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The map label for this gene is surE

Identifier: 78357383

GI number: 78357383

Start: 2359130

End: 2359909

Strand: Direct

Name: surE

Synonym: Dde_2340

Alternate gene names: 78357383

Gene position: 2359130-2359909 (Clockwise)

Preceding gene: 78357370

Following gene: 78357384

Centisome position: 63.24

GC content: 59.23

Gene sequence:

>780_bases
ATGTTCATTGCACTTACCAACGACGACGGCATTCAGGCGCCCGGACTGCGCGCCATGTACAAGGCACTGAAAGAAGCCGG
ACACACCGTGCAGGTGGTGGCCCCGGTCACCGAACAGTCGGCCGTGGGACACGCCGTGACCATAGCCCTGCCGCTGAGGG
TAAAAATATTTGCAGAAAACGGCTTTCAGGGCATGGGAGTATACGGCACCCCCACGGACTGCGTTAAACTGGGGCTGAAC
GCACTGCTGGACAAAAAACCCGACATTGTCGTTTCCGGCATAAACGCAGGTGCCAACGTGGGACCGGACATTCTCTATTC
CGGCACGGTATCGGCCGCCACCGAAGCGGCGCACATGGGCTATCCTTCGCTGGCAGTCTCGTACGACAACTTCAAACCGG
ACGACATCGCAGCCCATGCCCGCTTCGCTGTCGAAATAATGGAATCCATGCCGTGGCAATCGCTGCCGCCGCGCTGCGTG
CTTAACCTGAACCTGCCCGATGTCCCCATGCAGCAATGCAAAGGGCTTACCCTGTGCCCGCAGACAAGAGCTGTCTGGAA
AGACTGGTACGATCACCGCACCGACCCGCGGGGCAATTCCTACTGGTGGTTAAACGGTATCATACCTCCGGAAACAGTGG
CCGAAGGCACCGACAGAGACATGCTGACCCGCGGATACGCCACGCTGACCCCCCTGCGTTTCGACTTCACCGACAGGGAA
ACACTGGCCCGGCTGCAGCAGAATATGGACAGGCAGCGGCAGGGGTCTGAAGACCTTTGA

Upstream 100 bases:

>100_bases
CGCCCGGCGCAACAACCGGAAGCCATCCGCCGGCGGGGCACTCCGGCGTTGTGCGCACCGCAAAGCGGACAGTCATCATA
CCACCCCGTAGGGAGAATAC

Downstream 100 bases:

>100_bases
TTTTCTGCGGCTTGTCGTTTAAAGTGCCCGCGCTTTCATTGACAGGATGGTGTATCCCTCACTAGTGTGAAAGGGATAGA
GGCAGATTCGTGGAGTGTCG

Product: exopolyphosphatase / 3'-nucleotidase / 5'-nucleotidase

Products: NA

Alternate protein names: Nucleoside 5'-monophosphate phosphohydrolase

Number of amino acids: Translated: 259; Mature: 259

Protein sequence:

>259_residues
MFIALTNDDGIQAPGLRAMYKALKEAGHTVQVVAPVTEQSAVGHAVTIALPLRVKIFAENGFQGMGVYGTPTDCVKLGLN
ALLDKKPDIVVSGINAGANVGPDILYSGTVSAATEAAHMGYPSLAVSYDNFKPDDIAAHARFAVEIMESMPWQSLPPRCV
LNLNLPDVPMQQCKGLTLCPQTRAVWKDWYDHRTDPRGNSYWWLNGIIPPETVAEGTDRDMLTRGYATLTPLRFDFTDRE
TLARLQQNMDRQRQGSEDL

Sequences:

>Translated_259_residues
MFIALTNDDGIQAPGLRAMYKALKEAGHTVQVVAPVTEQSAVGHAVTIALPLRVKIFAENGFQGMGVYGTPTDCVKLGLN
ALLDKKPDIVVSGINAGANVGPDILYSGTVSAATEAAHMGYPSLAVSYDNFKPDDIAAHARFAVEIMESMPWQSLPPRCV
LNLNLPDVPMQQCKGLTLCPQTRAVWKDWYDHRTDPRGNSYWWLNGIIPPETVAEGTDRDMLTRGYATLTPLRFDFTDRE
TLARLQQNMDRQRQGSEDL
>Mature_259_residues
MFIALTNDDGIQAPGLRAMYKALKEAGHTVQVVAPVTEQSAVGHAVTIALPLRVKIFAENGFQGMGVYGTPTDCVKLGLN
ALLDKKPDIVVSGINAGANVGPDILYSGTVSAATEAAHMGYPSLAVSYDNFKPDDIAAHARFAVEIMESMPWQSLPPRCV
LNLNLPDVPMQQCKGLTLCPQTRAVWKDWYDHRTDPRGNSYWWLNGIIPPETVAEGTDRDMLTRGYATLTPLRFDFTDRE
TLARLQQNMDRQRQGSEDL

Specific function: Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates

COG id: COG0496

COG function: function code R; Predicted acid phosphatase

Gene ontology:

Cell location: Cytoplasm (Potential)

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the surE nucleotidase family

Homologues:

Organism=Escherichia coli, GI1789101, Length=240, Percent_Identity=43.3333333333333, Blast_Score=174, Evalue=5e-45,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): SURE_DESDG (Q30YV9)

Other databases:

- EMBL:   CP000112
- RefSeq:   YP_388832.1
- ProteinModelPortal:   Q30YV9
- SMR:   Q30YV9
- STRING:   Q30YV9
- GeneID:   3757351
- GenomeReviews:   CP000112_GR
- KEGG:   dde:Dde_2340
- NMPDR:   fig|207559.3.peg.2698
- eggNOG:   COG0496
- HOGENOM:   HBG600532
- OMA:   IILITND
- ProtClustDB:   CLSK705613
- BioCyc:   DDES207559:DDE_2340-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00060
- InterPro:   IPR002828
- Gene3D:   G3DSA:3.40.1210.10
- TIGRFAMs:   TIGR00087

Pfam domain/function: PF01975 SurE; SSF64167 SurE-like_Pase/nucleotidase

EC number: =3.1.3.5

Molecular weight: Translated: 28447; Mature: 28447

Theoretical pI: Translated: 5.31; Mature: 5.31

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
5.0 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
5.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFIALTNDDGIQAPGLRAMYKALKEAGHTVQVVAPVTEQSAVGHAVTIALPLRVKIFAEN
CEEEEECCCCCCCCCHHHHHHHHHHCCCEEEEEECCCCCCCCCEEEEEEEEEEEEEEECC
GFQGMGVYGTPTDCVKLGLNALLDKKPDIVVSGINAGANVGPDILYSGTVSAATEAAHMG
CCCCCCCCCCCHHHHHHHHHHHHCCCCCEEEECCCCCCCCCCCEEECCCHHHHHHHHHCC
YPSLAVSYDNFKPDDIAAHARFAVEIMESMPWQSLPPRCVLNLNLPDVPMQQCKGLTLCP
CCCEEEECCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCEEEECCCCCCCHHHCCCCEECC
QTRAVWKDWYDHRTDPRGNSYWWLNGIIPPETVAEGTDRDMLTRGYATLTPLRFDFTDRE
CHHHHHHHHHHCCCCCCCCCEEEECCCCCCHHHHCCCCHHHHHCCCCEECEEEECCCCHH
TLARLQQNMDRQRQGSEDL
HHHHHHHHHHHHHCCCCCC
>Mature Secondary Structure
MFIALTNDDGIQAPGLRAMYKALKEAGHTVQVVAPVTEQSAVGHAVTIALPLRVKIFAEN
CEEEEECCCCCCCCCHHHHHHHHHHCCCEEEEEECCCCCCCCCEEEEEEEEEEEEEEECC
GFQGMGVYGTPTDCVKLGLNALLDKKPDIVVSGINAGANVGPDILYSGTVSAATEAAHMG
CCCCCCCCCCCHHHHHHHHHHHHCCCCCEEEECCCCCCCCCCCEEECCCHHHHHHHHHCC
YPSLAVSYDNFKPDDIAAHARFAVEIMESMPWQSLPPRCVLNLNLPDVPMQQCKGLTLCP
CCCEEEECCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCEEEECCCCCCCHHHCCCCEECC
QTRAVWKDWYDHRTDPRGNSYWWLNGIIPPETVAEGTDRDMLTRGYATLTPLRFDFTDRE
CHHHHHHHHHHCCCCCCCCCEEEECCCCCCHHHHCCCCHHHHHCCCCEECEEEECCCCHH
TLARLQQNMDRQRQGSEDL
HHHHHHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA