Click here to switch to the map view.

The map label for this gene is yciR [C]

Identifier: 78484511

GI number: 78484511

Start: 195891

End: 197984

Strand: Reverse

Name: yciR [C]

Synonym: Tcr_0166

Alternate gene names: 78484511

Gene position: 197984-195891 (Counterclockwise)

Preceding gene: 78484512

Following gene: 78484510

Centisome position: 8.16

GC content: 42.93

Gene sequence:

>2094_bases
ATGCCACTTTCTGAGACAAGCTCTAAGCAGATTGATCCCACTTTAATCCTCGTTGTTGAAGACGACGATACCACTCGCTT
GACCCTCAATAAGGTCTTAACCAAATCCGGATTTAAAGTCATTGATGCCAAAGATGGCCAAGACGGCTTTTCAAAGTTTA
TCAATGAATCTCCCTGTTTGATACTCATGGATGTGATGATGCCCATTATGGATGGCTATGCCGCCACAGAAGCCATTCGA
AACTATGAAAAAACCCGTGCGGTTCCGATCTTAATGTTAACACCGCAAGATGACATGGGCTCAATCGATCATGCGTTTAC
CAGTGGTGCGACGGACTTTATTACCAAACCGATCAACTGGTCCTTGTTAAGTCAGCGTGTTAAATATGCCATTAACTCTT
CTTTAATCGAAGATCAATTACGGACCAGTCAGTCGCAACTTATGTACGCCCAAAAACTGGCGAAACTTGGCTATTGGGAA
TGGGATACCAAGGCCGACCAAGTCACCGGAACCGGATCCGCTTTTGAACTGTTTGGCATTCCCAATCAGGCAGATGTCAC
TTTGGAACAATTCTTTTCCAATATTATTCCGAAAGACTTGCCATTAATCCAGCAAGCCATTGCGGACGCCAGCCAAGGGT
ATAACGATATCCAAGTCAGTTTCCGAGTCCTGCATCATGACAACTCTCTATCTCACGTGGATTGTTTGGGCGAAGTCAGC
TTTGATGAACATGGTGACATTTCCAGAATCACTGGTTCCGCGCAGGATATCAGTCGCTTACATAAAGCGGAAACACTGAT
TGATTACCAGTCCAGCCACGATAAGTTGACGGACTTGGCCAACCGCTCATTCTTTAACAAAAACCTAGCGAATTTTATAA
AAGAAGCCAACCCTAAAAAATACAGTGCCACGGTGATACTCGATATTGACCGTTTCAAAAAAATCAATGATAACTTAGGT
CAAGAAAATGGTGATGCACTGCTTCGAACCGTTGCACAACGCTTAAAGAAAGTGACGCGAGAAGATGACTTTGTTGCCCG
ATTAGGAAGTGATGAATTCGCTATCTTAATTAAAAATACAGAAGATGCTCAAGAATTAAACTTATCCCTCAGCCGTATTT
TTCATGACATTTCAAAAGCCTTTAATGTTAAAGATCAAGAGCTGTTTATCACGTTCTCTATCGGTATCAGTATCATTAAC
CAAGACGGCGATCAAGCCAGTGAGCTGATAGCCCACGCGAACATTGCTCGAAGCCAAGCCAAACTCAAAGGCGGCAATCA
GTTTTTATTCTATCAGGCAGAAATGAATGCCGAATCGAAAGAGCAACTGATGCTCGAGAACGATTTAAGAAAAGCACTTG
ATCGCAATGAAATTGAGGTTTATTACCAACCCCAGATTGATGGCCATTCTTTAAAACCTTATGGTGCAGAAGCATTGGTG
CGCTGGAAACATCCGACGGAAGGCATTATTTCTCCCGGCATCTTTATTCCAATGGCCGAAAGCAATGGCATGATTGTCGA
CATTGGTCGATTTGTTTTAGAAAATGCCATCAAAGAAGCCGAAAAGTGGCATGCTGAAGGGTTTGATGAAATGCGCATTG
CCGTTAACTTATCGGGCCGACAATTTTCCAGTTCAAATCTGATTAAAGAAGTGCAAGAAGTTTTACAAAACACAACGCTG
CCCGCCAAATACCTTGATTTGGAAATCACAGAAAGTTTGGCTATGAGTAATGCCGATCACAACATCAGCATTCTAAAGGG
ACTGAAAGCCATGGGCGTTTCATTGTCGATTGATGACTTCGGGACTGGCTACTCTTCTCTCGCGTATTTGCACAGTTTCC
CAATCGATGCGATTAAAATCGACCGTTCCTTTATCGATAACTTGGAAAGCCAGGAAGGGCAAGCCATTGTCAGAACAATC
TTGGCCATGGCCGACAGCTTAAGTCTAAAAGTGGTTGCTGAAGGGATCGAAGAAGAATTTCATGTTACTTTCCTTCAAAA
TAAGAACTGTGATATTTTCCAAGGCTTCATGTTCGGTAAACCGATGCCTGCGGGAGATTTTCAACAGTATCTTAAATCTC
AAAAAGCGTCGTAG

Upstream 100 bases:

>100_bases
TTGGCTTGAAACCTAATTCCTTCAAAAGGCGTAAGGGTTTTAATTTCGACAAAAAGCGGCTACACTTAGCCAAACAACTT
AACGGTGATACGAACTCCTC

Downstream 100 bases:

>100_bases
TAAGCTATAATATTTTTCATAGAACAGGAAAAAAATCATGTCTGATCCGGTTAATACAGAGAATTTAAGTCAGTTAAAAA
CACTGATCGGAGAAGACCTA

Product: response regulator receiver/GGDEF/EAL domain-containing protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 697; Mature: 696

Protein sequence:

>697_residues
MPLSETSSKQIDPTLILVVEDDDTTRLTLNKVLTKSGFKVIDAKDGQDGFSKFINESPCLILMDVMMPIMDGYAATEAIR
NYEKTRAVPILMLTPQDDMGSIDHAFTSGATDFITKPINWSLLSQRVKYAINSSLIEDQLRTSQSQLMYAQKLAKLGYWE
WDTKADQVTGTGSAFELFGIPNQADVTLEQFFSNIIPKDLPLIQQAIADASQGYNDIQVSFRVLHHDNSLSHVDCLGEVS
FDEHGDISRITGSAQDISRLHKAETLIDYQSSHDKLTDLANRSFFNKNLANFIKEANPKKYSATVILDIDRFKKINDNLG
QENGDALLRTVAQRLKKVTREDDFVARLGSDEFAILIKNTEDAQELNLSLSRIFHDISKAFNVKDQELFITFSIGISIIN
QDGDQASELIAHANIARSQAKLKGGNQFLFYQAEMNAESKEQLMLENDLRKALDRNEIEVYYQPQIDGHSLKPYGAEALV
RWKHPTEGIISPGIFIPMAESNGMIVDIGRFVLENAIKEAEKWHAEGFDEMRIAVNLSGRQFSSSNLIKEVQEVLQNTTL
PAKYLDLEITESLAMSNADHNISILKGLKAMGVSLSIDDFGTGYSSLAYLHSFPIDAIKIDRSFIDNLESQEGQAIVRTI
LAMADSLSLKVVAEGIEEEFHVTFLQNKNCDIFQGFMFGKPMPAGDFQQYLKSQKAS

Sequences:

>Translated_697_residues
MPLSETSSKQIDPTLILVVEDDDTTRLTLNKVLTKSGFKVIDAKDGQDGFSKFINESPCLILMDVMMPIMDGYAATEAIR
NYEKTRAVPILMLTPQDDMGSIDHAFTSGATDFITKPINWSLLSQRVKYAINSSLIEDQLRTSQSQLMYAQKLAKLGYWE
WDTKADQVTGTGSAFELFGIPNQADVTLEQFFSNIIPKDLPLIQQAIADASQGYNDIQVSFRVLHHDNSLSHVDCLGEVS
FDEHGDISRITGSAQDISRLHKAETLIDYQSSHDKLTDLANRSFFNKNLANFIKEANPKKYSATVILDIDRFKKINDNLG
QENGDALLRTVAQRLKKVTREDDFVARLGSDEFAILIKNTEDAQELNLSLSRIFHDISKAFNVKDQELFITFSIGISIIN
QDGDQASELIAHANIARSQAKLKGGNQFLFYQAEMNAESKEQLMLENDLRKALDRNEIEVYYQPQIDGHSLKPYGAEALV
RWKHPTEGIISPGIFIPMAESNGMIVDIGRFVLENAIKEAEKWHAEGFDEMRIAVNLSGRQFSSSNLIKEVQEVLQNTTL
PAKYLDLEITESLAMSNADHNISILKGLKAMGVSLSIDDFGTGYSSLAYLHSFPIDAIKIDRSFIDNLESQEGQAIVRTI
LAMADSLSLKVVAEGIEEEFHVTFLQNKNCDIFQGFMFGKPMPAGDFQQYLKSQKAS
>Mature_696_residues
PLSETSSKQIDPTLILVVEDDDTTRLTLNKVLTKSGFKVIDAKDGQDGFSKFINESPCLILMDVMMPIMDGYAATEAIRN
YEKTRAVPILMLTPQDDMGSIDHAFTSGATDFITKPINWSLLSQRVKYAINSSLIEDQLRTSQSQLMYAQKLAKLGYWEW
DTKADQVTGTGSAFELFGIPNQADVTLEQFFSNIIPKDLPLIQQAIADASQGYNDIQVSFRVLHHDNSLSHVDCLGEVSF
DEHGDISRITGSAQDISRLHKAETLIDYQSSHDKLTDLANRSFFNKNLANFIKEANPKKYSATVILDIDRFKKINDNLGQ
ENGDALLRTVAQRLKKVTREDDFVARLGSDEFAILIKNTEDAQELNLSLSRIFHDISKAFNVKDQELFITFSIGISIINQ
DGDQASELIAHANIARSQAKLKGGNQFLFYQAEMNAESKEQLMLENDLRKALDRNEIEVYYQPQIDGHSLKPYGAEALVR
WKHPTEGIISPGIFIPMAESNGMIVDIGRFVLENAIKEAEKWHAEGFDEMRIAVNLSGRQFSSSNLIKEVQEVLQNTTLP
AKYLDLEITESLAMSNADHNISILKGLKAMGVSLSIDDFGTGYSSLAYLHSFPIDAIKIDRSFIDNLESQEGQAIVRTIL
AMADSLSLKVVAEGIEEEFHVTFLQNKNCDIFQGFMFGKPMPAGDFQQYLKSQKAS

Specific function: Unknown

COG id: COG5001

COG function: function code T; Predicted signal transduction protein containing a membrane domain, an EAL and a GGDEF domain

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 MHYT domain [H]

Homologues:

Organism=Escherichia coli, GI1787541, Length=441, Percent_Identity=36.281179138322, Blast_Score=289, Evalue=4e-79,
Organism=Escherichia coli, GI87081921, Length=444, Percent_Identity=33.3333333333333, Blast_Score=239, Evalue=5e-64,
Organism=Escherichia coli, GI226510982, Length=457, Percent_Identity=26.6958424507659, Blast_Score=181, Evalue=2e-46,
Organism=Escherichia coli, GI1790496, Length=252, Percent_Identity=34.5238095238095, Blast_Score=159, Evalue=6e-40,
Organism=Escherichia coli, GI87081980, Length=251, Percent_Identity=31.8725099601594, Blast_Score=148, Evalue=1e-36,
Organism=Escherichia coli, GI1788502, Length=248, Percent_Identity=32.6612903225806, Blast_Score=146, Evalue=4e-36,
Organism=Escherichia coli, GI1787055, Length=455, Percent_Identity=27.032967032967, Blast_Score=145, Evalue=1e-35,
Organism=Escherichia coli, GI87081845, Length=250, Percent_Identity=32.8, Blast_Score=140, Evalue=2e-34,
Organism=Escherichia coli, GI1786507, Length=237, Percent_Identity=32.0675105485232, Blast_Score=130, Evalue=2e-31,
Organism=Escherichia coli, GI87081743, Length=245, Percent_Identity=29.7959183673469, Blast_Score=127, Evalue=2e-30,
Organism=Escherichia coli, GI1788381, Length=473, Percent_Identity=26.215644820296, Blast_Score=117, Evalue=2e-27,
Organism=Escherichia coli, GI1788849, Length=256, Percent_Identity=33.59375, Blast_Score=112, Evalue=8e-26,
Organism=Escherichia coli, GI87082096, Length=253, Percent_Identity=30.4347826086957, Blast_Score=104, Evalue=2e-23,
Organism=Escherichia coli, GI1787410, Length=131, Percent_Identity=34.3511450381679, Blast_Score=76, Evalue=9e-15,
Organism=Escherichia coli, GI1786584, Length=176, Percent_Identity=26.1363636363636, Blast_Score=74, Evalue=2e-14,
Organism=Escherichia coli, GI145693134, Length=179, Percent_Identity=31.2849162011173, Blast_Score=74, Evalue=3e-14,
Organism=Escherichia coli, GI1787262, Length=190, Percent_Identity=28.4210526315789, Blast_Score=74, Evalue=4e-14,
Organism=Escherichia coli, GI87082012, Length=127, Percent_Identity=33.8582677165354, Blast_Score=74, Evalue=5e-14,
Organism=Escherichia coli, GI1788956, Length=143, Percent_Identity=30.0699300699301, Blast_Score=71, Evalue=3e-13,
Organism=Escherichia coli, GI87081977, Length=167, Percent_Identity=30.5389221556886, Blast_Score=70, Evalue=4e-13,
Organism=Escherichia coli, GI1788550, Length=146, Percent_Identity=28.0821917808219, Blast_Score=70, Evalue=5e-13,
Organism=Escherichia coli, GI1787816, Length=167, Percent_Identity=29.940119760479, Blast_Score=69, Evalue=1e-12,
Organism=Escherichia coli, GI87081881, Length=263, Percent_Identity=23.1939163498099, Blast_Score=68, Evalue=2e-12,
Organism=Escherichia coli, GI1789650, Length=434, Percent_Identity=20.5069124423963, Blast_Score=68, Evalue=3e-12,
Organism=Escherichia coli, GI87082007, Length=235, Percent_Identity=26.3829787234043, Blast_Score=67, Evalue=4e-12,
Organism=Escherichia coli, GI1787802, Length=131, Percent_Identity=29.7709923664122, Blast_Score=66, Evalue=6e-12,
Organism=Escherichia coli, GI1788085, Length=166, Percent_Identity=27.1084337349398, Blast_Score=65, Evalue=1e-11,
Organism=Escherichia coli, GI1786599, Length=113, Percent_Identity=32.7433628318584, Blast_Score=65, Evalue=2e-11,
Organism=Escherichia coli, GI1786784, Length=195, Percent_Identity=27.1794871794872, Blast_Score=65, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001054
- InterPro:   IPR000160
- InterPro:   IPR001633
- InterPro:   IPR005330 [H]

Pfam domain/function: PF00563 EAL; PF00990 GGDEF; PF03707 MHYT [H]

