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The map label for this gene is arsB [H]

Identifier: 78357833

GI number: 78357833

Start: 2785456

End: 2786544

Strand: Direct

Name: arsB [H]

Synonym: Dde_2791

Alternate gene names: 78357833

Gene position: 2785456-2786544 (Clockwise)

Preceding gene: 78357832

Following gene: 78357834

Centisome position: 74.67

GC content: 51.7

Gene sequence:

>1089_bases
ATGCACGAATCCGTAGTAAAAAAACTCTCATTTCTGGATCGCTACCTGACGCTCTGGATATTCCTTGCCATGTTCGTCGG
TGTCGGCGGTGGGTATCTGTACCCGGACGTCAAGAATGTCATCAACTCCTTCCAGGTGGGCACCACCAACATCCCCATCG
CCATCGGCTTGATTCTCATGATGTACCCCCCGCTCGCCAAGGTGAAATACGAGCAACTCGGACAGGTATTCAGAAATTTC
AAGGTGCTCGCATTGTCCCTTGTACAGAACTGGATTATCGGCCCCATCCTCATGTTCGGCCTCGCCATCACGTTCCTGTC
TGGATACCACGAATACATGGTGGGGCTGATACTCATCGGCCTGGCGCGTTGCATCGCAATGGTCATCGTCTGGAACGATC
TTGCCAAAGGCGACACCGAGTATTGTGCCGGACTGGTCGCCTTCAACTCCATTTTTCAGGTGATCTTCTTCTCCGTGTAT
GCCTATCTTTTCATCACCGTGCTTCCCGGTTGGTTCGGCCTGAAAGGCGTCGTAGTGGATATCTCCATCGGCCAGATCGC
GGAAAGTGTGTTCATCTATCTTGGCATCCCGTTCATCGCTGGCATGCTCACACGGTTTATGGGACTCAAACTCAAGGGGC
AGGAGTGGTATGAGAATACGTTCATTCCCCGCATCAGTCCGCTGACGCTGGTCTTCCTTCTGTTCACGATTCTGGTGATG
TTTTCCCTCAAGGGCGAGAAGGTCATCCAGCTTCCGTTTGATGTGATCCGTATCGCTATTCCCCTGACCATCTACTTCCT
GGTCATGTTCCTCGTATCTTTTTACCTCTCTTACAAGGCCGACGCCACGTATGAGCAAGCCACCACGCTTAGTTTTACGG
CAGCGTCCAACAACTTCGAGCTTGCCATCGCGGTTGCTATTGCCGTCTTTGGCATTAATTCCGGTGAAGCTTTTGCTGCG
GTTATCGGTCCACTTGTTGAAGTGCCCGTGCTCATAGCCCTAGTCAATGTGGCCTTGCACTTCAAACGGAAGTATTTCCC
CAAGGCGGTGGAAACCATTGCCGGTGTCTGTCATGTCAAATGTGATTAA

Upstream 100 bases:

>100_bases
CGCAAGTTCTCCAAGCCATGAAGGATTATCAGTGTCTTTGTCACTATCTCGAAACCAAGAGCACTGAAGAATGTGATTAA
TTGGTCCACAAGGAGCAACC

Downstream 100 bases:

>100_bases
GCGATCTCTTTAAGAGAAGTGTGACTATGGAAAAAGTTCTCTTCATCTGCACCCATAATAGCGCCCCAGTCAAATGGCCA
AAGCCGACCTCAAACAACTC

Product: arsenical-resistance protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 362; Mature: 362

Protein sequence:

>362_residues
MHESVVKKLSFLDRYLTLWIFLAMFVGVGGGYLYPDVKNVINSFQVGTTNIPIAIGLILMMYPPLAKVKYEQLGQVFRNF
KVLALSLVQNWIIGPILMFGLAITFLSGYHEYMVGLILIGLARCIAMVIVWNDLAKGDTEYCAGLVAFNSIFQVIFFSVY
AYLFITVLPGWFGLKGVVVDISIGQIAESVFIYLGIPFIAGMLTRFMGLKLKGQEWYENTFIPRISPLTLVFLLFTILVM
FSLKGEKVIQLPFDVIRIAIPLTIYFLVMFLVSFYLSYKADATYEQATTLSFTAASNNFELAIAVAIAVFGINSGEAFAA
VIGPLVEVPVLIALVNVALHFKRKYFPKAVETIAGVCHVKCD

Sequences:

>Translated_362_residues
MHESVVKKLSFLDRYLTLWIFLAMFVGVGGGYLYPDVKNVINSFQVGTTNIPIAIGLILMMYPPLAKVKYEQLGQVFRNF
KVLALSLVQNWIIGPILMFGLAITFLSGYHEYMVGLILIGLARCIAMVIVWNDLAKGDTEYCAGLVAFNSIFQVIFFSVY
AYLFITVLPGWFGLKGVVVDISIGQIAESVFIYLGIPFIAGMLTRFMGLKLKGQEWYENTFIPRISPLTLVFLLFTILVM
FSLKGEKVIQLPFDVIRIAIPLTIYFLVMFLVSFYLSYKADATYEQATTLSFTAASNNFELAIAVAIAVFGINSGEAFAA
VIGPLVEVPVLIALVNVALHFKRKYFPKAVETIAGVCHVKCD
>Mature_362_residues
MHESVVKKLSFLDRYLTLWIFLAMFVGVGGGYLYPDVKNVINSFQVGTTNIPIAIGLILMMYPPLAKVKYEQLGQVFRNF
KVLALSLVQNWIIGPILMFGLAITFLSGYHEYMVGLILIGLARCIAMVIVWNDLAKGDTEYCAGLVAFNSIFQVIFFSVY
AYLFITVLPGWFGLKGVVVDISIGQIAESVFIYLGIPFIAGMLTRFMGLKLKGQEWYENTFIPRISPLTLVFLLFTILVM
FSLKGEKVIQLPFDVIRIAIPLTIYFLVMFLVSFYLSYKADATYEQATTLSFTAASNNFELAIAVAIAVFGINSGEAFAA
VIGPLVEVPVLIALVNVALHFKRKYFPKAVETIAGVCHVKCD

Specific function: Seems to confer resistance to arsenite by allowing cells to extrude this compound. Could be part of an arsenite extrusion pump [H]

COG id: COG0798

COG function: function code P; Arsenite efflux pump ACR3 and related permeases

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ACR3 family [H]

Homologues:

Organism=Saccharomyces cerevisiae, GI6325459, Length=327, Percent_Identity=35.7798165137615, Blast_Score=177, Evalue=3e-45,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004706
- InterPro:   IPR002657 [H]

Pfam domain/function: PF01758 SBF [H]

EC number: NA

Molecular weight: Translated: 40273; Mature: 40273

Theoretical pI: Translated: 8.52; Mature: 8.52

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MHESVVKKLSFLDRYLTLWIFLAMFVGVGGGYLYPDVKNVINSFQVGTTNIPIAIGLILM
CCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHCCCCCCCCHHHHHHHHH
MYPPLAKVKYEQLGQVFRNFKVLALSLVQNWIIGPILMFGLAITFLSGYHEYMVGLILIG
HCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LARCIAMVIVWNDLAKGDTEYCAGLVAFNSIFQVIFFSVYAYLFITVLPGWFGLKGVVVD
HHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEE
ISIGQIAESVFIYLGIPFIAGMLTRFMGLKLKGQEWYENTFIPRISPLTLVFLLFTILVM
EEHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHCCCCCCCHHHHHHHHHHHHHHH
FSLKGEKVIQLPFDVIRIAIPLTIYFLVMFLVSFYLSYKADATYEQATTLSFTAASNNFE
HHCCCCEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHEEEEEECCCCCH
LAIAVAIAVFGINSGEAFAAVIGPLVEVPVLIALVNVALHFKRKYFPKAVETIAGVCHVK
HHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCEE
CD
CC
>Mature Secondary Structure
MHESVVKKLSFLDRYLTLWIFLAMFVGVGGGYLYPDVKNVINSFQVGTTNIPIAIGLILM
CCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHCCCCCCCCHHHHHHHHH
MYPPLAKVKYEQLGQVFRNFKVLALSLVQNWIIGPILMFGLAITFLSGYHEYMVGLILIG
HCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LARCIAMVIVWNDLAKGDTEYCAGLVAFNSIFQVIFFSVYAYLFITVLPGWFGLKGVVVD
HHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEE
ISIGQIAESVFIYLGIPFIAGMLTRFMGLKLKGQEWYENTFIPRISPLTLVFLLFTILVM
EEHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHCCCCCCCHHHHHHHHHHHHHHH
FSLKGEKVIQLPFDVIRIAIPLTIYFLVMFLVSFYLSYKADATYEQATTLSFTAASNNFE
HHCCCCEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHEEEEEECCCCCH
LAIAVAIAVFGINSGEAFAAVIGPLVEVPVLIALVNVALHFKRKYFPKAVETIAGVCHVK
HHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCEE
CD
CC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7704261; 8969508; 9384377; 7489895; 9537360 [H]