Click here to switch to the map view.

The map label for this gene is yacO [H]

Identifier: 78358620

GI number: 78358620

Start: 3541092

End: 3541853

Strand: Direct

Name: yacO [H]

Synonym: Dde_3581

Alternate gene names: 78358620

Gene position: 3541092-3541853 (Clockwise)

Preceding gene: 78358618

Following gene: 78358631

Centisome position: 94.93

GC content: 58.27

Gene sequence:

>762_bases
ATGCTCATCATGAAACCAGAAACTACCGACAGCACCATACTTCCGGGCATAAAGCCCGTCCTTGACCAGCTGCGCCAGTC
GCCGGACCGTGTTGATTCCGTGACCATACGCAAAGGGCGCAAAAACGCCGACACCGACGCCATAGTGACGCTGTGCCGCA
GACACGGCATACGCTTTACATTTGTACAGGATACGGCGCTGGATAAATTATTTTCCGGCAACCATCAGGGGGTGGTGGCC
CGCGTGTTCAATGCGGGATACGTAGAAGTGGAAGACGTGCTTGAAGCGGCGCTTGCAAGTCCTCTCAAGCTTGTTCTTGC
TCTTGATCAGGTGCAGGACCCCGGCAATGCCGGTACGCTGGCGCGCACGCTGTACGCGCTGGGCGGCGGAGGCATAATCA
TGCCCAAGCACAATGCATCTGCACTGGGCAGTGCGGCTGTCAAAGCCAGTGCCGGCGCCCTTGCGCGGTTGCCCGTGGCC
AGAGCCACCAACCTTTCAAGAGCGCTCGAAACCGCTGCAGATCAGGGTTTTTCCATTTATGCAGCCCGCTTTGACGATGG
TTCTGTCAATGCGTTCACCGCACGGCTCGATACACCTGCCGTGCTGGTGCTGGGCAACGAAGACAAAGGGGTACGGCCCG
GCGTTGCAAAACGCTGCACAGCTTCCATCCATATTCCCATGCAGCGCGAATTCGACTCGCTGAACGTGGCACAGGCGGGA
GCCATGCTCATGGGCTGCTTCTATGCCCGGCTGCAATCATAG

Upstream 100 bases:

>100_bases
GTGAAGTAGCCTCCTGTTACCCTAAACGCCAAGGGGAGGCAATGCGGCAGTTCCGCCTTCAACCCTCAGACCACGCCCGC
GCAGCTCTCTGCTGTGCGGC

Downstream 100 bases:

>100_bases
TCACCGGCACCCAAAGCTTTGCAACGCCGCCCCGCAGCCCGCGGGGCGGCGTTCTGTTTTTTTCCTGCCGCGGGTGCGGT
CAACGCACATAGTTGGGTAT

Product: RNA methyltransferase TrmH, group 3

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 253; Mature: 253

Protein sequence:

>253_residues
MLIMKPETTDSTILPGIKPVLDQLRQSPDRVDSVTIRKGRKNADTDAIVTLCRRHGIRFTFVQDTALDKLFSGNHQGVVA
RVFNAGYVEVEDVLEAALASPLKLVLALDQVQDPGNAGTLARTLYALGGGGIIMPKHNASALGSAAVKASAGALARLPVA
RATNLSRALETAADQGFSIYAARFDDGSVNAFTARLDTPAVLVLGNEDKGVRPGVAKRCTASIHIPMQREFDSLNVAQAG
AMLMGCFYARLQS

Sequences:

>Translated_253_residues
MLIMKPETTDSTILPGIKPVLDQLRQSPDRVDSVTIRKGRKNADTDAIVTLCRRHGIRFTFVQDTALDKLFSGNHQGVVA
RVFNAGYVEVEDVLEAALASPLKLVLALDQVQDPGNAGTLARTLYALGGGGIIMPKHNASALGSAAVKASAGALARLPVA
RATNLSRALETAADQGFSIYAARFDDGSVNAFTARLDTPAVLVLGNEDKGVRPGVAKRCTASIHIPMQREFDSLNVAQAG
AMLMGCFYARLQS
>Mature_253_residues
MLIMKPETTDSTILPGIKPVLDQLRQSPDRVDSVTIRKGRKNADTDAIVTLCRRHGIRFTFVQDTALDKLFSGNHQGVVA
RVFNAGYVEVEDVLEAALASPLKLVLALDQVQDPGNAGTLARTLYALGGGGIIMPKHNASALGSAAVKASAGALARLPVA
RATNLSRALETAADQGFSIYAARFDDGSVNAFTARLDTPAVLVLGNEDKGVRPGVAKRCTASIHIPMQREFDSLNVAQAG
AMLMGCFYARLQS

Specific function: Unknown

COG id: COG0566

COG function: function code J; rRNA methylases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the RNA methyltransferase TrmH family [H]

Homologues:

Organism=Homo sapiens, GI40068479, Length=185, Percent_Identity=29.1891891891892, Blast_Score=66, Evalue=3e-11,
Organism=Escherichia coli, GI1790623, Length=241, Percent_Identity=29.045643153527, Blast_Score=94, Evalue=1e-20,
Organism=Caenorhabditis elegans, GI17555908, Length=262, Percent_Identity=26.3358778625954, Blast_Score=69, Evalue=3e-12,
Organism=Saccharomyces cerevisiae, GI6324775, Length=172, Percent_Identity=29.6511627906977, Blast_Score=67, Evalue=4e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004441
- InterPro:   IPR001537
- InterPro:   IPR013123 [H]

Pfam domain/function: PF00588 SpoU_methylase; PF08032 SpoU_sub_bind [H]

EC number: 2.1.1.- [C]

Molecular weight: Translated: 26845; Mature: 26845

Theoretical pI: Translated: 9.20; Mature: 9.20

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLIMKPETTDSTILPGIKPVLDQLRQSPDRVDSVTIRKGRKNADTDAIVTLCRRHGIRFT
CEEECCCCCCCCCCCCHHHHHHHHHCCCCHHCEEEEECCCCCCCHHHHHHHHHHCCCEEE
FVQDTALDKLFSGNHQGVVARVFNAGYVEVEDVLEAALASPLKLVLALDQVQDPGNAGTL
EECHHHHHHHHCCCCCCEEEEECCCCCEEHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHH
ARTLYALGGGGIIMPKHNASALGSAAVKASAGALARLPVARATNLSRALETAADQGFSIY
HHHHHHHCCCCEEEECCCCHHHHHHHHHHCCCCHHHCCHHHHHHHHHHHHHHHCCCCEEE
AARFDDGSVNAFTARLDTPAVLVLGNEDKGVRPGVAKRCTASIHIPMQREFDSLNVAQAG
EEEECCCCCEEEEEECCCCEEEEECCCCCCCCCCHHHHCEEEEECCHHHCCCCCCHHHHH
AMLMGCFYARLQS
HHHHHHHHHHHCC
>Mature Secondary Structure
MLIMKPETTDSTILPGIKPVLDQLRQSPDRVDSVTIRKGRKNADTDAIVTLCRRHGIRFT
CEEECCCCCCCCCCCCHHHHHHHHHCCCCHHCEEEEECCCCCCCHHHHHHHHHHCCCEEE
FVQDTALDKLFSGNHQGVVARVFNAGYVEVEDVLEAALASPLKLVLALDQVQDPGNAGTL
EECHHHHHHHHCCCCCCEEEEECCCCCEEHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHH
ARTLYALGGGGIIMPKHNASALGSAAVKASAGALARLPVARATNLSRALETAADQGFSIY
HHHHHHHCCCCEEEECCCCHHHHHHHHHHCCCCHHHCCHHHHHHHHHHHHHHHCCCCEEE
AARFDDGSVNAFTARLDTPAVLVLGNEDKGVRPGVAKRCTASIHIPMQREFDSLNVAQAG
EEEECCCCCEEEEEECCCCEEEEECCCCCCCCCCHHHHCEEEEECCHHHCCCCCCHHHHH
AMLMGCFYARLQS
HHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7584024; 9384377; 7510287; 3145906 [H]