EC number: NA

Molecular weight: Translated: 77968; Mature: 77837

Theoretical pI: Translated: 4.71; Mature: 4.71

Prosite motif: PS50110 RESPONSE_REGULATORY ; PS50883 EAL ; PS50887 GGDEF

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPLSETSSKQIDPTLILVVEDDDTTRLTLNKVLTKSGFKVIDAKDGQDGFSKFINESPCL
CCCCCCCCCCCCCEEEEEEECCCCCEEEHHHHHHHCCCEEEECCCCHHHHHHHCCCCCHH
ILMDVMMPIMDGYAATEAIRNYEKTRAVPILMLTPQDDMGSIDHAFTSGATDFITKPINW
HHHHHHHHHHCCHHHHHHHHHHHHHCCEEEEEECCCCCCCCHHHHHHCCCHHHHCCCCCH
SLLSQRVKYAINSSLIEDQLRTSQSQLMYAQKLAKLGYWEWDTKADQVTGTGSAFELFGI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCEEEEECC
PNQADVTLEQFFSNIIPKDLPLIQQAIADASQGYNDIQVSFRVLHHDNSLSHVDCLGEVS
CCCCCHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCEEEEEEEEEECCCCCCHHHHHCCCC
FDEHGDISRITGSAQDISRLHKAETLIDYQSSHDKLTDLANRSFFNKNLANFIKEANPKK
CCCCCCHHHHCCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCC
YSATVILDIDRFKKINDNLGQENGDALLRTVAQRLKKVTREDDFVARLGSDEFAILIKNT
EEEEEEEEHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHCCCCHHHHCCCCCEEEEEECC
EDAQELNLSLSRIFHDISKAFNVKDQELFITFSIGISIINQDGDQASELIAHANIARSQA
CCHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEEEEEEEEECCCHHHHHHHHHHHHHHHHH
KLKGGNQFLFYQAEMNAESKEQLMLENDLRKALDRNEIEVYYQPQIDGHSLKPYGAEALV
HCCCCCEEEEEEECCCCCHHHHHHHHHHHHHHCCCCCEEEEECCCCCCCCCCCCCCCCEE
RWKHPTEGIISPGIFIPMAESNGMIVDIGRFVLENAIKEAEKWHAEGFDEMRIAVNLSGR
EECCCCCCCCCCCEEEEEECCCCEEEEHHHHHHHHHHHHHHHHHHCCCCEEEEEEEECCC
QFSSSNLIKEVQEVLQNTTLPAKYLDLEITESLAMSNADHNISILKGLKAMGVSLSIDDF
CCCHHHHHHHHHHHHHCCCCCHHHCCHHHHHHHHHCCCCCCHHHHHHHHHHCCEEEECCC
GTGYSSLAYLHSFPIDAIKIDRSFIDNLESQEGQAIVRTILAMADSLSLKVVAEGIEEEF
CCCHHHHHHHHHCCCCCEEECHHHHHCCCCCCCHHHHHHHHHHHCCCHHHHHHHCCCCCE
HVTFLQNKNCDIFQGFMFGKPMPAGDFQQYLKSQKAS
EEEEEECCCCCEEEHHHCCCCCCCHHHHHHHHHCCCC
>Mature Secondary Structure 
PLSETSSKQIDPTLILVVEDDDTTRLTLNKVLTKSGFKVIDAKDGQDGFSKFINESPCL
CCCCCCCCCCCCEEEEEEECCCCCEEEHHHHHHHCCCEEEECCCCHHHHHHHCCCCCHH
ILMDVMMPIMDGYAATEAIRNYEKTRAVPILMLTPQDDMGSIDHAFTSGATDFITKPINW
HHHHHHHHHHCCHHHHHHHHHHHHHCCEEEEEECCCCCCCCHHHHHHCCCHHHHCCCCCH
SLLSQRVKYAINSSLIEDQLRTSQSQLMYAQKLAKLGYWEWDTKADQVTGTGSAFELFGI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCEEEEECC
PNQADVTLEQFFSNIIPKDLPLIQQAIADASQGYNDIQVSFRVLHHDNSLSHVDCLGEVS
CCCCCHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCEEEEEEEEEECCCCCCHHHHHCCCC
FDEHGDISRITGSAQDISRLHKAETLIDYQSSHDKLTDLANRSFFNKNLANFIKEANPKK
CCCCCCHHHHCCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCC
YSATVILDIDRFKKINDNLGQENGDALLRTVAQRLKKVTREDDFVARLGSDEFAILIKNT
EEEEEEEEHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHCCCCHHHHCCCCCEEEEEECC
EDAQELNLSLSRIFHDISKAFNVKDQELFITFSIGISIINQDGDQASELIAHANIARSQA
CCHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEEEEEEEEECCCHHHHHHHHHHHHHHHHH
KLKGGNQFLFYQAEMNAESKEQLMLENDLRKALDRNEIEVYYQPQIDGHSLKPYGAEALV
HCCCCCEEEEEEECCCCCHHHHHHHHHHHHHHCCCCCEEEEECCCCCCCCCCCCCCCCEE
RWKHPTEGIISPGIFIPMAESNGMIVDIGRFVLENAIKEAEKWHAEGFDEMRIAVNLSGR
EECCCCCCCCCCCEEEEEECCCCEEEEHHHHHHHHHHHHHHHHHHCCCCEEEEEEEECCC
QFSSSNLIKEVQEVLQNTTLPAKYLDLEITESLAMSNADHNISILKGLKAMGVSLSIDDF
CCCHHHHHHHHHHHHHCCCCCHHHCCHHHHHHHHHCCCCCCHHHHHHHHHHCCEEEECCC
GTGYSSLAYLHSFPIDAIKIDRSFIDNLESQEGQAIVRTILAMADSLSLKVVAEGIEEEF
CCCHHHHHHHHHCCCCCEEECHHHHHCCCCCCCHHHHHHHHHHHCCCHHHHHHHCCCCCE
HVTFLQNKNCDIFQGFMFGKPMPAGDFQQYLKSQKAS
EEEEEECCCCCEEEHHHCCCCCCCHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 10984043 [H]