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The map label for this gene is mltF [H]

Identifier: 78357594

GI number: 78357594

Start: 2568890

End: 2570443

Strand: Direct

Name: mltF [H]

Synonym: Dde_2552

Alternate gene names: 78357594

Gene position: 2568890-2570443 (Clockwise)

Preceding gene: 78357582

Following gene: 78357595

Centisome position: 68.87

GC content: 61.13

Gene sequence:

>1554_bases
ATGCCGCGCAAACACGGGAGCCGTACTCTGAAAACCCGCGCGCTGTACGCCATTACCGGCATCACCGTTTGCGTCCTGCT
GGCCGCTCTGGTCTTTTTTGCAGTACGCCATCTGCCGGAACCTGCCGCCCCGCTGCCCGGACAACAGACGGAAAACGGCC
GCCAGTTACGGCGCCGCCTGCTTGAGCAGGGTATTTTCAAACCGTTCACCGGCGATATCGACGCCATCAGACGACGCAAA
GTGCTGCGCATGCTGGTGCCGTACAACCGCACAGACTATTTTCTGGACGGCGCCGCCCAGCGCGGCCTTGCCTACGACAC
CGGCACCGCTTTCGCCGGCTGGCTAAACAAACGGCTGGGACTTACCGGCACACGCCGCATCTCGCTGCTGTTTATTCCGG
CAGCCCCCGACGATATGCTGCGCATGCTGCGCGAAGGACAGGGGGATATGATCGGCTACGAATGCCTTGTGCCCGGAACA
CTGCCCGACGACGTGACCGCAGCCGGACCGTGGTCGCGCACCGCACAGGTTGTGGTGGTCTCGCGGCAGTCCGTGCCCCC
CCTGCAATCCCTTGCGGAGCTCTCCGGAAAAACTGTGTATGTGCTGAAAAACAGTGCTGTCGCACAAATTCTGGACGCCA
CAGCGCGCACTATGACAACCACGGGGATTCCTGTGCGCGGCATGGCGGTGGAAGGCGGACTGACGCAGGAAGACCTGCTG
GACATGGTGAGCGGCGGCAGCATAGCCTTTGCCGCGGCAGAAGCGGATAAAGCAGCGCTGTGGGCGCGCGTGCTGCCCGA
CCTGCAGGTACACGCCAACGCCCCCCTGACAACGAACGCCACCCGCGCATGGCTGCTGCGCAGTGACACGCCGCAGCTGA
ACACCCTGTGCAACGAATTCATACGGCAGTACAGACGCACCACCGACTATGCATGGCTGCGGCAGAAATATTTCAGCCGC
ACCACATATGTGGCGGATGGCGGCCGTTCGCAGGAACTTGCCAGACTGGAGGCCACGCTGCCGCTGTTCATAAAGTACGG
CGAGCAGTACGATTTTGCCCCGCTGCTGCTGGCGGCGCAGGGGTATCAGGAATCGCGCCTGAACCAGCAGGCACGCAGCC
ACAAGGGGGCTGTGGGCATCATGCAGCTGCTGCCGGCTACGGCTGCCGCCAGCCCTGTGGGCATCACCGATATTTCAACA
CCGGAAAACAACATCCATGCCGGAGTGAAGTACCTCGCCCATCTGCGCGACACCTATTTCGATTCCGAAGGCATAAACTA
TCTGGACCGGATGCTGCTTTCGTTCGCCGCATACAACGCGGGGCCCGGCAATATCCGCAAGGCGCGGCGAGCCACAGCGC
AGATGGAACTGAACCCCGATGTATGGCGCAATAACGTGGAAAAAGGCGTCGCTGCCACCATCGGACAGGAACCTGTACGC
TATGTGCGCAATATAATAACTTATTATATTGTTTTTCAGTTGGTGCGCGAACATCGCCACATCCGCGATGCGGCTCTGCA
GCAGCTGGACATCGCGCCGCACTTCACCCGCTGA

Upstream 100 bases:

>100_bases
CGCTGCGGACGAGACTGGACAAGTGTCAATGAATGCCGCATGATAGCTTTACCGCACACAACCTGTTTTTTTCGCGCCGC
CGCCCGCACCCTGTGGTGCC

Downstream 100 bases:

>100_bases
TCCGTGCCGCGCCGTGCCTCCTGCTGCAGCTGCTCCAAACGGCGCGCACCGCTCAAAAAATATCGCTTAAATCAAGACTG
TTACGCCATGGCTGCCGCAA

Product: transglycosylase SLT domain/extracellular solute-binding domain-containing protein

Products: NA

Alternate protein names: Murein lyase F [H]

Number of amino acids: Translated: 517; Mature: 516

Protein sequence:

>517_residues
MPRKHGSRTLKTRALYAITGITVCVLLAALVFFAVRHLPEPAAPLPGQQTENGRQLRRRLLEQGIFKPFTGDIDAIRRRK
VLRMLVPYNRTDYFLDGAAQRGLAYDTGTAFAGWLNKRLGLTGTRRISLLFIPAAPDDMLRMLREGQGDMIGYECLVPGT
LPDDVTAAGPWSRTAQVVVVSRQSVPPLQSLAELSGKTVYVLKNSAVAQILDATARTMTTTGIPVRGMAVEGGLTQEDLL
DMVSGGSIAFAAAEADKAALWARVLPDLQVHANAPLTTNATRAWLLRSDTPQLNTLCNEFIRQYRRTTDYAWLRQKYFSR
TTYVADGGRSQELARLEATLPLFIKYGEQYDFAPLLLAAQGYQESRLNQQARSHKGAVGIMQLLPATAAASPVGITDIST
PENNIHAGVKYLAHLRDTYFDSEGINYLDRMLLSFAAYNAGPGNIRKARRATAQMELNPDVWRNNVEKGVAATIGQEPVR
YVRNIITYYIVFQLVREHRHIRDAALQQLDIAPHFTR

Sequences:

>Translated_517_residues
MPRKHGSRTLKTRALYAITGITVCVLLAALVFFAVRHLPEPAAPLPGQQTENGRQLRRRLLEQGIFKPFTGDIDAIRRRK
VLRMLVPYNRTDYFLDGAAQRGLAYDTGTAFAGWLNKRLGLTGTRRISLLFIPAAPDDMLRMLREGQGDMIGYECLVPGT
LPDDVTAAGPWSRTAQVVVVSRQSVPPLQSLAELSGKTVYVLKNSAVAQILDATARTMTTTGIPVRGMAVEGGLTQEDLL
DMVSGGSIAFAAAEADKAALWARVLPDLQVHANAPLTTNATRAWLLRSDTPQLNTLCNEFIRQYRRTTDYAWLRQKYFSR
TTYVADGGRSQELARLEATLPLFIKYGEQYDFAPLLLAAQGYQESRLNQQARSHKGAVGIMQLLPATAAASPVGITDIST
PENNIHAGVKYLAHLRDTYFDSEGINYLDRMLLSFAAYNAGPGNIRKARRATAQMELNPDVWRNNVEKGVAATIGQEPVR
YVRNIITYYIVFQLVREHRHIRDAALQQLDIAPHFTR
>Mature_516_residues
PRKHGSRTLKTRALYAITGITVCVLLAALVFFAVRHLPEPAAPLPGQQTENGRQLRRRLLEQGIFKPFTGDIDAIRRRKV
LRMLVPYNRTDYFLDGAAQRGLAYDTGTAFAGWLNKRLGLTGTRRISLLFIPAAPDDMLRMLREGQGDMIGYECLVPGTL
PDDVTAAGPWSRTAQVVVVSRQSVPPLQSLAELSGKTVYVLKNSAVAQILDATARTMTTTGIPVRGMAVEGGLTQEDLLD
MVSGGSIAFAAAEADKAALWARVLPDLQVHANAPLTTNATRAWLLRSDTPQLNTLCNEFIRQYRRTTDYAWLRQKYFSRT
TYVADGGRSQELARLEATLPLFIKYGEQYDFAPLLLAAQGYQESRLNQQARSHKGAVGIMQLLPATAAASPVGITDISTP
ENNIHAGVKYLAHLRDTYFDSEGINYLDRMLLSFAAYNAGPGNIRKARRATAQMELNPDVWRNNVEKGVAATIGQEPVRY
VRNIITYYIVFQLVREHRHIRDAALQQLDIAPHFTR

Specific function: Murein-degrading enzyme that degrades murein glycan strands and insoluble, high-molecular weight murein sacculi, with the concomitant formation of a 1,6-anhydromuramoyl product. Lytic transglycosylases (LTs) play an integral role in the metabolism of the

COG id: COG4623

COG function: function code M; Predicted soluble lytic transglycosylase fused to an ABC-type amino acid-binding protein

Gene ontology:

Cell location: Cell outer membrane; Peripheral membrane protein. Note=Attached to the inner leaflet of the outer membrane [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: In the C-terminal section; belongs to the transglycosylase slt family [H]

Homologues:

Organism=Escherichia coli, GI171474010, Length=461, Percent_Identity=28.1995661605206, Blast_Score=101, Evalue=1e-22,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008258
- InterPro:   IPR001638
- InterPro:   IPR000189 [H]

Pfam domain/function: PF00497 SBP_bac_3; PF01464 SLT [H]

EC number: NA

Molecular weight: Translated: 57380; Mature: 57248

Theoretical pI: Translated: 10.01; Mature: 10.01

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPRKHGSRTLKTRALYAITGITVCVLLAALVFFAVRHLPEPAAPLPGQQTENGRQLRRRL
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHH
LEQGIFKPFTGDIDAIRRRKVLRMLVPYNRTDYFLDGAAQRGLAYDTGTAFAGWLNKRLG
HHCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCEEECCHHHCCCEECCCHHHHHHHHHHCC
LTGTRRISLLFIPAAPDDMLRMLREGQGDMIGYECLVPGTLPDDVTAAGPWSRTAQVVVV
CCCCCEEEEEEECCCCHHHHHHHHCCCCCEEEEEEEECCCCCCCCCCCCCCCCCEEEEEE
SRQSVPPLQSLAELSGKTVYVLKNSAVAQILDATARTMTTTGIPVRGMAVEGGLTQEDLL
ECCCCCHHHHHHHHCCCEEEEEECCHHHHHHHHHHHHHEECCCCEEEEEECCCCCHHHHH
DMVSGGSIAFAAAEADKAALWARVLPDLQVHANAPLTTNATRAWLLRSDTPQLNTLCNEF
HHHCCCCEEEEECCCHHHHHHHHHCCCCEEECCCCCCCCCCEEEEEECCCCHHHHHHHHH
IRQYRRTTDYAWLRQKYFSRTTYVADGGRSQELARLEATLPLFIKYGEQYDFAPLLLAAQ
HHHHHHCCHHHHHHHHHHHCCEEEECCCCCHHHHHHHHCCEEEEEECCCCCCHHHHHHHC
GYQESRLNQQARSHKGAVGIMQLLPATAAASPVGITDISTPENNIHAGVKYLAHLRDTYF
CCHHHHHHHHHHHHCCHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHC
DSEGINYLDRMLLSFAAYNAGPGNIRKARRATAQMELNPDVWRNNVEKGVAATIGQEPVR
CCCCHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHEECCHHHHHHHHHHHHHHHHCHHHHH
YVRNIITYYIVFQLVREHRHIRDAALQQLDIAPHFTR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCC
>Mature Secondary Structure 
PRKHGSRTLKTRALYAITGITVCVLLAALVFFAVRHLPEPAAPLPGQQTENGRQLRRRL
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHH
LEQGIFKPFTGDIDAIRRRKVLRMLVPYNRTDYFLDGAAQRGLAYDTGTAFAGWLNKRLG
HHCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCEEECCHHHCCCEECCCHHHHHHHHHHCC
LTGTRRISLLFIPAAPDDMLRMLREGQGDMIGYECLVPGTLPDDVTAAGPWSRTAQVVVV
CCCCCEEEEEEECCCCHHHHHHHHCCCCCEEEEEEEECCCCCCCCCCCCCCCCCEEEEEE
SRQSVPPLQSLAELSGKTVYVLKNSAVAQILDATARTMTTTGIPVRGMAVEGGLTQEDLL
ECCCCCHHHHHHHHCCCEEEEEECCHHHHHHHHHHHHHEECCCCEEEEEECCCCCHHHHH
DMVSGGSIAFAAAEADKAALWARVLPDLQVHANAPLTTNATRAWLLRSDTPQLNTLCNEF
HHHCCCCEEEEECCCHHHHHHHHHCCCCEEECCCCCCCCCCEEEEEECCCCHHHHHHHHH
IRQYRRTTDYAWLRQKYFSRTTYVADGGRSQELARLEATLPLFIKYGEQYDFAPLLLAAQ
HHHHHHCCHHHHHHHHHHHCCEEEECCCCCHHHHHHHHCCEEEEEECCCCCCHHHHHHHC
GYQESRLNQQARSHKGAVGIMQLLPATAAASPVGITDISTPENNIHAGVKYLAHLRDTYF
CCHHHHHHHHHHHHCCHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHC
DSEGINYLDRMLLSFAAYNAGPGNIRKARRATAQMELNPDVWRNNVEKGVAATIGQEPVR
CCCCHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHEECCHHHHHHHHHHHHHHHHCHHHHH
YVRNIITYYIVFQLVREHRHIRDAALQQLDIAPHFTR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA