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The map label for this gene is argS

Identifier: 78357338

GI number: 78357338

Start: 2314882

End: 2316537

Strand: Direct

Name: argS

Synonym: Dde_2295

Alternate gene names: 78357338

Gene position: 2314882-2316537 (Clockwise)

Preceding gene: 78357337

Following gene: 78357339

Centisome position: 62.06

GC content: 58.57

Gene sequence:

>1656_bases
ATGCGCGCAAAAAACCATCTGCAGACGGCACTGAAAGCCGTCGTGGCCGATCTGGAACTCCCGTGGCCCGATAAAGTTTC
CATCGAGCCGCCCAAGGACAAAAAATTCGGCGATCTTGCCGCCAATATCGCACTGGTGCTGGCCAAGCCGGCGGCGATGC
CCCCCCGCGAGCTTGCAGCACGTATCACGGAACGCCTGCAACAGAAATATCCCGAAATATCGGGAGTGGAGATAGCAGGT
CCGGGGTTCATCAACGTGACCTATGCGCCTGACTTCTGGCACAGGACAGTGCACATGGTGGAACAGGCAGGCGGACGTTT
CGGCAGTGTGAACGTGGGCAACGGGCGCAAAGTGCAGATCGAATATGTTTCCGCAAACCCCACAGGTCCTCTGCACATCG
GCCACGGCCGCGGAGCCGCCATAGGCGACAGTCTGGCGCGCATGATGCGCTTTGCCGGTTTTGAAACCAGCACCGAATAC
TACATCAACGATGCAGGACGCCAGATGCTGCTGCTGGGGGCCTCTGTCTACTACCGGGCAAAGCAGATCAAAGGTCTGGA
TGTGGCGGAACCGGAAGAATATTACCGCGGTGACTACATACGCGACATTGCGTCGGAAGTGCTCGGCTTTACTCCCGACC
TGCTGGAAAAACCCGAAGAAGAAGCGCTTGCCGTCTGCCAGAAATACGCCGTCGACACCATAATGGCCGGTATCCGGCAG
GATCTTGCCGACTTCTCCGTCAGCCACGATGTCTGGTTTTCCGAAAAATCGCTGGTGGAAACAGGTGCCGTGGACAAGAC
ATTCGACAGGCTGCGCCGGTCCGGTCTTGCCTATGAAGAAGACGGAGCCCTGTGGTTCCGGACCACTGATTTCGGCGATG
ACAAAAACCGAGTCCTGAAGAAATCCAACGGCTATCTGACGTACTTTGCGTCCGACATCGCCTACCACGACAACAAATAT
GACCGCGGGTTCGACCTGTGCGTCGACATATGGGGCGCCGACCACCACGGCTATGTTCCGCGCATGCGCGCCGCCGTACA
GGCGCTGGGCAAACCGGCAGACAGCTTCGATGTCATTCTGGTGCAGCTTGTCAACCTGCTGCGCAACGGTGAACAGGTGG
CCATGTCCACCCGCGCCGGTGAGTTCGAAACCCTTGCCGATGTGGTCAAGGAAGTAGGCGCCGATGCCGCGCGCTTCATG
TTTCTGTCGCGCAAAAGCGACAGCTCGCTGGACTTTGACCTTGAACTGGTCAAGCAGCGCTCCATGGACAACCCCGTGTA
CTACGTCCAGTATGCGCACGCCCGCATATGTTCCGTGCTGCGCAAAGCCGCAGAAAGGGGCACCACGCCTGAGACGCATT
CGGACGAAGAACTGCTGAAGCCCCTCGTGCATGCCGACGAAATCGACATGCTGCGTCTGGTCGACCGGTTCGAAGATACG
GTGGAGGCTGCCGCAACCAGTCTGAGCGTGCACCATATCAGCTACTATCTGCAGGAGCTTGCAAGCGCGCTGCACCGCTT
TTACGCCAACCATCCGGTGCTCAACGCTCCGGATGAACAGATTCTCAAAGCACGGCTTGCTCTGCTGCGTGCTGTGGCAC
AGGTTCTGCGCAACGGGCTGGACCTGCTTGGTGTCAGCGCGCCCGAGGCAATGTAG

Upstream 100 bases:

>100_bases
GAAGACGGAGGCGACCCAGTGCGGTCGCCTTTCCACGTCCAGACAACCGACGGAATCCGCCTCTTGCAGGCACATCATAC
TTAACAACAACGGTGGTACA

Downstream 100 bases:

>100_bases
CCGCTACCGGCATTATCCGTAACCTTCAGGCATCCGCATGAGCTTCAGCATCCGCAGTGAAAAAGGGTCCGCCGGCGCAC
GCCGGTTCATTATAGAAATG

Product: arginyl-tRNA synthetase

Products: NA

Alternate protein names: Arginine--tRNA ligase; ArgRS

Number of amino acids: Translated: 551; Mature: 551

Protein sequence:

>551_residues
MRAKNHLQTALKAVVADLELPWPDKVSIEPPKDKKFGDLAANIALVLAKPAAMPPRELAARITERLQQKYPEISGVEIAG
PGFINVTYAPDFWHRTVHMVEQAGGRFGSVNVGNGRKVQIEYVSANPTGPLHIGHGRGAAIGDSLARMMRFAGFETSTEY
YINDAGRQMLLLGASVYYRAKQIKGLDVAEPEEYYRGDYIRDIASEVLGFTPDLLEKPEEEALAVCQKYAVDTIMAGIRQ
DLADFSVSHDVWFSEKSLVETGAVDKTFDRLRRSGLAYEEDGALWFRTTDFGDDKNRVLKKSNGYLTYFASDIAYHDNKY
DRGFDLCVDIWGADHHGYVPRMRAAVQALGKPADSFDVILVQLVNLLRNGEQVAMSTRAGEFETLADVVKEVGADAARFM
FLSRKSDSSLDFDLELVKQRSMDNPVYYVQYAHARICSVLRKAAERGTTPETHSDEELLKPLVHADEIDMLRLVDRFEDT
VEAAATSLSVHHISYYLQELASALHRFYANHPVLNAPDEQILKARLALLRAVAQVLRNGLDLLGVSAPEAM

Sequences:

>Translated_551_residues
MRAKNHLQTALKAVVADLELPWPDKVSIEPPKDKKFGDLAANIALVLAKPAAMPPRELAARITERLQQKYPEISGVEIAG
PGFINVTYAPDFWHRTVHMVEQAGGRFGSVNVGNGRKVQIEYVSANPTGPLHIGHGRGAAIGDSLARMMRFAGFETSTEY
YINDAGRQMLLLGASVYYRAKQIKGLDVAEPEEYYRGDYIRDIASEVLGFTPDLLEKPEEEALAVCQKYAVDTIMAGIRQ
DLADFSVSHDVWFSEKSLVETGAVDKTFDRLRRSGLAYEEDGALWFRTTDFGDDKNRVLKKSNGYLTYFASDIAYHDNKY
DRGFDLCVDIWGADHHGYVPRMRAAVQALGKPADSFDVILVQLVNLLRNGEQVAMSTRAGEFETLADVVKEVGADAARFM
FLSRKSDSSLDFDLELVKQRSMDNPVYYVQYAHARICSVLRKAAERGTTPETHSDEELLKPLVHADEIDMLRLVDRFEDT
VEAAATSLSVHHISYYLQELASALHRFYANHPVLNAPDEQILKARLALLRAVAQVLRNGLDLLGVSAPEAM
>Mature_551_residues
MRAKNHLQTALKAVVADLELPWPDKVSIEPPKDKKFGDLAANIALVLAKPAAMPPRELAARITERLQQKYPEISGVEIAG
PGFINVTYAPDFWHRTVHMVEQAGGRFGSVNVGNGRKVQIEYVSANPTGPLHIGHGRGAAIGDSLARMMRFAGFETSTEY
YINDAGRQMLLLGASVYYRAKQIKGLDVAEPEEYYRGDYIRDIASEVLGFTPDLLEKPEEEALAVCQKYAVDTIMAGIRQ
DLADFSVSHDVWFSEKSLVETGAVDKTFDRLRRSGLAYEEDGALWFRTTDFGDDKNRVLKKSNGYLTYFASDIAYHDNKY
DRGFDLCVDIWGADHHGYVPRMRAAVQALGKPADSFDVILVQLVNLLRNGEQVAMSTRAGEFETLADVVKEVGADAARFM
FLSRKSDSSLDFDLELVKQRSMDNPVYYVQYAHARICSVLRKAAERGTTPETHSDEELLKPLVHADEIDMLRLVDRFEDT
VEAAATSLSVHHISYYLQELASALHRFYANHPVLNAPDEQILKARLALLRAVAQVLRNGLDLLGVSAPEAM

Specific function: Unknown

COG id: COG0018

COG function: function code J; Arginyl-tRNA synthetase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I aminoacyl-tRNA synthetase family

Homologues:

Organism=Homo sapiens, GI15149476, Length=618, Percent_Identity=26.2135922330097, Blast_Score=116, Evalue=5e-26,
Organism=Escherichia coli, GI1788184, Length=565, Percent_Identity=27.6106194690265, Blast_Score=136, Evalue=4e-33,
Organism=Caenorhabditis elegans, GI71985061, Length=604, Percent_Identity=23.0132450331126, Blast_Score=95, Evalue=8e-20,
Organism=Caenorhabditis elegans, GI71985068, Length=564, Percent_Identity=22.8723404255319, Blast_Score=89, Evalue=6e-18,
Organism=Saccharomyces cerevisiae, GI6320548, Length=572, Percent_Identity=26.5734265734266, Blast_Score=108, Evalue=2e-24,
Organism=Saccharomyces cerevisiae, GI6321883, Length=505, Percent_Identity=23.3663366336634, Blast_Score=99, Evalue=2e-21,
Organism=Drosophila melanogaster, GI28571570, Length=484, Percent_Identity=23.9669421487603, Blast_Score=75, Evalue=1e-13,

Paralogues:

None

Copy number: 789 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 800 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): SYR_DESDG (Q30Z04)

Other databases:

- EMBL:   CP000112
- RefSeq:   YP_388787.1
- ProteinModelPortal:   Q30Z04
- STRING:   Q30Z04
- GeneID:   3757306
- GenomeReviews:   CP000112_GR
- KEGG:   dde:Dde_2295
- NMPDR:   fig|207559.3.peg.2111
- eggNOG:   COG0018
- HOGENOM:   HBG695395
- OMA:   FDVYFHE
- ProtClustDB:   PRK01611
- BioCyc:   DDES207559:DDE_2295-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00123
- InterPro:   IPR001412
- InterPro:   IPR001278
- InterPro:   IPR015945
- InterPro:   IPR005148
- InterPro:   IPR008909
- InterPro:   IPR014729
- InterPro:   IPR009080
- Gene3D:   G3DSA:3.30.1360.70
- Gene3D:   G3DSA:3.40.50.620
- PANTHER:   PTHR11956
- PRINTS:   PR01038
- SMART:   SM00836
- TIGRFAMs:   TIGR00456

Pfam domain/function: PF03485 Arg_tRNA_synt_N; PF05746 DALR_1; PF00750 tRNA-synt_1d; SSF55190 Arg-tRNA-synth_Ic_N; SSF47323 tRNAsyn_1a_bind

EC number: =6.1.1.19

Molecular weight: Translated: 61402; Mature: 61402

Theoretical pI: Translated: 5.62; Mature: 5.62

Prosite motif: PS00178 AA_TRNA_LIGASE_I

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRAKNHLQTALKAVVADLELPWPDKVSIEPPKDKKFGDLAANIALVLAKPAAMPPRELAA
CCCHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCHHHHHHHHHHEEECCCCCCHHHHHH
RITERLQQKYPEISGVEIAGPGFINVTYAPDFWHRTVHMVEQAGGRFGSVNVGNGRKVQI
HHHHHHHHHCCCCCCEEEECCCEEEEEECCHHHHHHHHHHHHCCCCCCEEECCCCCEEEE
EYVSANPTGPLHIGHGRGAAIGDSLARMMRFAGFETSTEYYINDAGRQMLLLGASVYYRA
EEEECCCCCCEEECCCCCCHHHHHHHHHHHHHCCCCCCCEEEECCCCEEEEEHHHHHHHH
KQIKGLDVAEPEEYYRGDYIRDIASEVLGFTPDLLEKPEEEALAVCQKYAVDTIMAGIRQ
HHCCCCCCCCCHHHHCCHHHHHHHHHHHCCCHHHHCCCHHHHHHHHHHHHHHHHHHHHHH
DLADFSVSHDVWFSEKSLVETGAVDKTFDRLRRSGLAYEEDGALWFRTTDFGDDKNRVLK
HHHHHCCCCCCCCCCHHHHHHCCHHHHHHHHHHCCCCEECCCEEEEEECCCCCCHHHHHH
KSNGYLTYFASDIAYHDNKYDRGFDLCVDIWGADHHGYVPRMRAAVQALGKPADSFDVIL
CCCCEEEEEEHHHHHCCCCCCCCCEEEEEEECCCCCCCCHHHHHHHHHHCCCCCHHHHHH
VQLVNLLRNGEQVAMSTRAGEFETLADVVKEVGADAARFMFLSRKSDSSLDFDLELVKQR
HHHHHHHCCCCCEEECCCCCCHHHHHHHHHHHCCCHHHHHHEECCCCCCCCHHHHHHHHC
SMDNPVYYVQYAHARICSVLRKAAERGTTPETHSDEELLKPLVHADEIDMLRLVDRFEDT
CCCCCEEEEEHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHCCCHHHHHHHHHHHHHH
VEAAATSLSVHHISYYLQELASALHRFYANHPVLNAPDEQILKARLALLRAVAQVLRNGL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCC
DLLGVSAPEAM
CEEECCCCCCC
>Mature Secondary Structure
MRAKNHLQTALKAVVADLELPWPDKVSIEPPKDKKFGDLAANIALVLAKPAAMPPRELAA
CCCHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCHHHHHHHHHHEEECCCCCCHHHHHH
RITERLQQKYPEISGVEIAGPGFINVTYAPDFWHRTVHMVEQAGGRFGSVNVGNGRKVQI
HHHHHHHHHCCCCCCEEEECCCEEEEEECCHHHHHHHHHHHHCCCCCCEEECCCCCEEEE
EYVSANPTGPLHIGHGRGAAIGDSLARMMRFAGFETSTEYYINDAGRQMLLLGASVYYRA
EEEECCCCCCEEECCCCCCHHHHHHHHHHHHHCCCCCCCEEEECCCCEEEEEHHHHHHHH
KQIKGLDVAEPEEYYRGDYIRDIASEVLGFTPDLLEKPEEEALAVCQKYAVDTIMAGIRQ
HHCCCCCCCCCHHHHCCHHHHHHHHHHHCCCHHHHCCCHHHHHHHHHHHHHHHHHHHHHH
DLADFSVSHDVWFSEKSLVETGAVDKTFDRLRRSGLAYEEDGALWFRTTDFGDDKNRVLK
HHHHHCCCCCCCCCCHHHHHHCCHHHHHHHHHHCCCCEECCCEEEEEECCCCCCHHHHHH
KSNGYLTYFASDIAYHDNKYDRGFDLCVDIWGADHHGYVPRMRAAVQALGKPADSFDVIL
CCCCEEEEEEHHHHHCCCCCCCCCEEEEEEECCCCCCCCHHHHHHHHHHCCCCCHHHHHH
VQLVNLLRNGEQVAMSTRAGEFETLADVVKEVGADAARFMFLSRKSDSSLDFDLELVKQR
HHHHHHHCCCCCEEECCCCCCHHHHHHHHHHHCCCHHHHHHEECCCCCCCCHHHHHHHHC
SMDNPVYYVQYAHARICSVLRKAAERGTTPETHSDEELLKPLVHADEIDMLRLVDRFEDT
CCCCCEEEEEHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHCCCHHHHHHHHHHHHHH
VEAAATSLSVHHISYYLQELASALHRFYANHPVLNAPDEQILKARLALLRAVAQVLRNGL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCC
DLLGVSAPEAM
CEEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA