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The map label for this gene is gapA [H]

Identifier: 78357385

GI number: 78357385

Start: 2361058

End: 2362059

Strand: Direct

Name: gapA [H]

Synonym: Dde_2342

Alternate gene names: 78357385

Gene position: 2361058-2362059 (Clockwise)

Preceding gene: 78357384

Following gene: 78357389

Centisome position: 63.3

GC content: 59.98

Gene sequence:

>1002_bases
ATGGCTGTTACGCTTGGCATCAACGGGTTCGGCCGCATCGGCCGCTATCTTGTGCGCCTTCTGGCAAATGATCCCGAACT
GAATACCGCAGTGGTCAACGCCCGCGCCGACAACGAATCGCTGGCACGGCTTTTCAAATACGATTCGTGCCACGGCACCT
ACCCCGCAGAGGTAAAAGCCAACAGCGACGGCTTTACCGTGAACGGCAAGCAGATTGTCGTAACCCGTTACGGGCACAAT
GAATGGAAATGGGCTGACTACGGCGTTGATATCGCCGTGGAAAGCACGGGGACGGTAAAAGACAGGGCCGGACTTGCCCT
GCATATGGAACGGGGCGCAAAAAAGACGGTTATCAGCGCTCCCTGCGCCGATGCCGACCTGACCGTGGTAATGGGGGTCA
ACGATCATCTGTACGATCCCGCGCAGCACGATGTCATTTCCAACGCATCCTGCACCACCAACTGTCTGGCCCCCGTGGTC
AAAGTGCTTAACGACACGTTCGGCGTGCGCCACGGCCTGATGACCACCGTGCACTCATACACCATGAGCCAGCGGCTGCT
GGACGGCACGCACAAAGACCCCCGCCGCGGCAGAGCCGCCGCCATGTCCATGATTCCCACATCCACAGGCGCAGCCAAGG
CAGTGGGGCTGGTCATTCCCGAACTGGCGGGCAAGCTCAACGGCATGGCCATCCGCGTGCCCACGCCCAACGTATCGCTG
GTGGACCTCACCTGCGAGCTGGGCAAGTCCGCCACGGCGGAAGAAATCAACGCCGCTCTGCGCGAAGCCGCAGCCACCAC
GCTGAAAGGCAACATGGGCTATACCGAAGAGCCGCTGGTATCCTGCGACTACATGGGCAGCACATTCGGCGGAGTTGTTG
ACGGACCGTGCACATCTGTCATGGAAGGCAACATGGCCAAGCTGATTATCTGGTACGACAACGAAGCAGGTTTCACCAAC
CAGCTCGTGCGTCTGCTGCGCAAGGTCGGCAACAGCCTGTAG

Upstream 100 bases:

>100_bases
GGCCTATCTCAAGCCCGCCCGCGAAGCTGTGAAAAACATGGTTCAACATAAAATCCGCAACGTACTGGGTTGCTCCAACA
AGGCATAAAGGAACGCTAGC

Downstream 100 bases:

>100_bases
GCCTTTTTTCGTACATATATGCCAAAAGCCCGCCGCACACATGTGCGACGGGCTTTTTTCACATCTGCTGTCAGCGTCAG
GCAAACATGACTGCAGCCCA

Product: glyceraldehyde-3-phosphate dehydrogenase

Products: NA

Alternate protein names: NAD-dependent glyceraldehyde-3-phosphate dehydrogenase; GAPDH [H]

Number of amino acids: Translated: 333; Mature: 332

Protein sequence:

>333_residues
MAVTLGINGFGRIGRYLVRLLANDPELNTAVVNARADNESLARLFKYDSCHGTYPAEVKANSDGFTVNGKQIVVTRYGHN
EWKWADYGVDIAVESTGTVKDRAGLALHMERGAKKTVISAPCADADLTVVMGVNDHLYDPAQHDVISNASCTTNCLAPVV
KVLNDTFGVRHGLMTTVHSYTMSQRLLDGTHKDPRRGRAAAMSMIPTSTGAAKAVGLVIPELAGKLNGMAIRVPTPNVSL
VDLTCELGKSATAEEINAALREAAATTLKGNMGYTEEPLVSCDYMGSTFGGVVDGPCTSVMEGNMAKLIIWYDNEAGFTN
QLVRLLRKVGNSL

Sequences:

>Translated_333_residues
MAVTLGINGFGRIGRYLVRLLANDPELNTAVVNARADNESLARLFKYDSCHGTYPAEVKANSDGFTVNGKQIVVTRYGHN
EWKWADYGVDIAVESTGTVKDRAGLALHMERGAKKTVISAPCADADLTVVMGVNDHLYDPAQHDVISNASCTTNCLAPVV
KVLNDTFGVRHGLMTTVHSYTMSQRLLDGTHKDPRRGRAAAMSMIPTSTGAAKAVGLVIPELAGKLNGMAIRVPTPNVSL
VDLTCELGKSATAEEINAALREAAATTLKGNMGYTEEPLVSCDYMGSTFGGVVDGPCTSVMEGNMAKLIIWYDNEAGFTN
QLVRLLRKVGNSL
>Mature_332_residues
AVTLGINGFGRIGRYLVRLLANDPELNTAVVNARADNESLARLFKYDSCHGTYPAEVKANSDGFTVNGKQIVVTRYGHNE
WKWADYGVDIAVESTGTVKDRAGLALHMERGAKKTVISAPCADADLTVVMGVNDHLYDPAQHDVISNASCTTNCLAPVVK
VLNDTFGVRHGLMTTVHSYTMSQRLLDGTHKDPRRGRAAAMSMIPTSTGAAKAVGLVIPELAGKLNGMAIRVPTPNVSLV
DLTCELGKSATAEEINAALREAAATTLKGNMGYTEEPLVSCDYMGSTFGGVVDGPCTSVMEGNMAKLIIWYDNEAGFTNQ
LVRLLRKVGNSL

Specific function: More active in catabolism [H]

COG id: COG0057

COG function: function code G; Glyceraldehyde-3-phosphate dehydrogenase/erythrose-4-phosphate dehydrogenase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI7657116, Length=327, Percent_Identity=45.565749235474, Blast_Score=279, Evalue=2e-75,
Organism=Homo sapiens, GI7669492, Length=327, Percent_Identity=45.8715596330275, Blast_Score=278, Evalue=6e-75,
Organism=Escherichia coli, GI1788079, Length=331, Percent_Identity=46.2235649546828, Blast_Score=292, Evalue=2e-80,
Organism=Escherichia coli, GI1789295, Length=329, Percent_Identity=39.5136778115502, Blast_Score=239, Evalue=1e-64,
Organism=Caenorhabditis elegans, GI32566163, Length=334, Percent_Identity=45.5089820359281, Blast_Score=270, Evalue=7e-73,
Organism=Caenorhabditis elegans, GI17568413, Length=334, Percent_Identity=45.5089820359281, Blast_Score=270, Evalue=9e-73,
Organism=Caenorhabditis elegans, GI17534679, Length=338, Percent_Identity=44.9704142011834, Blast_Score=270, Evalue=9e-73,
Organism=Caenorhabditis elegans, GI17534677, Length=338, Percent_Identity=44.6745562130178, Blast_Score=269, Evalue=1e-72,
Organism=Saccharomyces cerevisiae, GI6321631, Length=335, Percent_Identity=45.6716417910448, Blast_Score=287, Evalue=2e-78,
Organism=Saccharomyces cerevisiae, GI6322468, Length=333, Percent_Identity=45.045045045045, Blast_Score=282, Evalue=5e-77,
Organism=Saccharomyces cerevisiae, GI6322409, Length=335, Percent_Identity=45.0746268656716, Blast_Score=281, Evalue=1e-76,
Organism=Drosophila melanogaster, GI17933600, Length=325, Percent_Identity=48, Blast_Score=281, Evalue=5e-76,
Organism=Drosophila melanogaster, GI18110149, Length=325, Percent_Identity=48, Blast_Score=281, Evalue=5e-76,
Organism=Drosophila melanogaster, GI85725000, Length=325, Percent_Identity=47.6923076923077, Blast_Score=280, Evalue=8e-76,
Organism=Drosophila melanogaster, GI22023983, Length=325, Percent_Identity=47.6923076923077, Blast_Score=280, Evalue=8e-76,
Organism=Drosophila melanogaster, GI19922412, Length=326, Percent_Identity=46.0122699386503, Blast_Score=278, Evalue=4e-75,

Paralogues:

None

Copy number: 220 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 1840 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 740 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 1660 Molecules/Cell In: Growth Phase, Min

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020831
- InterPro:   IPR020830
- InterPro:   IPR020829
- InterPro:   IPR020828
- InterPro:   IPR006424
- InterPro:   IPR016040 [H]

Pfam domain/function: PF02800 Gp_dh_C; PF00044 Gp_dh_N [H]

EC number: =1.2.1.12 [H]

Molecular weight: Translated: 35609; Mature: 35478

Theoretical pI: Translated: 6.93; Mature: 6.93

Prosite motif: PS00071 GAPDH

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.1 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
5.7 %Cys+Met (Translated Protein)
2.1 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
5.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAVTLGINGFGRIGRYLVRLLANDPELNTAVVNARADNESLARLFKYDSCHGTYPAEVKA
CEEEEECCCHHHHHHHHHHHHCCCCCCCEEEEEECCCHHHHHHHHHCCCCCCCCCCEEEE
NSDGFTVNGKQIVVTRYGHNEWKWADYGVDIAVESTGTVKDRAGLALHMERGAKKTVISA
CCCCEEECCCEEEEEECCCCCCEEEECCEEEEEECCCCCCCCCCEEEEECCCCCEEEEEC
PCADADLTVVMGVNDHLYDPAQHDVISNASCTTNCLAPVVKVLNDTFGVRHGLMTTVHSY
CCCCCCEEEEEECCCCCCCCHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
TMSQRLLDGTHKDPRRGRAAAMSMIPTSTGAAKAVGLVIPELAGKLNGMAIRVPTPNVSL
HHHHHHHCCCCCCCCCCHHHHHHHCCCCCCCHHHHHHHHHHHHCCCCCEEEEECCCCCEE
VDLTCELGKSATAEEINAALREAAATTLKGNMGYTEEPLVSCDYMGSTFGGVVDGPCTSV
EEEEECCCCCCCHHHHHHHHHHHHHHHEECCCCCCCCCCEEEECCCCCCCCCCCCCHHHH
MEGNMAKLIIWYDNEAGFTNQLVRLLRKVGNSL
HCCCCEEEEEEECCCCCHHHHHHHHHHHHCCCC
>Mature Secondary Structure 
AVTLGINGFGRIGRYLVRLLANDPELNTAVVNARADNESLARLFKYDSCHGTYPAEVKA
EEEEECCCHHHHHHHHHHHHCCCCCCCEEEEEECCCHHHHHHHHHCCCCCCCCCCEEEE
NSDGFTVNGKQIVVTRYGHNEWKWADYGVDIAVESTGTVKDRAGLALHMERGAKKTVISA
CCCCEEECCCEEEEEECCCCCCEEEECCEEEEEECCCCCCCCCCEEEEECCCCCEEEEEC
PCADADLTVVMGVNDHLYDPAQHDVISNASCTTNCLAPVVKVLNDTFGVRHGLMTTVHSY
CCCCCCEEEEEECCCCCCCCHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
TMSQRLLDGTHKDPRRGRAAAMSMIPTSTGAAKAVGLVIPELAGKLNGMAIRVPTPNVSL
HHHHHHHCCCCCCCCCCHHHHHHHCCCCCCCHHHHHHHHHHHHCCCCCEEEEECCCCCEE
VDLTCELGKSATAEEINAALREAAATTLKGNMGYTEEPLVSCDYMGSTFGGVVDGPCTSV
EEEEECCCCCCCHHHHHHHHHHHHHHHEECCCCCCCCCCEEEECCCCCCCCCCCCCHHHH
MEGNMAKLIIWYDNEAGFTNQLVRLLRKVGNSL
HCCCCEEEEEEECCCCCHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 2493629; 9384377; 8755892; 10658653; 10799476 [H]