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The map label for this gene is trpS [H]

Identifier: 78358646

GI number: 78358646

Start: 3567678

End: 3568667

Strand: Reverse

Name: trpS [H]

Synonym: Dde_3607

Alternate gene names: 78358646

Gene position: 3568667-3567678 (Counterclockwise)

Preceding gene: 78358647

Following gene: 78358645

Centisome position: 95.67

GC content: 56.97

Gene sequence:

>990_bases
ATGAGCAATAATCGCACTGTTTCGGGCATGCGTCCCACCGGCGCACTGCACCTTGGCCACTACTTCGGCGTGCTGAAAAA
CTGGGTGGAAATGCAGCACGAAATGGAAGCATTTTTCTTTGTGGCCGACTGGCACGCCCTGACAAGCGACTTCGCCGATC
CTACCCGCATCAAGGGCTTTGTGCCCGAACTGGTGATGGACTGGGTAGCCTCCGGTCTTGATCCTCAGAAGTGTACCATT
TTTCAGCAGTCGCAGGTCAAACAGCACGCCGAGCTGCACCTGCTGCTTTCCATGATAACTCCGCTGGGCTGGCTGGAACG
CTGTCCCACGTACAAGGAACAGCAGCAGCAGATAACCAACAAAGATCTGGGTAACTACGGTTTTCTGGGGTACCCCGTGC
TGATGGCTTCCGATATTCTCATCTACCGGCCTCAGTGGGTTCCGGTGGGACAGGACCAGCTGCCGCACCTTGAAATGACC
CGAGAAATCTGCCGCCGCTTCAACCATTTCTACGGTGAATATCTTGTGGAACCTCAGGCCCGCCTGACCCCCGCCGCCAA
ATGTCCCGGCCTTGACGGGCGCAAGATGTCCAAAAGCTACGGCAACGCCATTCATCTGGGTGAGCCCATGGAAGACATCA
TACCCAAGGTGCGTGGCATGAAGACGGATGAAAACCGTCTGCGGCGCAATGATCCGGGCAATCCTGAGGTGTGCAACCTG
TTCCCCTACCACGTGCTGATGACCGCGGAAGACAGACAGGCCGAAATACGTCAGGGCTGCACTTCTGCCGGGCTGGGCTG
TGTGGACTGCAAAAAAATTCTTCTTGAAAGCCTTGAGCGTTTTCTGACACCCATCCACGAGCGCCGCAGAGAGCTGGAAA
GCCGTCCCGACACGGTGTGGGACATTCTGCGCGACGGCAACGCCCGCGCCCGTGAAGAGGCCGAGCGCACCATGGAAGGC
GTGCGTCAGCGTCTAAGCTTTGATTTTTAA

Upstream 100 bases:

>100_bases
CTGGGCCGCGTGCTGTGGCCGCTTGTGGATGGTTCCGCCCGTGTGGTCACTTCCATGCTCGGGCTTGCCATCTGATCATC
TTATCCGGAGGAACATTGAA

Downstream 100 bases:

>100_bases
CAACCAACCATAATGACCGCGGGCGCACCATGTGCGCCCGTCGTTTTTCAGGAGACGCCATGACCGCACCGCATACGGAA
ACAGACAGCACTCAGCAGTT

Product: tryptophanyl-tRNA synthetase

Products: NA

Alternate protein names: Tryptophan--tRNA ligase; TrpRS [H]

Number of amino acids: Translated: 329; Mature: 328

Protein sequence:

>329_residues
MSNNRTVSGMRPTGALHLGHYFGVLKNWVEMQHEMEAFFFVADWHALTSDFADPTRIKGFVPELVMDWVASGLDPQKCTI
FQQSQVKQHAELHLLLSMITPLGWLERCPTYKEQQQQITNKDLGNYGFLGYPVLMASDILIYRPQWVPVGQDQLPHLEMT
REICRRFNHFYGEYLVEPQARLTPAAKCPGLDGRKMSKSYGNAIHLGEPMEDIIPKVRGMKTDENRLRRNDPGNPEVCNL
FPYHVLMTAEDRQAEIRQGCTSAGLGCVDCKKILLESLERFLTPIHERRRELESRPDTVWDILRDGNARAREEAERTMEG
VRQRLSFDF

Sequences:

>Translated_329_residues
MSNNRTVSGMRPTGALHLGHYFGVLKNWVEMQHEMEAFFFVADWHALTSDFADPTRIKGFVPELVMDWVASGLDPQKCTI
FQQSQVKQHAELHLLLSMITPLGWLERCPTYKEQQQQITNKDLGNYGFLGYPVLMASDILIYRPQWVPVGQDQLPHLEMT
REICRRFNHFYGEYLVEPQARLTPAAKCPGLDGRKMSKSYGNAIHLGEPMEDIIPKVRGMKTDENRLRRNDPGNPEVCNL
FPYHVLMTAEDRQAEIRQGCTSAGLGCVDCKKILLESLERFLTPIHERRRELESRPDTVWDILRDGNARAREEAERTMEG
VRQRLSFDF
>Mature_328_residues
SNNRTVSGMRPTGALHLGHYFGVLKNWVEMQHEMEAFFFVADWHALTSDFADPTRIKGFVPELVMDWVASGLDPQKCTIF
QQSQVKQHAELHLLLSMITPLGWLERCPTYKEQQQQITNKDLGNYGFLGYPVLMASDILIYRPQWVPVGQDQLPHLEMTR
EICRRFNHFYGEYLVEPQARLTPAAKCPGLDGRKMSKSYGNAIHLGEPMEDIIPKVRGMKTDENRLRRNDPGNPEVCNLF
PYHVLMTAEDRQAEIRQGCTSAGLGCVDCKKILLESLERFLTPIHERRRELESRPDTVWDILRDGNARAREEAERTMEGV
RQRLSFDF

Specific function: Unknown

COG id: COG0180

COG function: function code J; Tryptophanyl-tRNA synthetase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I aminoacyl-tRNA synthetase family [H]

Homologues:

Organism=Homo sapiens, GI7710154, Length=333, Percent_Identity=31.5315315315315, Blast_Score=172, Evalue=3e-43,
Organism=Homo sapiens, GI41352700, Length=183, Percent_Identity=36.6120218579235, Blast_Score=135, Evalue=7e-32,
Organism=Escherichia coli, GI1789786, Length=336, Percent_Identity=30.6547619047619, Blast_Score=156, Evalue=1e-39,
Organism=Caenorhabditis elegans, GI71982800, Length=332, Percent_Identity=28.0120481927711, Blast_Score=133, Evalue=1e-31,
Organism=Caenorhabditis elegans, GI71982793, Length=332, Percent_Identity=28.0120481927711, Blast_Score=132, Evalue=4e-31,
Organism=Saccharomyces cerevisiae, GI6320474, Length=350, Percent_Identity=31.1428571428571, Blast_Score=145, Evalue=7e-36,
Organism=Drosophila melanogaster, GI24666151, Length=332, Percent_Identity=29.8192771084337, Blast_Score=152, Evalue=4e-37,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001412
- InterPro:   IPR002305
- InterPro:   IPR014729
- InterPro:   IPR002306 [H]

Pfam domain/function: PF00579 tRNA-synt_1b [H]

EC number: =6.1.1.2 [H]

Molecular weight: Translated: 37950; Mature: 37819

Theoretical pI: Translated: 6.73; Mature: 6.73

Prosite motif: PS00178 AA_TRNA_LIGASE_I

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.4 %Cys     (Translated Protein)
4.0 %Met     (Translated Protein)
6.4 %Cys+Met (Translated Protein)
2.4 %Cys     (Mature Protein)
3.7 %Met     (Mature Protein)
6.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSNNRTVSGMRPTGALHLGHYFGVLKNWVEMQHEMEAFFFVADWHALTSDFADPTRIKGF
CCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHH
VPELVMDWVASGLDPQKCTIFQQSQVKQHAELHLLLSMITPLGWLERCPTYKEQQQQITN
HHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHH
KDLGNYGFLGYPVLMASDILIYRPQWVPVGQDQLPHLEMTREICRRFNHFYGEYLVEPQA
CCCCCCCCHHHHHHHHCCEEEECCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCHH
RLTPAAKCPGLDGRKMSKSYGNAIHLGEPMEDIIPKVRGMKTDENRLRRNDPGNPEVCNL
HCCCHHCCCCCCCHHHHHHHCCEEECCCCHHHHHHHHCCCCCCHHHHHCCCCCCCCCEEE
FPYHVLMTAEDRQAEIRQGCTSAGLGCVDCKKILLESLERFLTPIHERRRELESRPDTVW
CCEEEEEECCHHHHHHHHCHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHH
DILRDGNARAREEAERTMEGVRQRLSFDF
HHHHCCCCHHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure 
SNNRTVSGMRPTGALHLGHYFGVLKNWVEMQHEMEAFFFVADWHALTSDFADPTRIKGF
CCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHH
VPELVMDWVASGLDPQKCTIFQQSQVKQHAELHLLLSMITPLGWLERCPTYKEQQQQITN
HHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHH
KDLGNYGFLGYPVLMASDILIYRPQWVPVGQDQLPHLEMTREICRRFNHFYGEYLVEPQA
CCCCCCCCHHHHHHHHCCEEEECCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCHH
RLTPAAKCPGLDGRKMSKSYGNAIHLGEPMEDIIPKVRGMKTDENRLRRNDPGNPEVCNL
HCCCHHCCCCCCCHHHHHHHCCEEECCCCHHHHHHHHCCCCCCHHHHHCCCCCCCCCEEE
FPYHVLMTAEDRQAEIRQGCTSAGLGCVDCKKILLESLERFLTPIHERRRELESRPDTVW
CCEEEEEECCHHHHHHHHCHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHH
DILRDGNARAREEAERTMEGVRQRLSFDF
HHHHCCCCHHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10360571 [H]