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The map label for this gene is mdtA [H]

Identifier: 78358667

GI number: 78358667

Start: 3592267

End: 3593352

Strand: Direct

Name: mdtA [H]

Synonym: Dde_3628

Alternate gene names: 78358667

Gene position: 3592267-3593352 (Clockwise)

Preceding gene: 78358665

Following gene: 78358668

Centisome position: 96.3

GC content: 62.06

Gene sequence:

>1086_bases
ATGCACAAGCCTGCACCCATGATTCGTATCCCGTCTCTTATAGCGGTTTTACTCGTTTTCTTGCAAGTCTATAACGCCGC
TGCCGCCGCAGACGGAGAAAAAAGACAGGCCCCCCCGCCGGCACAGGTGGTCACGGCCCATGCGCGCTCCGGCGAAGCAA
GCCCCCATGCGGAATACATCGGCACTGTGGAATTTCCCGAAGTGTCCGCCGTGGCATCTGAAGTGGGCGGACGGGTTGCC
TCTGTAAGCATAGAGGAAGGCAGAAAGGTGCGGCGCGATGAACAGCTGGCCGTCATCGACAGCCAGCTGCTGTCAAAAGA
CTATCAGTCGGCCGTGGCGCAGCACCGCACCGTGCTTGCCGATCTGGAAAACGCCGCGCTGGAACTGGAGAGACTGGAAA
CCCTGCGCGAATCGCGTTCCATCTCGGAACAGCAGTATGATGTGGGCAGGTTCAAGGAAGCAGGGCTGCGCCGTAAAGCT
GAATCGCTGAAGGCGGAAGCCGAACGGCTGGCAATCCAGATAGGAAAATGCGTCATACGTGCTCCGTTTGACGGCATTGT
ACTGGAAAAGCTGAGCAGCCCCGGCGAATGGGTTTCGCCGGGAACCGTTGTGGCCAGACTGGCCAGAACCGATGCCATGG
ACGTACGGGTTTCCGTACCGGAAGCGGTGCTGCCGTTTGTCACCGAGGGACGCAAGGTGGTTGCGCGCACGGGCCAGCAG
GAATACGAAGGACACGTCACGGCTGTCATTCCGCTGGGCGATGTGGCCACAAGAACCTTCCCCGTCAAGGTACGGCTCAA
ACGCACCGACGGGCTGGCGCAGGGCATGCAGGCCCGCGTGGGGCTGCCCACGGATGAGGCGCGTCCCGCCGTGCTGGTGC
CCCGCGATGCCGTTATCCGCTCCGCCGGACGCATGGTTGTCTGGACAGTGCAGAACGGCACCGCCGTGCCTGTGGATGTG
GTGGTCAACGCATGGCTGGGGCTGGATGCCGCCGTGGCCGGCAAAGGTCTTGTGCAGGGCTCTGAAGTGGTGATCAAAGG
CAACGAACGGCTGCGTCCGGGCCAACCTGTCACGGCTGCCCGCTGA

Upstream 100 bases:

>100_bases
GACAAATTACAGGCAAAGTAGGTCCTCTGCCCCGTGTGTGCTTGGCTCGCGAAGCGCATTAGGCTATCAATGGCACAGCA
AACGCCAACACGGAGTCGCC

Downstream 100 bases:

>100_bases
GTGTCTTTGCAGAACGCATTGTTTACGCTATGGTGCGCCTGACCCGGTACAGGCAGGCCCTCCGGGGCCGTGATATTTTT
TTGCCCACGTATCAACCCCG

Product: secretion protein HlyD

Products: NA

Alternate protein names: Multidrug transporter mdtA [H]

Number of amino acids: Translated: 361; Mature: 361

Protein sequence:

>361_residues
MHKPAPMIRIPSLIAVLLVFLQVYNAAAAADGEKRQAPPPAQVVTAHARSGEASPHAEYIGTVEFPEVSAVASEVGGRVA
SVSIEEGRKVRRDEQLAVIDSQLLSKDYQSAVAQHRTVLADLENAALELERLETLRESRSISEQQYDVGRFKEAGLRRKA
ESLKAEAERLAIQIGKCVIRAPFDGIVLEKLSSPGEWVSPGTVVARLARTDAMDVRVSVPEAVLPFVTEGRKVVARTGQQ
EYEGHVTAVIPLGDVATRTFPVKVRLKRTDGLAQGMQARVGLPTDEARPAVLVPRDAVIRSAGRMVVWTVQNGTAVPVDV
VVNAWLGLDAAVAGKGLVQGSEVVIKGNERLRPGQPVTAAR

Sequences:

>Translated_361_residues
MHKPAPMIRIPSLIAVLLVFLQVYNAAAAADGEKRQAPPPAQVVTAHARSGEASPHAEYIGTVEFPEVSAVASEVGGRVA
SVSIEEGRKVRRDEQLAVIDSQLLSKDYQSAVAQHRTVLADLENAALELERLETLRESRSISEQQYDVGRFKEAGLRRKA
ESLKAEAERLAIQIGKCVIRAPFDGIVLEKLSSPGEWVSPGTVVARLARTDAMDVRVSVPEAVLPFVTEGRKVVARTGQQ
EYEGHVTAVIPLGDVATRTFPVKVRLKRTDGLAQGMQARVGLPTDEARPAVLVPRDAVIRSAGRMVVWTVQNGTAVPVDV
VVNAWLGLDAAVAGKGLVQGSEVVIKGNERLRPGQPVTAAR
>Mature_361_residues
MHKPAPMIRIPSLIAVLLVFLQVYNAAAAADGEKRQAPPPAQVVTAHARSGEASPHAEYIGTVEFPEVSAVASEVGGRVA
SVSIEEGRKVRRDEQLAVIDSQLLSKDYQSAVAQHRTVLADLENAALELERLETLRESRSISEQQYDVGRFKEAGLRRKA
ESLKAEAERLAIQIGKCVIRAPFDGIVLEKLSSPGEWVSPGTVVARLARTDAMDVRVSVPEAVLPFVTEGRKVVARTGQQ
EYEGHVTAVIPLGDVATRTFPVKVRLKRTDGLAQGMQARVGLPTDEARPAVLVPRDAVIRSAGRMVVWTVQNGTAVPVDV
VVNAWLGLDAAVAGKGLVQGSEVVIKGNERLRPGQPVTAAR

Specific function: Unknown

COG id: COG0845

COG function: function code M; Membrane-fusion protein

Gene ontology:

Cell location: Cell inner membrane; Peripheral membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family [H]

Homologues:

Organism=Escherichia coli, GI87082036, Length=319, Percent_Identity=25.705329153605, Blast_Score=63, Evalue=3e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR022824
- InterPro:   IPR006143 [H]

Pfam domain/function: PF00529 HlyD [H]

EC number: NA

Molecular weight: Translated: 38777; Mature: 38777

Theoretical pI: Translated: 9.36; Mature: 9.36

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
1.7 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
1.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MHKPAPMIRIPSLIAVLLVFLQVYNAAAAADGEKRQAPPPAQVVTAHARSGEASPHAEYI
CCCCCCCEEHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHEEEECCCCCCCCCHHHC
GTVEFPEVSAVASEVGGRVASVSIEEGRKVRRDEQLAVIDSQLLSKDYQSAVAQHRTVLA
CCCCCCHHHHHHHHHCCEEEEEEHHHCHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
DLENAALELERLETLRESRSISEQQYDVGRFKEAGLRRKAESLKAEAERLAIQIGKCVIR
HHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEE
APFDGIVLEKLSSPGEWVSPGTVVARLARTDAMDVRVSVPEAVLPFVTEGRKVVARTGQQ
CCCCHHHHHHHCCCCCCCCCHHHHHHHHHCCCCEEEEECCHHHHHHHHCCCHHHHHCCCH
EYEGHVTAVIPLGDVATRTFPVKVRLKRTDGLAQGMQARVGLPTDEARPAVLVPRDAVIR
HHCCCEEEEEECCCHHCCEEEEEEEEECCCCHHHCCHHHCCCCCCCCCCEEECCHHHHHH
SAGRMVVWTVQNGTAVPVDVVVNAWLGLDAAVAGKGLVQGSEVVIKGNERLRPGQPVTAA
CCCCEEEEEECCCCCCHHHHHHHHHHCCCHHHHCCCCCCCCEEEEECCCCCCCCCCCCCC
R
C
>Mature Secondary Structure
MHKPAPMIRIPSLIAVLLVFLQVYNAAAAADGEKRQAPPPAQVVTAHARSGEASPHAEYI
CCCCCCCEEHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHEEEECCCCCCCCCHHHC
GTVEFPEVSAVASEVGGRVASVSIEEGRKVRRDEQLAVIDSQLLSKDYQSAVAQHRTVLA
CCCCCCHHHHHHHHHCCEEEEEEHHHCHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
DLENAALELERLETLRESRSISEQQYDVGRFKEAGLRRKAESLKAEAERLAIQIGKCVIR
HHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEE
APFDGIVLEKLSSPGEWVSPGTVVARLARTDAMDVRVSVPEAVLPFVTEGRKVVARTGQQ
CCCCHHHHHHHCCCCCCCCCHHHHHHHHHCCCCEEEEECCHHHHHHHHCCCHHHHHCCCH
EYEGHVTAVIPLGDVATRTFPVKVRLKRTDGLAQGMQARVGLPTDEARPAVLVPRDAVIR
HHCCCEEEEEECCCHHCCEEEEEEEEECCCCHHHCCHHHCCCCCCCCCCEEECCHHHHHH
SAGRMVVWTVQNGTAVPVDVVVNAWLGLDAAVAGKGLVQGSEVVIKGNERLRPGQPVTAA
CCCCEEEEEECCCCCCHHHHHHHHHHCCCHHHHCCCCCCCCEEEEECCCCCCCCCCCCCC
R
C

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA