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The map label for this gene is galE [C]

Identifier: 78357929

GI number: 78357929

Start: 2875835

End: 2876764

Strand: Reverse

Name: galE [C]

Synonym: Dde_2888

Alternate gene names: 78357929

Gene position: 2876764-2875835 (Counterclockwise)

Preceding gene: 78357930

Following gene: 78357928

Centisome position: 77.12

GC content: 45.16

Gene sequence:

>930_bases
ATGGGATCTCAGGCTATAGTGACAGGAGCTTCTGGCTTTATAGGCAGCAGTGTTGCCAGAATGCTAGCGCATAAAGGATG
GACCGTTCACGGAATTGGCTCTTCTCATCTCGCAATGGAAGCACAAGAACAGATTGGGATTAAGCACTGGGTTCAGCAAG
ACTTAACGCTGGCTAGTCTTCAGGGTTTAGCCGACAAAACGGGTGATCCTGATATAATTATCCACTGTGCAGGTGGTAGT
TCTGTTCAAGCTTCAATTTCTAACCCTTACGAAGACTTTGCTCGAACAGCCAATGCGACGCTTAATGTTCTTGAATTTAT
GCGGCGATACTCCCCAGCTTCTGCTTTAGTATATCCTTCTAGTGCTGCGGTTTATGGACAAACATCCAGTTTACCTATAG
CAGAATCGTCCACCCCAAAGCCTTTTTCACCATACGGGCATCACAAAAGGATTGCAGAAATTCTATGTGAATCTTATTCC
TTACAATGGCAACTATCTGTTTCAATAGTAAGGCTTTTTTCAGTGTATGGCGCTGGGCTAAAAAAGCAGTTGCTTTGGGA
TGCCTGCCAAAAAGCAGAACAAGGTGCCTATTCTTTTTTCGGTTCGGGGGCGGAAATTCGCGACTGGCTGCATGTTGAAG
ATGCTTCCAATCTACTCATCCTTGCAGCAGAGTATGCTTCTCCGGAATGTGTCATCATAAACGGAGGAAGTGGTGTTGGG
ACTTCTATTAATGAAATTTTAAAGTTGGTTGGCTCCCACTTTGCTTTGGTCTCAGCCCCCACTTTTTCGGGCAAAGCCAG
AGAAGGGGACCCTGATTCTTATGTTGCGGATATAACCAAGGCACAAGCATTGGGATTTATCCCTTCCTTCAGCCTTAGCG
ATGGAATAAGACAGTATGTGGAATGGTTCAAAAAGGAGTGCATGCTTTGA

Upstream 100 bases:

>100_bases
CGATTTGGGAGGCTGCCCGAAAGTTAAAAAAAAATAAAGTGCGCCCAAAAGTTATTTAACCAAAACTTATATATTTTTTC
GTTGCAGGATATTAATACCT

Downstream 100 bases:

>100_bases
TTAGAGTTGCTTGGCCTGTCGCTAATGACCCCTCCTGGGTCGCGGGCTTAAACTATTTTCGCAACCTATTGCTTGCGCTA
TTGGACAATCCCTTAAATAC

Product: putative UDP-glucose 4-epimerase

Products: NA

Alternate protein names: Galactowaldenase; UDP-galactose 4-epimerase [H]

Number of amino acids: Translated: 309; Mature: 308

Protein sequence:

>309_residues
MGSQAIVTGASGFIGSSVARMLAHKGWTVHGIGSSHLAMEAQEQIGIKHWVQQDLTLASLQGLADKTGDPDIIIHCAGGS
SVQASISNPYEDFARTANATLNVLEFMRRYSPASALVYPSSAAVYGQTSSLPIAESSTPKPFSPYGHHKRIAEILCESYS
LQWQLSVSIVRLFSVYGAGLKKQLLWDACQKAEQGAYSFFGSGAEIRDWLHVEDASNLLILAAEYASPECVIINGGSGVG
TSINEILKLVGSHFALVSAPTFSGKAREGDPDSYVADITKAQALGFIPSFSLSDGIRQYVEWFKKECML

Sequences:

>Translated_309_residues
MGSQAIVTGASGFIGSSVARMLAHKGWTVHGIGSSHLAMEAQEQIGIKHWVQQDLTLASLQGLADKTGDPDIIIHCAGGS
SVQASISNPYEDFARTANATLNVLEFMRRYSPASALVYPSSAAVYGQTSSLPIAESSTPKPFSPYGHHKRIAEILCESYS
LQWQLSVSIVRLFSVYGAGLKKQLLWDACQKAEQGAYSFFGSGAEIRDWLHVEDASNLLILAAEYASPECVIINGGSGVG
TSINEILKLVGSHFALVSAPTFSGKAREGDPDSYVADITKAQALGFIPSFSLSDGIRQYVEWFKKECML
>Mature_308_residues
GSQAIVTGASGFIGSSVARMLAHKGWTVHGIGSSHLAMEAQEQIGIKHWVQQDLTLASLQGLADKTGDPDIIIHCAGGSS
VQASISNPYEDFARTANATLNVLEFMRRYSPASALVYPSSAAVYGQTSSLPIAESSTPKPFSPYGHHKRIAEILCESYSL
QWQLSVSIVRLFSVYGAGLKKQLLWDACQKAEQGAYSFFGSGAEIRDWLHVEDASNLLILAAEYASPECVIINGGSGVGT
SINEILKLVGSHFALVSAPTFSGKAREGDPDSYVADITKAQALGFIPSFSLSDGIRQYVEWFKKECML

Specific function: Galactose metabolism; third step. [C]

COG id: COG0451

COG function: function code MG; Nucleoside-diphosphate-sugar epimerases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the sugar epimerase family [H]

Homologues:

Organism=Homo sapiens, GI42516563, Length=318, Percent_Identity=25.1572327044025, Blast_Score=91, Evalue=1e-18,
Organism=Homo sapiens, GI56237023, Length=342, Percent_Identity=26.0233918128655, Blast_Score=68, Evalue=1e-11,
Organism=Homo sapiens, GI56118217, Length=342, Percent_Identity=26.0233918128655, Blast_Score=68, Evalue=1e-11,
Organism=Homo sapiens, GI189083684, Length=342, Percent_Identity=26.0233918128655, Blast_Score=68, Evalue=1e-11,
Organism=Escherichia coli, GI1786974, Length=316, Percent_Identity=29.746835443038, Blast_Score=100, Evalue=2e-22,
Organism=Escherichia coli, GI1788353, Length=338, Percent_Identity=26.0355029585799, Blast_Score=72, Evalue=5e-14,
Organism=Caenorhabditis elegans, GI17539532, Length=318, Percent_Identity=20.7547169811321, Blast_Score=77, Evalue=1e-14,
Organism=Caenorhabditis elegans, GI17568069, Length=326, Percent_Identity=26.0736196319018, Blast_Score=75, Evalue=4e-14,
Organism=Caenorhabditis elegans, GI71982035, Length=315, Percent_Identity=26.6666666666667, Blast_Score=74, Evalue=7e-14,
Organism=Caenorhabditis elegans, GI71982038, Length=317, Percent_Identity=26.813880126183, Blast_Score=74, Evalue=9e-14,
Organism=Caenorhabditis elegans, GI115532424, Length=325, Percent_Identity=24, Blast_Score=74, Evalue=1e-13,
Organism=Saccharomyces cerevisiae, GI6319493, Length=281, Percent_Identity=28.8256227758007, Blast_Score=75, Evalue=1e-14,
Organism=Drosophila melanogaster, GI21356223, Length=320, Percent_Identity=24.375, Blast_Score=89, Evalue=4e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001509
- InterPro:   IPR016040 [H]

Pfam domain/function: PF01370 Epimerase [H]

EC number: =5.1.3.2 [H]

Molecular weight: Translated: 33158; Mature: 33027

Theoretical pI: Translated: 6.23; Mature: 6.23

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGSQAIVTGASGFIGSSVARMLAHKGWTVHGIGSSHLAMEAQEQIGIKHWVQQDLTLASL
CCCCEEEECCCCHHHHHHHHHHHHCCCEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHH
QGLADKTGDPDIIIHCAGGSSVQASISNPYEDFARTANATLNVLEFMRRYSPASALVYPS
HHHHCCCCCCCEEEEECCCCCEEECCCCCHHHHHHHHHHHHHHHHHHHHCCCCCEEEECC
SAAVYGQTSSLPIAESSTPKPFSPYGHHKRIAEILCESYSLQWQLSVSIVRLFSVYGAGL
CCEECCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCEEEHHHHHHHHHHHHCCCH
KKQLLWDACQKAEQGAYSFFGSGAEIRDWLHVEDASNLLILAAEYASPECVIINGGSGVG
HHHHHHHHHHHHHCCCHHHHCCCCHHHHHEEECCCCCEEEEEEECCCCCEEEEECCCCCC
TSINEILKLVGSHFALVSAPTFSGKAREGDPDSYVADITKAQALGFIPSFSLSDGIRQYV
CCHHHHHHHHCCCEEEEECCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCHHHHHHHHH
EWFKKECML
HHHHHHCCC
>Mature Secondary Structure 
GSQAIVTGASGFIGSSVARMLAHKGWTVHGIGSSHLAMEAQEQIGIKHWVQQDLTLASL
CCCEEEECCCCHHHHHHHHHHHHCCCEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHH
QGLADKTGDPDIIIHCAGGSSVQASISNPYEDFARTANATLNVLEFMRRYSPASALVYPS
HHHHCCCCCCCEEEEECCCCCEEECCCCCHHHHHHHHHHHHHHHHHHHHCCCCCEEEECC
SAAVYGQTSSLPIAESSTPKPFSPYGHHKRIAEILCESYSLQWQLSVSIVRLFSVYGAGL
CCEECCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCEEEHHHHHHHHHHHHCCCH
KKQLLWDACQKAEQGAYSFFGSGAEIRDWLHVEDASNLLILAAEYASPECVIINGGSGVG
HHHHHHHHHHHHHCCCHHHHCCCCHHHHHEEECCCCCEEEEEEECCCCCEEEEECCCCCC
TSINEILKLVGSHFALVSAPTFSGKAREGDPDSYVADITKAQALGFIPSFSLSDGIRQYV
CCHHHHHHHHCCCEEEEECCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCHHHHHHHHH
EWFKKECML
HHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]