Click here to switch to the map view.

The map label for this gene is sdaA [H]

Identifier: 78358074

GI number: 78358074

Start: 3021708

End: 3022940

Strand: Direct

Name: sdaA [H]

Synonym: Dde_3034

Alternate gene names: 78358074

Gene position: 3021708-3022940 (Clockwise)

Preceding gene: 78358073

Following gene: 78358077

Centisome position: 81.01

GC content: 60.18

Gene sequence:

>1233_bases
ATGGACTCTCTCAAGGAACTCTACAAGGTGGGCAACGGCCCTTCCAGCAGCCACACCATGGGCCCGCAAAAGGCAGCCAC
AGAGTTTCTGCGGCGCACCCCGCAGGCTGCGCATTACCGTGTCACGCTGCTCGGCAGCCTTGCCGCCACGGGCAAAGGCC
ACCTGACAGACTGGATCATCAAAAAAACACTGGGTGAAGAACGCACGACCATTGTCTGGAAACCAGAAGAGGTACGTCCC
TTCCACACCAACGGCATGGTTTTCGAAGCGCTGGACGCACAGGGGAACGTGCCGGAAGACCCCGCCTCCACCTGGGAAGT
GTACAGCGTGGGCGGCGGCACCATAGCCGAACCGGATTCGCTGACACGCGGTGCCGGCAATTTTTACTCGCTTACCACTC
TCACGGCCATCATGGGTCACTGCCGTGCGGACAACATAGAGCTGTGGGAGTATGTCGAATCTCAGGAAGGCCCGGGCCTG
TGGCCTTTTCTGCAGGACATCTGGCAGGCCATGCAGGACTCCATAGAACGCGGACTGGGCAAAACCGGCCTGCTGCCGGG
CGACCTGCGCTACCCGCGCAAAGCCAACGCGTTTTACAAAAAAGCCCGCATCCAGTCCGGCAGGCTGCGTTCCACCGGTA
TGACATTCGCCTATGCACTGGCAGTGTCGGAAGAAAACGCCTCCGGCGGGCTGGTGGTTACCGCGCCCACCTGCGGCTCG
GCAGGTCTGGTGCCCGCCGTGCTGCGTTCGCTTAAAGAAGATTACAGCCTTGCCGACACAGAAATACTGAAAGCTCTTGC
CGTGGGCGGACTGGTCGGCAACCTTGTAAAGGAAAACGCCTCCATATCGGGTGCCGAAGTGGGCTGTCAGGGCGAAGTGG
GTACAGCGTGCGCCATGGCCGCGGCCATGACCGCCTATCTGTTCGGCGGTACCCATATGCAGATAGACTACGCCGCGGAA
ATGGCGCTGGAACACCATCTGGGCATGACCTGTGACCCCGTGGGCGGGTATGTACAGGTGCCCTGTATAGAACGCAACGC
GGTTTCGGCCATCAGAGCCATCAACGCAGCGGAATACACGCTGTTCACCGACGGAAACCACCGTATCAGTTTTGATCAGG
TGGTGCAGACCATGGGCGAAACCGGCAGAGACCTGAAGTGCGGTTACAGAGAAACTTCACTGGCAGGGCTGGCCAAACAC
GCCTGCCTGACCAACTGCGGCAGCGGGTGCTGA

Upstream 100 bases:

>100_bases
CCGCGGCGCTGAGCGCCGCAGACAGTGCACGCCGCCGCGGCCCGCGCGGCACGGCGCCGCCGGACAGCCTTTTTTATATA
CTGCACACAACGGAGTACAT

Downstream 100 bases:

>100_bases
AACTGCCCGCAGCAGATATATGACAAACGGCCCGTGCCTTGTGCGCGGGCCGTTCTGCGTGCGCCGTCTGCTAACGTAAT
GAGCGGTGCATAAACCGCAG

Product: L-serine ammonia-lyase

Products: NA

Alternate protein names: SDH; L-serine deaminase; L-SD [H]

Number of amino acids: Translated: 410; Mature: 410

Protein sequence:

>410_residues
MDSLKELYKVGNGPSSSHTMGPQKAATEFLRRTPQAAHYRVTLLGSLAATGKGHLTDWIIKKTLGEERTTIVWKPEEVRP
FHTNGMVFEALDAQGNVPEDPASTWEVYSVGGGTIAEPDSLTRGAGNFYSLTTLTAIMGHCRADNIELWEYVESQEGPGL
WPFLQDIWQAMQDSIERGLGKTGLLPGDLRYPRKANAFYKKARIQSGRLRSTGMTFAYALAVSEENASGGLVVTAPTCGS
AGLVPAVLRSLKEDYSLADTEILKALAVGGLVGNLVKENASISGAEVGCQGEVGTACAMAAAMTAYLFGGTHMQIDYAAE
MALEHHLGMTCDPVGGYVQVPCIERNAVSAIRAINAAEYTLFTDGNHRISFDQVVQTMGETGRDLKCGYRETSLAGLAKH
ACLTNCGSGC

Sequences:

>Translated_410_residues
MDSLKELYKVGNGPSSSHTMGPQKAATEFLRRTPQAAHYRVTLLGSLAATGKGHLTDWIIKKTLGEERTTIVWKPEEVRP
FHTNGMVFEALDAQGNVPEDPASTWEVYSVGGGTIAEPDSLTRGAGNFYSLTTLTAIMGHCRADNIELWEYVESQEGPGL
WPFLQDIWQAMQDSIERGLGKTGLLPGDLRYPRKANAFYKKARIQSGRLRSTGMTFAYALAVSEENASGGLVVTAPTCGS
AGLVPAVLRSLKEDYSLADTEILKALAVGGLVGNLVKENASISGAEVGCQGEVGTACAMAAAMTAYLFGGTHMQIDYAAE
MALEHHLGMTCDPVGGYVQVPCIERNAVSAIRAINAAEYTLFTDGNHRISFDQVVQTMGETGRDLKCGYRETSLAGLAKH
ACLTNCGSGC
>Mature_410_residues
MDSLKELYKVGNGPSSSHTMGPQKAATEFLRRTPQAAHYRVTLLGSLAATGKGHLTDWIIKKTLGEERTTIVWKPEEVRP
FHTNGMVFEALDAQGNVPEDPASTWEVYSVGGGTIAEPDSLTRGAGNFYSLTTLTAIMGHCRADNIELWEYVESQEGPGL
WPFLQDIWQAMQDSIERGLGKTGLLPGDLRYPRKANAFYKKARIQSGRLRSTGMTFAYALAVSEENASGGLVVTAPTCGS
AGLVPAVLRSLKEDYSLADTEILKALAVGGLVGNLVKENASISGAEVGCQGEVGTACAMAAAMTAYLFGGTHMQIDYAAE
MALEHHLGMTCDPVGGYVQVPCIERNAVSAIRAINAAEYTLFTDGNHRISFDQVVQTMGETGRDLKCGYRETSLAGLAKH
ACLTNCGSGC

Specific function: Deaminates Also Threonine, Particularly When It Is Present In High Concentration. [C]

COG id: COG1760

COG function: function code E; L-serine deaminase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the iron-sulfur dependent L-serine dehydratase family [H]

Homologues:

Organism=Escherichia coli, GI1788116, Length=453, Percent_Identity=38.8520971302428, Blast_Score=277, Evalue=8e-76,
Organism=Escherichia coli, GI48994925, Length=461, Percent_Identity=39.4793926247288, Blast_Score=271, Evalue=8e-74,
Organism=Escherichia coli, GI1789161, Length=449, Percent_Identity=38.0846325167038, Blast_Score=262, Evalue=3e-71,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004644
- InterPro:   IPR005130
- InterPro:   IPR005131 [H]

Pfam domain/function: PF03313 SDH_alpha; PF03315 SDH_beta [H]

EC number: =4.3.1.17 [H]

Molecular weight: Translated: 43855; Mature: 43855

Theoretical pI: Translated: 5.81; Mature: 5.81

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.4 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
5.4 %Cys+Met (Translated Protein)
2.4 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
5.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDSLKELYKVGNGPSSSHTMGPQKAATEFLRRTPQAAHYRVTLLGSLAATGKGHLTDWII
CCHHHHHHHCCCCCCCCCCCCHHHHHHHHHHCCCCCCEEEEEEEEHHHCCCCCCHHHHHH
KKTLGEERTTIVWKPEEVRPFHTNGMVFEALDAQGNVPEDPASTWEVYSVGGGTIAEPDS
HHHCCCCCCEEEECCCCCCCCCCCCEEEEEECCCCCCCCCCCCCEEEEECCCCCCCCCCH
LTRGAGNFYSLTTLTAIMGHCRADNIELWEYVESQEGPGLWPFLQDIWQAMQDSIERGLG
HCCCCCCHHHHHHHHHHHHHCCCCCCHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHCCC
KTGLLPGDLRYPRKANAFYKKARIQSGRLRSTGMTFAYALAVSEENASGGLVVTAPTCGS
CCCCCCCCCCCCCHHHHHHHHHHHCCCCCCCCCCEEEEEEEEECCCCCCCEEEECCCCCC
AGLVPAVLRSLKEDYSLADTEILKALAVGGLVGNLVKENASISGAEVGCQGEVGTACAMA
CCCHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHH
AAMTAYLFGGTHMQIDYAAEMALEHHLGMTCDPVGGYVQVPCIERNAVSAIRAINAAEYT
HHHHHHHHCCCEEEEHHHHHHHHHHHCCCCCCCCCCEEEECEECHHHHHHHHHHCCCEEE
LFTDGNHRISFDQVVQTMGETGRDLKCGYRETSLAGLAKHACLTNCGSGC
EEECCCCEECHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCC
>Mature Secondary Structure
MDSLKELYKVGNGPSSSHTMGPQKAATEFLRRTPQAAHYRVTLLGSLAATGKGHLTDWII
CCHHHHHHHCCCCCCCCCCCCHHHHHHHHHHCCCCCCEEEEEEEEHHHCCCCCCHHHHHH
KKTLGEERTTIVWKPEEVRPFHTNGMVFEALDAQGNVPEDPASTWEVYSVGGGTIAEPDS
HHHCCCCCCEEEECCCCCCCCCCCCEEEEEECCCCCCCCCCCCCEEEEECCCCCCCCCCH
LTRGAGNFYSLTTLTAIMGHCRADNIELWEYVESQEGPGLWPFLQDIWQAMQDSIERGLG
HCCCCCCHHHHHHHHHHHHHCCCCCCHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHCCC
KTGLLPGDLRYPRKANAFYKKARIQSGRLRSTGMTFAYALAVSEENASGGLVVTAPTCGS
CCCCCCCCCCCCCHHHHHHHHHHHCCCCCCCCCCEEEEEEEEECCCCCCCEEEECCCCCC
AGLVPAVLRSLKEDYSLADTEILKALAVGGLVGNLVKENASISGAEVGCQGEVGTACAMA
CCCHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHH
AAMTAYLFGGTHMQIDYAAEMALEHHLGMTCDPVGGYVQVPCIERNAVSAIRAINAAEYT
HHHHHHHHCCCEEEEHHHHHHHHHHHCCCCCCCCCCEEEECEECHHHHHHHHHHCCCEEE
LFTDGNHRISFDQVVQTMGETGRDLKCGYRETSLAGLAKHACLTNCGSGC
EEECCCCEECHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]