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The map label for this gene is nagD [C]

Identifier: 78484487

GI number: 78484487

Start: 174845

End: 175609

Strand: Reverse

Name: nagD [C]

Synonym: Tcr_0142

Alternate gene names: 78484487

Gene position: 175609-174845 (Counterclockwise)

Preceding gene: 78484488

Following gene: 78484486

Centisome position: 7.23

GC content: 43.4

Gene sequence:

>765_bases
ATGACTTCTCCTTCCATCCAAAATATTAAAGCCGTATTATTTGATCTAAGCGGTGTTCTCTATATCGGCACGGATGCCCT
CCCTGGTGCGGTTGAAACGGTACATCGTCTAAAACAACAAGGTTTTATTCTGCGTTTTGTAACCAATACAGCCAGTCAAC
CCAGTGAAATGATTTTACGACAACTGAACCAGCTTGGATTTGACGTGGAAGAAGCGGAACTTTATACCGCACCGAAAGCC
GCCAAACAGTATCTTTTACACCATCAACTTCGGCCATACTGCTTAATCCATACATTGTTAAAAGCCGAATTTAAAGACAT
CGATCAAACCAATCCAAATTGCGTATTGCTGGGAGATGCTCAAGACGACTTAACCTATCAAAGCTTGAACAAGGCCTTCA
ATTTGGTTGAAAAGGGTTACCCATTAATTGGTATTGGCAAAAATAAATATTACAAAGATGCCGAAGGCTTCAAACTGGAC
GCAGGTACGTTTATTCATGCTTTGGAATGGGCCAGTGATACACACGCCATTATCACCGGAAAACCGGATAAGACTTTTTT
TGACGAGGTCGTGGCTTCTACAGGTGTGCCTGCGACTCAATGCTTGATGATTGGTGACGATGTTCGTGGTGATGTTGAAG
GCGCCATTAACGCGGGCTTGCAGGCGGCGTTGGTTCGAACAGGAAAATTCAAACCCAGCGATGAAAAAATTCTGCCTGAT
ACAGCCTGGATACTGGATGGCATTCAAAAGCTTTCCTTATCATAA

Upstream 100 bases:

>100_bases
CTTGAACTTGGGCACGGAACCGTCAAACAATTAATAAGGCACTTCGTTTCACTTAGTCTTTTTGCTAAGATTGACTCTCC
TATTCTGAAAGGTGATGATC

Downstream 100 bases:

>100_bases
AATACGCTTAATGCCGTTAAATGAATTTAAAATACCTAAATTACTCTTAAAAATAAAAAATGGAATTTATATGAAACCCC
TTTACACGCTTATTTTAAGT

Product: HAD family hydrolase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 254; Mature: 253

Protein sequence:

>254_residues
MTSPSIQNIKAVLFDLSGVLYIGTDALPGAVETVHRLKQQGFILRFVTNTASQPSEMILRQLNQLGFDVEEAELYTAPKA
AKQYLLHHQLRPYCLIHTLLKAEFKDIDQTNPNCVLLGDAQDDLTYQSLNKAFNLVEKGYPLIGIGKNKYYKDAEGFKLD
AGTFIHALEWASDTHAIITGKPDKTFFDEVVASTGVPATQCLMIGDDVRGDVEGAINAGLQAALVRTGKFKPSDEKILPD
TAWILDGIQKLSLS

Sequences:

>Translated_254_residues
MTSPSIQNIKAVLFDLSGVLYIGTDALPGAVETVHRLKQQGFILRFVTNTASQPSEMILRQLNQLGFDVEEAELYTAPKA
AKQYLLHHQLRPYCLIHTLLKAEFKDIDQTNPNCVLLGDAQDDLTYQSLNKAFNLVEKGYPLIGIGKNKYYKDAEGFKLD
AGTFIHALEWASDTHAIITGKPDKTFFDEVVASTGVPATQCLMIGDDVRGDVEGAINAGLQAALVRTGKFKPSDEKILPD
TAWILDGIQKLSLS
>Mature_253_residues
TSPSIQNIKAVLFDLSGVLYIGTDALPGAVETVHRLKQQGFILRFVTNTASQPSEMILRQLNQLGFDVEEAELYTAPKAA
KQYLLHHQLRPYCLIHTLLKAEFKDIDQTNPNCVLLGDAQDDLTYQSLNKAFNLVEKGYPLIGIGKNKYYKDAEGFKLDA
GTFIHALEWASDTHAIITGKPDKTFFDEVVASTGVPATQCLMIGDDVRGDVEGAINAGLQAALVRTGKFKPSDEKILPDT
AWILDGIQKLSLS

Specific function: Unknown

COG id: COG0647

COG function: function code G; Predicted sugar phosphatases of the HAD superfamily

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 nudix hydrolase domain [H]

Homologues:

Organism=Homo sapiens, GI14149777, Length=236, Percent_Identity=44.9152542372881, Blast_Score=203, Evalue=1e-52,
Organism=Homo sapiens, GI269847098, Length=236, Percent_Identity=44.9152542372881, Blast_Score=197, Evalue=7e-51,
Organism=Homo sapiens, GI269847104, Length=201, Percent_Identity=41.7910447761194, Blast_Score=153, Evalue=2e-37,
Organism=Escherichia coli, GI1786890, Length=254, Percent_Identity=25.5905511811024, Blast_Score=87, Evalue=1e-18,
Organism=Caenorhabditis elegans, GI17562356, Length=233, Percent_Identity=36.480686695279, Blast_Score=156, Evalue=8e-39,
Organism=Caenorhabditis elegans, GI17557870, Length=241, Percent_Identity=30.7053941908714, Blast_Score=139, Evalue=1e-33,
Organism=Drosophila melanogaster, GI19920940, Length=240, Percent_Identity=35.8333333333333, Blast_Score=159, Evalue=1e-39,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005834
- InterPro:   IPR023214
- InterPro:   IPR006357
- InterPro:   IPR023215
- InterPro:   IPR020476
- InterPro:   IPR020084
- InterPro:   IPR000086
- InterPro:   IPR015797 [H]

Pfam domain/function: PF00702 Hydrolase; PF00293 NUDIX [H]

EC number: NA

Molecular weight: Translated: 27925; Mature: 27794

Theoretical pI: Translated: 5.33; Mature: 5.33

Prosite motif: PS50801 STAS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
0.8 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTSPSIQNIKAVLFDLSGVLYIGTDALPGAVETVHRLKQQGFILRFVTNTASQPSEMILR
CCCCCHHHHHHHHHHHCCEEEECCCCCCHHHHHHHHHHHCCEEEEEECCCCCCHHHHHHH
QLNQLGFDVEEAELYTAPKAAKQYLLHHQLRPYCLIHTLLKAEFKDIDQTNPNCVLLGDA
HHHHHCCCCHHHHHHCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCCCCEEEEECC
QDDLTYQSLNKAFNLVEKGYPLIGIGKNKYYKDAEGFKLDAGTFIHALEWASDTHAIITG
CHHHHHHHHHHHHHHHHCCCCEEEECCCCCCCCCCCCEECCHHHHHHHHHCCCCCEEEEC
KPDKTFFDEVVASTGVPATQCLMIGDDVRGDVEGAINAGLQAALVRTGKFKPSDEKILPD
CCCHHHHHHHHHHCCCCHHEEEEECCCCCCCHHHHHHCCHHHHHHHCCCCCCCCCCCCCH
TAWILDGIQKLSLS
HHHHHHHHHHHCCC
>Mature Secondary Structure 
TSPSIQNIKAVLFDLSGVLYIGTDALPGAVETVHRLKQQGFILRFVTNTASQPSEMILR
CCCCHHHHHHHHHHHCCEEEECCCCCCHHHHHHHHHHHCCEEEEEECCCCCCHHHHHHH
QLNQLGFDVEEAELYTAPKAAKQYLLHHQLRPYCLIHTLLKAEFKDIDQTNPNCVLLGDA
HHHHHCCCCHHHHHHCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCCCCEEEEECC
QDDLTYQSLNKAFNLVEKGYPLIGIGKNKYYKDAEGFKLDAGTFIHALEWASDTHAIITG
CHHHHHHHHHHHHHHHHCCCCEEEECCCCCCCCCCCCEECCHHHHHHHHHCCCCCEEEEC
KPDKTFFDEVVASTGVPATQCLMIGDDVRGDVEGAINAGLQAALVRTGKFKPSDEKILPD
CCCHHHHHHHHHHCCCCHHEEEEECCCCCCCHHHHHHCCHHHHHHHCCCCCCCCCCCCCH
TAWILDGIQKLSLS
HHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8631946 [H]