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The map label for this gene is selD [H]

Identifier: 78357268

GI number: 78357268

Start: 2265244

End: 2266137

Strand: Reverse

Name: selD [H]

Synonym: Dde_2225

Alternate gene names: 78357268

Gene position: 2266137-2265244 (Counterclockwise)

Preceding gene: 78357269

Following gene: 78357265

Centisome position: 60.75

GC content: 57.16

Gene sequence:

>894_bases
TTGCATTTTCCTGCGGGAAAAGCTCTTGTGCAGACAGTGGATTTTTTCACTCCCATTGTGAATGATCCCTACAAATTCGG
CAGGATAGCAGCTGCCAATGCGCTTTCAGACGTCTACGCCATGGGTGGAGAGCCGTGGTGTGCCATGAACATTGTTTGTT
TCCCCATCAAGGATTTGCCGCGGGATATTTTGCAGGCCATTATCCATGGGGGATACGACACATTGTGTGATGCCCGGGCT
TCACTTGCCGGCGGCCACAGTGTTGAAGACGATGAGATCAAGTTCGGCCTTTCCGTAACCGGTGTGGTAGACCCCGATGG
CTTTACTTCCAATGCCGCACTGCAGACCGGTGACCAGCTGTTGCTTACAAAGCCTTTGGGCACCGGCGTGCTTGCCACTG
CACTGAAGGCACGCTGGGACGGTGCGGACGAGATTGAGGAACTGGTTTTCAGGTGGGCAGGGCACCTTAATGCCGCTGCC
GGCTCGGTACTGCGCGCCATGCGGCTGAAAGCGGCTACGGACGTGACCGGTTTCGGGCTCGGAGGACACCTGCTGGAAAT
GGCTCTGGCGTCTTCACGCACAGTGCGGTTGTGGGCGCAGCGGGTTCCTGTCATCGAACGTGCCGCGGAGCTGGCCTCTA
TGGGGCTTGTTCCGGCGGGCAGCTACGCCAATAAGCATTACTGTGAATCCAAAGTCACCATTGATGCCGGTGTGCCTACA
ATAACGGCTGATCTGGTTTTTGATGCCCAGACTTCCGGCGGACTGGTGCTTGCCGTGCCGGGCAGCCGTCTGGATGAGGC
TGTTTCCAGACTGCATGATGCAGGCGAGTTTGTTGCCCACATTGGTGAAGTGACTGACCGGCAGTCCGCTTCCCTGCATC
TGGCCGCTGTATAG

Upstream 100 bases:

>100_bases
TCCGGGGGACCTGGAGCAGATTCTTGCTTCTCTGCCCGGACGCGCCCAGCATGACGACCGGCTGATTGTTGGCAGAGAAC
ATAATGAGGACGCGGCGATT

Downstream 100 bases:

>100_bases
GGGCAGCTGTATACGCAACACTTGCCAACCGGCTGCTGCGGTGGTATAGGTGCGCGCCTTCGATACGTGAGTGCTCATCT
CACATTTCTTTTTTTGTGCG

Product: selenophosphate synthase

Products: NA

Alternate protein names: Selenium donor protein; Selenophosphate synthase [H]

Number of amino acids: Translated: 297; Mature: 297

Protein sequence:

>297_residues
MHFPAGKALVQTVDFFTPIVNDPYKFGRIAAANALSDVYAMGGEPWCAMNIVCFPIKDLPRDILQAIIHGGYDTLCDARA
SLAGGHSVEDDEIKFGLSVTGVVDPDGFTSNAALQTGDQLLLTKPLGTGVLATALKARWDGADEIEELVFRWAGHLNAAA
GSVLRAMRLKAATDVTGFGLGGHLLEMALASSRTVRLWAQRVPVIERAAELASMGLVPAGSYANKHYCESKVTIDAGVPT
ITADLVFDAQTSGGLVLAVPGSRLDEAVSRLHDAGEFVAHIGEVTDRQSASLHLAAV

Sequences:

>Translated_297_residues
MHFPAGKALVQTVDFFTPIVNDPYKFGRIAAANALSDVYAMGGEPWCAMNIVCFPIKDLPRDILQAIIHGGYDTLCDARA
SLAGGHSVEDDEIKFGLSVTGVVDPDGFTSNAALQTGDQLLLTKPLGTGVLATALKARWDGADEIEELVFRWAGHLNAAA
GSVLRAMRLKAATDVTGFGLGGHLLEMALASSRTVRLWAQRVPVIERAAELASMGLVPAGSYANKHYCESKVTIDAGVPT
ITADLVFDAQTSGGLVLAVPGSRLDEAVSRLHDAGEFVAHIGEVTDRQSASLHLAAV
>Mature_297_residues
MHFPAGKALVQTVDFFTPIVNDPYKFGRIAAANALSDVYAMGGEPWCAMNIVCFPIKDLPRDILQAIIHGGYDTLCDARA
SLAGGHSVEDDEIKFGLSVTGVVDPDGFTSNAALQTGDQLLLTKPLGTGVLATALKARWDGADEIEELVFRWAGHLNAAA
GSVLRAMRLKAATDVTGFGLGGHLLEMALASSRTVRLWAQRVPVIERAAELASMGLVPAGSYANKHYCESKVTIDAGVPT
ITADLVFDAQTSGGLVLAVPGSRLDEAVSRLHDAGEFVAHIGEVTDRQSASLHLAAV

Specific function: Synthesizes selenophosphate from selenide and ATP [H]

COG id: COG0709

COG function: function code E; Selenophosphate synthase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the selenophosphate synthase 1 family. Class I subfamily [H]

Homologues:

Organism=Homo sapiens, GI24797148, Length=226, Percent_Identity=34.9557522123894, Blast_Score=109, Evalue=3e-24,
Organism=Homo sapiens, GI15011844, Length=274, Percent_Identity=31.3868613138686, Blast_Score=103, Evalue=1e-22,
Organism=Escherichia coli, GI1788062, Length=279, Percent_Identity=39.426523297491, Blast_Score=175, Evalue=4e-45,
Organism=Caenorhabditis elegans, GI17543426, Length=304, Percent_Identity=29.2763157894737, Blast_Score=102, Evalue=2e-22,
Organism=Drosophila melanogaster, GI24653602, Length=273, Percent_Identity=31.8681318681319, Blast_Score=108, Evalue=3e-24,
Organism=Drosophila melanogaster, GI24653604, Length=273, Percent_Identity=31.8681318681319, Blast_Score=108, Evalue=3e-24,
Organism=Drosophila melanogaster, GI28574119, Length=228, Percent_Identity=28.9473684210526, Blast_Score=89, Evalue=4e-18,
Organism=Drosophila melanogaster, GI28574118, Length=204, Percent_Identity=31.8627450980392, Blast_Score=79, Evalue=4e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000728
- InterPro:   IPR010918
- InterPro:   IPR016188
- InterPro:   IPR004536
- InterPro:   IPR023061 [H]

Pfam domain/function: PF00586 AIRS; PF02769 AIRS_C [H]

EC number: =2.7.9.3 [H]

Molecular weight: Translated: 31307; Mature: 31307

Theoretical pI: Translated: 5.12; Mature: 5.12

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MHFPAGKALVQTVDFFTPIVNDPYKFGRIAAANALSDVYAMGGEPWCAMNIVCFPIKDLP
CCCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCCCEEEEEEEEECHHHHH
RDILQAIIHGGYDTLCDARASLAGGHSVEDDEIKFGLSVTGVVDPDGFTSNAALQTGDQL
HHHHHHHHHCCHHHHHHHHHHHCCCCCCCCCCEEEEEEEEEEECCCCCCCCCHHCCCCEE
LLTKPLGTGVLATALKARWDGADEIEELVFRWAGHLNAAAGSVLRAMRLKAATDVTGFGL
EEECCCCCHHHHHHHHHCCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCCCCCC
GGHLLEMALASSRTVRLWAQRVPVIERAAELASMGLVPAGSYANKHYCESKVTIDAGVPT
HHHHHHHHHHCCCHHHHHHHHCCHHHHHHHHHHHCCCCCCCCCCCHHCCCEEEEECCCCE
ITADLVFDAQTSGGLVLAVPGSRLDEAVSRLHDAGEFVAHIGEVTDRQSASLHLAAV
EEEEEEEECCCCCCEEEEECCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEC
>Mature Secondary Structure
MHFPAGKALVQTVDFFTPIVNDPYKFGRIAAANALSDVYAMGGEPWCAMNIVCFPIKDLP
CCCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCCCEEEEEEEEECHHHHH
RDILQAIIHGGYDTLCDARASLAGGHSVEDDEIKFGLSVTGVVDPDGFTSNAALQTGDQL
HHHHHHHHHCCHHHHHHHHHHHCCCCCCCCCCEEEEEEEEEEECCCCCCCCCHHCCCCEE
LLTKPLGTGVLATALKARWDGADEIEELVFRWAGHLNAAAGSVLRAMRLKAATDVTGFGL
EEECCCCCHHHHHHHHHCCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCCCCCC
GGHLLEMALASSRTVRLWAQRVPVIERAAELASMGLVPAGSYANKHYCESKVTIDAGVPT
HHHHHHHHHHCCCHHHHHHHHCCHHHHHHHHHHHCCCCCCCCCCCHHCCCEEEEECCCCE
ITADLVFDAQTSGGLVLAVPGSRLDEAVSRLHDAGEFVAHIGEVTDRQSASLHLAAV
EEEEEEEECCCCCCEEEEECCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA