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The map label for this gene is rpfC [H]

Identifier: 78357969

GI number: 78357969

Start: 2908579

End: 2910399

Strand: Reverse

Name: rpfC [H]

Synonym: Dde_2929

Alternate gene names: 78357969

Gene position: 2910399-2908579 (Counterclockwise)

Preceding gene: 78357976

Following gene: 78357966

Centisome position: 78.02

GC content: 56.23

Gene sequence:

>1821_bases
ATGCCGCGAGGCATGGCTTGCCCCTGCATACATGAAGAGCAAAGACTTTTGAAGAACAAAGCGTCGGGTCTGTCAGGAGA
ATTCCGGCCGGCGAGTTGCCCAGTTGCGTACGTATGGTGTAGAACCCTGCTGTCAGATTTCAAACAGAAGGCGGAAACAC
ACATGGCATCACGTCAGGAGATGACTGAAAGCGGAGCGATAGCGGCCTGTGGCGAAGGCGCTGATTCCCGTTCGCTGGAG
GCGGAGATTCTGCGCCTGCGCCAGCGTGAAAAGGAACTGCTGCATGAGCGGCAGATGCTTAAGGATATTCTGAAAGCCAT
TCCCGACATGCTGACGGTGCATGACCGAGACGGCAATGTCATGTTCAGCAATTGCAAGCCCAACGAGGACTGCTGGCAGC
ATCATGGCGGAACCAAACACGGTTTGCGCTGTTATCAGTGCCATTTCCACGGCGACCGCAACTGTGAAGACTGTTATATT
CCCGATGTGTTCGATTCCGGCGAACAGCGTGTTGTGGAAATGTACAACCCCGACATGAAGAGTTTTCGCTCCATTACTGT
GTTTCCCGTGCGTGACGGGCAGGGTGATGTGACCATGGTGGCCGAATATGTGCGCGATGTGACCGCCACCCGTAATCTGG
AGCGCGAACTGCGCGTGGCAAAAGAGGCCGCCGAGGCAGCCGACAGGGCGAAAAGTGAATTTCTGGCTTCCATGAGCCAT
GAGATACGCACCCCCATGAACGGCGTGCTGGGCATGCTTGATCTGGCCATGACAACCAGTCTGGATGAAGAGCAGCGGGA
GTACCTCGAAGCAGTGCAGAATTCTGCGGAAGCTCTTCTTTCGCTGATAAACGATATTCTGGATTTTTCTAAGATCGAAG
CCGGAATGGTGGAACTGGATCAGCAGGTCTTCCGTCTCAGCAAGCGTCTTTCTTCACTGCATACCATGTTTGTGCACCGT
GCCGCTGAACGGAACCTTGAGTTCGCCATCAACATTTCCCCCGACGTGCCGGACGGATTGTCCGGTGACCCGCTGCGTCT
GCGGCAGATTGTGGTTAACCTGCTTGATAATGCTTTCAAGTTCACCGATCAGGGGCAGGTGGTGCTGAGTGTGGAAGTGC
TGGAGCGCGGAGCGGAGAATGTTCTGCTGCAGTTCAGCGTGCAGGATACCGGTCCCGGCATTCTGGAGAGACATCAGGAG
CGTATTTTCGACAGTTTTGCCCAGGCCGATGCGTCGTTTACCCGCAGACATCAGGGGTCCGGGCTCGGGCTGGCCATCTG
CAAACGCCTGACCGGTCTTATGGGCGGCGACATCAAGGTGCGCAGCACGCCGGGAGAAGGCAGTACTTTTGTGTTCTCCG
CACGGTTCGGCGTAGCCGTGCTGGACGAGGAACCCGTACGGGTGCGCAGCCGCACAGCAGAACCTGCACCGGTGCGCGGG
CGGATTCTTGTGGCGGAAGATCACCCCATGAATCTTATGTTTATCGAAAAATTTCTTAAAAAGCAGGGGTACGAATCTGT
CAGCGTGACTGATGGCAGCGAGGTGGTTCCCGCACTCACGCGGTCACGGTTTGATCTGGTGCTGATGGACATTGCCATGC
CCGCCATGGACGGCATGGAGGCGACCCGCGCCGTGCGTGCTGCCACGGGTATGAAGACCCCCAGTGATGTGCCTATTATT
GCCATGACGGCGCACGCCATGAAAGGTGACCGAGAGCAGTTTCTTGAAGCCGGAATGGACGATTACATAGGTAAGCCCAT
CAACTCCGACAATCTGCGCAGTATGATTATCCGGCACCTGCAGGCCCGGCGCAAAAGCTGA

Upstream 100 bases:

>100_bases
TCTGCTGTCATGAAAAACCCGTGGACGGATACATGTCAGCCCCGGAAATTCTGTCCGGATGAACTCCATCAACCACTCCT
ATGCTGGCGGGAAGTATGGC

Downstream 100 bases:

>100_bases
TACGGCAACTGCAGGGCAGTGTGACAACAGGGTTGCACTTTTGCCGCCACGGCTGTATATGACGACTCCTGCCGTATGGC
AGTTCATATCGCGGAAGGGT

Product: histidine kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 606; Mature: 605

Protein sequence:

>606_residues
MPRGMACPCIHEEQRLLKNKASGLSGEFRPASCPVAYVWCRTLLSDFKQKAETHMASRQEMTESGAIAACGEGADSRSLE
AEILRLRQREKELLHERQMLKDILKAIPDMLTVHDRDGNVMFSNCKPNEDCWQHHGGTKHGLRCYQCHFHGDRNCEDCYI
PDVFDSGEQRVVEMYNPDMKSFRSITVFPVRDGQGDVTMVAEYVRDVTATRNLERELRVAKEAAEAADRAKSEFLASMSH
EIRTPMNGVLGMLDLAMTTSLDEEQREYLEAVQNSAEALLSLINDILDFSKIEAGMVELDQQVFRLSKRLSSLHTMFVHR
AAERNLEFAINISPDVPDGLSGDPLRLRQIVVNLLDNAFKFTDQGQVVLSVEVLERGAENVLLQFSVQDTGPGILERHQE
RIFDSFAQADASFTRRHQGSGLGLAICKRLTGLMGGDIKVRSTPGEGSTFVFSARFGVAVLDEEPVRVRSRTAEPAPVRG
RILVAEDHPMNLMFIEKFLKKQGYESVSVTDGSEVVPALTRSRFDLVLMDIAMPAMDGMEATRAVRAATGMKTPSDVPII
AMTAHAMKGDREQFLEAGMDDYIGKPINSDNLRSMIIRHLQARRKS

Sequences:

>Translated_606_residues
MPRGMACPCIHEEQRLLKNKASGLSGEFRPASCPVAYVWCRTLLSDFKQKAETHMASRQEMTESGAIAACGEGADSRSLE
AEILRLRQREKELLHERQMLKDILKAIPDMLTVHDRDGNVMFSNCKPNEDCWQHHGGTKHGLRCYQCHFHGDRNCEDCYI
PDVFDSGEQRVVEMYNPDMKSFRSITVFPVRDGQGDVTMVAEYVRDVTATRNLERELRVAKEAAEAADRAKSEFLASMSH
EIRTPMNGVLGMLDLAMTTSLDEEQREYLEAVQNSAEALLSLINDILDFSKIEAGMVELDQQVFRLSKRLSSLHTMFVHR
AAERNLEFAINISPDVPDGLSGDPLRLRQIVVNLLDNAFKFTDQGQVVLSVEVLERGAENVLLQFSVQDTGPGILERHQE
RIFDSFAQADASFTRRHQGSGLGLAICKRLTGLMGGDIKVRSTPGEGSTFVFSARFGVAVLDEEPVRVRSRTAEPAPVRG
RILVAEDHPMNLMFIEKFLKKQGYESVSVTDGSEVVPALTRSRFDLVLMDIAMPAMDGMEATRAVRAATGMKTPSDVPII
AMTAHAMKGDREQFLEAGMDDYIGKPINSDNLRSMIIRHLQARRKS
>Mature_605_residues
PRGMACPCIHEEQRLLKNKASGLSGEFRPASCPVAYVWCRTLLSDFKQKAETHMASRQEMTESGAIAACGEGADSRSLEA
EILRLRQREKELLHERQMLKDILKAIPDMLTVHDRDGNVMFSNCKPNEDCWQHHGGTKHGLRCYQCHFHGDRNCEDCYIP
DVFDSGEQRVVEMYNPDMKSFRSITVFPVRDGQGDVTMVAEYVRDVTATRNLERELRVAKEAAEAADRAKSEFLASMSHE
IRTPMNGVLGMLDLAMTTSLDEEQREYLEAVQNSAEALLSLINDILDFSKIEAGMVELDQQVFRLSKRLSSLHTMFVHRA
AERNLEFAINISPDVPDGLSGDPLRLRQIVVNLLDNAFKFTDQGQVVLSVEVLERGAENVLLQFSVQDTGPGILERHQER
IFDSFAQADASFTRRHQGSGLGLAICKRLTGLMGGDIKVRSTPGEGSTFVFSARFGVAVLDEEPVRVRSRTAEPAPVRGR
ILVAEDHPMNLMFIEKFLKKQGYESVSVTDGSEVVPALTRSRFDLVLMDIAMPAMDGMEATRAVRAATGMKTPSDVPIIA
MTAHAMKGDREQFLEAGMDDYIGKPINSDNLRSMIIRHLQARRKS

Specific function: Involved in the positive regulation of synthesis of extracellular enzymes and polysaccharide, and hence in pathogenicity. Can restore function to the non-pathogenic mutant 8237 [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1789149, Length=381, Percent_Identity=38.5826771653543, Blast_Score=235, Evalue=5e-63,
Organism=Escherichia coli, GI1788713, Length=395, Percent_Identity=33.9240506329114, Blast_Score=223, Evalue=4e-59,
Organism=Escherichia coli, GI48994928, Length=534, Percent_Identity=30.8988764044944, Blast_Score=213, Evalue=3e-56,
Organism=Escherichia coli, GI145693157, Length=245, Percent_Identity=42.0408163265306, Blast_Score=191, Evalue=1e-49,
Organism=Escherichia coli, GI87081816, Length=392, Percent_Identity=34.9489795918367, Blast_Score=186, Evalue=5e-48,
Organism=Escherichia coli, GI1786600, Length=272, Percent_Identity=30.5147058823529, Blast_Score=95, Evalue=1e-20,
Organism=Escherichia coli, GI1786783, Length=228, Percent_Identity=28.5087719298246, Blast_Score=91, Evalue=2e-19,
Organism=Escherichia coli, GI1786912, Length=262, Percent_Identity=30.5343511450382, Blast_Score=90, Evalue=4e-19,
Organism=Escherichia coli, GI1788549, Length=364, Percent_Identity=24.7252747252747, Blast_Score=89, Evalue=8e-19,
Organism=Escherichia coli, GI1788393, Length=225, Percent_Identity=27.5555555555556, Blast_Score=84, Evalue=2e-17,
Organism=Escherichia coli, GI1790436, Length=224, Percent_Identity=27.6785714285714, Blast_Score=78, Evalue=2e-15,
Organism=Escherichia coli, GI1788394, Length=108, Percent_Identity=34.2592592592593, Blast_Score=71, Evalue=2e-13,
Organism=Escherichia coli, GI1790346, Length=223, Percent_Identity=26.457399103139, Blast_Score=70, Evalue=4e-13,
Organism=Escherichia coli, GI1789809, Length=116, Percent_Identity=34.4827586206897, Blast_Score=69, Evalue=9e-13,
Organism=Escherichia coli, GI1790300, Length=306, Percent_Identity=23.202614379085, Blast_Score=67, Evalue=3e-12,
Organism=Escherichia coli, GI1787894, Length=225, Percent_Identity=27.1111111111111, Blast_Score=65, Evalue=2e-11,
Organism=Saccharomyces cerevisiae, GI6322000, Length=122, Percent_Identity=40.1639344262295, Blast_Score=97, Evalue=9e-21,
Organism=Saccharomyces cerevisiae, GI6322044, Length=72, Percent_Identity=43.0555555555556, Blast_Score=73, Evalue=2e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR011006
- InterPro:   IPR004358
- InterPro:   IPR008207
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082
- InterPro:   IPR001789 [H]

Pfam domain/function: PF02518 HATPase_c; PF00512 HisKA; PF01627 Hpt; PF00072 Response_reg [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 67755; Mature: 67624

Theoretical pI: Translated: 5.98; Mature: 5.98

Prosite motif: PS50113 PAC ; PS50110 RESPONSE_REGULATORY ; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.0 %Cys     (Translated Protein)
4.6 %Met     (Translated Protein)
6.6 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
4.5 %Met     (Mature Protein)
6.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPRGMACPCIHEEQRLLKNKASGLSGEFRPASCPVAYVWCRTLLSDFKQKAETHMASRQE
CCCCCCCCCHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
MTESGAIAACGEGADSRSLEAEILRLRQREKELLHERQMLKDILKAIPDMLTVHDRDGNV
HHHCCCEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHEEEECCCCCE
MFSNCKPNEDCWQHHGGTKHGLRCYQCHFHGDRNCEDCYIPDVFDSGEQRVVEMYNPDMK
EECCCCCCHHHHHHCCCCCCCCEEEEEEECCCCCCCCCCCCCHHCCCHHHHHHHCCCCHH
SFRSITVFPVRDGQGDVTMVAEYVRDVTATRNLERELRVAKEAAEAADRAKSEFLASMSH
HCCCEEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
EIRTPMNGVLGMLDLAMTTSLDEEQREYLEAVQNSAEALLSLINDILDFSKIEAGMVELD
HHCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
QQVFRLSKRLSSLHTMFVHRAAERNLEFAINISPDVPDGLSGDPLRLRQIVVNLLDNAFK
HHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHE
FTDQGQVVLSVEVLERGAENVLLQFSVQDTGPGILERHQERIFDSFAQADASFTRRHQGS
ECCCCCEEEEHHHHHCCCCCEEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCC
GLGLAICKRLTGLMGGDIKVRSTPGEGSTFVFSARFGVAVLDEEPVRVRSRTAEPAPVRG
CHHHHHHHHHHHHCCCCEEEEECCCCCCEEEEEECCCEEEECCCCHHHHHCCCCCCCCCC
RILVAEDHPMNLMFIEKFLKKQGYESVSVTDGSEVVPALTRSRFDLVLMDIAMPAMDGME
EEEEECCCCCHHHHHHHHHHHCCCCEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHCCHH
ATRAVRAATGMKTPSDVPIIAMTAHAMKGDREQFLEAGMDDYIGKPINSDNLRSMIIRHL
HHHHHHHHHCCCCCCCCCEEEEEHHHHCCCHHHHHHCCCHHHCCCCCCCHHHHHHHHHHH
QARRKS
HHHCCC
>Mature Secondary Structure 
PRGMACPCIHEEQRLLKNKASGLSGEFRPASCPVAYVWCRTLLSDFKQKAETHMASRQE
CCCCCCCCHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
MTESGAIAACGEGADSRSLEAEILRLRQREKELLHERQMLKDILKAIPDMLTVHDRDGNV
HHHCCCEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHEEEECCCCCE
MFSNCKPNEDCWQHHGGTKHGLRCYQCHFHGDRNCEDCYIPDVFDSGEQRVVEMYNPDMK
EECCCCCCHHHHHHCCCCCCCCEEEEEEECCCCCCCCCCCCCHHCCCHHHHHHHCCCCHH
SFRSITVFPVRDGQGDVTMVAEYVRDVTATRNLERELRVAKEAAEAADRAKSEFLASMSH
HCCCEEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
EIRTPMNGVLGMLDLAMTTSLDEEQREYLEAVQNSAEALLSLINDILDFSKIEAGMVELD
HHCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
QQVFRLSKRLSSLHTMFVHRAAERNLEFAINISPDVPDGLSGDPLRLRQIVVNLLDNAFK
HHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHE
FTDQGQVVLSVEVLERGAENVLLQFSVQDTGPGILERHQERIFDSFAQADASFTRRHQGS
ECCCCCEEEEHHHHHCCCCCEEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCC
GLGLAICKRLTGLMGGDIKVRSTPGEGSTFVFSARFGVAVLDEEPVRVRSRTAEPAPVRG
CHHHHHHHHHHHHCCCCEEEEECCCCCCEEEEEECCCEEEECCCCHHHHHCCCCCCCCCC
RILVAEDHPMNLMFIEKFLKKQGYESVSVTDGSEVVPALTRSRFDLVLMDIAMPAMDGME
EEEEECCCCCHHHHHHHHHHHCCCCEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHCCHH
ATRAVRAATGMKTPSDVPIIAMTAHAMKGDREQFLEAGMDDYIGKPINSDNLRSMIIRHL
HHHHHHHHHCCCCCCCCCEEEEEHHHHCCCHHHHHHCCCHHHCCCCCCCHHHHHHHHHHH
QARRKS
HHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 1645442 [H]