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The map label for this gene is pitA [C]

Identifier: 78358819

GI number: 78358819

Start: 3724493

End: 3725728

Strand: Reverse

Name: pitA [C]

Synonym: Dde_3781

Alternate gene names: 78358819

Gene position: 3725728-3724493 (Counterclockwise)

Preceding gene: 78358822

Following gene: 78358818

Centisome position: 99.88

GC content: 54.21

Gene sequence:

>1236_bases
ATGGATATATACACTGTTTTTCTTGTTCTCGCCGTCGGCGCCGGCTTTATGATGGCATTCAATCTGGGGGCCAACGATGT
GGCCAACTCCATGGCATCATCGGTCGGTTCCAAAGCCATCACCGTCAAACAGGCGGTAATGATTGCCGGTGTGCTGAACT
TTGTGGGCGCCGTATTTCTGGGTGCTCATGTAACTAAAACTATCAGCAAGGGTATCATCAACGCGGATATGATAACAGAC
CCGCGGGTGATGATGGTAGGCATGTTCGCCGCATTGCTTTCTGCTGCCTTGTGGGTGCTGGTGGCCACGCTTACGTCGCT
GCCGGTTTCTTCCACGCACTCCATCGTGGGGTCGATTCTCGGATTCGGCATTGTTGCCGGAGGGCCCGAAGTCGTCAACT
GGGGCAGTATGGGCTTTGTGGTGCTTTCATGGATCATTTCGCCGCTTTTTGGCGCAGGCATTGCTTTTTTTGTATTTTCC
CATATACGGCGGTTTATTCTGTACCGAACCAAGATAATAGAAAAAGCGAGATTCTGGGCCCCGTTCTGGATAGCGCTTAC
CGCCGATCTTGTGGTGCTTTCGTTTTTTTATAAAACGCCGGTGGGCAAGAGTCTTAACCTGCACTGGTCTGTGGCGCTGG
GGCTGACCGCCGTGCTGACGGTGGCTGTGTGGACTGGTTTCCGGGTGCTGTTCACACGCACGCTGCCCAAAGATGCCGAC
GGACCCGAAGCAGTGGAAGACATGTTCCGCCGTCTGCAGGTGGGTACGGCCTGTTATGTGGCGGTGTCGCAGGGCGCCAA
CGATGTGGCCAACGCCATAGGCCCTGTGGCTGCCATATACCTGATAGCGCGCGAACGCACGCTGCTGGCTTCTGCGGAGG
TGCCCCTGTGGCTTCTGGTCATCGGCGGGCTGGGCATTGCGTTGGGCATTGCCGTGCTGGGGCACAAGGTTATGGCCACC
GTGGGTGAAAAAATAACCAAACTGACCAATACCCGTGGTTTTTCTGTGGAATTCGGAGCGGCCACAACAGTTCTCATGGC
ATCAAATCTGGGAATGCCGGTTTCTTCCACACACGCCGCTGTGGGGTCCATAGTGGGCGTGGGGCTGGCCAGAGGCTTTG
GTGCCGTTGATTTTAGAGTACTTTACAAAATAGTGCTTTATTGGGTACTTACAGTACCTATTGCCGCTATAACCAGTATC
GTCATTTTCCAGCTTCTCAGATGGTCGTTTTTGTAG

Upstream 100 bases:

>100_bases
AACACAGGCATCCGGCTGCTCCCCGTTTACCTGTGCACCTTCCGGTCACCGCTATCAGGGTAATTCAGGGCATCGCTCAT
CCCTTAAACGGACAGGTTAC

Downstream 100 bases:

>100_bases
GACCCTGAAGGCTGTTACCGGAGGCTTCATATATGAACATTCGAATCCCCCTCTTCGGGCTTGTACGCGACGAACGCTCG
CCCATGACAGGACTTGTCGA

Product: sodium/phosphate symporter

Products: Proton [Cytoplasm]; phosphate [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 411; Mature: 411

Protein sequence:

>411_residues
MDIYTVFLVLAVGAGFMMAFNLGANDVANSMASSVGSKAITVKQAVMIAGVLNFVGAVFLGAHVTKTISKGIINADMITD
PRVMMVGMFAALLSAALWVLVATLTSLPVSSTHSIVGSILGFGIVAGGPEVVNWGSMGFVVLSWIISPLFGAGIAFFVFS
HIRRFILYRTKIIEKARFWAPFWIALTADLVVLSFFYKTPVGKSLNLHWSVALGLTAVLTVAVWTGFRVLFTRTLPKDAD
GPEAVEDMFRRLQVGTACYVAVSQGANDVANAIGPVAAIYLIARERTLLASAEVPLWLLVIGGLGIALGIAVLGHKVMAT
VGEKITKLTNTRGFSVEFGAATTVLMASNLGMPVSSTHAAVGSIVGVGLARGFGAVDFRVLYKIVLYWVLTVPIAAITSI
VIFQLLRWSFL

Sequences:

>Translated_411_residues
MDIYTVFLVLAVGAGFMMAFNLGANDVANSMASSVGSKAITVKQAVMIAGVLNFVGAVFLGAHVTKTISKGIINADMITD
PRVMMVGMFAALLSAALWVLVATLTSLPVSSTHSIVGSILGFGIVAGGPEVVNWGSMGFVVLSWIISPLFGAGIAFFVFS
HIRRFILYRTKIIEKARFWAPFWIALTADLVVLSFFYKTPVGKSLNLHWSVALGLTAVLTVAVWTGFRVLFTRTLPKDAD
GPEAVEDMFRRLQVGTACYVAVSQGANDVANAIGPVAAIYLIARERTLLASAEVPLWLLVIGGLGIALGIAVLGHKVMAT
VGEKITKLTNTRGFSVEFGAATTVLMASNLGMPVSSTHAAVGSIVGVGLARGFGAVDFRVLYKIVLYWVLTVPIAAITSI
VIFQLLRWSFL
>Mature_411_residues
MDIYTVFLVLAVGAGFMMAFNLGANDVANSMASSVGSKAITVKQAVMIAGVLNFVGAVFLGAHVTKTISKGIINADMITD
PRVMMVGMFAALLSAALWVLVATLTSLPVSSTHSIVGSILGFGIVAGGPEVVNWGSMGFVVLSWIISPLFGAGIAFFVFS
HIRRFILYRTKIIEKARFWAPFWIALTADLVVLSFFYKTPVGKSLNLHWSVALGLTAVLTVAVWTGFRVLFTRTLPKDAD
GPEAVEDMFRRLQVGTACYVAVSQGANDVANAIGPVAAIYLIARERTLLASAEVPLWLLVIGGLGIALGIAVLGHKVMAT
VGEKITKLTNTRGFSVEFGAATTVLMASNLGMPVSSTHAAVGSIVGVGLARGFGAVDFRVLYKIVLYWVLTVPIAAITSI
VIFQLLRWSFL

Specific function: Potential transporter for phosphate [H]

COG id: COG0306

COG function: function code P; Phosphate/sulphate permeases

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the inorganic phosphate transporter (PiT) (TC 2.A.20) family [H]

Homologues:

Organism=Homo sapiens, GI31543630, Length=174, Percent_Identity=43.1034482758621, Blast_Score=151, Evalue=9e-37,
Organism=Homo sapiens, GI5803173, Length=164, Percent_Identity=43.9024390243902, Blast_Score=144, Evalue=1e-34,
Organism=Caenorhabditis elegans, GI17539280, Length=170, Percent_Identity=47.0588235294118, Blast_Score=151, Evalue=6e-37,
Organism=Caenorhabditis elegans, GI25146401, Length=185, Percent_Identity=38.3783783783784, Blast_Score=142, Evalue=3e-34,
Organism=Caenorhabditis elegans, GI17557328, Length=483, Percent_Identity=25.879917184265, Blast_Score=140, Evalue=9e-34,
Organism=Caenorhabditis elegans, GI71981576, Length=186, Percent_Identity=37.6344086021505, Blast_Score=137, Evalue=1e-32,
Organism=Caenorhabditis elegans, GI32566716, Length=191, Percent_Identity=34.0314136125654, Blast_Score=120, Evalue=9e-28,
Organism=Caenorhabditis elegans, GI17536725, Length=174, Percent_Identity=35.0574712643678, Blast_Score=105, Evalue=3e-23,
Organism=Saccharomyces cerevisiae, GI6319773, Length=159, Percent_Identity=39.622641509434, Blast_Score=120, Evalue=3e-28,
Organism=Drosophila melanogaster, GI21356511, Length=187, Percent_Identity=42.7807486631016, Blast_Score=136, Evalue=2e-32,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001204 [H]

Pfam domain/function: PF01384 PHO4 [H]

EC number: NA

Molecular weight: Translated: 43622; Mature: 43622

Theoretical pI: Translated: 10.35; Mature: 10.35

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDIYTVFLVLAVGAGFMMAFNLGANDVANSMASSVGSKAITVKQAVMIAGVLNFVGAVFL
CHHHHHHHHHHHCCHHHEEEECCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHH
GAHVTKTISKGIINADMITDPRVMMVGMFAALLSAALWVLVATLTSLPVSSTHSIVGSIL
HHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHH
GFGIVAGGPEVVNWGSMGFVVLSWIISPLFGAGIAFFVFSHIRRFILYRTKIIEKARFWA
HHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
PFWIALTADLVVLSFFYKTPVGKSLNLHWSVALGLTAVLTVAVWTGFRVLFTRTLPKDAD
HHHHHHHHHHHHHHHHHHCCCCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHEECCCCCCC
GPEAVEDMFRRLQVGTACYVAVSQGANDVANAIGPVAAIYLIARERTLLASAEVPLWLLV
CHHHHHHHHHHHHHCHHHEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHH
IGGLGIALGIAVLGHKVMATVGEKITKLTNTRGFSVEFGAATTVLMASNLGMPVSSTHAA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEECCHHHHHHHHHCCCCCCCHHHHH
VGSIVGVGLARGFGAVDFRVLYKIVLYWVLTVPIAAITSIVIFQLLRWSFL
HHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MDIYTVFLVLAVGAGFMMAFNLGANDVANSMASSVGSKAITVKQAVMIAGVLNFVGAVFL
CHHHHHHHHHHHCCHHHEEEECCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHH
GAHVTKTISKGIINADMITDPRVMMVGMFAALLSAALWVLVATLTSLPVSSTHSIVGSIL
HHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHH
GFGIVAGGPEVVNWGSMGFVVLSWIISPLFGAGIAFFVFSHIRRFILYRTKIIEKARFWA
HHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
PFWIALTADLVVLSFFYKTPVGKSLNLHWSVALGLTAVLTVAVWTGFRVLFTRTLPKDAD
HHHHHHHHHHHHHHHHHHCCCCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHEECCCCCCC
GPEAVEDMFRRLQVGTACYVAVSQGANDVANAIGPVAAIYLIARERTLLASAEVPLWLLV
CHHHHHHHHHHHHHCHHHEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHH
IGGLGIALGIAVLGHKVMATVGEKITKLTNTRGFSVEFGAATTVLMASNLGMPVSSTHAA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEECCHHHHHHHHHCCCCCCCHHHHH
VGSIVGVGLARGFGAVDFRVLYKIVLYWVLTVPIAAITSIVIFQLLRWSFL
HHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Proton [Periplasm]; phosphate [Periplasm] [C]

Specific reaction: Proton [Periplasm] + phosphate [Periplasm] = Proton [Cytoplasm] + phosphate [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 12622808 [H]