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The map label for this gene is comM [H]

Identifier: 78357815

GI number: 78357815

Start: 2776007

End: 2776882

Strand: Reverse

Name: comM [H]

Synonym: Dde_2773

Alternate gene names: 78357815

Gene position: 2776882-2776007 (Counterclockwise)

Preceding gene: 78357821

Following gene: 78357813

Centisome position: 74.44

GC content: 61.07

Gene sequence:

>876_bases
ATGATCGGCCCTCCCGGCAGTGGCAAGACCATGCTCGCGCAGCGTATTCCCACGGTTCTGCCACCGCTTTCGTTTACCGA
GGCGCTGGAGGTGACCAAGATTTATTCCGTGGCGGGACAGCTGGGGGCTGAAACCGCGCTGGTAACGCAGCGGCCGTTCC
GCACCCCGCATCATACCATATCAGACCCCGGACTGGTGGGTGGCGGTACGCATCCGCGTCCGGGCGAAGTTTCCATGGCA
CACAGGGGCGTGCTGTTTCTGGACGAGTTGCCGGAGTTTCGTAAAAGTGTGCTGGAGGTTATGCGTCAGCCGCTGGAAGA
CGGCACGGTAACCATCTCACGCGCGGCCCTGTCGTTAAGCTATCCCGCGGATTTTATGCTGGTGGCGGCCATGAACCCCT
GTCCTTGCGGGTATCTTTCCGACGAGCGCCATGTGTGCCATTGCACGGCGGCTCAGATACAGCGCTATCGTTCGCGTCTT
TCAGGGCCTTTGCTTGACCGGATTGATCTGCATGTGGAAGTGCCTGCCGTGCAGTACGATGACCTGCGCCATACCGGCAG
GGGGGATTCTTCTGCTGCCATGCGCGAGCGCATTCTGCAGGCCCGTGAACGGCAGGACAAACGGTATCAGGGCACACCGT
GTGTGACCAATGCCGACCTTTCCGGCCGGTGGCTGGAAGAATACTGCCGGCTGGGCTCTGCAGAGCATGTCTTTCTGGAA
AAAGCGGTCAGCGCGCTGGCTCTTTCCGCCCGCGCCTATACCCGCATTCTGCGCATTGCGCGCACCATCGCAGACCTTGC
CGGGCACGATGCCATAACCTGTGCCGGACTGGCCGAAGCCGTCAATTGCCGGACTCTGGACAGACAGCGTCTGTAA

Upstream 100 bases:

>100_bases
GTGTTATCGACTGCCATAGTTGATTTGTTCCTCCTCCTTCTTCTTTCTGAAGGCCGAAACATATCAAGAGGCTTTCGGGT
ATTCAAGACACAACTTGCTG

Downstream 100 bases:

>100_bases
CCGGTCATCATTCAGAGACAGGCTGTTATGCAGGCAGGGTCTGTGCGGGGCAGCAAGAAAAAGCACCCGCCGGAAACCGG
AGTGGCATGTGTCAGACGGT

Product: competence protein ComM

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 291; Mature: 291

Protein sequence:

>291_residues
MIGPPGSGKTMLAQRIPTVLPPLSFTEALEVTKIYSVAGQLGAETALVTQRPFRTPHHTISDPGLVGGGTHPRPGEVSMA
HRGVLFLDELPEFRKSVLEVMRQPLEDGTVTISRAALSLSYPADFMLVAAMNPCPCGYLSDERHVCHCTAAQIQRYRSRL
SGPLLDRIDLHVEVPAVQYDDLRHTGRGDSSAAMRERILQARERQDKRYQGTPCVTNADLSGRWLEEYCRLGSAEHVFLE
KAVSALALSARAYTRILRIARTIADLAGHDAITCAGLAEAVNCRTLDRQRL

Sequences:

>Translated_291_residues
MIGPPGSGKTMLAQRIPTVLPPLSFTEALEVTKIYSVAGQLGAETALVTQRPFRTPHHTISDPGLVGGGTHPRPGEVSMA
HRGVLFLDELPEFRKSVLEVMRQPLEDGTVTISRAALSLSYPADFMLVAAMNPCPCGYLSDERHVCHCTAAQIQRYRSRL
SGPLLDRIDLHVEVPAVQYDDLRHTGRGDSSAAMRERILQARERQDKRYQGTPCVTNADLSGRWLEEYCRLGSAEHVFLE
KAVSALALSARAYTRILRIARTIADLAGHDAITCAGLAEAVNCRTLDRQRL
>Mature_291_residues
MIGPPGSGKTMLAQRIPTVLPPLSFTEALEVTKIYSVAGQLGAETALVTQRPFRTPHHTISDPGLVGGGTHPRPGEVSMA
HRGVLFLDELPEFRKSVLEVMRQPLEDGTVTISRAALSLSYPADFMLVAAMNPCPCGYLSDERHVCHCTAAQIQRYRSRL
SGPLLDRIDLHVEVPAVQYDDLRHTGRGDSSAAMRERILQARERQDKRYQGTPCVTNADLSGRWLEEYCRLGSAEHVFLE
KAVSALALSARAYTRILRIARTIADLAGHDAITCAGLAEAVNCRTLDRQRL

Specific function: Induced during competence development. Not needed for DNA uptake. May be involved in a recombination step [H]

COG id: COG0606

COG function: function code O; Predicted ATPase with chaperone activity

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the Mg-chelatase subunits D/I family. ComM subfamily [H]

Homologues:

Organism=Escherichia coli, GI145693202, Length=289, Percent_Identity=47.0588235294118, Blast_Score=248, Evalue=3e-67,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR001208
- InterPro:   IPR004482
- InterPro:   IPR000523
- InterPro:   IPR020568 [H]

Pfam domain/function: PF01078 Mg_chelatase [H]

EC number: NA

Molecular weight: Translated: 31965; Mature: 31965

Theoretical pI: Translated: 8.02; Mature: 8.02

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.7 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
5.2 %Cys+Met (Translated Protein)
2.7 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
5.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIGPPGSGKTMLAQRIPTVLPPLSFTEALEVTKIYSVAGQLGAETALVTQRPFRTPHHTI
CCCCCCCCCHHHHHHCHHHCCCCCHHHHHHHHHHHHHHHHHCCCHHEECCCCCCCCCCCC
SDPGLVGGGTHPRPGEVSMAHRGVLFLDELPEFRKSVLEVMRQPLEDGTVTISRAALSLS
CCCCCCCCCCCCCCCCCCHHHCCCHHHHHHHHHHHHHHHHHHCCCCCCCEEEEHHEEEEC
YPADFMLVAAMNPCPCGYLSDERHVCHCTAAQIQRYRSRLSGPLLDRIDLHVEVPAVQYD
CCCCEEEEEECCCCCCCCCCCCCCEEHHHHHHHHHHHHHHCCCCHHHEEEEEECCCCCHH
DLRHTGRGDSSAAMRERILQARERQDKRYQGTPCVTNADLSGRWLEEYCRLGSAEHVFLE
CCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCEECCCCCCHHHHHHHCCCCCHHHHHH
KAVSALALSARAYTRILRIARTIADLAGHDAITCAGLAEAVNCRTLDRQRL
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MIGPPGSGKTMLAQRIPTVLPPLSFTEALEVTKIYSVAGQLGAETALVTQRPFRTPHHTI
CCCCCCCCCHHHHHHCHHHCCCCCHHHHHHHHHHHHHHHHHCCCHHEECCCCCCCCCCCC
SDPGLVGGGTHPRPGEVSMAHRGVLFLDELPEFRKSVLEVMRQPLEDGTVTISRAALSLS
CCCCCCCCCCCCCCCCCCHHHCCCHHHHHHHHHHHHHHHHHHCCCCCCCEEEEHHEEEEC
YPADFMLVAAMNPCPCGYLSDERHVCHCTAAQIQRYRSRLSGPLLDRIDLHVEVPAVQYD
CCCCEEEEEECCCCCCCCCCCCCCEEHHHHHHHHHHHHHHCCCCHHHEEEEEECCCCCHH
DLRHTGRGDSSAAMRERILQARERQDKRYQGTPCVTNADLSGRWLEEYCRLGSAEHVFLE
CCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCEECCCCCCHHHHHHHCCCCCHHHHHH
KAVSALALSARAYTRILRIARTIADLAGHDAITCAGLAEAVNCRTLDRQRL
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7542800; 9457884 [H]