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The map label for this gene is buk

Identifier: 78358168

GI number: 78358168

Start: 3121011

End: 3122129

Strand: Reverse

Name: buk

Synonym: Dde_3128

Alternate gene names: 78358168

Gene position: 3122129-3121011 (Counterclockwise)

Preceding gene: 78358169

Following gene: 78358167

Centisome position: 83.7

GC content: 63.36

Gene sequence:

>1119_bases
ATGAGTCTGATCCTGACCATTAATCCCGGATCGACAAGCACCAAGATAGCGGTGTTTGCAGCGGAAGAGGAACTTTTTGA
ACGTACGGTGGAGCATCCCCATGATGCCTTTTCCGGTCTGGCCGGTGTATACGGGCAGCTGGAAGCGCGGCGGCATGCCG
TTCAGACCATGCTGTCCCGGGCCGGTTATGCCGATGCCCGTTTTGATATTGTGGTGGGACGCGGCGGTTTGCTGGCCCCC
ATGCACGGTGGTGCATGGCGTGTGAACCAGACCATGCTTGATATTCTGGAATCCGCTGCGCACGGCGAGCATCCTTGTAA
TCTCGGCGCACCGCTGGCTCTGGCGTTTGCCCGCAGCCACGGGGCGCACCGGAATGTACAGGCCATCATAGTGGATCCTG
TGGTTACGGATGAACTGGACCCCGTGGCCCGTATAGGCGGATTGCCTGAACTGCCGCGCCGTAGCGTGTTTCACGCGCTT
TCACAGCGCGCGGCGGCACGCAGGGCAGCGGCACAGCTGGGCATACGTTATGAGGATGGCCGTTTTCTGGTCGGGCATTT
CGGGGGTGGCATTTCTGTAGGGGCGCACCGCCACGGCAGAGTGGTGGACGTGAACAACGCGCTGGAAGGAGAAGGGCCTT
TTTCACCGGAGCGGACGGGCGGCCTGCCTGTCATGCCCGCTCTGGAGCTGGTACGCAGAGGCGTGTACTCGTTTGAGCGC
ATGCGCAGTATTGTGCAGCGCGAAGGAGGCATGTGGGCGCATCTGGGCACCAACGACCTGCGCGAGGTACAGCGCAGGAT
GGACGCCGGTGATACCGCAGCGGCGCAGATTTTCGACGCGCTGGCTTACAACAGCGCCAAGGCTCTGTGCGCGCTGTTAC
CGGCACTGACCGGCGCGGGGCAGGACGTCCCGTCGGCCCCGCCGGTGGATGCGGTGGTGCTTACAGGCGGAATGGCGCGT
TCCGGGCGGTTCATGCAGGCTGTTTCGGACAGGCTGCGCTATCTCGGACCGGTCATAGTGCTGCCCCGTCTGGAAGAGAT
GCAGGCACTGGCCATGGGCGGTCTGCGGGTGCTGCGGGGTGAGGAGACCCCCGCGGAATACGGCGGCGGCATGTCCTGA

Upstream 100 bases:

>100_bases
GCAGGATTCCTCTTATCGTCCCTTCCCGCGGCGACAGCGACCGCAGCAAACTGTATGCACTGGCTCTGGCAGCCTACATG
ACCCGTAAGGAATGCACCGG

Downstream 100 bases:

>100_bases
GACTGCGCGGCTTTTTTCAGGGTACAGCAGGCGGGGGCCGCAAGGCTGCCCGCCTGTATACTTGACGTGCGCGGCGTATA
GTAGTTTAGTGCTGGCCTTC

Product: butyrate kinase

Products: NA

Alternate protein names: BK; Branched-chain carboxylic acid kinase

Number of amino acids: Translated: 372; Mature: 371

Protein sequence:

>372_residues
MSLILTINPGSTSTKIAVFAAEEELFERTVEHPHDAFSGLAGVYGQLEARRHAVQTMLSRAGYADARFDIVVGRGGLLAP
MHGGAWRVNQTMLDILESAAHGEHPCNLGAPLALAFARSHGAHRNVQAIIVDPVVTDELDPVARIGGLPELPRRSVFHAL
SQRAAARRAAAQLGIRYEDGRFLVGHFGGGISVGAHRHGRVVDVNNALEGEGPFSPERTGGLPVMPALELVRRGVYSFER
MRSIVQREGGMWAHLGTNDLREVQRRMDAGDTAAAQIFDALAYNSAKALCALLPALTGAGQDVPSAPPVDAVVLTGGMAR
SGRFMQAVSDRLRYLGPVIVLPRLEEMQALAMGGLRVLRGEETPAEYGGGMS

Sequences:

>Translated_372_residues
MSLILTINPGSTSTKIAVFAAEEELFERTVEHPHDAFSGLAGVYGQLEARRHAVQTMLSRAGYADARFDIVVGRGGLLAP
MHGGAWRVNQTMLDILESAAHGEHPCNLGAPLALAFARSHGAHRNVQAIIVDPVVTDELDPVARIGGLPELPRRSVFHAL
SQRAAARRAAAQLGIRYEDGRFLVGHFGGGISVGAHRHGRVVDVNNALEGEGPFSPERTGGLPVMPALELVRRGVYSFER
MRSIVQREGGMWAHLGTNDLREVQRRMDAGDTAAAQIFDALAYNSAKALCALLPALTGAGQDVPSAPPVDAVVLTGGMAR
SGRFMQAVSDRLRYLGPVIVLPRLEEMQALAMGGLRVLRGEETPAEYGGGMS
>Mature_371_residues
SLILTINPGSTSTKIAVFAAEEELFERTVEHPHDAFSGLAGVYGQLEARRHAVQTMLSRAGYADARFDIVVGRGGLLAPM
HGGAWRVNQTMLDILESAAHGEHPCNLGAPLALAFARSHGAHRNVQAIIVDPVVTDELDPVARIGGLPELPRRSVFHALS
QRAAARRAAAQLGIRYEDGRFLVGHFGGGISVGAHRHGRVVDVNNALEGEGPFSPERTGGLPVMPALELVRRGVYSFERM
RSIVQREGGMWAHLGTNDLREVQRRMDAGDTAAAQIFDALAYNSAKALCALLPALTGAGQDVPSAPPVDAVVLTGGMARS
GRFMQAVSDRLRYLGPVIVLPRLEEMQALAMGGLRVLRGEETPAEYGGGMS

Specific function: Anaerobic degradation of L-threonine to propionate. [C]

COG id: COG3426

COG function: function code C; Butyrate kinase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the acetokinase family

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): BUK_DESDG (Q30WM4)

Other databases:

- EMBL:   CP000112
- RefSeq:   YP_389617.1
- ProteinModelPortal:   Q30WM4
- SMR:   Q30WM4
- STRING:   Q30WM4
- GeneID:   3758102
- GenomeReviews:   CP000112_GR
- KEGG:   dde:Dde_3128
- NMPDR:   fig|207559.3.peg.3600
- eggNOG:   COG3426
- HOGENOM:   HBG449785
- OMA:   RSIFHAL
- ProtClustDB:   PRK03011
- BioCyc:   DDES207559:DDE_3128-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00542
- InterPro:   IPR000890
- InterPro:   IPR011245
- PANTHER:   PTHR21060
- PANTHER:   PTHR21060:SF3
- PIRSF:   PIRSF036458
- PRINTS:   PR00471
- TIGRFAMs:   TIGR02707

Pfam domain/function: PF00871 Acetate_kinase

EC number: =2.7.2.7

Molecular weight: Translated: 39711; Mature: 39580

Theoretical pI: Translated: 7.21; Mature: 7.21

Prosite motif: PS01075 ACETATE_KINASE_1; PS01076 ACETATE_KINASE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSLILTINPGSTSTKIAVFAAEEELFERTVEHPHDAFSGLAGVYGQLEARRHAVQTMLSR
CEEEEEECCCCCCCEEEEEECHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
AGYADARFDIVVGRGGLLAPMHGGAWRVNQTMLDILESAAHGEHPCNLGAPLALAFARSH
CCCCCCEEEEEECCCCEEECCCCCCEEHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHC
GAHRNVQAIIVDPVVTDELDPVARIGGLPELPRRSVFHALSQRAAARRAAAQLGIRYEDG
CCCCCCEEEEECCHHCCCCCHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCEECCC
RFLVGHFGGGISVGAHRHGRVVDVNNALEGEGPFSPERTGGLPVMPALELVRRGVYSFER
CEEEEECCCCEEECCCCCCCEEECCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHH
MRSIVQREGGMWAHLGTNDLREVQRRMDAGDTAAAQIFDALAYNSAKALCALLPALTGAG
HHHHHHHCCCEEEECCCHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
QDVPSAPPVDAVVLTGGMARSGRFMQAVSDRLRYLGPVIVLPRLEEMQALAMGGLRVLRG
CCCCCCCCCCEEEEECCCCCCCHHHHHHHHHHHHHCCEEECCCHHHHHHHHHCCCCEECC
EETPAEYGGGMS
CCCCHHCCCCCC
>Mature Secondary Structure 
SLILTINPGSTSTKIAVFAAEEELFERTVEHPHDAFSGLAGVYGQLEARRHAVQTMLSR
EEEEEECCCCCCCEEEEEECHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
AGYADARFDIVVGRGGLLAPMHGGAWRVNQTMLDILESAAHGEHPCNLGAPLALAFARSH
CCCCCCEEEEEECCCCEEECCCCCCEEHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHC
GAHRNVQAIIVDPVVTDELDPVARIGGLPELPRRSVFHALSQRAAARRAAAQLGIRYEDG
CCCCCCEEEEECCHHCCCCCHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCEECCC
RFLVGHFGGGISVGAHRHGRVVDVNNALEGEGPFSPERTGGLPVMPALELVRRGVYSFER
CEEEEECCCCEEECCCCCCCEEECCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHH
MRSIVQREGGMWAHLGTNDLREVQRRMDAGDTAAAQIFDALAYNSAKALCALLPALTGAG
HHHHHHHCCCEEEECCCHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
QDVPSAPPVDAVVLTGGMARSGRFMQAVSDRLRYLGPVIVLPRLEEMQALAMGGLRVLRG
CCCCCCCCCCEEEEECCCCCCCHHHHHHHHHHHHHCCEEECCCHHHHHHHHHCCCCEECC
EETPAEYGGGMS
CCCCHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA