGNPLGLPVLFIHGGPGGGTTPMQRCFFNPDEYRIILFDQRGCGKSRP
HACLTNNTTAHLIEDIEKIRRHLDIDRWVLFGGSWGSTLSLLYAEAYPERVISMVLRGIFLCREEDTRWFYQEGANRFYP
NYWQDFIAPVPEEKRDDMIGAYYELLTSENEIARMSAAEAWSVWEGRTSTLKADKDLVNHFGDPYHALAMARIECHYFKY
KAFIEPNQILDNIGYIQKIPTQIIQGRYDMVCPVNQAYALSQAMPNAQLIICDHAGHSALELEIAQALVGATDQIYLDAD
ISP
>Mature_323_residues
MMTLDQILYPPIKPYSEHSLQVDNTHSLYIEESGNPLGLPVLFIHGGPGGGTTPMQRCFFNPDEYRIILFDQRGCGKSRP
HACLTNNTTAHLIEDIEKIRRHLDIDRWVLFGGSWGSTLSLLYAEAYPERVISMVLRGIFLCREEDTRWFYQEGANRFYP
NYWQDFIAPVPEEKRDDMIGAYYELLTSENEIARMSAAEAWSVWEGRTSTLKADKDLVNHFGDPYHALAMARIECHYFKY
KAFIEPNQILDNIGYIQKIPTQIIQGRYDMVCPVNQAYALSQAMPNAQLIICDHAGHSALELEIAQALVGATDQIYLDAD
ISP

Specific function: Specifically catalyzes the removal of N-terminal proline residues from peptides [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase S33 family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000073
- InterPro:   IPR005944
- InterPro:   IPR002410 [H]

Pfam domain/function: PF00561 Abhydrolase_1 [H]

EC number: =3.4.11.5 [H]

Molecular weight: Translated: 36847; Mature: 36847

Theoretical pI: Translated: 4.86; Mature: 4.86

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.2 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
5.0 %Cys+Met (Translated Protein)
2.2 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
5.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MMTLDQILYPPIKPYSEHSLQVDNTHSLYIEESGNPLGLPVLFIHGGPGGGTTPMQRCFF
CCCHHHHHCCCCCCCCCCCEEECCCEEEEEECCCCCCCEEEEEEEECCCCCCCHHHHHCC
NPDEYRIILFDQRGCGKSRPHACLTNNTTAHLIEDIEKIRRHLDIDRWVLFGGSWGSTLS
CCCCEEEEEEECCCCCCCCCCEEECCCCHHHHHHHHHHHHHHCCCCEEEEECCCCCHHHH
LLYAEAYPERVISMVLRGIFLCREEDTRWFYQEGANRFYPNYWQDFIAPVPEEKRDDMIG
HHHHHHHHHHHHHHHHHHHHEECCCCCHHHHHCCCCCCCCHHHHHHHCCCCCCHHHHHHH
AYYELLTSENEIARMSAAEAWSVWEGRTSTLKADKDLVNHFGDPYHALAMARIECHYFKY
HHHHHHCCCCHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHCCCHHHHHHHHHHHEEEEEE
KAFIEPNQILDNIGYIQKIPTQIIQGRYDMVCPVNQAYALSQAMPNAQLIICDHAGHSAL
EEEECHHHHHHHHHHHHHHHHHHHCCCCCEECCCHHHHHHHHCCCCCEEEEEECCCCCHH
ELEIAQALVGATDQIYLDADISP
HHHHHHHHHCCCCEEEEECCCCC
>Mature Secondary Structure
MMTLDQILYPPIKPYSEHSLQVDNTHSLYIEESGNPLGLPVLFIHGGPGGGTTPMQRCFF
CCCHHHHHCCCCCCCCCCCEEECCCEEEEEECCCCCCCEEEEEEEECCCCCCCHHHHHCC
NPDEYRIILFDQRGCGKSRPHACLTNNTTAHLIEDIEKIRRHLDIDRWVLFGGSWGSTLS
CCCCEEEEEEECCCCCCCCCCEEECCCCHHHHHHHHHHHHHHCCCCEEEEECCCCCHHHH
LLYAEAYPERVISMVLRGIFLCREEDTRWFYQEGANRFYPNYWQDFIAPVPEEKRDDMIG
HHHHHHHHHHHHHHHHHHHHEECCCCCHHHHHCCCCCCCCHHHHHHHCCCCCCHHHHHHH
AYYELLTSENEIARMSAAEAWSVWEGRTSTLKADKDLVNHFGDPYHALAMARIECHYFKY
HHHHHHCCCCHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHCCCHHHHHHHHHHHEEEEEE
KAFIEPNQILDNIGYIQKIPTQIIQGRYDMVCPVNQAYALSQAMPNAQLIICDHAGHSAL
EEEECHHHHHHHHHHHHHHHHHHHCCCCCEECCCHHHHHHHHCCCCCEEEEEECCCCCHH
ELEIAQALVGATDQIYLDADISP
HHHHHHHHHCCCCEEEEECCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA