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The map label for this gene is zraS [C]

Identifier: 78357729

GI number: 78357729

Start: 2693625

End: 2694758

Strand: Reverse

Name: zraS [C]

Synonym: Dde_2687

Alternate gene names: 78357729

Gene position: 2694758-2693625 (Counterclockwise)

Preceding gene: 78357730

Following gene: 78357728

Centisome position: 72.24

GC content: 54.76

Gene sequence:

>1134_bases
ATGCCTGCTGAAACACACTTTGCCCCCGCACGACGCAGTACATTGCCGGAGCTTGCACGCCAGCGCAGGCTTTTTGCAGA
TGAAACACTGGTCACACTGCTCGATTCAGTAACGGATATTGTCGTTATTCTTAATGATACAAGACAGATTGTTTTTGCAA
ACCGCAATCTGTTGTCTCTGCTGGGTGAAAAAACTGCAGACAGGGTGATAGGCATGCGCCCGGGCGAACTGTTTTCGTGC
GAACACGCCTGCTGCACTGCGGCCGGATGCGGCACCTCGCCCGCATGCCACAGCTGTGAAGCCGTGCACGCCATACTGTG
CGGACTGAGCGGCAGACGCCGTGAAGCGGAATGCCGCATCACCAAGCGCGAAGATGAAGTGCTGGTGGCCTATGACCTGA
AAATCTGCGCTTCACCGCTTACTGTGCACGATGAGCATTTTGTATTGTTCGCCATCCACGATATCAGCGACGAAAAAAGA
CGCCGGGCACTGGAGCGGATTTTCTTCCATGACATACTGAATACGGCAGGCGGACTGCAGAACCTTGCGCAGATGATTCT
TGAAGAGGTTCCGCTGGACCTGAAGGGTGAAAGTCTGCTTATGCATCGCTTTTCCAAAGAACTGGTAGACGAGATCATGG
CTCAGCGTCTGCTTCTGGCCGCAGAATCGGATGAACTGAGTATCCGCCCCGCACGGTTGTGTCTGGCTGAACTGATGAGT
GATGTGCTGGAATCGGTACAGCAGATGGAAATGGCCCAAGGGGTGCATTTCGACGTGCAGGCACCGGCGGAAAGTCTGAT
GATAGAAAGCGATCAGACCTTGTTGCGCCGTGTCATGCTGAACATGCTGAAAAACGCCATGGAAGCCTCGCCGCAGGACG
GTTGCGTGGCGGTGGGCTGCTGTCCGGCAGACGGCGGCGCAGAATTTTACACCAGAAACGACTGCGTCATACCAGAGGCA
CATCGGTGGCTTGTATTCCAGCGTTCTTTTTCTACAAAGGGAACGGGGCGCGGGCTTGGCACATACAGCATGAAGCTGCT
TACCAACAACTATCTCAAAGGTTCCGTAGGATTTGAAAGCCGCGAGGGTGAAGGCACCACATTCCGCCTGTGGCTTCCCG
CGGTGCTGAGCTGA

Upstream 100 bases:

>100_bases
TGCCCTGCAGGTCTTTTTTTATACACAGCGCCGGAGTGCTTGGAAATGCTGTTGTTTTATTGTAGGTCATTGCCTACAGA
CAATTCATTTTGAGGTTGCT

Downstream 100 bases:

>100_bases
GCACGACGTTTTCCGCCGCACGGGAGCCGCACGGGAGCCGGCACGGTGCGGTCCGGCGATGCATGCTGTTAGGGGGGGAT
CTGTTTTCATGCACCGCTGA

Product: PAS/PAC sensor signal transduction histidine kinase

Products: NA

Alternate protein names: Sensor Histidine Kinase; PAS/PAC Sensor Signal Transduction Histidine Kinase; Sensory Transduction Histidine Kinase; Pas/Pac Sensor Signal Transduction Histidine Kinase; PAS Sensor Protein; Sporulation Sensor Histidine Kinase A

Number of amino acids: Translated: 377; Mature: 376

Protein sequence:

>377_residues
MPAETHFAPARRSTLPELARQRRLFADETLVTLLDSVTDIVVILNDTRQIVFANRNLLSLLGEKTADRVIGMRPGELFSC
EHACCTAAGCGTSPACHSCEAVHAILCGLSGRRREAECRITKREDEVLVAYDLKICASPLTVHDEHFVLFAIHDISDEKR
RRALERIFFHDILNTAGGLQNLAQMILEEVPLDLKGESLLMHRFSKELVDEIMAQRLLLAAESDELSIRPARLCLAELMS
DVLESVQQMEMAQGVHFDVQAPAESLMIESDQTLLRRVMLNMLKNAMEASPQDGCVAVGCCPADGGAEFYTRNDCVIPEA
HRWLVFQRSFSTKGTGRGLGTYSMKLLTNNYLKGSVGFESREGEGTTFRLWLPAVLS

Sequences:

>Translated_377_residues
MPAETHFAPARRSTLPELARQRRLFADETLVTLLDSVTDIVVILNDTRQIVFANRNLLSLLGEKTADRVIGMRPGELFSC
EHACCTAAGCGTSPACHSCEAVHAILCGLSGRRREAECRITKREDEVLVAYDLKICASPLTVHDEHFVLFAIHDISDEKR
RRALERIFFHDILNTAGGLQNLAQMILEEVPLDLKGESLLMHRFSKELVDEIMAQRLLLAAESDELSIRPARLCLAELMS
DVLESVQQMEMAQGVHFDVQAPAESLMIESDQTLLRRVMLNMLKNAMEASPQDGCVAVGCCPADGGAEFYTRNDCVIPEA
HRWLVFQRSFSTKGTGRGLGTYSMKLLTNNYLKGSVGFESREGEGTTFRLWLPAVLS
>Mature_376_residues
PAETHFAPARRSTLPELARQRRLFADETLVTLLDSVTDIVVILNDTRQIVFANRNLLSLLGEKTADRVIGMRPGELFSCE
HACCTAAGCGTSPACHSCEAVHAILCGLSGRRREAECRITKREDEVLVAYDLKICASPLTVHDEHFVLFAIHDISDEKRR
RALERIFFHDILNTAGGLQNLAQMILEEVPLDLKGESLLMHRFSKELVDEIMAQRLLLAAESDELSIRPARLCLAELMSD
VLESVQQMEMAQGVHFDVQAPAESLMIESDQTLLRRVMLNMLKNAMEASPQDGCVAVGCCPADGGAEFYTRNDCVIPEAH
RWLVFQRSFSTKGTGRGLGTYSMKLLTNNYLKGSVGFESREGEGTTFRLWLPAVLS

Specific function: Member Of The Two-Component Regulatory System Zras/Zrar. May Function As A Membrane-Associated Protein Kinase That Phosphorylates Zrar In Response To High Concentrations Of Zinc Or Lead In The Medium. [C]

COG id: COG0642

COG function: function code T; Signal transduction histidine kinase

Gene ontology:

Cell location: Integral Membrane Protein. Inner Membrane [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Escherichia coli, GI1790436, Length=211, Percent_Identity=27.9620853080569, Blast_Score=63, Evalue=4e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

NA

Pfam domain/function: NA

EC number: 2.7.3.- [C]

Molecular weight: Translated: 41898; Mature: 41767

Theoretical pI: Translated: 5.45; Mature: 5.45

Prosite motif: PS50112 PAS ; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.7 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
7.2 %Cys+Met (Translated Protein)
3.7 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
6.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPAETHFAPARRSTLPELARQRRLFADETLVTLLDSVTDIVVILNDTRQIVFANRNLLSL
CCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEEEECCCEEEEECCHHHHH
LGEKTADRVIGMRPGELFSCEHACCTAAGCGTSPACHSCEAVHAILCGLSGRRREAECRI
HHHHHHHHHCCCCCCCCCCCCHHHHHCCCCCCCCCHHHHHHHHHHHHCCCCCCCCCCEEE
TKREDEVLVAYDLKICASPLTVHDEHFVLFAIHDISDEKRRRALERIFFHDILNTAGGLQ
ECCCCCEEEEEEHHHHCCCCEECCCCEEEEEEECCCHHHHHHHHHHHHHHHHHHHCCCHH
NLAQMILEEVPLDLKGESLLMHRFSKELVDEIMAQRLLLAAESDELSIRPARLCLAELMS
HHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHH
DVLESVQQMEMAQGVHFDVQAPAESLMIESDQTLLRRVMLNMLKNAMEASPQDGCVAVGC
HHHHHHHHHHHHCCCCEEECCCHHHHEECCHHHHHHHHHHHHHHHHHHCCCCCCEEEEEE
CPADGGAEFYTRNDCVIPEAHRWLVFQRSFSTKGTGRGLGTYSMKLLTNNYLKGSVGFES
ECCCCCCCEEECCCCCCCCCCEEEEEEECCCCCCCCCCCCCEEEHHHHCCCEECCCCCCC
REGEGTTFRLWLPAVLS
CCCCCCEEEEECCHHCC
>Mature Secondary Structure 
PAETHFAPARRSTLPELARQRRLFADETLVTLLDSVTDIVVILNDTRQIVFANRNLLSL
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEEEECCCEEEEECCHHHHH
LGEKTADRVIGMRPGELFSCEHACCTAAGCGTSPACHSCEAVHAILCGLSGRRREAECRI
HHHHHHHHHCCCCCCCCCCCCHHHHHCCCCCCCCCHHHHHHHHHHHHCCCCCCCCCCEEE
TKREDEVLVAYDLKICASPLTVHDEHFVLFAIHDISDEKRRRALERIFFHDILNTAGGLQ
ECCCCCEEEEEEHHHHCCCCEECCCCEEEEEEECCCHHHHHHHHHHHHHHHHHHHCCCHH
NLAQMILEEVPLDLKGESLLMHRFSKELVDEIMAQRLLLAAESDELSIRPARLCLAELMS
HHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHH
DVLESVQQMEMAQGVHFDVQAPAESLMIESDQTLLRRVMLNMLKNAMEASPQDGCVAVGC
HHHHHHHHHHHHCCCCEEECCCHHHHEECCHHHHHHHHHHHHHHHHHHCCCCCCEEEEEE
CPADGGAEFYTRNDCVIPEAHRWLVFQRSFSTKGTGRGLGTYSMKLLTNNYLKGSVGFES
ECCCCCCCEEECCCCCCCCCCEEEEEEECCCCCCCCCCCCCEEEHHHHCCCEECCCCCCC
REGEGTTFRLWLPAVLS
CCCCCCEEEEECCHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA