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The map label for this gene is thiO [H]

Identifier: 78484492

GI number: 78484492

Start: 178254

End: 179306

Strand: Reverse

Name: thiO [H]

Synonym: Tcr_0147

Alternate gene names: 78484492

Gene position: 179306-178254 (Counterclockwise)

Preceding gene: 78484493

Following gene: 78484491

Centisome position: 7.39

GC content: 50.14

Gene sequence:

>1053_bases
ATGACAACACAAACCATCGGCATTGCCGGGGCTGGACTCGTCGGTCGTATTTTAGCACTGAATTTGATCAGGCTCGGTCA
CAACGTGACCTTATTTGAAAAGGATTCGTATGCGTCTGAAAATGCCGCCGGGTTGGTGGCCGCCGGGATGCTAGCGCCTT
TTGCCGAACTCGAGACGGCCGAGTCCGCCATATTTGATTCCGGCATGCGCTCCATTCAACTTTGGCCTGAGCTGCTGACG
CAGATAAAGATTCCTGATGCGTTTCAACAGCAAGGCAGTTTGATCACCGCCCACCGGGCGGACATGCCAGAATTAGCGCA
CTTTATTGCTCAATTACAATCAAAAATTCCGGCGGCCGCATCCATAGAGACGTTAAATCAATCAGGAATTTTGGCTTTGG
AGCCTGAGCTCAGTCAGCATACAAAGGCGTTTTTTCTACCCACGGAAGGGCAGGTCAATGCGCAACAGTTCATGGAAAAA
AGCGCGGCTTTCTTAAAAGAGCATCCCTCTGTTCAATGGAAAACGTATCAAGCCGTGTCCCGAGTCTCTAACGGCCAGAT
CGAAACCAGCGACACCTGTGTTGATTTCGATTGGGTCTTTGATGCCAGAGGCTTAGGAGCGAAACCCGATATTTCGGATC
TTCGAGGCGTTAGAGGGGAAGTGTTTTGGCTCGATGCGCCGGATGTATCGCTTTCACGACCGGTGCGCTTAATGCATCCG
CGTTATCGAATTTACATTGTGCCACGCCCCAATCATCGCTACGTGGTGGGGGCCACGGAAATTGAAAGTGAAGATCAAAG
CGACATGTCTGTACGCTCCAGTTTGGAGCTGCTTTCAGCTGTGTACAGCGTACATTCAGGGTTCGGAGAAGCGCGTATTG
TCAACATGCTCACCAACTGTCGCCCCGCATTAAAAGATAATTTACCCCGAATCATACATGAAGACAAAACCACGCGCATT
AATGGCTTATACCGCCATGGTTATTTATTGGCGCCTGCGGTGGTTGAAAAGGCTTTAAACGAAACCCCTTTCATGTCTGA
TTCAGCGGCTTAG

Upstream 100 bases:

>100_bases
TGAAGTGTACGTTAACGTCGAAGACATCACAAAAACAGGTTCTTAACCCCTATTATGCACGTCGTTGCGGCCCTTGTTGT
CGCAACGCGAGGAGTTGATT

Downstream 100 bases:

>100_bases
TCTTAACTTAAAAGGAAGGACATATGACCACCATTACTGTCCAGATCAATGATGAGATAAAGGCGATCCCCGCCTCGTTG
TCTTTGACCGATCTGTTAAA

Product: FAD dependent oxidoreductase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 350; Mature: 349

Protein sequence:

>350_residues
MTTQTIGIAGAGLVGRILALNLIRLGHNVTLFEKDSYASENAAGLVAAGMLAPFAELETAESAIFDSGMRSIQLWPELLT
QIKIPDAFQQQGSLITAHRADMPELAHFIAQLQSKIPAAASIETLNQSGILALEPELSQHTKAFFLPTEGQVNAQQFMEK
SAAFLKEHPSVQWKTYQAVSRVSNGQIETSDTCVDFDWVFDARGLGAKPDISDLRGVRGEVFWLDAPDVSLSRPVRLMHP
RYRIYIVPRPNHRYVVGATEIESEDQSDMSVRSSLELLSAVYSVHSGFGEARIVNMLTNCRPALKDNLPRIIHEDKTTRI
NGLYRHGYLLAPAVVEKALNETPFMSDSAA

Sequences:

>Translated_350_residues
MTTQTIGIAGAGLVGRILALNLIRLGHNVTLFEKDSYASENAAGLVAAGMLAPFAELETAESAIFDSGMRSIQLWPELLT
QIKIPDAFQQQGSLITAHRADMPELAHFIAQLQSKIPAAASIETLNQSGILALEPELSQHTKAFFLPTEGQVNAQQFMEK
SAAFLKEHPSVQWKTYQAVSRVSNGQIETSDTCVDFDWVFDARGLGAKPDISDLRGVRGEVFWLDAPDVSLSRPVRLMHP
RYRIYIVPRPNHRYVVGATEIESEDQSDMSVRSSLELLSAVYSVHSGFGEARIVNMLTNCRPALKDNLPRIIHEDKTTRI
NGLYRHGYLLAPAVVEKALNETPFMSDSAA
>Mature_349_residues
TTQTIGIAGAGLVGRILALNLIRLGHNVTLFEKDSYASENAAGLVAAGMLAPFAELETAESAIFDSGMRSIQLWPELLTQ
IKIPDAFQQQGSLITAHRADMPELAHFIAQLQSKIPAAASIETLNQSGILALEPELSQHTKAFFLPTEGQVNAQQFMEKS
AAFLKEHPSVQWKTYQAVSRVSNGQIETSDTCVDFDWVFDARGLGAKPDISDLRGVRGEVFWLDAPDVSLSRPVRLMHPR
YRIYIVPRPNHRYVVGATEIESEDQSDMSVRSSLELLSAVYSVHSGFGEARIVNMLTNCRPALKDNLPRIIHEDKTTRIN
GLYRHGYLLAPAVVEKALNETPFMSDSAA

Specific function: May have amino acid oxidase activity in the biosynthesis of thiazole when cysteine gives its thiol group to be inserted into the thiazole molecule and the rest of the molecule is deaminated to give pyruvic acid and ammonia [H]

COG id: COG0665

COG function: function code E; Glycine/D-amino acid oxidases (deaminating)

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006076
- InterPro:   IPR012727 [H]

Pfam domain/function: PF01266 DAO [H]

EC number: NA

Molecular weight: Translated: 38544; Mature: 38413

Theoretical pI: Translated: 5.80; Mature: 5.80

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTTQTIGIAGAGLVGRILALNLIRLGHNVTLFEKDSYASENAAGLVAAGMLAPFAELETA
CCCCEEECCCCHHHHHHHHHHHHHHCCCEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHH
ESAIFDSGMRSIQLWPELLTQIKIPDAFQQQGSLITAHRADMPELAHFIAQLQSKIPAAA
HHHHHHHCCHHHHHHHHHHHHCCCCHHHHHCCCEEEECCCCCHHHHHHHHHHHHHCCCHH
SIETLNQSGILALEPELSQHTKAFFLPTEGQVNAQQFMEKSAAFLKEHPSVQWKTYQAVS
HHHHHCCCCEEEECCCHHHCCEEEEECCCCCCCHHHHHHHHHHHHHHCCCCCCHHHHHHH
RVSNGQIETSDTCVDFDWVFDARGLGAKPDISDLRGVRGEVFWLDAPDVSLSRPVRLMHP
HHCCCCEECCCCEEEEEEEECCCCCCCCCCHHHHCCCCCEEEEEECCCCCCCCCCHHCCC
RYRIYIVPRPNHRYVVGATEIESEDQSDMSVRSSLELLSAVYSVHSGFGEARIVNMLTNC
CEEEEEEECCCCCEEEECHHCCCCCCHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHC
RPALKDNLPRIIHEDKTTRINGLYRHGYLLAPAVVEKALNETPFMSDSAA
CHHHHCCCCHHHHCCCCHHEEEEECCCEEEHHHHHHHHHCCCCCCCCCCC
>Mature Secondary Structure 
TTQTIGIAGAGLVGRILALNLIRLGHNVTLFEKDSYASENAAGLVAAGMLAPFAELETA
CCCEEECCCCHHHHHHHHHHHHHHCCCEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHH
ESAIFDSGMRSIQLWPELLTQIKIPDAFQQQGSLITAHRADMPELAHFIAQLQSKIPAAA
HHHHHHHCCHHHHHHHHHHHHCCCCHHHHHCCCEEEECCCCCHHHHHHHHHHHHHCCCHH
SIETLNQSGILALEPELSQHTKAFFLPTEGQVNAQQFMEKSAAFLKEHPSVQWKTYQAVS
HHHHHCCCCEEEECCCHHHCCEEEEECCCCCCCHHHHHHHHHHHHHHCCCCCCHHHHHHH
RVSNGQIETSDTCVDFDWVFDARGLGAKPDISDLRGVRGEVFWLDAPDVSLSRPVRLMHP
HHCCCCEECCCCEEEEEEEECCCCCCCCCCHHHHCCCCCEEEEEECCCCCCCCCCHHCCC
RYRIYIVPRPNHRYVVGATEIESEDQSDMSVRSSLELLSAVYSVHSGFGEARIVNMLTNC
CEEEEEEECCCCCEEEECHHCCCCCCHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHC
RPALKDNLPRIIHEDKTTRINGLYRHGYLLAPAVVEKALNETPFMSDSAA
CHHHHCCCCHHHHCCCCHHEEEEECCCEEEHHHHHHHHHCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9371431 [H]