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The map label for this gene is yneB [C]

Identifier: 78358541

GI number: 78358541

Start: 3461275

End: 3462075

Strand: Direct

Name: yneB [C]

Synonym: Dde_3502

Alternate gene names: 78358541

Gene position: 3461275-3462075 (Clockwise)

Preceding gene: 78358540

Following gene: 78358542

Centisome position: 92.79

GC content: 62.3

Gene sequence:

>801_bases
ATGATCGGAGCCATCCGCAAACTCGAACGATTTTTCATGACCCCCAGCGGCAGGGCCGTGGTGCTGCCGCTGGACCACGG
TGCCGGTGAAGGCATGCTGCACGGGCTGGACAATATACCCGGTCTGCTTGCGGACATAGGCGACCGTCCGGTGCAGGGCG
TGGTGCTGAACAAGGGCACGGCACGCGCCTACGCAAATGAAATCCCCACGGCCACGCAGCTTGTGGTGCAGCTTTCCGCC
GGAACCCGGCACGGGCTGCCCGCGTGGAACAAATCGCTGGTCTGCTCCATTCCCGAAGCGCTGCGCCTGGGGGCCGACGC
CGTGGCCGTACAGGTGAACATCGGCAACGAACAGGAAGACCGGATGCTTACGGATCTGGGCATGGCCACGGAAGAAGCGC
ACCAGCACGGCCTGCCGGTGATGGCCGTCATCGTGGCGCGGGGCGGCAACATAGTGCAGGAGCTTGACCCTTCGCTCATC
GCCCATTGTGTCAGGCTGGGCGGCGAGCTGGGGCCCGACATGGTCTGTGTTCCCTATTCCGGTCATATGGACAGTTTTTC
ACGGGCCGTTGATGCCTGTCCCGTGCCCGTACTGGTGGCGGGCGGCCCTTCTATGGGTGACTTTGAAAATTTTATCAGGC
ACATGGAAGAAGCGCTTGAATGCGGCGCCGCCGGTGTAAGCATCGGGCGCAATATTTTTCAGCAGGACGACCCCATGGCG
GCGCTGGACAGACTGCTGACAGTGGTACACAGCCAGCGGGACGACAAAACACCGCAGGAAAACGACGTGCGGAACGGGTA
A

Upstream 100 bases:

>100_bases
GCAGCGGCCACAGGACACATCTCACGCCGGAAGCGCTGGCCTTCTGTCCGTTCCTCGGCTGCAATGCCCGCGGCGTTCAA
TGCCATACACAGGAGACACC

Downstream 100 bases:

>100_bases
TCATGTTCAAGGTTGTTGTCATTTTGTTTGTCGCGGTCTGGGTGCTCAGCTTTTTTCTGAGCAGCCGGCGCAAGGTCATC
CGCGACACAAACCACCTGCT

Product: fructose-bisphosphate aldolase

Products: NA

Alternate protein names: ADH synthase; ADHS; Transaldolase-like ADHS [H]

Number of amino acids: Translated: 266; Mature: 266

Protein sequence:

>266_residues
MIGAIRKLERFFMTPSGRAVVLPLDHGAGEGMLHGLDNIPGLLADIGDRPVQGVVLNKGTARAYANEIPTATQLVVQLSA
GTRHGLPAWNKSLVCSIPEALRLGADAVAVQVNIGNEQEDRMLTDLGMATEEAHQHGLPVMAVIVARGGNIVQELDPSLI
AHCVRLGGELGPDMVCVPYSGHMDSFSRAVDACPVPVLVAGGPSMGDFENFIRHMEEALECGAAGVSIGRNIFQQDDPMA
ALDRLLTVVHSQRDDKTPQENDVRNG

Sequences:

>Translated_266_residues
MIGAIRKLERFFMTPSGRAVVLPLDHGAGEGMLHGLDNIPGLLADIGDRPVQGVVLNKGTARAYANEIPTATQLVVQLSA
GTRHGLPAWNKSLVCSIPEALRLGADAVAVQVNIGNEQEDRMLTDLGMATEEAHQHGLPVMAVIVARGGNIVQELDPSLI
AHCVRLGGELGPDMVCVPYSGHMDSFSRAVDACPVPVLVAGGPSMGDFENFIRHMEEALECGAAGVSIGRNIFQQDDPMA
ALDRLLTVVHSQRDDKTPQENDVRNG
>Mature_266_residues
MIGAIRKLERFFMTPSGRAVVLPLDHGAGEGMLHGLDNIPGLLADIGDRPVQGVVLNKGTARAYANEIPTATQLVVQLSA
GTRHGLPAWNKSLVCSIPEALRLGADAVAVQVNIGNEQEDRMLTDLGMATEEAHQHGLPVMAVIVARGGNIVQELDPSLI
AHCVRLGGELGPDMVCVPYSGHMDSFSRAVDACPVPVLVAGGPSMGDFENFIRHMEEALECGAAGVSIGRNIFQQDDPMA
ALDRLLTVVHSQRDDKTPQENDVRNG

Specific function: Catalyzes a transaldol reaction between 6-deoxy-5- ketofructose 1-phosphate (DKFP) and L-aspartate semialdehyde (ASA) with an elimination of hydroxypyruvaldehyde phosphate to yield 2- amino-3,7-dideoxy-D-threo-hept-6-ulosonic acid (ADH). Plays a key role

COG id: COG1830

COG function: function code G; DhnA-type fructose-1,6-bisphosphate aldolase and related enzymes

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the deoC/fbaB aldolase family. ADHS subfamily [H]

Homologues:

Organism=Escherichia coli, GI1787796, Length=250, Percent_Identity=31.2, Blast_Score=107, Evalue=1e-24,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013785
- InterPro:   IPR010210
- InterPro:   IPR002915 [H]

Pfam domain/function: PF01791 DeoC [H]

EC number: 4.2.1.- [C]

Molecular weight: Translated: 28278; Mature: 28278

Theoretical pI: Translated: 4.84; Mature: 4.84

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
4.1 %Met     (Translated Protein)
6.0 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
4.1 %Met     (Mature Protein)
6.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIGAIRKLERFFMTPSGRAVVLPLDHGAGEGMLHGLDNIPGLLADIGDRPVQGVVLNKGT
CCHHHHHHHHHHCCCCCCEEEEECCCCCCCCHHHCCCCCCHHHHHCCCCCCCEEEECCCC
ARAYANEIPTATQLVVQLSAGTRHGLPAWNKSLVCSIPEALRLGADAVAVQVNIGNEQED
HHHHHHHCCHHHHHHEEECCCCCCCCCCCCCCEEEECHHHHHCCCCEEEEEEECCCCHHH
RMLTDLGMATEEAHQHGLPVMAVIVARGGNIVQELDPSLIAHCVRLGGELGPDMVCVPYS
HHHHHHCCHHHHHHHCCCCEEEHEECCCCCHHHHCCHHHHHHHHHHCCCCCCCEEEECCC
GHMDSFSRAVDACPVPVLVAGGPSMGDFENFIRHMEEALECGAAGVSIGRNIFQQDDPMA
CCHHHHHHHHHCCCCCEEEECCCCCCHHHHHHHHHHHHHHHCHHHHHHHHHHHHCCCHHH
ALDRLLTVVHSQRDDKTPQENDVRNG
HHHHHHHHHHHCCCCCCCCCCCCCCC
>Mature Secondary Structure
MIGAIRKLERFFMTPSGRAVVLPLDHGAGEGMLHGLDNIPGLLADIGDRPVQGVVLNKGT
CCHHHHHHHHHHCCCCCCEEEEECCCCCCCCHHHCCCCCCHHHHHCCCCCCCEEEECCCC
ARAYANEIPTATQLVVQLSAGTRHGLPAWNKSLVCSIPEALRLGADAVAVQVNIGNEQED
HHHHHHHCCHHHHHHEEECCCCCCCCCCCCCCEEEECHHHHHCCCCEEEEEEECCCCHHH
RMLTDLGMATEEAHQHGLPVMAVIVARGGNIVQELDPSLIAHCVRLGGELGPDMVCVPYS
HHHHHHCCHHHHHHHCCCCEEEHEECCCCCHHHHCCHHHHHHHHHHCCCCCCCEEEECCC
GHMDSFSRAVDACPVPVLVAGGPSMGDFENFIRHMEEALECGAAGVSIGRNIFQQDDPMA
CCHHHHHHHHHCCCCCEEEECCCCCCHHHHHHHHHHHHHHHCHHHHHHHHHHHHCCCHHH
ALDRLLTVVHSQRDDKTPQENDVRNG
HHHHHHHHHHHCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]